Clinical trials: Preventive Intervention
Prevention
Glucose Observation and Wearable Use for Prevention
The GLOW UP study is a single-center, prospective, observational case-control study conducted in St. Gallen, Switzerland. The primary aim of the study is to examine to what degree lifestyle data collected from wearable devices…
- Trial name
- GlowUp (NCT07373418)
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of St.Gallen
Obsessive Compulsive Disorder
Application of Vagal Stimulation in Exposure and Response Prevention for Obsessive Compulsive Disorder
Obsessive Compulsive Disorder (OCD) is a condition associated with recurrent intrusive distressing thoughts, images and urges compelling the person to perform neutralizing acts or thoughts to the extent of significantly…
- Trial name
- NCT02196090
- Testing
- Exposure and Response Prevention, Cold face gel mask
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- King's College London
Cervical Cancer Screening
Improving Cervical Cancer Screening in Women Living With HIV Attending Chronic Disease Clinics in Semi-rural Tanzania
This study is to analyse the effect of a bundle of measures on the proportion of females being screened for cervical cancer in the Kilombero and Ulanga Antiretroviral Cohort (KIULARCO), comparing the time period before…
- Trial name
- NCT05256862
- Testing
- Data collection
- Where
- Tanzania
- Volunteers
- 2,974 people
- Sponsor
- University Hospital, Basel, Switzerland
Radical Cystectomy, Surgical Site Infection
Optimized Perioperative Antibiotic Prophylaxis in Radical Cystectomy
Cystectomy with urinary diversion (ileal conduit, orthotopic ileal bladder substitute, continent catheterizable pouch) is the best treatment option for patients with muscle-invasive bladder cancer.
- Conditions
- Radical Cystectomy, Surgical Site Infection, Urologic Cancer, Perioperative/Postoperative Complications
- Trial name
- PAPRAC (NCT03305627)
- Testing
- Short PAP, Extended PAP
- Where
- 2 sites in Switzerland
- Volunteers
- 196 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Gastric Cancer
Gastric Cancer Prevention for Indigenous Peoples
The incidence of gastric cancer in local indigenous peoples is higher than the non-Indigenous counterpart in Taiwan. How to design an effective prevention strategy for gastric cancer is of importance.
- Trial name
- NCT03900910
- Testing
- Gastric cancer prevention, Execution of the program
- Where
- Taiwan
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Type 2 Diabetes, Obesity
Diabetes Virtual Trek: Obesity and Diabetes Prevention Through Science Enrichment
The purpose of this study was to evaluate the effectiveness of a school-to-home education program for it's ability to increase knowledge about, and ability to prevent type two diabetes in children and parents.
- Trial name
- DvtENERGY (NCT00542113)
- Testing
- DvtProgram ENERGY, DvtProgramENERGY
- Where
- 2 sites in United States
- Volunteers
- 1,703 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Migraine Without Aura, Migraine With Aura
Dose Ranging Study of the Efficacy and Tolerability of Tonabersat in the Prophylaxis of Migraine Headache
Primary objective: To investigate the efficacy and tolerability of two doses of tonabersat compared to placebo in the prophylaxis of migraine headache and to evaluate the longer term tolerability of tonabersat in an open label…
- Trial name
- TEMPUS (NCT00534560)
- Testing
- Tonabersat
- Volunteers
- 542 people
- Sponsor
- Minster Research Ltd
Death, Sudden, Cardiac, Ventricular Fibrillation
PREVENTION-ACHD Risk Score
Sudden cardiac death (SCD) is one of the major causes of mortality in adults with congenital heart disease (ACHD). Risk stratification for sudden cardiac death in this patient group is challenging and at the current moment there…
- Conditions
- Death, Sudden, Cardiac, Ventricular Fibrillation, Ventricular Tachycardia, Congenital Heart Disease
- Trial name
- PREVENTIONACHD (NCT03957824)
- Testing
- PREVENTION-ACHD risk score
- Volunteers
- 783 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
HIV Infections, Risk Reduction
Seroincidence Study Among Men Who Have Sex With Men and Transgender Women - The ImPrEP Seroincidence Study
PrEP (pre-exposure prophylaxis) is an effective prevention strategy in which HIV-negative individuals take antiretroviral drugs (tenofovir disoproxil fumarate and emtricitabine - TDF/FTC) to reduce HIV acquisition.
- Conditions
- HIV Infections, Risk Reduction, Risk Behavior, Risky Health Behavior
- Trial name
- Seroincidence (NCT05674682)
- Testing
- HIV testing
- Where
- 2 sites in Brazil
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Evandro Chagas National Institute of Infectious Disease
Hemophilia A
Outcomes of Prophylaxis With Emicizumab in Children With Severe Hemophilia A in Ivory Coast
Assessment of the outcomes of prophylaxis with Emicizumab in children with severe hemophilia A in Ivory Coast
- Trial name
- NCT05279924
- Testing
- Prophylaxis with Emicizumab
- Where
- Côte d’Ivoire
- Volunteers
- 33 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Anxiety
FRIENDS as an Indicative Prevention Program in Norway
The purpose of this pilot-study is to evaluate a cognitive behavioral program, the Friends-program, as indicated prevention for anxious youth.
