Clinical trials: Preventive Intervention
Obesity (Disorder)
AI-INFORMED PEER-MENTORING BEHAVIORAL INTERVENTION FOR OBESITY AND CARDIOVASCULAR DISEASE PRIMARY PREVENTION IN YOUTH
The goal of this clinical trial is to learn if an AI-based peer-mentoring works to prevent obesity in adolescents and young adults.
- Trial name
- PeerMentorOBCV (NCT07505459)
- Testing
- AI-informed behavioral intervention, Standard behavioral intervention, Health Education
- Where
- 3 sites in Greece, Italy and 1 more
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Aikaterini Karaivazoglou
Obesity
Prevention of Abdominal Incisional Hernia After Laparoscopic Digestive Surgery in Obese Patients (BMI>30kg/m2)
The hypothesis of this study is to show that after laparoscopic digestive surgery in obese patients (BMI>30kg/m2), the wearing of an abdominal support belt is an effective treatment for the Incisional Hernia and feasible in terms…
- Trial name
- EVINOV (NCT04537546)
- Testing
- OBESINOV elasto-compressive belt
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Institut Mutualiste Montsouris
Atrial Fibrillation
Secondary Prevention of Atrial Fibrillation (Impact of Renin-Angiotensin-Aldosterone System Inhibition)
In the present application, we propose to refine and extend current insight into AAF mechanism and therapy by examining the importance of pharmacologic RAAS inhibition, ACE genotype, and their interaction in secondary AF…
- Trial name
- NCT01233635
- Testing
- no drug, start cozaar, continue cozaar
- Where
- United States
- Volunteers
- 228 people
- Sponsor
- University of Pittsburgh
Obesity, PreDiabetes
Reducing Cardiometabolic Risk and Promoting Functional Health in Older Adults With Obesity and Prediabetes
Obesity and pre-diabetes threatens the overall health and functional independence of older adults but lifestyle weight management for diabetes prevention, soon to be reimbursed by Medicare, can reduce this burden.
- Conditions
- Obesity, PreDiabetes, Aging
- Trial name
- Sustain-DPP (NCT03500640)
- Testing
- DPP Intensive: 30-minute calls, DPP Support: 15-minute calls
- Where
- United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Human Papillomavirus-Related Cervical Carcinoma
Self-Collection for Cervical Cancer Screening and HPV Vaccination for Cancer Prevention Among Women in Emergency Care in Northeast Florida
Human Papilloma Virus (HPV) is a cause of cervical cancer in women. This study is being done to identify sites for cervical cancer screening and education regarding HPV vaccination outside of the traditional settings of primary…
- Trial name
- NCT06607874
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Transient Ischemic Attack
Telestroke for Comprehensive Transient Ischemic Attack Care in Acute Stroke Ready Hospitals
TELECAST-TIA is a prospective single-center study evaluating guideline-based transient ischemic attack (TIA) treatment at an Acute Stroke Ready Hospital (ASRH) pre- and post-initiation of a specialist telestroke inpatient…
- Trial name
- TELECAST-TIA (NCT03724110)
- Testing
- Telestroke
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Minnesota
Sports Injury
Prevention of Injuries in Young Athletics (Track and Field) Athletes
The long-term purpose of an on-going participatory action research program "The KLUB-study" in Sweden, that involves scientists and representatives from all levels of athletics, is to develop a sustainable framework for safe…
- Trial name
- NCT03459313
- Testing
- Active group
- Where
- Sweden
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Bacteremia, Neoplasms
Taurolidine Lock Solution in the Prevention of Catheter Related Bacteremia
Children with cancer need a long term tunnelled central venous catheter (TCVC) for the entire duration of their treatment. TCVCs are locked with heparin when not in use.
- Trial name
- NCT00735813
- Testing
- Taurolock, Heparin
- Where
- Denmark
- Volunteers
- 129 people
- Sponsor
- Aarhus University Hospital
COVID-19
A Study to Evaluate the Efficacy and Safety of Ivermectin in COVID-19 Prevention
A multicenter, randomized, double-blind, placebo-controlled, study to evaluate the efficacy and safety of oral ivermectin tablets versus placebo for COVID-19 prophylaxis
- Trial name
- SAIVE (NCT05305560)
- Testing
- Ivermectin Tablets
- Where
- Bulgaria
- Volunteers
- 400 people
- Sponsor
- MedinCell S.A
Coronary Artery Disease
Aspirin Effectiveness Study
Aspirin is an effective medicine for prevention of heart attacks in patients with coronary artery disease and works by preventing clots from forming.
- Trial name
- NCT01113060
- Where
- Ireland
- Volunteers
- 500 people
- Sponsor
- Royal College of Surgeons, Ireland
Non-Valvular Atrial Fibrillation
A Study to Collect Information on the Characteristics of Elderly Belgian Patients With NVAF That Are Treated With a NOAC for This Indication With a Special Focus on Their Fear of Bleeding While Using a NOAC vs the Clinical Benefit of a NOAC of Thrombosis/Stroke Prevention.
