Clinical trials: Prevention
Hepatitis B
Effectiveness of Two Hepatitis B Vaccines in HIV-negative Youths
This study will evaluate 2 licensed vaccine products (Recombivax and Twinrix) given in a two-dose schedule to youth at risk for hepatitis B and HIV infection to evaluate immunogenicity of the products in this population, barriers…
- Trial name
- NCT00107042
- Testing
- Recombivax, Twinrix
- Where
- 11 sites in United States, Puerto Rico
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Influenza
Vitamin D and the Influenza Epidemic
Subjects included in ongoing vitamin d intervention trials were asked by questionnaire if they were ill with influenza during the winter season 2009/2010 to see if vitamin d supplementation prevented flu like disease.
- Trial name
- NCT01182870
- Testing
- choleclaciferol
- Where
- Norway
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Colorectal Neoplasms
Colonoscopic Removal of Aberrant Crypt Foci: a Prospective, Randomized, Blinded Trial
We hypothesized that aberrant crypt foci (ACF) are precursors of colon cancer; their prevention would correlate with cancer risk and their elimination would reduce that risk.
- Trial name
- NCT00623883
- Testing
- Surgical removal of ACF, Colonoscopic evaluation only
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- National Naval Medical Center
Frailty
Feasibility and Effects of Preventive Home Visits for Older Adults
The goals of this project are to implement an innovative intervention for older adults and assess both its feasibility and effects on health and well-being.
- Trial name
- NCT00985283
- Testing
- Preventive home visit, minimal intervention
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Injection Pain Prevention, Injection Pain
The Effect of Simultaneous Versus Sequential Intramuscular Vaccine Injections on Pain Levels in Infants
This study was designed as a randomized controlled trial comparing simultaneous and sequential administration of intramuscular vaccines in infants.
- Trial name
- NCT07455305
- Testing
- Simultaneous injection, Sequential injection
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Mental Health Promotion, Emotional Intelligence
Two Tutorial Action Programs, Incidental and Structured, on the General Welfare of Elementary School Students.
The aim of this paper is twofold: on the one hand, to test the effectiveness of a structured emotional education program in second, third and fourth grade primary school students and, on the other hand, to test the differential…
- Conditions
- Mental Health Promotion, Emotional Intelligence, Self-Concept, Emotional and Behavioral Problems
- Trial name
- NCT06131229
- Testing
- Structured emotional education program (PEE), Incidental tutorial action based on the school's regular curriculum (PCO)
- Where
- Spain
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- OIHANA SAGASTI ARRIEN
Sarcopenia, High Blood Pressure
The Impact of a Resistance Training Intervention on Blood Pressure Control in Older Adults With Sarcopenia
Current prevention and treatment of high blood pressure (BP) in sarcopenia, by non-pharmacological approaches remain limited and are far from optimal.
- Conditions
- Sarcopenia, High Blood Pressure, Hypertension
- Trial name
- INERTIA (NCT04255745)
- Testing
- progressive resistance training
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Diabetes
Happier Feet- A Smart Insole for Diabetic Foot Ulceration Prevention
This study aims to design, develop, and evaluate a smart insole to predict the formation of diabetic foot ulcers (DFUs) in diabetic participants at risk of developing them.
- Trial name
- Happier Feet (NCT05865353)
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Human Immunodeficiency Virus
Mobile-health (mHealth) Intervention to Support HIV Self-testing and PrEP Uptake Among Young Men Who Have Sex With Men
The proposed study will involve adolescent (17-24 years old) men who have sex with men (described as YMSM hereafter) who meet eligibility criteria to participate.
- Trial name
- NCT04865341
- Testing
- IMB, Information-Only Control
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
HIV, Gonorrhea
Keep It Up! 2.0: A Comparison of Two Online HIV Intervention Programs for Young Men Who Have Sex With Men
Young men who have sex with men (YMSM) account for almost 70% of HIV diagnoses among all young people in the U.S. and are alone in facing an increasing rate of infections.
