Clinical trials: Preventive Intervention
HIV, Minority Stress
Developing an Online Mindfulness-based Intervention to Reduce Minority Stress and HIV Risk Among Young Adult MSM
The overall aim of the research study is to develop and test a mindfulness-based program for young adult gay, bisexual, and queer men at risk for HIV (Brown University IRB approved protocol #2004002698).
- Conditions
- HIV, Minority Stress, Mental Health Wellness 1
- Trial name
- NCT05540652
- Testing
- Mindfulness-Based Queer Resilience (MBQR)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Brown University
HIV Prevention
The PROTECT (PrEP Optimization Through Telehealth Care and Treatment) Trial
The expansion of HIV pre-exposure prophylaxis (PrEP) care has been endorsed as a key strategy for reducing new HIV infections, however, PrEP trials among people who inject drugs (PWID) are rare and uptake of PrEP has been…
- Trial name
- PROTECT (NCT06845774)
- Testing
- CDC PrEP with active referral, TelePrEP
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hilary L Surratt, PhD
Risk Behavior, Substance Abuse
Juvenile Offender HIV Prevention and Drug Abuse Services
This study will determine the clinical effectiveness, moderators and mechanisms of change, and economic impact of an integrative, family-based intervention that concurrently targets change in HIV/Sexually Transmitted Disease…
- Conditions
- Risk Behavior, Substance Abuse, Delinquency
- Trial name
- Day Treatment (NCT01922297)
- Testing
- Day Treatment MDFT-HIV, Day Treatment SAU
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Miami
HIV
HIV Self-Testing and Long-Acting Injectables for HIV Treatment and Prevention Among Commercial Minibus Drivers (I-TEST LAIs) in Nigeria
Long-acting injectable antiretroviral therapy (LAI ART) and Pre-Exposure Prophylaxis (LAI PrEP) have the potential to transform HIV treatment and prevention, especially in reaching individuals such as commercial minibus drivers…
- Trial name
- ITEST-LAI (NCT07000513)
- Testing
- ITEST-LAI
- Where
- Nigeria
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- George Washington University
Vaping Behaviors
Does the 'CATCH My Breath' Vaping Prevention Program Prevent High School Students in Ontario, Canada From Starting to Vape?
Vapes (also called e-cigarettes) have increased in popularity among youth in Canada and the United States. Youth who try vaping are at risk of becoming addicted and continuing to vape.
- Trial name
- NCT06825338
- Testing
- CATCH My Breath
- Where
- 8 sites in Canada
- Volunteers
- 5,600 people, healthy volunteers welcome
- Sponsor
- University of Ontario Institute of Technology
HIV Prevention
Reducing Intersectional Stigma Among High-Risk Women in Brazil to Promote Uptake of HIV Testing and PrEP
This is a randomized controlled trial of a multi-level intervention to prevent HIV acquisition among transgender women (N=400) in São Paulo, Brazil.
- Trial name
- PRISM Brazil (NCT04114955)
- Testing
- Manas por Manas
- Where
- 2 sites in Brazil
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Postoperative Nausea and Vomiting, Scoliosis
A Comparison Between Palonosetron Versus Granisetron as PONV Prophylaxis in Scoliotic Patients Undergoing Spine Surgery
The aim of this clinical trial is to compare the effectiveness of two Serotonin (5- HT3) receptor antagonist, palonosetron and granisetron, administered along with dexamethasone as a preventive measure against early and delayed…
- Trial name
- PONV (NCT06540885)
- Testing
- Palonosetron (Group P), Granisetron (Group G)
- Where
- 2 sites in Malaysia
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Overuse Injuries
Overuse Injuries in Road Cyclists, Prevalence and Prevention
The purpose of this study is to investigate the prevalence of overload injuries to road cyclists in Sweden, and if it 's possible to prevent low back pain by a simple exercise program for two months of training .
- Trial name
- Cycle (NCT02106715)
- Testing
- Training
- Where
- Sweden
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
COVID-19
Safety of an Inactivated SARS-CoV-2 Vaccine for Prevention of COVID-19 in Children and Adolescents
This study is a multi-center and open design, phase Ⅳ clinical trial of an inactivated SARS-CoV-2 vaccine (CoronaVac) manufactured by Sinovac Research and Development Co., Ltd.The purpose of this study is to evaluate the safety…
- Trial name
- NCT04992208
- Testing
- Experimental Group
- Where
- China
- Volunteers
- 31,041 people, healthy volunteers welcome
- Sponsor
- Sinovac Life Sciences Co., Ltd.
Behavior Problem, Social Skills
Inclusive Positive Behaviour Supports
Background: While positive school climate is important for students' well-being and mental health, school personnel may experience challenges in creating a nurturing school climate.