Atrial fibrillation is a heart condition that causes an abnormal and fast heart rate. For people with non-valvular atrial fibrillation (NVAF), this is caused by problems such as high blood pressure and diabetes.
- Trial name
- BELANCE (NCT04722679)
- Testing
- Non-VKA Oral Anticoagulants (NOAC)
- Where
- Belgium
- Volunteers
- 103 people
- Sponsor
- Bayer
Chemotherapy-induced Neutropenia, Lymphoma
Mecapegfilgrastim(PEG-G-CSF) for Prophylaxis of Chemotherapy-induced Neutropenia in Patients With Lymphoma
Neutropenia is one of the most frequent adverse effects of chemotherapy, and the main factor to limit the dosage and the continuation of chemotherapy.A newly pegylated rhG-CSF was independently developed by JIANGSU HENGRUI…
- Trial name
- NCT04460508
- Testing
- Pegylated rhG-CSF, rhG-CSF
- Where
- China
- Volunteers
- 170 people
- Sponsor
- The First Hospital of Jilin University
HIV Pre-exposure Prophylaxis Use
PrEP4U: Assessing the Effectiveness of Integrated Same-Day Lenacapavir Initiation and Follow-up Choice on PrEP Persistence
PrEP4U is designed as a pragmatic, randomized implementation trial to test strategies that could directly inform real-world roll-out of lenacapavir.
- Trial name
- NCT07335289
- Testing
- Choice of follow up, Follow up via standard clinic
- Where
- 2 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Weight Gain Trajectory, BMI
Evaluating Care Integration Between Pediatric Primary Care Providers and WIC Nutritionists
This study looks at whether using secure digital systems to share information between pediatric health care providers (during regular well-child visits) and social care providers (during regular visits with WIC nutritionists) can…
- Conditions
- Weight Gain Trajectory, BMI, Responsive Parenting, Diet Quality
- Trial name
- WEE Baby (NCT07494097)
- Testing
- Data integration around responsive parenting, Standard Care (in control arm)
- Where
- United States
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Penn State University
Fall, Fall Injury
Geriatric Emergency Department Fall Injury Prevention Project
This prospective randomized study will assess an emergency department (ED) based prevention strategy in geriatric patients at high risk for recurrent falls and injury.
- Conditions
- Fall, Fall Injury, Emergencies
- Trial name
- GREAT-FALL (NCT05807724)
- Testing
- Phone-based fall-prevention strategy, Home-visit fall prevention strategy
- Where
- United States
- Volunteers
- 644 people
- Sponsor
- Florida Atlantic University
Transplantation Infection, Epstein-Barr Virus Infections
ValGanciclovir Versus ValAcyclovir for Viral Prophylaxis in Kidney Transplantation
Our study will compare all kidney transplant recipients receiving valganciclovir vs. valacyclovir for one year following kidney transplant and compare: 1.
- Conditions
- Transplantation Infection, Epstein-Barr Virus Infections, Cytomegalovirus Infections
- Trial name
- NCT01972035
- Testing
- Valacyclovir, Valganciclovir
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- University of Minnesota
Hiv, Contraception Behavior
TwySHE - An Mhealth Peer-navigator Intervention to Increase PrEP and Contraceptive Use
The goal of this clinical trial is to learn if the TwySHE intervention can increase the use of HIV prevention in at-risk female university students aged 18-24 in Zambia.
- Trial name
- NCT06852508
- Testing
- TwySHE
- Where
- Zambia
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Prevention
Study on the Effectiveness of a School-Based Fat Loss Program for Adolescents
The students were divided into an intervention group and a control group. The intervention group attended fat loss exercise classes three times a week and the parents cooperated with us in dietary monitoring and control.
- Trial name
- NCT06524908
- Testing
- Exercise and dietary calorie restriction
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aiyoudong Children and Youth Sports Health Research Institute
Fuchs' Endothelial Dystrophy
Evaluation of Amphotericin B in Optisol-GS for Prevention of Post-Keratoplasty Fungal Infections.
With the increasing popularity of endothelial keratoplasty, a coincident increase in the rate of fungal infections post-keratoplasty has been seen in the United States.
- Trial name
- NCT04018417
- Testing
- Amphotericin B
- Where
- United States
- Sponsor
- Cornea Research Foundation of America
Bronchiectasis, Inflammation
Bronchiectasis and Long Term Azithromycin Treatment
1. SUMMARY Rationale: Patients with bronchiectasis often experience lower respiratory tract infections with progression of symptoms and decline in quality of life.
- Trial name
- BAT (NCT00415350)
- Testing
- Azithromycin
- Where
- 16 sites in Netherlands
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- W.G.Boersma
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