- Trial name
- NCT01802424
- Testing
- The Friends program
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- NORCE Norwegian Research Centre AS
Post-traumatic Stress Disorder
Interest of Cardiac Coherence in the Prevention of Chronic Post-traumatic Stress Disorder: Pilot Study
ThThe aim of this study is to determinate the potential benefits of a respiratory training program (cardiac coherence, CC) in patients suffering from acute stress disorder, after a potentially traumatic event.
- Trial name
- COHEPS-P (NCT04701723)
- Testing
- cardiac coherence
- Where
- Reunion
- Volunteers
- 44 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Seasonal Influenza
Immunogenicity of Seasonal Influenza by Delivery Directly to Ileum
the purpose of the study is to determine the safety and tolerability of VXA-A1.1, an adjuvanted adenoviral based influenza vaccine, when delivery is targeted to the ileum, using a radio controlled capsule.
- Trial name
- ICC H1 (NCT01761123)
- Testing
- VXA-A1.1
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Vaxart
CIN3, CIN2
Cervical Cancer Screening With Human Papillomavirus Testing
HPV testing for primary cervical cancer screening of women over 30 years of age is likely to become the standard of care in the near future in many areas of the world.
- Conditions
- CIN3, CIN2, Cervical Cancer
- Trial name
- ESTAMPA (NCT01881659)
- Testing
- HPV screening
- Where
- 12 sites in Argentina, Bolivia and 7 more
- Volunteers
- 50,000 people
- Sponsor
- International Agency for Research on Cancer
Post-operative Nausea and Vomiting, Laparoscopic Sleeve Gastrectomy
Designing Optimal Prevention and Management of Postoperative Nausea and Emesis for Patients Undergoing Laparoscopic Sleeve Gastrectomy
Bariatric surgery remains the most effective therapy for obesity. Postoperative nausea and vomiting (PONV) are commonly reported following bariatric surgery.
- Trial name
- NCT03435003
- Testing
- Aprepitant 80 mg Oral Capsule, scopolamine transdermal, Total intravenous anesthesia
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Hematologic Malignancies, Relapse
Phase 1/2 Study of Carfilzomib for the Prevention of Relapse and GVHD in Allo-HCT for Hematologic Malignancies
The investigators hypothesize that adding carfilzomib to standard conditioning regimen for allo-HCT for advanced or high-risk hematologic malignancies will decrease post-transplant relapse and treatment-related mortality by…
- Conditions
- Hematologic Malignancies, Relapse, Graft-Versus-Host Disease
- Trial name
- NCT02145403
- Testing
- Carfilzomib, Tacrolimus
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Michigan Rogel Cancer Center
Influenza
Study to Evaluate the Immunogenicity and Safety of 2 Formulations of GlaxoSmithKline (GSK) Biologicals' GSK1247446A Low Dose Influenza Vaccine Candidate
The purpose of this study is to evaluate the immunogenicity and the safety of candidate vaccines compared to Fluarix™ administered intramuscularly in subjects aged 18-59 years
- Trial name
- NCT00374842
- Testing
- Fluarix™, GSK1247446A
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Childhood Influenza Vaccination, School-located Influenza Vaccination
Evaluation of the School Kids Influenza Prevention Project
Children whose parents receive text reminders are more likely to be consented to participate in the school located influenza vaccination clinic than children whose parents do not receive text reminders.
- Trial name
- SKIPP (NCT03307642)
- Testing
- Text message notification
- Where
- United States
- Volunteers
- 18,540 people
- Sponsor
- University of Rochester
Heart Surgery
Association Between S-LAAO and Adverse Cardiovascular Events Among Patients Undergoing Coronary Artery Bypass Grafting.
This is a prospective, single-center, randomized, active controlled, clinical trail to assess the efficacy and safety of surgical closure of left atrial appendage (LAA) in patients undergoing coronary artery bypass graft.
- Trial name
- NCT04108169
- Testing
- Left atrial appendage occlusion surgery
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Beijing Institute of Heart, Lung and Blood Vessel Diseases
Acute Lymphoblastic Leukaemia - Category
CiproPAL (Ciprofloxacin Prophylaxis in Acute Leukaemia)
CiproPAL is a randomised trial comparing daily ciprofloxacin with local standard care during the induction phase of paediatric ALL treatment, and aims: 1.
- Trial name
- CiproPAL (NCT04678869)
- Testing
- Ciprofloxacin, Antibiotic
- Where
- 14 sites in United Kingdom
- Volunteers
- 313 people
- Sponsor
- University College, London
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.