Clinical trials: Prevention of Dental Caries
Dental Caries
Evaluation of Antimicrobial Efficacy of Green Tea, Garlic With Lime, Pomegranate Extract and Chlorhexidine Mouth Rinses in a Group of Egyptian Children (In-Vivo Study)
the aim of the clinical trial is to evaluate the antimicrobial efficacy of the herbal mouth rinses against chlorhexidine mouth rinse.
- Trial name
- NCT05841589
- Testing
- Green tea extract mouth rinse, Garlic with lime extract mouth rinse, Pomegranate extract mouth rinse
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- omnia sayed
Dental Caries in Children
The Effectiveness of Dental Health Home Visits on Caries Prevention in Young Children
Tooth decay affects 75% of Malaysian preschool children, most of which remain untreated. Untreated decay can cause pain, and impair nutritional status and physical growth.
- Trial name
- NCT04885348
- Testing
- Intervention Group (Dental Home Visits + Dental Home Education Leaflets), Control Group (Dental Home Education Leaflets)
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Ministry of Education, Malaysia
Dental Caries
Effectiveness of Fluoride Varnish in Prevention of Dental Caries in School Children
Despite the availability of free health dental service in Sri Lanka, the prevalence and severity of dental caries among 6year old school children stand at a very high level according to the results of national oral health survey…
- Trial name
- NCT02877888
- Testing
- fluoride varnish 22600ppm
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Peradeniya
Dental Caries, Prevention
Sealant Application by Interns After Tele-demonstration
Abstract Background: Dental caries remains a major public health issue worldwide, particularly among children. Pit and fissure sealants represent a high-quality, evidence-based preventive measure.
- Conditions
- Dental Caries, Prevention, Education
- Trial name
- TESS (NCT07232797)
- Testing
- tele-demonstration, traditional demonstration group
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Caries, Dental
Remineralization Effects of Hydroxyapatite Toothpaste
The objective of this in situ clinical study is to determine whether a toothpaste containing hydroxyapatite microclusters is as effective as a fluoridated kid's toothpaste in promoting remineralization of early caries lesions and…
- Trial name
- NCT03681340
- Testing
- Hydroxyapatite toothpaste, Fluoridated toothpaste
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Dr. Joachim Enax
Dental Caries Prevention
Silver Nanoparticle vs Chlorhexidine Mouthwashes for Reducing Streptococcus Mutans and Improving Salivary pH in Children
Dental caries remains one of the most common chronic diseases in children, with Streptococcus mutans playing a major role in its development.
- Trial name
- SMILE (NCT07728409)
- Testing
- Silver nanoparticle mouthwash (10 ppm), Chlorhexidine mouthwash (0.2%)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Assiut University
Autistic Disorder, Dental Caries
Effectiveness of Sealants and Fluoride Varnish in Caries Prevention in Children With Autism Spectrum Disorders
The aim of the study is to compare application of sealants together with fluoride varnishes versus only fluoride varnishes in preventing caries lesions development in the occlusal surface of first permanent molars of children…
- Conditions
- Autistic Disorder, Dental Caries, Pit and Fissure Caries
- Trial name
- NCT05146479
- Testing
- Fluoride varnish and pit and fissure sealants onto first permanent molars
- Where
- Italy
- Volunteers
- 232 people
- Sponsor
- University of Milan
Dental Caries
Educational Intervention in Preventing Early Childhood Caries
Objective: The aim of this study is to assess the effectiveness of an oral health educative intervention in preventing early childhood caries (ECC).
- Trial name
- NCT01502566
- Testing
- Education Intervention
- Where
- Brazil
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Dental Caries
Retention Rate And Caries Prevention Of Giomer Based Sealant With And Without Pre-Treatment With Bioactive Glass Air Abrasion In Young Adults
Prevention of oral diseases is preferable to treatment and is the key method of achieving cost effectiveness for oral health improvement programs.
- Trial name
- NCT06003452
- Testing
- surface treatment with Bioactive Glass Air Abrasion
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Testing a Tooth Decay Prevention Program With Cree Mothers and Infants
Dental decay is an alarming problem in Cree children. The intervention is a behavioural counseling approach called Motivational Interviewing (MI).
