Clinical trials: Preventive Intervention
Tooth Hypersensitivity
NUPRO Sensodyne Prophylaxis Paste With NovaMin Sensitivity Relief Study
The study is intended to verify through clinical measurement that the NUPRO Sensodyne Prophylaxis Paste with Novamin provides immediate sensitivity relief as well as extended relief up to 28 days.
- Trial name
- NCT01669785
- Testing
- Group C, Group A, Group B
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Dentsply International
Dengue
Safety of and Immune Response to a Dengue Virus Vaccine (rDEN4delta30-4995) in Healthy Adults
Dengue fever, which is caused by dengue viruses, is a major health problem in tropical and subtropical regions of the world. The purpose of this study is to evaluate the safety and immune response to the dengue vaccine…
- Trial name
- NCT00322946
- Testing
- rDEN4delta30-4995
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
All
Family History in a Singaporean Healthy Population
The purpose of this study is to better understand the linkages between family health history (FHH) and genomics in a Singaporean population.
- Trial name
- NCT03114553
- Testing
- MeTree
- Where
- Singapore
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Prevention of Mother-to-child Transmission of HIV
Retention of Women in the PMTCT (Prevention of Mother-to-child Transmission of HIV)
EXECUTIVE SUMMARY RESEARCH QUESTION TO BE ADDRESSED BY THIS PROPOSAL What are the factors associated with retention-in-care of women enrolled in the eMTCT Option B+ program at eMTCT (elimination of mother-to-child transmission of…
- Trial name
- NCT03213223
- Where
- Zimbabwe
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- University of Zimbabwe
Glucose Intolerance, Aortic Stiffness
Healthy Aging Through Functional Food
The purpose of this study is to determine whether dietary inducers of glyoxalase 1 are effective in improving metabolic and vascular health.
- Conditions
- Glucose Intolerance, Aortic Stiffness, Vasodilation
- Trial name
- HATFF (NCT02095873)
- Testing
- Glyoxalase 1 (Glo1) inducer
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Warwick
Infections, Rotavirus
To Evaluate Immunogenicity, Reactogenicity & Safety of 2 Doses of GSK Bio HRV Liquid Vaccine Given to Infants (Vietnam)
To provide specific data on immunogenicity of GSK Biologicals' HRV liquid vaccine, when co-administered with the routine Expanded Program of Immunization (EPI) in Vietnam.
- Trial name
- NCT00345956
- Testing
- Human rotavirus liquid vaccine
- Where
- 2 sites in Vietnam
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Aging
Health in Motion Pragmatic Clinical Trial - WRAPAROUND
Falls among older adults are a serious public health concern, and injuries resulting from falls can cause significant loss of independence, premature death, and higher caregiver burden.
- Trial name
- NCT06619496
- Testing
- Human-led fall prevention program, Avatar-led fall prevention program
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Blue Marble Rehab Inc
Monkeypox
A Clinical Study Investigating the Safety and Immune Responses After Immunization With Investigational Monkeypox Vaccines
This was a dose-escalation, Phase I/II study evaluating the safety, tolerability, reactogenicity and immunogenicity of the investigational RNA-based multivalent vaccine candidate BNT166a for active immunization against monkeypox…
- Trial name
- NCT05988203
- Testing
- BNT166a
- Where
- 9 sites in United States, United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- BioNTech SE
Bites and Stings
Prevention of Jellyfish Stings
Jellyfish stings are a common occurrence among ocean-goers worldwide with an estimated 150 million envenomations annually. Fatalities and hospitalizations occur annually, particularly in the Indo-Pacific regions.
- Trial name
- NCT00114894
- Testing
- Safe Sea ™
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Diabetes, Cardiovascular Diseases
Community-Based Lifestyle Intervention for Primary and Secondary Prevention of Diabetes in Arab Women in East-Jerusalem
Given the extremely high incidence of diabetes in Arab women and the current lack of interventions, all non-diabetic women can be considered "at risk" and warrant secondary prevention.
- Conditions
- Diabetes, Cardiovascular Diseases, Health Behavior
- Trial name
- NCT04143737
- Testing
- Healthy lifestyle intervention
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Postpartum Hemorrhage
Efficacy of Four Different Treatment Regimes on Postpartum Hemorrhage
Postpartum hemorrhage is the most important cause of maternal morbidity and mortality worldwide and accounts for approximately 25% of deaths worldwide.
- Trial name
- NCT05467462
- Testing
- I.V carbetocin administration, I.V Oxytocin administration, I.V carbetocin and tranexamic acid administration
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Sexual Violence
Evaluating the Efficacy of a New Sexual Violence Prevention Program With College Students
This research project will develop, deliver, and assess the efficacy of a new sexual violence (SV) prevention program for college students.
- Trial name
- MOON Program (NCT06887361)
- Testing
- MOON Program
- Where
- Portugal
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
HIV Infections
The Implementation of Pre-exposure Prophylaxis of Injectable Cabotegravir
Although CAB LA PrEP has been proven efficacious in blinded randomized controlled clinical trials, additional research is needed to evaluate effectiveness in real world settings as well as to identify effective implementation…
- Trial name
- ImPrepCab (NCT05515770)
- Testing
- Cabotegravir Injection
- Where
- Brazil
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Evandro Chagas National Institute of Infectious Disease
Delirium
Nursing Intervention to Reduce Incidence and Duration of Delirium in Patients in Intensive Care
Introduction: Delirium is a cognitive alteration of acute onset and fluctuating course, characterized by the reduced capacity to pay attention to the environment, memory impairment, disorientation, language, and perception…
- Trial name
- NCT05172583
- Testing
- Control, Interventions to reduce delirium based on DSM and scientific evidence
- Where
- Colombia
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Universidad Surcolombiana
Maltreatment by Parent
Connected Through Coaching for Flourishing Families
Despite the known association between the quality of participant relational engagement with service providers and clinical outcomes, limited studies have examined caregiver Relational Responsiveness (RR) as a mechanism to achieve…
- Trial name
- CCFF (NCT06145451)
- Testing
- Family Success Network
- Where
- 3 sites in United States
- Volunteers
- 612 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Obesity Prevention
Activity at Ventilation Threshold on Appetite and Food Intake in Boys
The investigators hypothesize exercise increases short term appetite and food intake, and interferes with satiety and satiations to a preload in normal weight, overweight and obese boys.
- Trial name
- VeT (NCT01196351)
- Testing
- Dietary Supplement: water with noncalorie sweetener, Activity: With noncalorie sweetener or glucose
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Toronto
HIV/AIDS
A Mobile Phone Game to Prevent HIV Among Young Africans
This project will test the feasibility of an electronic game to prevent HIV among African preadolescents, delivered via inexpensive Android smart phones.
- Trial name
- NCT03054051
- Testing
- Tumaini Mobile Phone Game
- Where
- Kenya
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Emory University
Body Image, Eating Disorder Symptom
Online Expert Peer Facilitation of the EVERYbody Project
This randomized-controlled trial examines an online dissonance-based body image program for college students called the EVERYbody Project-Connect.
- Conditions
- Body Image, Eating Disorder Symptom, Weight Bias
- Trial name
- NCT05336253
- Testing
- EVERYbody Project-Connect, Self-Help Workbook
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Western Washington University
Hepatitis B
Hepatitis B Vaccination Through Syringe Exchange Programs: A Randomized, Controlled Trial of Vaccination Schedules
The investigators seek to provide immunization for individuals who are at high risk of contracting hepatitis B virus (HBV) infection because of their illicit drug use.
- Trial name
- HVS (NCT01259453)
- Testing
- Vaccination to prevent hepatitis B virus infection
- Where
- 3 sites in United States
- Volunteers
- 595 people, healthy volunteers welcome
- Sponsor
- Yale University
Aging, Physical Activity
Effects of Regular Exercise on Cerebrovascular Reserve in Older Adults
While it is well established that physical inactivity is a modifiable risk factor for vascular disease and cognitive decline, the mechanism by which exercise exerts its protective effect on the cerebral circulation and cognition…
- Conditions
- Aging, Physical Activity, Cognitive Function
- Trial name
- BIM (NCT03158337)
- Testing
- Aerobic exercise
- Where
- Canada
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- University of Calgary
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