Clinical trials: Prevention of Weight Gain
Weight-Gain Prevention
A Two-Week Study of the Efficacy and Safety of Mifepristone in the Prevention of Olanzapine-Induced Weight Gain
This is a two-week study testing the efficacy and safety of mifepristone in the prevention of olanzapine-induced weight gain in healthy male volunteers by measuring changes in body weight and BMI.
- Trial name
- NCT00455442
- Testing
- Mifepristone
- Where
- India
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Corcept Therapeutics
Schizophrenia
Melatonin for Prevention of Metabolic Side Effects of Olanzapine
The purpose of this study is to determine whether melatonin can prevent metabolic side effects of olanzapine such as weight gain, elevated glucose concentrations and lipid abnormalities.
- Trial name
- NCT01593774
- Testing
- Melatonin
- Where
- Iran
- Volunteers
- 36 people
- Sponsor
- Guilan University of Medical Sciences
Pregnant Women
Optimizing Gestational Weight Gain for Prevention of Gestational Diabetes Mellitus in Malaysia
Gestational weight gain (GWG) has been closely related to health outcomes, particularly in gestational diabetes mellitus (GDM). Pregnant women may be particularly motivated to make healthy lifestyle changes.
- Trial name
- NCT05489536
- Testing
- A web/smartphone-based lifestyle program package
- Where
- 9 sites in Malaysia
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Schizophreniform Disorder, Bipolar I Disorder
Prevention of Weight Gain in Early Psychoses
The purpose of this study is to determine whether individuals with psychotic spectrum disorders ( Schizophrenia, Schizoaffective disorder,Schizophreniform Disorder, Bipolar Disorder (Type I),Bipolar Disorder (Type II),Major…
- Conditions
- Schizophreniform Disorder, Bipolar I Disorder, Bipolar II Disorder, Major Depressive Disorder
- Trial name
- NCT01075295
- Testing
- Behavioural Intervention for the Prevention of Weight Gain, TAU
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Centre for Addiction and Mental Health
Schizophrenia, Schizoaffective Disorders
Assessment of Safety and Efficacy of Therapy for the Prevention of Weight Gain Associated With Olanzapine
The goal of this study is to answer the following questions: Whether treatment with amantadine, metformin or zonisamide can prevent or reverse the weight gain that is associated with olanzapine Whether taking amantadine…
- Trial name
- NCT00401973
- Testing
- olanzapine, amantadine, metformin
- Where
- 15 sites in United States, Brazil and 5 more
- Volunteers
- 199 people
- Sponsor
- Eli Lilly and Company
Weight Loss
Effect of Exercise on Prevention of Weight Gain
The purpose of this study is to examine the dose-response of exercise on prevention of weight gain in overweight adults.
- Trial name
- NCT00177502
- Testing
- behavioral exercise intervention
- Where
- United States
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Obesity, Growth
Prevention of Overweight in Infancy
Obesity is one of the biggest threats to health in the 21st century. Rapid weight gain in the first year of life tends to lead to overweight in children, which in turn leads to overweight in adults.
- Conditions
- Obesity, Growth, Sleep
- Trial name
- POInz (NCT00892983)
- Testing
- FAB, Sleep
- Where
- New Zealand
- Volunteers
- 802 people, healthy volunteers welcome
- Sponsor
- University of Otago
Healthy Volunteers
Weight Gain Prevention in Adolescents and Young Adults
The investigators believe they key to effective prevention of obesity is early identification of individuals at high risk of excess weight gain and proactive implementation of a comprehensive approach including lifestyle-based…
- Trial name
- NCT06905626
- Testing
- Qsymia 7.5 miligrams (mg)-46 mg Extended Release Capsule
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Body Weight Changes
Evaluate the Effects of Repeated Periods of Modified Fasting to Support Healthy Natural Weight Management and Prevention of Weight Gain
The purpose of this study is to assess the effects of repeated periods of modified fasting in support of healthy weight management and prevention of weight gain over the winter holiday period (mid-November to early January) in…
- Trial name
- NCT03372109
- Testing
- Meal replacement shake, Multivitamin and mineral capsules, Fish oil with sesame lignans and olive extract softgel
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.
Weight Gain, Obesity
Prevention of Weight Gain in Young Adults
The purpose of the present study is to determine whether weight gain may be prevented by a small group seminar-based two-year educational intervention on healthy lifestyle in freshmen at the Faculté de médecine de l'Université de…
- Conditions
- Weight Gain, Obesity, Overweight
- Trial name
- NCT00306449
- Testing
- Small group seminar-based educational intervention
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Prostatic Neoplasm
Prevention of Metabolic Syndrome and Increased Weight Using Metformin Concurrent to Androgen Deprivation Therapy and Radiotherapy for Locally Advanced Adenocarcinoma of the Prostate
In current clinical practice, an acceptable standard treatment for locally advanced prostate cancer is radiation therapy in combination with hormone therapy (called Treatment B or Group B in this study).