- Trial name
- NCT00175318
- Testing
- Motivational Interviewing
- Where
- Canada
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Dental Decay
Effect of Therapeutic Measures in Dental Caries Reduction in Children With Primary Dentition From Medellín City
The propouse of this study is to evaluate some combined preventive measures, of easy application in children under 6 years old as education, brush teeth, fluoride free tooth paste,fluoridated tooth paste, professional cleaning…
- Trial name
- NCT00475618
- Testing
- topical fluoride varnish application., professional cleaning, No fluoride toothpaste
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- CES University
White Spot Lesions, White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Assessing the Effects of Resin Infiltration and Resin Modified Glass Ionomer on the Color Changes of White Spot Lesions in a Clinical and Laboratory Setting
The goal of this clinical trial is to assess the efficacy of "Icon® resin infiltration" and "VanishTM XT varnish" in restoring the appearance of white spot lesions WSLs in healthy children affected with anterior white spot…
- Conditions
- White Spot Lesions, White Spot Lesions [Initial Caries] on Smooth Surface of Tooth, Enamel Hypomineralization
- Trial name
- RI (NCT06696105)
- Testing
- Resin infiltration, Vanish XT varnish (resin modified glass ionomer restoration)
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Caries Extending Into Dentin, Root Caries
Root Caries Excavation with Air Water/powder Prophylaxis Device for ART Restorations
The main objective of this RCT is to compare the efficacy of a powder/water jet prophylaxis device and conventional hand excavation in excavating root surface caries, with regard to restoration survival/success in older adults.
- Trial name
- ART-AIRFLOW (NCT04822246)
- Testing
- Control: Hand instrumentation for caries excavation, Intervention 1: EMS Airflow device for caries excavation, Intervention 2: Hand excavation + EMS Airflow device for caries excavation
- Where
- Switzerland
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Murali Srinivasan, Dr. med. dent., BDS, MDS, MBA, MAS
Prevention of Dental Caries
The Influence of Preventive Regimens Containing Different Toothpastes on Caries Risk of High Risk Patients: A Randomized Clinical Trial
66 Participants will be divided into three groups according to the tested regimen (A), where (A1) represents participants will be exposed to regimen including dual zinc plus arginine based toothpaste (Colgate total), (A2)…
- Trial name
- NCT04032210
- Testing
- dual Zinc plus Arginine based toothpaste (Colgate total), Zinc based toothpaste (Crest complete), Fluoride based toothpaste (Signal)
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Evaluation of Preventive Regimens With Different Toothpastes vs Fluoride Varnish & Toothpaste in High Caries Patients
This study will be conducted in order to determine the prevention effect of caries preventive regimen using herbal toothpaste and regimen using fluoride toothpaste versus fluoride toothpaste and fluoride varnish on the caries…
- Trial name
- NCT04436913
- Testing
- Himalaya complete care toothpaste, Signal toothpaste, Signal toothpaste and fluoride varnish
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Retention and Caries Prevention of Giomer Sealant With or Without Diode Laser Pre-treatment: A Randomized Controlled Trial
This randomized controlled trial evaluates the effect of diode laser pre-treatment on the retention and caries prevention of giomer-based fissure sealants in young adults aged 17-22 years.
- Trial name
- NCT07612540
- Testing
- phosphoric acid pretreatment
- Where
- 3 sites in Egypt
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Cairo University
Early Childhood Caries (ECC)
Goal Attainment-Based Parent Education for ECC Prevention
Preventing early childhood caries (ECC) requires improving parental knowledge and behavior, as parents play a critical role in establishing oral and dental health practices during early childhood.
- Trial name
- GAT-ECC (NCT07460271)
- Testing
- Structured Parent Education
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Caries Reduction, Caries Prevention
Effect of the Consumption of Probiotics in the Reduction of Incidence of Carious Lesions in Preschool Children
Probiotics are microorganisms that when administered in adequate amounts can confer health benefits. In vitro and clinical studies support the idea that lactobacilli have protective effects on oral health.
- Trial name
- Probiotics (NCT01648075)
- Testing
- Experimental: Probiotic enriched milk
- Where
- Chile
- Volunteers
- 261 people
- Sponsor
- University of Chile
Prevention of Dental Caries
Effect of Bioactive Glass Varnish on Salivary Parameters in Children: Randomized Controlled Trial
This study is a two-arm parallel randomized controlled trial led by Principal Investigator Inas Karawia at the Faculty of Dentistry, designed to evaluate and compare the short-term (immediatly) and sustained (over 6 months)…
- Trial name
- NCT07875387
- Testing
- Bioactive glass topical varnish, Fluoride varnish
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria
Dental Caries
Longitudinal Evaluation of Minimally Invasive Protocols for Dental Caries in Brazilian Schoolchildren
This multicenter longitudinal interventional study aims to evaluate minimally invasive protocols for the prevention and control of dental caries in Brazilian schoolchildren under routine public health conditions.
- Trial name
- NCT06999005
- Testing
- Fluoride Varnish Application (Preventive Protocol), Fluoride Varnish for Active Enamel Lesions, Atraumatic Restorative Treatment (ART) Sealant
- Where
- Brazil
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho