Clinical trials: Preventive Intervention
Unspecified Adult Solid Tumor, Protocol Specific
Internet-Based Nutrition Education Program in Preventing Cancer in Participants of Health Maintenance Organizations
RATIONALE: Websites for nutrition education may be an effective method to help people eat more fruits and vegetables which may lower their risk of cancer.
- Trial name
- NCT00169312
- Testing
- behavioral dietary intervention, dietary intervention, educational intervention
- Where
- 4 sites in United States
- Volunteers
- 2,619 people, healthy volunteers welcome
- Sponsor
- Josephine Ford Cancer Center
HIV/AIDS
PrEP My Way: A Hybrid Type 1 Clinical Effectiveness-implementation Trial to Promote PrEP Persistence Among Young Kenyan Women
PrEP My Way is a novel PrEP delivery system consisting of clinic-based PrEP initiation, followed by peer-delivered kits for HIV self-testing, PrEP refills, vaginal swabs for gonorrhea and chlamydia self-sampling, pregnancy tests…
- Trial name
- NCT06566430
- Testing
- PrEP My Way intervention, PrEP My Way intervention without STI testing, Enhanced standard of care
- Where
- Kenya
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cancer
CCHW-delivered CFH-based Cancer Prevention Program Among Chinese Americans
This study evaluated a culturally and linguistically tailored cancer prevention program delivered by trained Chinese American community health workers to Chinese American adults in Texas.
- Trial name
- NCT07766252
- Testing
- Family Health History-Based Cancer Prevention and Navigation Program
- Where
- United States
- Volunteers
- 1,129 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Human Papilloma Virus
Marketability of a Technology-based Intervention to Increase HPV Vaccination
The overall goal of this SBIR Phase II project is to reduce cancer rates by marketing a brief, easily implemented technology-based intervention that increases human papillomavirus (HPV) vaccination among Planned Parenthood and…
- Trial name
- NCT03497936
- Testing
- Women's Stories
- Where
- 7 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Real Prevention, LLC
Primary Prevention of HIV Acquisition
Primary HIV Prevention in Pregnant and Lactating Ugandan Women
This study aims to test the effectiveness of a behavioral intervention aimed at preventing the primary acquisition of HIV by uninfected pregnant and lactating women in Uganda, East Africa where HIV transmission is high.
- Trial name
- PRIMAL (NCT01882998)
- Testing
- Extended repeat HIV testing and enhanced counseling
- Where
- Uganda
- Volunteers
- 1,230 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Prophylaxis Invasive Pneumococcal Diseases and Pneumonia
Safety and Efficacy Study of Investigational Pneumococcal Vaccine in Elderly Population
As the licensed Pneumovax 23™ vaccine is not always satisfactory in elderly subjects, the safety and the immune response of the new investigational pneumococcal protein vaccine is evaluated in healthy elderly population.
- Trial name
- NCT00307528
- Testing
- Pneumococcal vaccine GSK513026, Pneumovax 23™
- Where
- Belgium
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cataract Senile, Endophthalmitis
Postoperative Safety Outcomes of Intraoperative Intracameral Preservative-Free Moxifloxacin Versus Levofloxacin
Comparative safety study of intracameral levofloxacin versus moxifloxacin for postoperative infection prophylaxis
- Conditions
- Cataract Senile, Endophthalmitis, Antibiotic Side Effect, Safety Issues
- Trial name
- NCT04403334
- Testing
- Levofloxacin Ophthalmic, Moxifloxacin Ophthalmic
- Where
- Philippines
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Peregrine Eye and Laser Institute
Noncommunicable Diseases, Health Knowledge, Attitudes, Practice
School-based e-Health Non-Communicable Disease (NCD) Prevention Program
The goal of this sequential mixed method study is to assess the feasibility and effectiveness of a school-based eHealth-NCD prevention program intervention to improve adolescents' knowledge, attitude, and practices regarding NCDs…
- Conditions
- Noncommunicable Diseases, Health Knowledge, Attitudes, Practice, Non-communicable Disease Risk Factors
- Trial name
- NCT06674798
- Testing
- School-based eHealth NCD Prevention Program
- Where
- 7 sites in Pakistan
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Hemorrhage
Uterotonic Prophylaxis Trial
Excessive bleeding after dilation and evacuation (D\&E) requiring interventions is common, occurring in approximately 30% of cases at one large abortion-providing clinic.
- Trial name
- UPT (NCT02408965)
- Testing
- Methergine
- Where
- United States
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Gum Injury
Assessing Effects of a Denture Gel on Gum Abrasions
This is a parallel design study. Up to 40 subjects with a full mandibular and full maxillary dentures will be enrolled into the study. Subjects will use their current denture care +/- a treatment gel for 4 weeks.
