Clinical trials: Preterm Birth Complication
Premature Birth
LATe Cerclage in High-risk Pregnancies (LATCH)
The goal of this clinical trial is to determine whether cervical cerclage reduces the risk of preterm birth in patients with a short transvaginal ultrasound (TVU) cervical length (CL) ≤25mm between 24 0/7-26 6/7 weeks.
- Trial name
- LATCH (NCT06036446)
- Testing
- Cervical cerclage, Vaginal Suppository Progesterone
- Where
- 2 sites in United States
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Preterm Pregnancy
Cervical Length and Uterocervical Angle as Predictors of Spontaneous Preterm Birth
This prospective study was carried out on 263 pregnant females aged from 19 to 35 years old carrying singleton, and uncomplicated pregnancy. TVS examination was performed in all cases at 28 and 32 weeks of gestation.
- Trial name
- NCT06403059
- Testing
- Cervical Length, Uterocervical Angle
- Where
- Egypt
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Preterm Infant
Growth and Safety of a Two-stage Feeding System in Preterm Infants
This study evaluates the safety and suitability of the two-stage feeding system in preterm infants.
- Trial name
- NCT03728764
- Testing
- Preterm infant formula
- Where
- 4 sites in Czechia, Poland and 1 more
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Preterm Infant, Term Infant
C-UCM and Cerebral Oxygenation and Perfusion
In this randomized controlled Pilot study the effects of cut-umbilical cord milking on cerebral oxygenation and perfusion measured via near-infrared spectroscopy (NIRS) and the effects on stroke volume (SV) and cardiac output…
- Conditions
- Preterm Infant, Term Infant, Transition
- Trial name
- NCT03748914
- Testing
- Intervention Group, Control Group
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Preeclampsia, Pregnancy Related
Low Dose Aspirin for Preterm Preeclampsia Preventionmg/day Dose in High-risk Patients
This will be a randomized, open-label, controlled trial of patients at high risk of developing preeclampsia examining 81 mg/day vs 162mg/day daily acetylsalicylic acid (ASA) use.
- Trial name
- NCT05514847
- Testing
- Aspirin 81Mg Ec Tab, Aspirin 162Mg Ec Tab
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Breast Feeding, Breast Milk Collection
Effect of Breast Milk Circadian Properties on Infant's Growth Parameters and Absorption of Nutrients
The most ideal method for providing breast milk is breastfeeding. However, it may be necessary to express breast milk for reasons such as the newborn being in an intensive care unit, the mother being hospitalized for any reason…
- Trial name
- The (NCT06342674)
- Testing
- Giving breast milk to the newborn according to the circadian rhythm, Usual care
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Vitamin d Deficiency, Preeclampsia
25- Hydroxyvitamin D Levels in Pregnancy and Effects on Pregnancy Related Disorders
Evaluation of 25- Hydroxyvitamin D levels in pregnant women in Austria and potential related disorders Hypothesis: Austrian pregnant women are Vitamin D deficient Present vitamin D supplementation in pregnancy is insufficient…
- Conditions
- Vitamin d Deficiency, Preeclampsia, Preterm Delivery, Gestational Hypertension
- Trial name
- VIDIS (NCT04637880)
- Where
- Austria
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Preterm Birth, Psychological Distress
Expected and Actual Preterm-Birth and Parental Distress: Impact on Children's Mental Health
The purpose of the present study is the assessment of the mental health and cognitive development of children 6-11 years after premature or term birth.
- Conditions
- Preterm Birth, Psychological Distress, Mental Health, Cognitive Functioning
- Trial name
- NCT06627140
- Testing
- Diagnostic procedures
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Goethe University
Premature Babies
BEADI - The Bliss Cluster Randomised Control Trial on the Effects of Active Dissemination of Information (BEADI)
BEADI is a dissemination trial, on standards of care of premature babies. The main objective of BEADI is to assess whether an innovative 'active' strategy for the dissemination of neonatal information (evidence reviews…
- Trial name
- BEADI (NCT00831168)
- Testing
- Effects of Active Dissemination
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Confidential Enquiry into Maternal and Child Health
Preterm Birth
Maternal Gut Microbiome (MGM) Study of Diet, the Gut Microbiome and Preterm Birth
The purpose of this study is to determine whether diet and the gut microbiome play a role in spontaneous preterm birth (SPTB), namely delivery of the fetus prior to 37 weeks gestation.