- Trial name
- IBIS (NCT06270914)
- Testing
- Inclusive Positive Behavior Interventions and Supports
- Where
- Sweden
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Dental Caries
Retention Rate And Caries Prevention Of Giomer Based Sealant With And Without Pre-Treatment With Bioactive Glass Air Abrasion In Young Adults
Prevention of oral diseases is preferable to treatment and is the key method of achieving cost effectiveness for oral health improvement programs.
- Trial name
- NCT06003452
- Testing
- surface treatment with Bioactive Glass Air Abrasion
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gestational Diabetes
Prevention of Gestational Diabetes Through Lifestyle Modification
OVERALL OBJECTIVES: 1. To assess the efficacy of a diet and exercise intervention before and/or during pregnancy in the prevention of GDM and its fetal complications in women with high diabetes risk. 2.
- Trial name
- RADIEL (NCT01698385)
- Testing
- Diet and exercise counseling
- Where
- Finland
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Cervical Cancer, Cervical Dysplasia
Acceptability and Efficacy of Self-sampling for Cervical Cancer Screening: A Pilot Study
In Singapore, the current cervical cancer screening uptake among women in Singapore has remained at low 50% since its introduction in 2004.
- Conditions
- Cervical Cancer, Cervical Dysplasia, Human Papillomavirus Infection
- Trial name
- NCT03813576
- Testing
- Self-collected HPV vaginal swab
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Alzheimer's Dementia
European Prevention of Alzheimer's Dementia (EPAD) Longitudinal Cohort Study (LCS)
Brain changes associated with Alzheimer's disease may precede symptoms of Alzheimer's Dementia by over 20 years. The Investigators hope to be able to identify Alzheimer's disease at its very earliest stages when in theory…
- Trial name
- EPAD-LCS (NCT02804789)
- Where
- 30 sites in Belgium, France and 7 more
- Volunteers
- 2,095 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Intimate Partner Violence
Effect of Couple Based Violence Prevention Education on Intimate Partner Violence During Pregnancy in Southern, Ethiopia
A significant proportion of women in Ethiopia suffer from violence by their intimate partner during pregnancy(IPVp), which has adverse maternal and newborn outcomes.
- Trial name
- NCT05856214
- Testing
- Couple-Based Violence Prevention education(CBVPE)
- Where
- Ethiopia
- Volunteers
- 852 people, healthy volunteers welcome
- Sponsor
- Jimma University
HIV Infections, HSV-2 Genital Herpes
Retention and Duration of Activity of SPL7013 (VivaGel®) After Vaginal Dosing.
To assess the retention and anti-viral activity (human immunodeficiency virus (HIV) and herpes simplex virus 2 (genital herpes, HSV-2) of SPL7013 in cervicovaginal samples taken up to 24 hours after administration of 3% SPL7013…
- Trial name
- NCT00740584
- Testing
- 3% SPL7013 Gel (VivaGel)
- Where
- Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Starpharma Pty Ltd
Fall Patients
Keep Exercising & Stay Steady: Development and Feasibility of a Health Intervention to Encourage Exercise Maintenance After Fall Prevention Exercise Programmes End.
Falls and broken bones are a common health problem faced by older adults. Worldwide, one third of adults aged over 65 years old, and half of adults aged over 80 years, fall each year.
- Trial name
- KESS (NCT06447948)
- Testing
- Keep Exercising and Stay Steady
- Where
- 4 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Coronary Heart Disease
Family Heart Health Program: Randomized, Controlled Trial
Background: Family members (spouses, siblings, offspring) of patients with coronary heart disease (CHD) may themselves be at increased risk for developing CHD for genetic, biochemical and/or behavioural reasons.
- Trial name
- FHHP-RCT (NCT00552591)
- Testing
- 12-week risk reduction program, managed by a Heart Health Educator
- Where
- Canada
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
HIV Infections
Affect Management for Early Adolescents
Adolescents are at risk for HIV because of sexual and drug use behavior initiated during early adolescence, and those with mental health problems appear to be particularly susceptible.
- Trial name
- NCT01197404
- Testing
- Affect Management, General Health Promotion
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Athletic Injuries, Soccer Injury
FIFA 11+ Warm-Up and Injury Risk Classification in Youth Amateur Soccer Players
This randomized controlled trial evaluated whether an eight-week, supervised FIFA 11+ neuromuscular warm-up program improves multifactorial injury risk classification, functional performance, and time-loss injury incidence in…
- Conditions
- Athletic Injuries, Soccer Injury, Lower Extremity Injury, Sprains and Strains
- Trial name
- NCT07713004
- Testing
- FIFA 11+ Neuromuscular Warm-Up Program, Routine Warm-Up
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.