Clinical trials: Preventive Intervention
Lupus Erythematosus, Systemic
Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE)
The purpose of this study is: 1. To assess the efficacy of a lipid-lowering agent (atorvastatin) on the development of atherosclerosis that predisposes children with SLE to cardiovascular events in adulthood. 2.
- Trial name
- NCT00065806
- Testing
- Atorvastatin
- Where
- United States
- Volunteers
- 221 people
- Sponsor
- Laura Schanberg
Emotional Problem
Emotional Problems in Preschool Children: Evaluation of the SuperKids Program (PRE-KIDS)
Emotional problems are among the most frequent psychological problems in the school stage, having an early onset. When they are not detected and they do not receive adequate intervention, they persist and become chronic, being…
- Trial name
- NCT06419933
- Testing
- The SuperKids Program
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Colorectal Neoplasm, Colonic Polyps
Clinical Study of Real Time Colorectal Polyp Diagnosis During Colonoscopy - the VALID Colonoscopy Study
The investigators hypothesize that high definition colonoscopy with close focus narrow band imaging features has a high diagnostic accuracy for colorectal polyp histology, and can replace formal pathologic assessment in cases of…
- Trial name
- VALID (NCT01288833)
- Testing
- Close focus HD NBI Colonoscopy System
- Where
- 2 sites in United States
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Chronic Kidney Diseases
Role of AST120 for Sarcopenia Prevention in Pre-dialysis Chronic Kidney Disease
This study is to assess the effect of 48 weeks administration of Renamezin capsule on prevention of sarcopenia in pre-dialysis patients with chronic kidney disease.
- Trial name
- RECOVERY (NCT03788252)
- Testing
- Renamezin
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Gumi Cha Medical Center
Adolescent Behavior, Group, Peer
Creating Peace: Community-based Youth Violence Prevention to Address Racism and Discrimination
This cluster-randomized community-partnered study will examine the effectiveness of a trauma-sensitive, gender transformative youth violence prevention program called Creating Peace that integrates racism and discrimination…
- Conditions
- Adolescent Behavior, Group, Peer, Violence, Non-accidental, Violence, Sexual
- Trial name
- NCT04474158
- Testing
- Creating Peace, Job Readiness
- Where
- United States
- Volunteers
- 581 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Acute Respiratory Failure
Prevention of Damage Induced by Facial Mask Ventilation
In patients with acute respiratory failure (ARF) undergoing noninvasive ventilation (NIV), the main complication of the use of the mask is the development of decubitus, sometimes so severe and painful as to force a suspension of…
- Trial name
- 3PROSNIV (NCT01351155)
- Testing
- Skin protective dressing device
- Where
- Italy
- Volunteers
- 252 people
- Sponsor
- Ospedale San Donato
Stroke
Stroke Prevention and Treatment System in Shanghai: a Network of Public Healthcare of Stroke
The Shanghai Stroke Service System（4S） has been established as the network of stroke care in greater Shanghai metropolitan area.
- Trial name
- SSSS (NCT02735226)
- Testing
- stroke network and policy intervention
- Where
- 11 sites in China
- Volunteers
- 100,000 people
- Sponsor
- Shanghai Stroke Service System
Prevention of Meningococcal Infection
Kinetics of B Cell Response in Infants Menjugate Vaccination
Kinetics of B cell response in infants Menjugate vaccination
- Trial name
- NCT00310700
- Testing
- Meningococcal C conjugate vaccine
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Novartis
Rabies Prevention
A Phase III Clinical Trial on Immunogenicity and Safety of Lyophilized Rabies Vaccine for Human Use (Human Diploid Cell)
Neutralizing antibody seroconversion rate and geometric mean concentration in seronegative participants of each group at 14 days after the first dose of immunization.
- Trial name
- NCT07500207
- Testing
- Experimental Lyophilized Human Rabies Vaccine (Human Diploid Cell), approved Rabies vaccine
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Changchun BCHT Biotechnology Co.
Elbow Dislocation, Heterotopic Ossification
Tranexamic Acid Prophylaxis for Heterotopic Ossification in Elbow Fracture-Dislocation Surgery
Heterotopic ossification (HO) following elbow fracture-dislocation is a well-recognized condition that can lead to reduced range of motion, increased pain, and the necessity for repeat surgeries.
- Trial name
- NCT06088407
- Testing
- with Tranexamic acid
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Assaf-Harofeh Medical Center
Preventive Care
Impact of a Health Intervention on Some Indicators in the Care of Chronic Complex Patient (CCP).
