Clinical trials: Preventive Intervention
Aggression, Post Traumatic Stress Disorders
Strength at Home Couples Program (PTSD-Focused Relationship Enhancement Therapy for Returning Veterans)
The purpose of the project is to develop and test a couples-based relationship enhancement group intervention for married or partnered Operation Enduring Freedom (OEF)/Operation Iraqi Freedom (OIF)/Operation New Dawn (OND)…
- Trial name
- NCT00827879
- Testing
- Strength at Home Couples Group, Supportive Group Therapy
- Where
- 2 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Boston VA Research Institute, Inc.
Falls
Promoting Physical Activity in the Over 65s
The aim of the project is to evaluate the delivery, impact and cost effectiveness of a community based exercise programme (FaME); compared to a home based exercise programme (OEP) supported by similarly aged mentors; compared…
- Trial name
- ProAct65+ (NCT00726531)
- Testing
- Otago Exercise Programme, Fame, Treatment As Usual
- Where
- 2 sites in United Kingdom
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University College, London
Antibiotic Prophylaxis
Use of Prophylactic Antibiotics Prior to OnabotulinumtoxinA
This study aims to show that lack of antibiotic prophylaxis to those undergoing bladder Botox injections is not significantly inferior to administering prophylaxis.
- Trial name
- NCT05519072
- Testing
- Nitrofurantoin
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Tobacco Prevention
Effectiveness of Comics to Promote Tobacco-related Knowledge, Attitudes and Behaviours Among Primary School Students
The goal of this pilot RCT is to evaluate the effectiveness of comics containing tobacco-related content in improving tobacco-related knowledge and attitudes among Hong Kong primary school students.
- Trial name
- NCT07453745
- Testing
- Tobacco-related comics, Conventional health leaflet
- Where
- Hong Kong
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Influenza, Virus Diseases
Safety of and Immune Response to a Bird Flu Virus Vaccine (H5N1) in Healthy Adults
Avian influenza (AI), or bird flu, has recently become a major health concern in Asia and other parts of the world. The need for a vaccine to prevent the spread of AI among livestock and to humans is sorely needed.
- Trial name
- NCT00347672
- Testing
- H5N1 (6-2) AA ca Recombinant (A/VietNam/1203/2004 x A/AnnArbor/6/60/ca)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Rabies
Safety and Immunogenicity (Non-inferiority) of a Purified Chick Embryo Cell Vaccine Vaccine Administered in Two Different Schedules (Conventional Versus Abbreviated Schedule)
This study investigates the safety and immunogenicity (non-inferiority) of a Purified Chick Embryo Cell Vaccine (PCECV) administered in two different schedules (conventional versus abbreviated schedule) in healthy adults 18 to 50…
- Trial name
- NCT00825305
- Testing
- Abbreviated Zagreb 2-1-1 schedule, Standard Essen 1-1-1-1-1 schedule
- Where
- China
- Volunteers
- 825 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Dental Caries and Streptococcus Mutans Count
Impact of Maternal Xylitol Consumption on Mutans Sterptococci
The study was designed to determine whether maternal xylitol consumption through regular chewing of xylitol gums can affect the salivary mutans streptococci (MS), dental caries, and dental plaque levels of their children.
- Trial name
- NCT02036151
- Testing
- xylitol, fluoride varnish application
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Atrial Fibrillation; Stroke Prevention
Stroke Prevention in Atrial Fibrillation Patients Between 2004 and 2020
Prevention of thromboembolic complications is an important part in the management of patients with atrial fibrillation (AF). European and American guidelines recommend the use of non-vitamin K antagonist oral anticoagulants…
- Trial name
- NCT04686045
- Testing
- observational study
- Where
- 2 sites in Poland
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Jan Kochanowski University
Noise-induced Hearing Loss
Test of a Web-based Intervention to Promote Hearing Protector Use
The purpose of this project is to compare the effectiveness of several approaches to influencing hearing protector use. The goals of this study are to further develop an intervention to promote farmers' use of hearing protectors…
- Trial name
- NCT01454895
- Testing
- Sampler of hearing protection devices, Static Web-based information, Interactive Web-based information
- Where
- United States
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- Marjorie McCullagh
Type 2 Diabetes, Men
PowerUp for Health: A Diabetes Prevention Program for Men
The purpose of this two-year proposal is to: 1. develop and 2. complete a pilot test of an adaptation of the evidence-based National Diabetes Prevention Program (NDPP) tailored to engage men with prediabetes in disadvantaged…
- Trial name
- NCT02555631
- Testing
- lifestyle
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Cardiovascular Diseases, Dementia
Senior Health Clinic Study
Turku Senior Health Clinic study The Turku Senior Health Clinic Study was targeted to 75-year-old citizens with an underlying idea that at that age it would be almost the last moment to nudge people towards healthy lifestyle and…
- Conditions
- Cardiovascular Diseases, Dementia, Frailty
- Trial name
- NCT05634239
- Testing
- Health Education
- Where
- Finland
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Turku
Tetanus, Hepatitis B
Lot-to-lot Consistency of Tritanrix™-HepB/Hib-MenAC & Its Non-inferiority vs Tritanrix™-HepB/Hiberix™ in Infants
The primary purpose of this study is to demonstrate the lot-to-lot consistency of 3 production lots of GSK Biologicals' Hib-MenAC (Haemophilus influenzae type b and meningococcal serogroups A and C) vaccine when reconstituted…
- Conditions
- Tetanus, Hepatitis B, Haemophilus Influenzae Type b, Whole Cell Pertussis
- Trial name
- NCT00197275
- Testing
- Hib-MenAC mixed with Tritanrix™-HepB
- Where
- 3 sites in Thailand
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Obesity
Prevention & Promotion in the Treatment of Obesity
Making healthy food choices requires sacrificing immediate pleasures of consuming high calorie foods in order to achieve long-term health goals.
- Trial name
- PROSPER (NCT02990494)
- Testing
- STANDARD, PREVENT, PROMOTE
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Cervical Cancer
Impact of HPV Vaccination on Prevention of Cervical HPV Infection in Sikkim, India
This project aims is to monitor the effectiveness of HPV vaccination in real-word conditions, at least 7 years after initiation of HPV vaccination in Sikkim.
- Trial name
- HPV-Vac-S (NCT04588402)
- Testing
- The study being observational in nature, there is no intervention. The investigators will only collect cervical samples from married women within a specified age range at different intervals.
- Where
- India
- Volunteers
- 5,500 people, healthy volunteers welcome
- Sponsor
- International Agency for Research on Cancer
Osteoporosis
Calcium and Bone Mass in Young Females
We originally suggested that calcium in the diet is important in determining the amount of bone (bone mass) that builds up in young adults. We are testing the effect of calcium on bone mass in 354 Caucasian (white) girls.
- Trial name
- NCT00000402
- Testing
- Calcium
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Obesity, Cardiovascular Diseases
A Clinical Trial Of Two Educational Strategies In Cardiovascular Health In Child Population
AIM: To evaluate the effectiveness of two strategies in cardiovascular risk in children 2º grade in the community of Madrid. DESIGN: cluster-randomized trial with blinded evaluator SCOPE AND SUBJECTS OF STUDY: Children of both…
- Trial name
- SAVINHEARTS (NCT01418872)
- Testing
- Didactic Concerts
- Where
- Spain
- Volunteers
- 1,730 people, healthy volunteers welcome
- Sponsor
- Agencia Lain Entralgo
Cardiovascular Diseases, Physical Inactivity
Integrating Exercise Into Lifestyle of Cardiac Outpatients
The purpose of the study is to investigate the long-term effects of a personalized physical activity program on exercise capacity and quality of life in patients with stable cardiovascular disease.
- Conditions
- Cardiovascular Diseases, Physical Inactivity, Aging, Quality of Life
- Trial name
- ITER (NCT05817305)
- Testing
- Medical history and functional evaluation, Health education
- Where
- Italy
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Ferrara
Contrast Induced Nephropathy
Oral Versus Intravenous Hydration to Prevent Contrast Induced Nephropathy
The increased risk for contrast-induced nephropathy (CIN) in patients with chronic kidney disease (CKD) undergoing coronary angiography (CAG) has been established.
- Trial name
- HYDRATE (NCT01093131)
- Testing
- Oral hydration, Oral sodium bicarbonate, Intravenous Hydration
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Western Pennsylvania Hospital
Obesity, Type 2 Diabetes
Feel4Diabetes-study
The aim of the Feel4Diabetes-study is to develop, implement and evaluate a community-based intervention aiming to create a more supportive social and physical environment to promote lifestyle and behaviour change to prevent type…
- Trial name
- Feel4Diabetes (NCT02393872)
- Testing
- Feel4Diabetes-intervention
- Where
- Greece
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- Harokopio University
HIV Infections
Effectiveness of Communication Technology in Disseminating HIV Prevention Training to Non-governmental Organizations
This study will compare the effectiveness of face-to-face training versus Web-based training seminars in disseminating HIV prevention interventions to nongovernmental organizations in Eastern Europe and Central Asia.
- Trial name
- NCT00698529
- Testing
- Face-to-face training, Distance training, Popular Opinion Leader (POL)
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
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