Clinical trials: Preventive Care
Scleroderma, Systemic Sclerosis
Preventive Effect of Clopidogrel on the Systemic Sclerosis Development Risk
Systemic sclerosis (SSc) is a severe autoimmune disease associating dysimmunity, vasculopathy and fibrosis. No curative treatment is available. Pre-clinical abnormalities can be found such as specific autoantibodies.
- Trial name
- PSSIT (NCT05098704)
- Testing
- clopidogrel treatment
- Where
- 11 sites in France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Bordeaux
Microbiota-related Disease, Oral Hygiene
Interdental Hygiene Methods in Young Adults
Oral health is essential for overall well-being and systemic health. A key factor in preserving this health is maintaining the balance of the interdental microbiota, which involves regulating the quantity of pathogenic bacteria…
- Conditions
- Microbiota-related Disease, Oral Hygiene, Periodontal Diseases
- Trial name
- HIJA (NCT06848790)
- Testing
- Calibrated interdental brush
- Where
- France
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Diaper Dermatitis, Urinary Tract Infections
Intervention to Reduce Diaper Need and Increase Use of Pediatric Preventive Care
Well-child care is the primary source of preventative health care for children. These visits provide an opportunity for physicians to assess an infant's biomedical health, development, and behavior, as well as help ensure timely…
- Conditions
- Diaper Dermatitis, Urinary Tract Infections, Infection, Depressive Symptoms
- Trial name
- NCT03490045
- Testing
- Diaper Incentive, Conditional Cash Transfer Condition
- Where
- 2 sites in United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Yale University
HIV, Tuberculosis
ENhance Initiation and Retention in Isoniazid Preventive Therapy (IPT) Care for HIV Study (ENRICH Study)
The purpose of the ENRICH study is to evaluate a combination intervention package (CIP) designed to improve implementation of Isoniazid Preventive Therapy (IPT) among people living with HIV (PLWH) in Ethiopia.
- Trial name
- ENRICH (NCT01926379)
- Testing
- Combination intervention components, Isoniazid Prevention Therapy
- Where
- 10 sites in Ethiopia
- Volunteers
- 338 people
- Sponsor
- Columbia University
Compliance
A Feasibility Study for the One-dose Clinical Trial (1DT)
This feasibility study was developed to evaluate the proposed approaches for enrollment, sample collection, interview and retention over a six-month vaccination period for the clinical trial: "A scientific evaluation of one and…
- Trial name
- FS-ESCUDDO (NCT02799732)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Fundación Inciensa
Ambulatory Care Information Systems, Clinical Decision Support Systems
Improving Safety and Quality With Outpatient Order Entry
The purpose of this study is to evaluate the impact of integrating ambulatory computerized physician order entry (ACPOE) and advanced clinical decision support systems (CDSS) on safety and quality domains in the ambulatory…
- Trial name
- NCT00243334
- Testing
- Integration of advanced clinical decision support with ambulatory computerized physician order entry
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Brigham and Women's Hospital
Craniotomy Surgery, Preventive Health Care
The Effect of Bundle Application on Surgical Site Infection
Surgical site infections (SSI) are the most common complications after surgical operations and are in the top three in Healthcare Associated Infections (HIE).
- Trial name
- NCT06724354
- Testing
- The Surgical Site Infections Precaution Package Form includes the parameters that should be applied to patients before, during and after surgery.
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Periodontitis
Periodontal Disease Prevention Study
This study is one component of a program to improve the maintenance of good dental health and the prevention of disease by use of risk stratification methods to efficiently guide increased preventive services to adult dental…
- Trial name
- NCT01584479
- Where
- United States
- Volunteers
- 5,117 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Respiratory Distress Syndrome, Newborn
Observational Study on the Prophylactic Use of Curosurf in Neonatal Respiratory Distress Syndrome (RDS)
The aim of Alizé is to describe a population of premature babies (gestational age (GA) < 32 weeks) in real life situation and the management of RDS.
- Trial name
- NCT01102543
- Where
- France
- Volunteers
- 972 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Hypertension
Mobilizing Community Hypertension Access Pilot
The Live Healthy Chicago (LHC) Community Pilot is a prospective, community-based study evaluating the feasibility, effectiveness, and economic impact of a pharmacist-led hypertension management program delivered in trusted…
- Trial name
- NCT07547345
- Testing
- Community-Based Multidisciplinary Hypertension Management Program
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Rush University Medical Center
Cervical Cancer, Human Papillomavirus Infection
Effect of Health Belief Model-Based Education on Cervical Cancer Knowledge and HPV Vaccine Attitudes in Women
This study evaluated the effect of a Health Belief Model-based educational intervention on women's knowledge of cervical cancer and their attitudes and beliefs toward HPV vaccination.