The aim of this study is to assess the effectiveness of proactive and integrated healthcare program for chronic complex patients (CCP).
- Trial name
- CCP (NCT03091036)
- Testing
- Proactive healthcare intervention
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- María José del Olmo Rubio
HIV
SCOPE: Strategies to Combine PrEP With Prevention Efforts
This pilot, open-label, prospective study will determine the feasibility of integrating pre-exposure prophylaxis (PrEP) into existing HIV prevention programs for female sex workers and if women who are enrolled in those programs…
- Trial name
- SCOPE (NCT01832571)
- Testing
- Once daily Truvada®
- Where
- 2 sites in Kenya
- Volunteers
- healthy volunteers welcome
- Sponsor
- FHI 360
Disease, Chronic
Efficacy of Different Behaviour Change Techniques in MyPlan 2.0
The aim of this study is to investigate the effectiveness of intervention 'MyPlan 2.0' and the efficacy of the different behaviour change techniques that are included.
- Trial name
- NCT03274271
- Testing
- Action planning, Coping planning, Self-monitoring
- Where
- Belgium
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University Ghent
Akathisia
Prophylaxis Against Metoclopramide-Induced Akathisia
ABSTRACT Study Objective: To compare the effects of midazolam and diphenhydramine for the prevention of metoclopramide induced akathisia.
- Trial name
- NCT01051271
- Testing
- midazolam
- Volunteers
- 225 people
- Sponsor
- Pamukkale University
Obesity
A 14-Month Study On The Effects Of CP-945,598 For The Prevention Of Weight Regain In Obese Patients
The purpose of this study is to determine if CP-945,598 is effective in the prevention of weight regain in obese subjects.
- Trial name
- NCT00483171
- Testing
- CP-945,598, Non-pharmacological weight loss program (NPP), Low Calorie Diet
- Where
- 26 sites in United States, Australia and 3 more
- Volunteers
- 699 people
- Sponsor
- Pfizer
Cancer, Tumors
Ramosetron, Aprepitant, and Dexamethasone Versus Palonosetron, Aprepitant, and Dexamethasone
The purpose of this study is to compare the anti-emetic effect of ramosetron plus aprepitant and dexamethasone with palonosetron plus aprepitant and dexamethasone in patients receiving highly emetogenic chemotherapy.
- Trial name
- RAPA (NCT02532634)
- Testing
- ramosetron, aprepitant, dexamethasone, palonosetron, aprepitant, dexamethasone
- Where
- 10 sites in South Korea
- Volunteers
- 292 people
- Sponsor
- Kangdong Sacred Heart Hospital
Breast Cancer, Drug/Agent Toxicity by Tissue/Organ
Pyridoxine and Topical Urea/Lactic Acid-Based Cream in Preventing Hand-Foot Syndrome in Patients Receiving Capecitabine for Breast Cancer or Other Cancer
RATIONALE: Pyridoxine (vitamin B6) and topical urea/lactic acid-based cream may prevent or lessen hand-foot syndrome caused by chemotherapy.
- Conditions
- Breast Cancer, Drug/Agent Toxicity by Tissue/Organ, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00296036
- Testing
- pyridoxine hydrochloride, urea/lactic acid-based topical cream
- Where
- 231 sites in United States
- Volunteers
- 137 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Doxorubicin Induced Cardiomyopathy
Role of Statin Therapy in Prevention of Anthracycline-Induced Cardiotoxicity
This study aims at evaluating the role of Atorvastatin in prevention of Anthracycline induced cardiotoxicity
- Trial name
- NCT05792293
- Testing
- Atorvastatin 40 Mg Oral Tablet
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Delirium, Intensive Care Unit, Randomised Controlled Trial
The Effects of a Model-based Sensory Stimulation Intervention on Preventing Delirium Among Intensive Care Unit Patients: A Randomised Controlled Trial
Delirium is highly associated with adverse clinical outcomes of intensive care unit (ICU) patients, including increased cognitive impairment, duration of intubation, ICU length of stay, mortality, physical dependence, and health…
- Trial name
- NCT04306016
- Testing
- Sensory stimulation
- Where
- China
- Volunteers
- 152 people
- Sponsor
- Chinese University of Hong Kong
Obesity
Digital Intervention for Behaviour Change and Chronic Disease Prevention
Body weight, diet quality, physical activity, stress, sleep and alcohol use will be evaluated in a sample of 180 Albertans with excess body weight.
- Trial name
- DIRECTION (NCT05579704)
- Testing
- Web-based wellness platform, Healthcare professional-facilitated online support group
- Where
- Canada
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University of Alberta
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