Clinical trials: Preterm Birth Complication
Premature Infants
Development of Preterm Infant Gut Microbiome
This study aims to explore the developmental of the gut microbiome in preterm infants as they grow and mature
- Trial name
- NCT03552952
- Testing
- No intervention
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Postpartum Depression, Lifestyle, Healthy
Nutrition and Physical Activity Intervention on Psychosocial Well-Being of Postpartum Mothers
This study aims to examine the effectiveness of nutrition and physical intervention to improve psychosocial well-being of postpartum mothers with preterm infants.
- Trial name
- NCT05444179
- Testing
- Mommies can Eat & Exercise with No Stress (MomEENS)
- Where
- Malaysia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universiti Teknologi Mara
Preeclampsia, Preterm Birth
Pregnancy Complications - A Probiotic Interventional Study
Investigators hypothesize that a) probiotics decrease the overall inflammatory state in the pregnant woman, especially in women with high risk pregnancies.
- Trial name
- NCT02693041
- Testing
- probiotic
- Where
- Sweden
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Infant Mortality, Preterm Birth
Antenatal Micronutrient Supplementation and Infant Survival
The purpose of this community-based randomized trial is to examine whether a daily antenatal and postnatal multiple micronutrient supplement given to women will enhance newborn and infant survival and health and other birth…
- Conditions
- Infant Mortality, Preterm Birth, Low Birth Weight, Neonatal Mortality
- Trial name
- JiVitA-3 (NCT00860470)
- Testing
- Iron (27 mg) - folic acid (600 ug), Multiple micronutrient
- Where
- 2 sites in United States, Bangladesh
- Volunteers
- 44,567 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Preterm, Infant ALL
Effects of Touch on Brain Connectivity and Metabolic Biomarkers in Preterm Infants
Improving the quality of life of preterm children by 2035 is the top priority of worldwide health organisations, including the WHO.
- Conditions
- Preterm, Infant ALL, Premature, Disease
- Trial name
- NCT05853991
- Testing
- osteopathic manipulative treatment, Active comparator
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Come Collaboration
Prematurity
PIOMI Effects on Preterm Infant Outcomes
Objective: This study aimed to investigate the effects of Premature Infant Oral Motor Intervention (PIOMI) on body weight gain, breastfeeding behavior, and length of hospital stay in preterm infants hospitalized in the neonatal…
- Trial name
- NCT07366190
- Testing
- Premature Infant Oral Motor Intervention (PIOMI), nursing care
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Premature Birth
Placental and Cord Blood Markers Associated With Premature Birth and Disorders of Premature Birth in Newborn Infants
The purpose of this study is to determine if changes in specific gene products in the placenta or cord/infant blood affect a baby's birth weight, increase the risk of premature birth, or increase the risk of developing diseases…
- Trial name
- NCT01439048
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Bronchopulmonary Dysplasia
The Role of Volatile Organic Compounds (VOCs), Airway Mucins and the Microbiome in the Early Prediction of Bronchopulmonary Dysplasia (BPD)
Bronchopulmonary dysplasia (BPD), the most common respiratory complication of extremely preterm birth, significantly impacts healthcare with high morbidity and mortality rates.
- Trial name
- INFANCY (NCT06342752)
- Testing
- Breath test, Throat swabs, Placental samples
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Infant, Premature, Infant, Late
Minor Increase Over Minimal Risk Research in NICU
Infants comprise a potentially vulnerable research population that received special consideration and protections under the US Code of Federal Regulations - Subpart D.
- Conditions
- Infant, Premature, Infant, Late, Infant, Preterm, Infant
- Trial name
- NCT02482012
- Testing
- Survey
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Fetal Growth Retardation, Low Birth Weight
BEP Supplementation Research in Bangladesh (JiVitA-BEP-IR)
The primary aim of the study is to evaluate the effect of fortified balanced energy and protein (BEP) supplementation vs. control (multiple micronutrient supplement, MMS) without targeting and with targeting (either by low…
- Conditions
- Fetal Growth Retardation, Low Birth Weight, Preterm Birth, Gestational Weight Gain
- Trial name
- Target-BEP (NCT05576207)
- Testing
- Balanced energy and protein supplement for pregnant women, Multiple Micronutrient Supplement for pregnant women
- Where
- Bangladesh
- Volunteers
- 3,390 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Pregnancy, Stillbirth
Zambian Preterm Birth Prevention Study
This prospective non-intervention cohort study will enroll women in the first or early second trimester of pregnancy and follow them through delivery (or end of pregnancy) and 1 year postpartum.
- Conditions
- Pregnancy, Stillbirth, Preterm Birth
- Trial name
- ZAPPS (NCT02738892)
- Where
- 2 sites in Zambia
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Inflammation, Pregnancy Related
Docosahexaenoic Acid (DHA) Supplementation in High Risk Pregnancies
Purpose: Determine the effects of maternal docosahexaenoic acid (DHA) supplementation during pregnancy on levels of DHA, synaptamide (novel anti-inflammatory metabolite), and inflammatory biomarkers during pregnancy and at…
- Trial name
- NCT04069195
- Testing
- DHA supplement, Corn Oil: Soybean Oil
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Immature Newborn, Premature Birth
Gestational Age Assessment Tool
In the UK and worldwide many babies are born without carers knowing their gestation as the mothers will not have had good antenatal care. It is possible to estimate gestation but this requires a detailed clinical exam.
- Trial name
- GestATion (NCT02534194)
- Testing
- Image acquisition
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Feeding Behavior, Mother-Child Relations
Examining the Effect of Occupational Therapy-Based Parent Coaching on Feeding Problems in Children With a Preterm Birth
Feeding problems are common in children with a history of premature birth, and these problems continue into early childhood. Feeding problems are affected by many biopsychosocial factors, and the context in which feeding takes…
- Conditions
- Feeding Behavior, Mother-Child Relations, Feeding and Eating Disorders
- Trial name
- NCT06266507
- Testing
- Ergotherapy Based Parent Coaching, Informative Brochure Distribution
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Overweight, Obesity, Small for Gestational Age, Prematurity
Novel Screening Tools For the Evaluation and Management of Malnourished Children in the Developing World
The purpose of this study is to evaluate the accuracy of a new device that may be used for the evaluation and management of malnourished infants and children.
- Trial name
- NCT02449408
- Testing
- Measurement of leptin and adiponectin obtained through blood sampling via venipuncture or finger/heelstick using novel screening tool
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Duke University
Local or Systemic Signs for Infection, Preterm Birth
Vaginal, Oral and Systemic Inflammation in Preterm Birth
The prevalence of preterm birth is not decreasing in the last decades despite of improving health care. Intrauterine infections are important in the etiology of preterm birth but the interconnection of systemic inflammation and…
- Trial name
- NCT01142752
- Where
- Switzerland
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Complication Due to Immunization
Cardio-respiratory Events and Inflammatory Response After Primary Immunization in Preterm Infants
Background: Inflammation may depress respiration in neonates. The aim of this study was to establish a link between post-immunization inflammation and cardio-respiratory events (CRE).
- Trial name
- NCT02726178
- Testing
- Advil® Pediatric drops for infants
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Preterm Birth
Physical Exam Indicated Cerclage in Singleton Gestation 24 Weeks to 25 Weeks and 6 Days Gestation
RCT assessing preterm delivery rate in singleton pregnancies having a physical-exam indicated cerclage placed between 24 weeks and 25 weeks and 6 days.
- Trial name
- NCT05501938
- Testing
- Physical Exam Indicated Cerclage
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Anemia, Intrauterine Growth Retardation
Impact of Pre-pregnancy Micronutrient Supplementation on Maternal and Child Outcomes
The study evaluates the efficacy of providing weekly iron-folate (IFA) supplements or Multiple Micronutrient (MM) supplements before pregnancy in increasing birth weight and duration of gestation as well as maternal and infant…
- Conditions
- Anemia, Intrauterine Growth Retardation, Preterm Delivery, Iron Deficiency
- Trial name
- NCT01665378
- Testing
- Multiple Micronutrient, Iron and Folic Acid, Folic Acid
- Where
- Vietnam
- Volunteers
- 5,011 people, healthy volunteers welcome
- Sponsor
- Emory University
Milk Production
A Trial Comparing Two Breast Pumps in Mothers Expressing Milk for Their Preterm Infants
This is a randomised controlled trial investigating the performance of two, 'state of the art' electric breast pumps in mothers who have delivered preterm infants.
- Trial name
- NCT00887991
- Where
- United Kingdom
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Institute of Child Health