Clinical trials: Preventive Care
Respiratory Viral Infection, Common Cold
Prophylactic Treatment With Carragelose Nasal Spary to Prevent SARS-CoV-2, COVID-19, Infections in Health Care Workers
This is a prospective, randomized placebo-controlled double blinded clinical trial in frontline healthcare workers managing COVID-19 patients. Participants will be weekly tested for SARS-CoV-2 and a panel of respiratory viruses.
- Conditions
- Respiratory Viral Infection, Common Cold, Severe Acute Respiratory Syndrome (SARS) Pneumonia, COVID-19
- Trial name
- NCT04681001
- Testing
- nasal spray
- Where
- 2 sites in Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Marinomed Biotech AG
Ischemic Stroke, Hemorrhagic Stroke
Improved Prevention of Stroke in Primary Care in Stockholm, Sweden (Förbättrad Prevention av Stroke)
Stroke is a devastating disease. The acute mortality in Sweden is 20 % and 25 % of all patients relapse. Secondary prevention is proven efficient but observational studies have shown that a number of patients are lost to follow…
- Conditions
- Ischemic Stroke, Hemorrhagic Stroke, TIA, Atrial Fibrillation
- Trial name
- NCT01942031
- Testing
- structured collegial feed back
- Where
- Sweden
- Volunteers
- 204 people
- Sponsor
- Karolinska Institutet
Preconception Care
Computer-assisted Preventive Health Education for Women of Reproductive Age in Urgent Care Settings
The purpose of this study is to determine whether "video doctor" programs can effectively deliver preventive health messages to women of reproductive age while they wait to be seen in urgent care settings.
- Trial name
- NCT00177515
- Testing
- "video doctor," computer module
- Where
- United States
- Volunteers
- 446 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Preventive Care
Oral Feeding Delay Prevention in Preterm Newborns
Preventing oral feeding delays in preterm newborns remains a stake for NICU nowadays. Indeed, it lengthens hospitalization duration, distorts parent-newborns relationships, and increases the risks of adverse nursing outcomes.
- Trial name
- PARENTALIM (NCT06184386)
- Testing
- NIDCAPARENTALIM, SOFS
- Where
- France
- Volunteers
- 43 people
- Sponsor
- University Hospital, Caen
Dental Caries
CAMBRA - PBRN Caries Management By Risk Assessment In A Practice-Based Research Network
The goal of this project is to create a Practice Based Research Network with 30 researcher dentists calibrated on the administration of a caries risk assessment and the treatment modalities recommended based on the caries risk…
- Trial name
- CAMBRA-PBRN (NCT01176396)
- Testing
- Caries prevention active intervention, control treatment
- Where
- United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
HIV Infections
A Study to Prepare for Future HIV Vaccine Studies
The purpose of this study is to determine the ability of HVTN sites to recruit and retain people at risk for HIV infection for possible future HIV vaccine research studies.
- Trial name
- NCT00029744
- Where
- 2 sites in Haiti, Peru
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Chronic Disease
Post Affordable Care Act Evaluation
This innovative study will measure the impact of Affordable Care Act-sponsored Medicaid expansions on access to and utilization of community health center (CHC) services.
- Trial name
- PACE (NCT02657499)
- Testing
- Medicaid Expansion
- Where
- United States
- Volunteers
- 1,939,848 people
- Sponsor
- Oregon Health and Science University
COVID-19
Early Prophylactic Low-molecular-weight Heparin (LMWH) in Symptomatic COVID-19 Positive Patients
Evidence has shown that COVID-19 infections can lead to an increased risk of blood clots. These blood clots can lead to individuals being admitted to hospital, or, unfortunately in severe cases, death.
- Trial name
- ETHIC (NCT04492254)
- Testing
- Enoxaparin
- Where
- 3 sites in Australia, Belgium and 1 more
- Volunteers
- 219 people
- Sponsor
- Thrombosis Research Institute
Acute Respiratory Tract Infections, Respiratory Infection Prevention
Effectiveness of Education on Preventive Measures Against Acute Respiratory Tract Infections in School-Age Children
This study aimed to evaluate the effectiveness of an animation video-supported education program on preventive measures against acute respiratory tract infections among first-grade primary school children.
- Conditions
- Acute Respiratory Tract Infections, Respiratory Infection Prevention, Hand Hygiene, Respiratory Hygiene
- Trial name
- NCT07654712
- Testing
- Animation Video-Supported Education on Preventive Measures Against Acute Respiratory Tract Infections
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Atherosclerosis
Long-term Impact Evaluation of a Worksite-based Lifestyle Intervention to Reduce Cardiovascular Risk in Office Workers
The main objective of TANSNIP-PESA is to determine in a population of asymptomatic bank employees with high and low imaging defined cardiovascular disease (CVD) risk the effectiveness of a comprehensive 3-year worksite-based…
- Trial name
- TANSNIP-PESA (NCT02561065)
- Testing
- Lifestyle intervention
- Volunteers
- 1,020 people, healthy volunteers welcome
- Sponsor
- Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III
Central Nervous System Diseases
Dexmedetomidine in Patients After Intracranial Surgery
Dexmedetomidine is a highly selective a2-adrenoreceptor agonist that produces dose-dependent sedation and analgesia without respiratory depression.
