Clinical trials: Preterm Neonate Analgesia
Pain, Postoperative, Premature Infant
Postoperative Pain Control & Relief in Neonates
Pain control for newborns has made significant improvements over the last 30 years. The use of narcotics remains the standard of care for neonates undergoing minor and major surgeries.
- Conditions
- Pain, Postoperative, Premature Infant, Opioid Use
- Trial name
- POPCORN (NCT03677830)
- Testing
- Acetaminophen, Saline
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Premature Birth, Newborn
Pain Management in Neonatal Intensive Care Units by Studying the Autonomic Balance
Fight against the pain caused by the disease or by the diagnostic and therapeutic procedures is a daily and essential concern for the caregiver neonatologist.
- Trial name
- NIPE-DOL (NCT02764424)
- Testing
- NIPE (MDoloris®)
- Where
- France
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Meningitis
Lumbar Punctures in Neonates: Improving Success Rates and Minimizing Pain
The purpose of this study is to compare two medications used to numb an infant's back when performing a lumbar puncture. A lumbar puncture (LP) is often needed in newborns to obtain cerebrospinal fluid (CSF).
- Trial name
- NCT01606150
- Testing
- 1% lidocaine, topical lidocaine
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Pain Management
Non-Pharmacological Nursing Pain Management for Preterm Infants
A randomized controlled trial will be conducted to examine the effect of non-pharmacological nursing pain management strategies in alleviating pain among preterm infants.
- Trial name
- NCT05947877
- Testing
- Non-pharmacological pain management strategies
- Where
- Iraq
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Pain
Premature Newborn Pain Management: The Effects of Breast Milk Odor and White Noise
This study will conduct to evaluate the effect of using white noise and breast milk odor on pain during heel lance procedure in premature newborns. This study is a randomized controlled trial.
- Trial name
- NCT05444608
- Testing
- Breast milk olfactory stimulation, White noise auditory stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ankara University
Post Procedural Pain Management in Neonates
Comparison of Minimal Effective Dose of Sucrose for Pain Relief in Neonates After Minor Procedure
Type of Study: Randomized Controlled Trial Aim: To compare the effectiveness of two doses of sucrose solution for pain relief in neonates after minor procedures.
- Trial name
- NCT06446323
- Testing
- 0.2 ml dose of sucrose
- Where
- Pakistan
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Neonatal Disease, Pain, Acute
The Role of Time Interval Elimination on Pain Control of Preterm Infants by Sucrose Administration
Purpose. It has been demonstrated clearly that sucrose solutions given before a minor painful procedure can reduce pain among newborns.
- Trial name
- NCT05465694
- Testing
- 2-minute-time interval of per oral 24% sucrose, no time interval of per oral 24% sucrose
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Pain
Evaluation of Analgesia With EMLA and Glucose Oral Solution
In this randomized controlled study the investigators intended to compare analgesic effects of EMLA and/or oral glucose in 60 preterm neonate during arterial function and PICC installation.
- Trial name
- NCT00808054
- Testing
- EMLA
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Infant, Newborn, Infant, Premature
Effect of a Vibratory Stimulus on Mitigating Nociception-specific Responses to Skin Puncture in Neonates
The assessment and treatment of pain in neonates remains a challenge. In an effort to improve the quality of care while limiting opioid-related adverse effects, this study aims to determine the efficacy of a non-pharmacological…
- Conditions
- Infant, Newborn, Infant, Premature, Pain Perception, Pain Measurement
- Trial name
- NCT04050384
- Testing
- Baby GentleStick
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Lance M Relland, MD, PhD