Clinical trials: Preterm Premature Rupture of Membrane
Fetal Membranes, Premature Rupture, Induced Labor
Intracervical Catheters for Induction of Labour in Women With Prelabour Rupture of Membranes at Term
The purpose of this study is to examine the feasibility of using intracervical balloon catheters for cervical ripening as part of labour induction in healthy, GBS-negative women with prelabour rupture of membranes at term.
- Trial name
- IC-PROM (NCT00890630)
- Testing
- Intracervical Balloon Catheter, Oxytocin
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- McMaster University
Pregnant Woman With Premature Rupture of Amnion Membranes
A Comparison of Rapid Immunoassay Tests for the Detection of Ruptured Membranes
Specific objectives include analysis of performance of ROM Plus® in diagnosing ROM, as compared to Amnisure® and the conventional clinical assessment confirmed by a thorough chart review after delivery.
- Trial name
- NCT01668472
- Where
- Sri Lanka
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colombo
Premature Rupture of Membranes at Term
Comparison of Misoprostol and Prostaglandin E2 (PGE2) Gel for Induction of Labour in Premature Rupture of Membranes at Term
The purpose of this study is to determine whether induction of labor with vaginal misoprostol application will result in fewer cesarean deliveries than vaginal PGE2 gel application in women with premature rupture of membranes at…
- Trial name
- NCT00355303
- Testing
- Misoprostol, PGE2 gel
- Where
- India
- Volunteers
- 932 people
- Sponsor
- Nilratan Sircar Medical College
Pregnancy Complications
Diamine Oxidase and Adverse Pregnancy Outcomes
In normal pregnancies, blood histamine concentration remains within normal values; however, the serum histaminolytic activity is increased.
- Trial name
- NCT06281366
- Where
- Spain
- Volunteers
- 75 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Women Admitted to Labor and Delivery for the Management of Preterm Labor and/or Preterm Premature Rupture of Membranes (PPROM)
Fetal Thymus Involution as a Predictor of Adverse Neonatal Outcomes
The thymus gland is a specialized organ in the chest that plays a central role in the adaptive immune system throughout development until puberty. In response to stress, the fetal thymus gland may shrink, or involute.
- Trial name
- TIPS (NCT01975792)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Pennsylvania
Premature Rupture of Membranes, Enterobacteriaceae
Prevalence of Carriage of Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacteria in Preterm Premature Rupture of Membranes : A French Multicenter Cohort Study
This study looks at how common certain antibiotic-resistant bacteria (called extended-spectrum beta-lactamase-producing Enterobacteriaceae, or E-BLSE) are in pregnant women who experience premature breaking of their water before…
- Conditions
- Premature Rupture of Membranes, Enterobacteriaceae, Beta-Lactams, Drug Resistance, Bacterial
- Trial name
- NCT07200999
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Premature Rupture of Membrane
Erythromycin Versus Azithromycin for Preterm Prelabor Rupture of Membranes
The goal of this study is to help identify the best antibiotic treatment for pregnant people when their water breaks prematurely (a condition abbreviated as PPROM).
- Trial name
- PRACET (NCT06273891)
- Testing
- Erythromycin, Azithromycin
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- Inova Health Care Services
Fetal Membranes, Premature Rupture
Myometrial Thickness as a Predictor for the Latency Interval in PPROM
100 women divided into 3 groups: Group I: included 50 women with preterm premature rupture of membranes (PPROM, n=50) with gestational age from 24 to 34 weeks.
- Trial name
- NCT02380560
- Testing
- Ultrasonographic examination
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Labor Complication
Intrapartum Ultrasound in Labor: Sonography Only, Few Internal Examinations
This is a prospective, randomized trial to determine whether the use of sonographic parameters during labor results in less intrapartum infection compared to traditional invasive examination.
- Trial name
- SOFIE (NCT06261710)
- Testing
- Sonography in labour
- Where
- Germany
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- Larry Hinkson
Preterm Premature Rupture of Membrane
The Value of Amniopatch in Preterm Premature Rupture of Membranes
A randomized controlled trial that involved 100 women diagnosed with PPROM between 24 and 34 weeks of gestational age. Participants were randomized equally into 2 groups.
- Trial name
- NCT03473210
- Testing
- Antibiotics, Corticosteroid, Amniopatch
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University