- Trial name
- MGM (NCT02560246)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cervical Insufficiency
Relation of the Area of Cerclage With Preterm Birth
This study is planned prospectively in pregnancies who applied to Etlik Zübeyde Hanım Women's Health Care, Training and Research Hospital which is a teritiary hospital with 15.000 births anually, between January 2022 and January…
- Trial name
- NCT05220839
- Testing
- Type of cerclage procedure Mc Donald
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital
Premature Birth, Obstructive Lung Disease
Pulmonary Outcomes of Bronchopulmonary Dysplasia in Young Adulthood
Preterm birth alters the normal sequence of lung development with lasting respiratory consequences. It is still unclear whether observed respiratory morbidities in preterm born individuals reflect sequelae from a non-progressive…
- Conditions
- Premature Birth, Obstructive Lung Disease, Bronchopulmonary Dysplasia
- Trial name
- NCT02820818
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Premature Birth
The Benefit in Terms of Improvement in Haemoglobin Level at 6 Months in Premature Babies Receiving Alternate Iron Substitution 4 Times a Week Compared to a Daily Substitution
BienFer is a double-blinded randomized controlled trial about iron substitution and abdominal pain. Premature babies and low birth weight babies have lower iron stores than term newborns and are therefore at greater risk of iron…
- Trial name
- BienFER (NCT06624709)
- Testing
- Iron Supplement
- Where
- 2 sites in Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Riccardo Pfister
Preterm Birth, Feeding Behavior
Preterm Infant Oral Motor Intervention (PIOMI)
The purpose of this research; The aim of this study is to examine the effects of oral motor intervention (PIOMI) and combined kangaroo care applied to preterm babies on weight gain, oral feeding skills, transition to full oral…
- Trial name
- NCT06259604
- Testing
- PIOMI, PIOMI+kangaroo care
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Premature Birth
Effect of Presenting Survival Information as Text or Pictograph During Periviable Birth Counseling
Women recruited from the internet will be put in a hypothetical situation of being in labor at 22 weeks of pregnancy, and presented with information on the likelihood of survival and chance of disability for babies born at this…
- Trial name
- NCT04859114
- Testing
- Format of outcome data presentation, Displayed chance of survival
- Where
- United States
- Volunteers
- 1,052 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Preterm Birth
Relationship Between Plasma Concentration of Hydroxyprogesterone Caproate (17-OHPC) and Preterm Birth
The study plans to determine the relationship between plasma concentrations of 17-OHPC hydroxyprogesterone caproate (17-OHPC) and the rate of preterm birth.
- Trial name
- PRO (NCT03292731)
- Testing
- 17-Hydroxyprogesterone caproate 250mg or 500 mg., Safety study of 500 mg dose.
- Where
- 5 sites in United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Steve N. Caritis, MD
Neonatal Skin Conditions
Effect of Different Materials Used in Orogastric Tube Removal on Skin Condition in Premature Babies
While medical adhesives provide fixation of devices and catheters in neonatal intensive care, problems such as disruption of skin integrity are frequently encountered when removed.
- Trial name
- NCT06280326
- Testing
- Sunflower oil, Slicone based spray
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Magnetoencephalography, Optical Pump Magnetometer
Magnetoencephalography by Optical Pumping Magnetometer
MagnetoEncephaloGraphy (MEG) is a method of recording brain activity with high temporal resolution and good spatial resolution, compared to current recording techniques such as ElectroEncephaloGraphy (EEG).
- Conditions
- Magnetoencephalography, Optical Pump Magnetometer, Neonate, Premature
- Trial name
- MEG OPM (NCT05835817)
- Testing
- Magnetoencephalography
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Coronary Artery Disease
A Multi-omics Study of "Healthy" Premature CAD Patients
The goal of this multi-center observational clinical trial is to investigate the genetic risk factors of patients with premature CAD and none traditional CAD risk factors through a multi-omics approach.
- Trial name
- NCT06362278
- Testing
- multi-omics studies
- Where
- 3 sites in China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Premature Birth, Fetal Growth Retardation
NACER II: Reducing Prenatal Exposures to Household Air Pollution in Rural Guatemala Through a Gas Stove/Behavior Intervention to Improve Neonatal Health
Greater efforts are needed to bring affordable, clean stoves and adaptive behavioral strategies to the millions of households worldwide that continue to burn solid cooking fuels using inefficient stoves.
- Conditions
- Premature Birth, Fetal Growth Retardation, Infections, Respiratory, Exposure to Environmental Pollution, Non-occupational
- Trial name
- NCT02812914
- Testing
- Low-cost gas stove, Peer education classes, Resource-intensive behavioral intervention approach
- Where
- Guatemala
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco