Clinical trials: Preventive Intervention
Surgical Site Infection, Surgical Wound Infection
Floraseal Versus Iodine Impregnated Adhesive Drapes
Infection after total joint arthroplasty can have devastating consequences. Adhesive drapes have been traditionally used at our institution to help reduce the risk of wound contamination and infection by superficial skin flora.
- Trial name
- NCT03466489
- Testing
- Floraseal
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Malaria (Plasmodium Falciparum), Malaria Incidence
Insecticide-Treated Baby Wraps for the Prevention of Malaria
The objective is to test the protective effect of permethrin-treated and etofenprox-treated lesus against malaria in young children
- Trial name
- NCT07773350
- Testing
- Permethrin-treated lesu, Etofenprox-treated lesu, Untreated lesu
- Where
- Uganda
- Volunteers
- 1,296 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Caries,Dental
Fluoride Caries-control Effectiveness/Feasibility in Children
The aim of this study is to compare the effectiveness and feasibility of using silver diamine fluoride solution (SDF) vs. sodium fluoride varnish (NaF) for caries management in children from Bogotá (and its suburban areas) and…
- Trial name
- NCT06690008
- Testing
- Experimental group
- Where
- 2 sites in Colombia
- Volunteers
- 814 people, healthy volunteers welcome
- Sponsor
- Universidad El Bosque, Bogotá
Abuse Neglect Social, Deprivation, Maltreatment Syndrome (Infant or Child)
Nursing Led Interdisciplinary Intervention in Prevention of Girl Child Mortality and Maltreatment
In Northern India, skewed sex ratios, female feticide and higher child mortality rates for girls have become serious concern. The female child mortality as a result of son preference have increased during the last several…
- Trial name
- NCT02279368
- Testing
- Family Counselling and safeguarding
- Where
- 3 sites in India
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Adwin Life Care
HIV Prevention
Safety and Acceptability Study of PrePex Device When Removing the Foreskin Shortly After Placement of Device
To assess the safety and acceptability of the non-surgical PrePex device among healthy adult male participants scheduled for voluntary medical male circumcision when removing the foreskin shortly after device placement.
- Trial name
- NCT03132285
- Testing
- PrePex
- Where
- 2 sites in Zambia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Zambia
Influenza
Safety and Immunogenicity of Two Doses of a Tetravalent Influenza Vaccine in Adults Aged 18 Years and Above
Evaluate the immune response and reactogenicity of H5N1 vaccination in adults aged 18 years and above (as part of a tetravalent vaccine)
- Trial name
- NCT00620815
- Testing
- Pandemic influenza vaccine + seasonal influenza vaccine /pandemic influenza vaccine, Pandemic influenza vaccine + seasonal influenza vaccine / pandemic influenza vaccine
- Where
- 2 sites in Germany
- Volunteers
- 601 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Injuries
Safety Skills Training: Parents of School-Aged Children
Injuries are the leading cause of death and disability in children in America. Most injuries can be prevented when parents implement effective child safety practices.
- Trial name
- SAS_2 (NCT02329340)
- Testing
- Am Academy of Pediatrics print materials, Family safety 1-2-3
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Oregon Center for Applied Science, Inc.
Dengue
Insecticidal School Uniforms for Dengue Prevention in Thailand
This is a randomised controlled trial that will be conducted in eastern Thailand in a group of schools with approximately 2,000 students aged 7-15 years.
- Trial name
- DengueTools (NCT01563640)
- Testing
- permethrin insecticide, washing
- Where
- Thailand
- Volunteers
- 1,825 people, healthy volunteers welcome
- Sponsor
- Umeå University
Smoking, Cigarette, Breastfeeding
Lung and Breast Cancer Prevention by an Integrated Intervention of Maternal Smoking Cessation and Breastfeeding
This pilot clinical trial aims to integrate maternal smoking cessation and breastfeeding interventions to enhance both cancer prevention behaviors.
- Trial name
- NCT05123118
- Testing
- Integrated intervention of smoking cessation and breastfeeding
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Xiaozhong Wen
Human Papilloma Virus
Prevention of Cervical Cancer Using the Genotyping Screening and Same-day Self-sampling
In May 2018, the World Health Organization (WHO) launched a strategy to eliminate cervical cancer. While this strategy seeks to achieve coverage of 70% in disease testing and 90% in treatment by 2030, it is estimated that these…
- Trial name
- PROGRESS (NCT07232355)
- Where
- 4 sites in United States, El Salvador and 1 more
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Atila Biosystems Inc.
Athletic Injuries, Sports Injury Prevention
Evaluation of Injury Risk Factors and Effects of Individualized Exercise Program in Basketball and Volleyball Athletes
This study aims to identify injury risk factors using a clinical/functional test battery in university basketball and volleyball athletes, to develop individualized exercise prescriptions for athletes scoring below established…
- Conditions
- Athletic Injuries, Sports Injury Prevention, Musculoskeletal Injury
- Trial name
- IRISPORT (NCT07521215)
- Testing
- Test-Specific Individualized Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Delirium, Bypass Complication
Care Bundle's Impact on Delirium Prevention in CABG Patients
This research investigates the effectiveness of a care package used in the care of patients undergoing coronary artery bypass graft (CABG) surgery in preventing postoperative delirium.
- Conditions
- Delirium, Bypass Complication, Coronary Artery Bypass, Patient Care Bundles
- Trial name
- CareBundle (NCT06036017)
- Testing
- Earplugs, Music Therapy, Presence of Family After Extubation:
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- İslam Elagöz
Substance Use
A Family-Centered Ojibwe Substance Abuse Prevention
This study will complete a multisite randomized controlled trial (RCT) of a family-centered alcohol and drug prevention program for Anishinabe (Ojibwe) pre-adolescents in 3rd or 4th grade (Fall 2017) or who are age 8-10 years on…
- Trial name
- BZDDD (NCT02700035)
- Testing
- Bii-Zin-Da-De-Dah (Listening to One Another)
- Volunteers
- 705 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Tobacco Smoking Behavior
Teens Against Tobacco Use: A Model for Universal Tobacco Prevention and Youth Advocacy
This study evaluates the efficacy of Teens Against Tobacco Use anti-tobacco presentations on tobacco use susceptibility in 4th-8th grade.
- Trial name
- TATU (NCT02443025)
- Testing
- Teens Against Tobacco Use
- Where
- United States
- Volunteers
- 2,414 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Accidental Falls, Fractures
Exercise Intervention to Prevent Fall-related Fractures and Other Injuries : The Ossébo Study
1. Primary objective: to evaluate the effectiveness of a fall prevention exercise program in preventing falls resulting in fractures and other physical traumas. 2.
- Conditions
- Accidental Falls, Fractures, Fall-related Injuries
- Trial name
- Ossébo (NCT00545350)
- Testing
- Fall prevention exercise program
- Where
- 20 sites in France
- Volunteers
- 706 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Plaque, Dental Plaque
Clinical Evaluation of a Toothpaste for Dental Plaque Reduction and Prevention of Gum Problems
Qualified subjects will be enrolled and randomized to either one of the three study groups described above based on their initial modified gingivitis and plaque scores.
- Conditions
- Plaque, Dental Plaque, Gingivitis
- Trial name
- NCT07842991
- Testing
- 0.45% SnF HW with NaF (1450 F), 67% Bicarbonate with NaF (1400 F), Colgate Cavity Protection Toothpaste
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Aging, Postural Balance
Tai Chi Intervention for Balance Function in Older Adults: Predictive and Modifying Roles of Circadian Age
This study investigates the effects of a 12-week Tai Chi intervention on balance function in community-dwelling older adults. Participants are randomly assigned to either a Tai Chi exercise group or a health education control…
- Conditions
- Aging, Postural Balance, Accidental Falls
- Trial name
- NCT07567976
- Testing
- Tai Chi Exercise, Health Education
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zhide Liang
Lung Cancer
Implementing Fragmentomics Into Real World Screening IntervenTions to Evaluate Clinical Utility Among Individuals With Elevated Risk for Lung Cancer
The purpose of this study is to determine whether availability of DNA Evaluation of Fragments for Early Interception (DELFI) Lung Cancer Screening Test, FirstLook™ to practicing physicians affects overall lung cancer screening…
- Trial name
- FIRSTLUNG (NCT06145750)
- Testing
- Ability to order FirstLook™, Continuing Medical Education for Lung Cancer
- Where
- 3 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Delfi Diagnostics Inc.
Substance Use, Stress
Automating Peer Learning to Reduce Alcohol Use and Related Deviant Behavior in Secondary School
Deviant peer affiliation is one of the most important predictors of alcohol use in adolescence. These affiliations arise when socially marginalized youth self-aggregate and reinforce alcohol use and other deviant activity (i.e.…
- Conditions
- Substance Use, Stress, Relation, Interpersonal, Bullying
- Trial name
- PeerLearning (NCT04478240)
- Testing
- PeerLearning.net
- Where
- United States
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Reperfusion Injury
Remote Ischaemic PreConditioning (RIPC) in Partial Nephrectomy for the Prevention of Ischemia/Reperfusion Injury
"Remote Ischaemic PreConditioning" (RIPC) is performed prior to partial nephrectomy. Postoperative calprotectin dynamics and Blood Oxygen-Level-Dependent (BOLD) MRI are used to to demonstrate the potential renoprotective effect…
- Trial name
- NCT03068689
- Testing
- RIPC
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
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