- Trial name
- NCT04913636
- Testing
- Treatment Gel
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
HIV
PrEP With TDF/FTC to Prevent HIV-1 Acquisition in Young MSM and Transgender Women of Color
This is a 48-week prospective observational study that will allow testing of the hypothesis that a program in which pre-exposure prophylaxis (PrEP) is administered to young men of color who have sex with men (yMSMc) in a…
- Trial name
- NCT02367807
- Testing
- Emtricitabine and tenofovir disoproxil fumarate
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Philadelphia Fight
Obesity Prevention
Effect of Three Weeks Consumption of Rye Porridge Breakfast
Acute hunger-reducing effects (8h) has been documented for rye porridge breakfast compared with iso-caloric referenced refined wheat reference breakfast.
- Trial name
- NCT01117363
- Testing
- dietary intervention (rye porridge or wheat bread)
- Where
- Sweden
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Swedish University of Agricultural Sciences
Older Adults (65 Years and Older), Cognition
Effects of Breathing Exercises on Cognition in Older Adults
The goal of this interventional clinical trial is to investigate the effects of breathing exercises added to balance training on cognitive function in individuals aged 65 years and older.
- Conditions
- Older Adults (65 Years and Older), Cognition, Balance Control in Elderly, Fall Prevention in Healthy Aging
- Trial name
- NCT07505914
- Testing
- Balance Training Program, Inspiratory Muscle Training, Breathing Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Sexually Transmitted Diseases, HIV Infections
UTECH: Machine Learning for HIV Prevention Among Substance Using GBMSM
This project seeks to develop and test the acceptability, appropriateness and feasibility of uTECH, a novel social media "big data" machine learning intervention for HIV-negative substance-using sexual and gender minority people…
- Conditions
- Sexually Transmitted Diseases, HIV Infections, Implementation Science, Substance Use
- Trial name
- uTECH (NCT04710901)
- Testing
- uTECH + YMHP, YMHP, uTECH
- Where
- United States
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
HIV, HIV Pre-exposure Prophylaxis
Safety and Pharmacokinetic Study of Oral MK-8527 QM in Participants at Low-Risk for HIV-1 Infection (MK-8527-007)
This double-blind, placebo-controlled study was designed to assess the safety, tolerability, and pharmacokinetics of oral MK-8527 taken once monthly (QM) in participants at low risk for human immunodeficiency virus Type 1 (HIV-1)…
- Trial name
- NCT06045507
- Testing
- MK-8527
- Where
- 18 sites in United States, Israel and 1 more
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
HIV Prevention, STD Prevention
Adopting and Demonstrating the Adaptation of Prevention Techniques: Community PROMISE PLUS
This project will pilot test a step-by-step guide developed by CDC for organizations to engage in evidence-based adaptation of interventions previously shown to be effective in research settings for use in real world…
- Trial name
- NCT00267436
- Testing
- Community PROMISE
- Where
- 2 sites in United States
- Volunteers
- 574 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Post Partum Hemorrhage, Fibrinolysis; Hemorrhage
Tranexamic Acid for Prevention of Hemorrhage in Cesarean Delivery
The investigators prepared a novel study of tranexamic acid (TXA) designed to estimate the quantity of blood loss in women undergoing elective repeat cesarean deliveries.
- Conditions
- Post Partum Hemorrhage, Fibrinolysis; Hemorrhage, Blood Loss
- Trial name
- TXA (NCT03856164)
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Second Hand Tobacco Smoke, Tobacco Smoking
Air Quality Feedback to Reduce Second-hand Smoke (SHS) Exposure in the Home
This is a European study which is part of a larger research project (The TackSHS project) funded by the European Union's Horizon 2020 Research and Innovation Programme (Grant Agreement No 681040) and led by the Catalan Institute…
- Conditions
- Second Hand Tobacco Smoke, Tobacco Smoking, Tobacco Use
- Trial name
- TackSHSWP4 (NCT03151421)
- Testing
- Home air quality monitoring and feedback
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Institut Català d'Oncologia
HIV Infections
A School-Based HIV/STD Prevention Program to Reduce Risky Sexual Behaviors Among Adolescents in Liberia
This study will evaluate the effectiveness of a school-based HIV/sexually transmitted disease prevention program in reducing sexual risk behaviors of youth attending school in Liberia.
- Trial name
- NCT00698321
- Testing
- HIV/STD prevention curriculum, General health promotion curriculum
- Where
- Liberia
- Volunteers
- 866 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Colorectal Cancer
Preliminary Investigation of β-hydroxybutyrate Supplementation in Colorectal Cancer Prevention
The aim of this study is to assess the feasibility of beta-hydroxybutyrate (BHB) supplementation in individuals who are undergoing a standard-of-care colonoscopy or flexible sigmoidoscopy.
- Trial name
- BHB-CRC (NCT05338307)
- Testing
- R-1,3-Butanediol
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
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