Clinical trials: Prevention of Pregnancy
Pregnancy Complications, Pregnancy, High Risk
Active Pregnancy Against COVID-19
Historically and traditionally, the recommendations related to physical exercise during pregnancy have been based more on moral or cultural issues than on scientific evidence.
- Conditions
- Pregnancy Complications, Pregnancy, High Risk, Pregnancy Induced Hypertension, Newborn Morbidity
- Trial name
- ACPREGCOV (NCT04563065)
- Testing
- Exercise program, Healthy lifestyle advise
- Where
- 2 sites in Spain
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Preeclampsia
Early Prediction and Randomised Prevention of Preeclampsia With Low Dose Aspirin in Chinese Cohort
This study intends to adopt the method of multi-center prospective randomized controlled study. The aim of this study is to obtain localized excision values through a preeclampsia screening model established in early pregnancy…
- Trial name
- NCT04631627
- Testing
- Aspirin
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Pregnancy, Sexually Transmitted Diseases
The S.A.F.E. Study : Computer-Aided Counseling to Prevent Teen Pregnancy/Sexually Transmitted Diseases (STDs)
This is a randomized clinical trial assessing the efficacy of two types of counseling (Computer-Assisted Motivational Intervention [CAMI] versus Didactic Educational Counseling [DEC]) to see which can better reduce female…
- Trial name
- NCT00151151
- Testing
- Computer-Assisted Motivational Intervention, Didactic Educational Counseling
- Where
- United States
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pregnant and Parenting Women
Promotion of Successful Parenting
Home visitation by community health workers is a commonly utilized approach to support families and prevent child maltreatment. At times, however, more intensive intervention is needed to address familial trauma, depression, or…
- Trial name
- PROMISE (NCT03808987)
- Testing
- Child-Parent Psychotherapy (CPP), Community Health Worker (CHW) home visitation
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- University of Rochester
HIV Infections
Evaluating the Pharmacokinetics, Feasibility, Acceptability, and Safety of Oral Pre-Exposure Prophylaxis for HIV Prevention During Pregnancy and Postpartum
The purpose of this study was to evaluate the pharmacokinetics, feasibility, acceptability, and safety of a fixed-dose combination of emtricitabine and tenofovir disoproxil fumarate (FTC/TDF) as oral daily pre-exposure…
- Trial name
- NCT03386578
- Testing
- Emtricitabine/Tenofovir Disoproxil Fumarate (FTC/TDF), Behavioral HIV risk reduction package, Enhanced adherence support
- Where
- 7 sites in Malawi, South Africa and 2 more
- Volunteers
- 780 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cervical Cancer, Cervical Dysplasia
Acceptability and Efficacy of Self-sampling for Cervical Cancer Screening: A Pilot Study
In Singapore, the current cervical cancer screening uptake among women in Singapore has remained at low 50% since its introduction in 2004.
- Conditions
- Cervical Cancer, Cervical Dysplasia, Human Papillomavirus Infection
- Trial name
- NCT03813576
- Testing
- Self-collected HPV vaginal swab
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Vaginal Bleeding
Tamoxifen Versus Estradiol for Unscheduled Bleeding in Etonogestrel Implant Users, a Randomized Pilot Trial
The purpose of this research study is to evaluate the ability of medicines called tamoxifen or estradiol to prevent annoying vaginal bleeding for arm implant users.
- Trial name
- NCT04933240
- Testing
- Tamoxifen Citrate 10Mg Tab, Estradiol
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Gestational Diabetes Mellitus
Pre-pregnancy Lifestyle Intervention to Prevent the Recurrence of Gestational Diabetes in Overweight and Obese Women
The overall purpose of this study is to determine the efficacy of a pre-pregnancy lifestyle intervention to reduce the recurrence of gestational diabetes mellitus in multiethnic women with overweight or obesity.