- Conditions
- Cervical Cancer, Human Papillomavirus Infection, Preventive Health Services
- Trial name
- HBM-HPV (NCT07521163)
- Testing
- Health Belief Model-Based Education
- Where
- Turkey (Türkiye)
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Muhammet Faruk Yigit
Cardiac Arrest, Ventricular Arrythmia
Prophylactic Amiodarone for Shockable Cardiac Arrest
The aim of this study is to determine whether the prophylactic amiodarone can prevent re-arrest with ventricular shockable rhythm in patients who treated with targeted temperature management after return of spontaneous…
- Trial name
- NCT04845607
- Testing
- Amiodarone Injection
- Where
- South Korea
- Volunteers
- 302 people
- Sponsor
- Won Young Kim
Migraine
Comparison of the Effectiveness of First-line Preventive Treatment of Migraine in Primary Care
This study, which is aimed at comparing the effectiveness of the most frequently used drugs in the first line in primary care for the preventive treatment of migraine (amitriptyline, flunarizine, topiramate and propranolol), is a…
- Trial name
- PREMI (NCT06499116)
- Testing
- Topiramate, Flunarizine, Amitriptyline
- Volunteers
- 460 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Vulvar Health, Vulvar Self-Examination
Health Belief Model-Based Vulvar Self-Examination Education
This randomized controlled trial was conducted to evaluate the effectiveness of a Health Belief Model-based Vulvar Self-Examination (VSE) education program on women's health beliefs, vulvar health awareness, and vulvar…
- Conditions
- Vulvar Health, Vulvar Self-Examination, Women's Health, Health Belief Model
- Trial name
- NCT07621315
- Testing
- Self-Examination of the Vulva Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Lifestyle-Related Disorder
An Adjusted Preventive Program Against Lifestyle Related Diseases
A large proportion of the Danish population leads an unhealthy lifestyle. The associated surge in lifestyle-related disease (LRD) represents a significant health and economic burden for the individual as well as society.
- Trial name
- TOFpilot2 (NCT03913585)
- Testing
- Lifestyle intervention
- Where
- 4 sites in Denmark
- Volunteers
- 4,800 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Preventive Health Services
Increasing the Feasibility, Impact, and Equity of the Medicare Annual Wellness Visit (AWV)
The goal of this study is to improve the use of preventive health services by implementing a multilevel intervention to stimulate Annual Wellness Visit use in diverse practices across the United States.
- Trial name
- NCT05910736
- Testing
- Medicare AWV Practice Redesign Toolkit
- Where
- 3 sites in United States
- Volunteers
- 22,485 people
- Sponsor
- University of California, Los Angeles
Depression, Postpartum, Anxiety
Implementation of a Psychoeducational Intervention in New Mothers
The goal of this clinical trial is to implement and examine the clinical effectiveness in a randomized study of the Catalan and Spanish versions of the culturally adapted "What Were We Thinking (WWWT)" psychoeducational…
- Trial name
- EQEP (NCT06512025)
- Testing
- WWWT psychoeducative intervention
- Where
- 2 sites in Spain
- Volunteers
- 400 people
- Sponsor
- Alba Roca
Health Services Accessibility, Rural Health
Health Ahead Comparative Effectiveness Study
The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening on the path toward a fully automated screening…
- Conditions
- Health Services Accessibility, Rural Health, Medically Underserved Area, Preventive Health Services
- Trial name
- HACE (NCT07669168)
- Testing
- AI-Assisted Screening Interpretation (AI Reads), Human-Only Screening Interpretation
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- William Brandenburg, MD
Preventive Medicine, Hypertension
ThumpThump Pilot Study
Brain disease and heart disease are the leading causes of death and disability in the US; at least 60% of cases can be attributed to modifiable risk factors such as hypertension, dyslipidemia, and poor-quality diet.
- Trial name
- ThumpThump (NCT07865247)
- Testing
- : Implementation strategy to improve hypertension care in geopolitically defined communities
- Where
- United States
- Volunteers
- 3,680 people, healthy volunteers welcome
- Sponsor
- Yale University
Well Child Preventive Care
Can Parental Activation Over the Internet Improve Pediatric Preventive Care?
This study is a randomized controlled trial of an evidence based, patient specific web site's ability to improve preventive practices in pediatric care.
- Trial name
- NCT00101855
- Testing
- An evidence based tailored web site
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)