- Trial name
- PREMIUM (NCT01996696)
- Testing
- Metformin
- Where
- 3 sites in Canada
- Volunteers
- 83 people
- Sponsor
- AHS Cancer Control Alberta
Body Weight Changes, Breast Neoplasms
The Use of Smart Scales for Weight Gain Prevention in African American Breast Cancer Survivors
The purpose of this study is to test the feasibility of two 6-month behavioral interventions for weight gain prevention (self-regulation plus activity monitoring or self-regulation) among African American breast cancer survivors…
- Trial name
- NCT02030353
- Testing
- Self-regulation plus activity monitoring, Self-regulation
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Obesity
Prevention of Postpartum Weight Retention in Low Income WIC Women
This study will examine the effects of an online behavioral intervention to promote weight loss in low income postpartum women in the WIC program.
- Trial name
- NCT01408147
- Testing
- Online postpartum weight control
- Where
- 2 sites in United States
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Prevention of Weight Gain
A Pilot Study of Diabetes Risk Reduction Program With WIC Mothers(The Special Supplemental Nutrition Program for Women, Infants, and Children) Overweight WIC Mothers
1) to evaluate treatment fidelity of DRRP: study design, training of interventionists, delivery and receipt of the intervention, and application of the intervention in real-life settings; 2) to identify successful strategies for…
- Trial name
- NCT00944060
- Testing
- lifestyle intervention
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Schizophenia Disorder, Schizoaffective Disorder
Exercise and Olanzapine-samidorphan
This is a single site trial in 30 patients with schizophrenia, schizoaffective, or bipolar I/II/NOS disorder in which all participants will receive eight weeks of olanzapine and samidorphan (Olz/Sam) plus four weeks of aerobic…
- Conditions
- Schizophenia Disorder, Schizoaffective Disorder, Bipolar Disorder I or II, Bipolar Disorder NOS
- Trial name
- NCT06740890
- Testing
- Olanzapine-samidorphan + exercise
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- New York State Psychiatric Institute
Prevention, Weight Gain
Prevention of Weight Gain in University Students
This study assess whether a small-group seminar intervention to prevent weight gain is effective in a general university student population, and to address the relative role of biological vs.
- Trial name
- PGP2 (NCT00995462)
- Testing
- Lifestyle intervention seminars
- Where
- Canada
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Marie-France Hivert
Weight Gain, Overweight
Evaluation of the Effect of Two Online Interventions -Watch Your Weight During the Holidays Program and the Relative 5:2 Fasting- for the Prevention of Body Weight Gain at 8 Weeks in Mexican Adults in the Covid-19 Pandemic
Introduction. Obesity is the main risk factor for the development of chronic degenerative diseases in Mexico and other countries around the world.
- Conditions
- Weight Gain, Overweight, Obesity
- Trial name
- NCT05060978
- Testing
- Watch your Weight During the Holidays Program, Relative 5:2 Fasting, Control Group
- Where
- Mexico
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad de Sonora
Obesity
Healthy Homes/Healthy Kids Preschool
The goals of this study are to evaluate the feasibility, acceptability, and potential efficacy of an innovative obesity prevention intervention integrating pediatrician counseling and a home-based program to prevent unhealthy…
- Trial name
- HHHK (NCT01080885)
- Testing
- Busy Bodies/Better Bites, Healthy Spots/Safe Tots
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- HealthPartners Institute
Overweight, Obesity
The Healthy Start Project: Primary Prevention of Overweight in Preschool Children Susceptible to Future Overweight
Obesity prevention should remain a priority, although there is some evidence of a possible leveling off in some age groups across European countries and in USA, Japan and Australia.
- Trial name
- NCT01583335
- Testing
- Lifestyle habits, including sleep and stress
- Where
- Denmark
- Volunteers
- 1,202 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Overweight and Obesity
Young, Fit and Happy. A Web-based Intervention to Prevent Obesity in Adolescents.
The prevalence of overweight and obesity is increasing throughout the world. Obesity is seen as one of the most important public health threats because of the significant impact of chronic conditions associated with obesity.
- Trial name
- YFH (NCT01700309)
- Testing
- Young and Active
- Where
- 2 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Oslo Metropolitan University