- Trial name
- NCT02763150
- Testing
- Lifestyle intervention, Health Promotion
- Where
- 2 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Preterm Labour
N-Acetyl Cysteine for Prevention of Preterm Birth
The antioxidant effect of N-Acetyl cysteine can abort the inflammatory cascade responsible for initiation of preterm labour especially among patients with reccurent preterm birth and patients having bacterial vaginosis
- Trial name
- NAC (NCT00568113)
- Testing
- acetylcysteine in arm 1
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cardiovascular Diseases, Hypertension
Uppsala Self-Screening of Cardiovascular Health
U-SCREEN is a randomized controlled trial evaluating whether systematic home-based multimodal screening for cardiovascular risk conditions, offered to residents in Region Uppsala turning 50, 55, 60, 65, 70 or 75 years of age, can…
- Conditions
- Cardiovascular Diseases, Hypertension, Dyslipidemias, Diabetes Mellitus
- Trial name
- U-SCREEN (NCT07614659)
- Testing
- Home-based multimodal cardiovascular screening
- Where
- Sweden
- Volunteers
- 45,000 people, healthy volunteers welcome
- Sponsor
- Johan Sundström
Cancer Prevention
Accelerating the Implementation of a Breast and Cervical Cancer Screening and HPV Vaccination Intervention
The proposed study will develop and test an implementation strategy called Salud en Mis Manos-Dissemination and Implementation Assistance (SEMM-DIA) which is an internet-accessible cross-platform that includes additional…
- Trial name
- NCT05524480
- Testing
- Salud en Mis Manos - Dissemination and Implementation Assistance, Salud en Mis Manos- Usual Implementation Practice
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Premature, Placental Transfusion
Evaluation of Placental Transfusion Techniques in Prevention of Prematurity Related Complications and Effect on Their Hematological Profile
The objective of this study is to evaluate the general course and prognosis associated with different methods of placental transfusion (Intact umbilical cord milking, cut- umbilical cord milking and delayed cord clamping) in…
- Trial name
- NCT06812507
- Testing
- intact umbilical milking, cut umbilical milking, Delayed cord clamping
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Postpartum Depression, Small for Gestational Age at Delivery
Happy Mother-Healthy Baby: An Anxiety-focused Early Prenatal Intervention
In the proposed study the investigators will develop an early prenatal preventive intervention targeting anxiety and conduct a randomized controlled trial in Pakistan to test its efficacy in reducing generalized anxiety disorder…
- Conditions
- Postpartum Depression, Small for Gestational Age at Delivery, Preterm Birth, Anxiety
- Trial name
- HMHB (NCT03880032)
- Testing
- Cognitive Behavioral Therapy Intervention for Anxiety
- Where
- Pakistan
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Development, Child, Postnatal Depression
Early Detection Neurodevelopmental Disorders of Children and Prevention of Postnatal Depression by Mobile Health App
The goal of this observational study is to confirm the impact of using this app adapted to be more specific for screening for 5 neurodevelopmental disorders and to evaluate the mothers' support program on the incidence of…
- Trial name
- NCT06301087
- Testing
- Web Application
- Where
- France
- Volunteers
- 55,618 people, healthy volunteers welcome
- Sponsor
- Weprom
Rheumatoid Arthritis, Chronic Kidney Diseases
MySlainte: Testing the Effect of Involving Partners in a CVD Prevention Community Lifestyle Program
MySláinte is a 12-week community-based, multi-disciplinary preventive and lifestyle intervention program to reduce CVD risk factors.
- Conditions
- Rheumatoid Arthritis, Chronic Kidney Diseases, Cardiovascular Risk Factor, Partner, Domestic
- Trial name
- NCT04300465
- Testing
- 10 week MySlainte Program
- Where
- Ireland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Contraceptive Behavior
Meaningful Use of Technology to Improve Health Care Delivery
While there have been major declines in teenage pregnancy around the country, Baltimore, Maryland has continued to experience increases over the last several years.
- Trial name
- DepoText (NCT01641380)
- Testing
- Text Messaging Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Anemia, Low Birth Weight
Treatment and Prevention of Severe Anemia in Pregnant Zanzibari Women
The purpose of this research is to compare the efficacy of two low-cost low intervention packages to prevent and treat severe anemia in pregnant women in Zanzibar, Tanzania.
- Conditions
- Anemia, Low Birth Weight, Neonatal Mortality
- Trial name
- NCT00148629
- Testing
- multivitamin, mebendazole
- Where
- Tanzania
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Cornell University
Hypertensive Disorders of Pregnancy
Utilization of Aspirin for Prevention of Pre-Eclampsia in Nigeria: A Explanatory Sequential Mixed Methods Study
The goal of this study is to evaluate the use of aspirin for the prevention of preeclampsia among moderate -to- high-risk pregnant women in tertiary care hospitals in Nigeria followed by a qualitative study to evaluate the…
- Trial name
- NCT06053203
- Testing
- Exposure of interest - Moderate or High-risk Preeclampsia
- Where
- 4 sites in Nigeria
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Premature Birth
Cerclage On LOw Risk Singletons: Cervical Cerclage for Prevention of Spontaneous Preterm Birth in Low Risk Singleton Pregnancies With Short Cervix
The aim of this study is to evaluate the efficacy of cervical cerclage in prevention of spontaneous preterm birth in singleton pregnancies with a short transvaginal cervical length (<=25mm) and without prior spontaneous preterm…
- Trial name
- COLORS (NCT03251729)
- Testing
- Cervical cerclage, Vaginal progesterone
- Where
- 3 sites in United States, Italy
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Cervical Cancer
HPV Self-sampling to Improve Access to Cervical Cancer Screening for Persons With HIV and/or Underserved Individuals
The objective of this study is to evaluate self-collection of vaginal samples for HPV testing as an alternative cervical cancer screening strategy for persons with HIV and/or limited access to care.
- Trial name
- ACCESS (NCT05528237)
- Testing
- Flocked swab paired with Roche Cobas 4800
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Washington