- Conditions
- HIV, Gonorrhea, Chlamydia
- Trial name
- KIU! (NCT01836445)
- Testing
- Keep It Up!, HIV Knowledge Control
- Where
- 3 sites in United States
- Volunteers
- 901 people, healthy volunteers welcome
- Sponsor
- Northwestern University
HIV Prevention, Transgender Women
Long-acting Biomedical HIV Prevention in Transgender Women
Transgender women (TW) have unique challenges related to HIV prevention medication adherence. Left unaddressed, these challenges will prevent TW from accessing the promising long-acting HIV prevention tools in the development…
- Trial name
- NCT03856580
- Testing
- Alternative long-acting PrEP injection strategies, mHealth adherence app
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Prevention of Malaria Transmission and Clinical Malaria
Dose-Escalating Study of Pfs230D1 in Combination With R21 in Matrix-M in African Adults
This is a Phase 1, individually randomized, double-blind, dose escalating study designed to evaluate the safety, tolerability, and immunogenicity of Pfs230D1 conjugate vaccines, R21 nanoparticle vaccine, or their combination…
- Trial name
- NCT06507605
- Testing
- R21, Pfs230D1-CRM197, Pfs230D1-EPA
- Where
- Mali
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Serum Institute of India Pvt. Ltd.
Healthy
Avene Compact Honey for Prevention of Pigmentation From Visible Light
The main objective of the study is to assess the efficacy of Avène Compact Honey in preventing pigmentation induced by visible light in subjects with a phototype III or IV.
- Trial name
- NCT01448122
- Testing
- Avene Compact Honey SPF 50
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Suicide Awareness, Suicidal Ideation
"Youth Aware of Mental Health" in Galicia
The goal of this interventional study is to assess the effectiveness of the universal suicide prevention program "Youth Aware of Mental Health" in 3rd-year secondary education students in Galicia.
- Conditions
- Suicide Awareness, Suicidal Ideation, Suicide, Attempted, Depressive Symptoms
- Trial name
- YAM (NCT06251037)
- Testing
- Youth Aware of Mental Health in Galicia
- Where
- 68 sites in Spain
- Volunteers
- 4,453 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Opioid Related Disorders
Computer-based Prescription Opioid Abuse Prevention for Adolescents
The investigators are developing an interactive, web-based program for youth ages 12-17 focused on the prevention of prescription opioid abuse because to the investigators knowledge, no science-based, interactive program focused…
- Trial name
- NCT02737696
- Testing
- Web-based prescription opioid prevention for adolescents, JustThinkTwice.gov website (DEA)
- Where
- United States
- Volunteers
- 435 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Stigma, Social
Project Orleu: Reducing Intersectional and HIV Stigma Among Health Care Providers and High Risk Women Who Use Drugs in Kazakhstan
Suboptimal linkage to and retention in HIV prevention and care is prevalent among high-risk women who use or inject drugs in both the US and globally, including high HIV incidence contexts like Kazakhstan; addressing HIV and…
- Trial name
- NCT06932796
- Testing
- Health Care Provider Stigma Training and Clinic-Based Messaging Campaign
- Where
- Kazakhstan
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Columbia University
Knee Valgus
Integrated Training Program On Jump Performance And Knee Valgus In Youth Football Players
This study aimed to investigate the effects of stretching, strength, and plyometric exercise training programs, applied in addition to regular training, on jumping performance and knee valgus values in football players.
- Trial name
- NCT07009041
- Testing
- Strength training program, Stretching exercises program, Plyometric exercises program
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Diabetes Mellitus, Type 1
Anti-viral Action Against Type 1 Diabetes Autoimmunity
The study GPPAD-05 AVAnT1A is a phase 4 clinical trial intending to enroll 2252 children, who will be randomly assigned to receive COVID-19 vaccination (Comirnaty® 3 μg Omicron XBB.1.5 or new variant Comirnaty vaccines ) or…
- Trial name
- NCT06452654
- Testing
- Comirnaty Injectable Product, Sodium Chloride 0.9% Inj
- Where
- 9 sites in Austria, Belgium and 3 more
- Volunteers
- 2,252 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Children, Health Education
"Eye" Education for Parents and Myopia Control in Children
This is a randomized controlled trial aimed to explore the effect of behavioral interventions based on doctors' and nurses' health education on the onset and development of myopia in children's.
- Conditions
- Children, Health Education, Anxiety
- Trial name
- NCT06652594
- Testing
- Eye Education Intervention, Control
- Where
- China
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Intimate Partner Violence (IPV), Sexual Violence
Evaluation of a Sexual Violence and Intimate Partner Violence Primary Prevention Program Implemented in Drinking Establishments
The goal of this project is to evaluate the effectiveness of Safe Night Out, a community-level primary violence prevention program offered in drinking establishments in the Sacramento region of California.
- Conditions
- Intimate Partner Violence (IPV), Sexual Violence, Alcohol, Safety
- Trial name
- NCT07434856
- Testing
- Safe Night Out Program, No Safe Night Out
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
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