- Trial name
- NCT01445639
- Testing
- Dexmedetomidine, Normal saline
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Capital Medical University
Asthma
School-Based Preventive Asthma Care Technology: A Trial Using a Novel Technology to Improve Adherence
The goal of this new translational project is to test the feasibility and effectiveness of implementing school-based directly observed therapy of preventive asthma medications in a real-world setting, using state-of-the-art…
- Trial name
- SB-PACT (NCT01175434)
- Testing
- School-Based Medication Delivery
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Rochester
Food Insecurity Among Children, Food Insecurity in Post Partum Women
Nurturing Care Family Navigator
The goal of this pilot randomized controlled trial is to determine whether a 6-month behavioral health intervention with a Nurturing Care Family Navigator (NCFN) improves levels of food security among postpartum low-income…
- Conditions
- Food Insecurity Among Children, Food Insecurity in Post Partum Women, Care Coordination in Primary Care, Preventive Care / Anticipatory Guidance
- Trial name
- NCFN (NCT06859372)
- Testing
- Nurturing Care Family Navigator
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Nevada, Las Vegas
Pediatric Cancer, Cancer Survivor
LOG-I - Impact Study of LOG-AFTER Software on Long-term Monitoring of Former Patients (LOG-I - LOG-Impact Study)
Childhood cancer survivors represent a high-risk population that requires risk-based follow-up. Follow-up recommendations have been harmonized.
- Conditions
- Pediatric Cancer, Cancer Survivor, Hemato-oncologic Patients
- Trial name
- LOG-I (NCT06939322)
- Testing
- Use of the Log-AFTER software
- Where
- France
- Volunteers
- 320 people
- Sponsor
- University Hospital, Angers
Graft-versus-Host Disease
Lenalidomide (Revlimid®) as Second Line Therapy in Patients With Chronic Graft-Vs-Host Disease (GVHD)
The goal of this clinical research study is to learn if Revlimid® (lenalidomide), along with standard-of-care steroid treatment you are already receiving, can help to control Chronic Graft-Versus-Host Disease (cGVHD).
- Trial name
- NCT00675441
- Testing
- Lenalidomide
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- M.D. Anderson Cancer Center
Postoperative Nausea and Vomiting
Prophylactic Ondansetron in Post-op Cardiac Surgery Patients to Prevent Post-operative Nausea and Vomiting
To evaluate the effectiveness of a prophylactic dose of ondansetron in decreasing the incidence of post-operative nausea and vomiting in cardiac surgery patients after cessation of post-operative sedation.
- Trial name
- NCT02966041
- Testing
- Ondansetron, Saline
- Where
- Canada
- Volunteers
- 186 people
- Sponsor
- University of British Columbia
Stroke, Transient Ischemic Attack
Preventing Recurrent Stroke in Minority Populations
This study focuses on causes of under-use of secondary stroke preventive measures demonstrated in randomized clinical trials to be efficacious, but not appropriately utilized in urban, minority populations.
- Trial name
- NCT00211731
- Testing
- Chronic Disease Self Management Course
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Patient-centered Care
Impact of a Wellness Portal on The Delivery of Patient-Centered Preventive Care
Building upon our experience with a very sophisticated preventive services prompt and reminder system, the Preventive Services Reminder System (PSRS), the investigators propose to conduct a systematic three-year study with the…
- Trial name
- NCT01520662
- Testing
- Implementation of a secure web-based patient Wellness Portal
- Where
- United States
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Cardiovascular Disease, Alcohol Use Disorder
Mortality Reductions Based on AUD/Heavy Alcohol Use, HIV Risk, and Cardiovascular Risk
The purpose of this research study is to investigate if a personalized intervention including parts such as navigation (focus on patient outreach efforts, missed and completed encounters), personalization (individual health…
- Conditions
- Cardiovascular Disease, Alcohol Use Disorder, HIV Risk, Substance Use Disorders
- Trial name
- NCT05828849
- Testing
- Navigation, compensation, and personalization
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Obesity, Ventilation
Non-invasive Ventilation Following Extubation (Prophylactic) to Prevent Extubation Failure in Critically Obese Patients
Mechanical ventilation is the first artificial support used in intensive care. After a period of invasive mechanical ventilation, patients should be separated from the ventilator (weaning period of mechanical ventilation).
- Conditions
- Obesity, Ventilation, Intensive Care Unit
- Trial name
- EXTUB-OBESE (NCT04014920)
- Testing
- Oxygen group, NIV Group
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Montpellier