Clinical trials: Preventive Intervention
Hiv, Minority Stress
Developing an Online Mindfulness-based Intervention to Reduce Minority Stress and HIV Risk Among Young Adult MSM - Aim 3
The overall aim of the research study is to develop and test a mindfulness-based program for young adult gay, bisexual, and queer men at risk for HIV (Brown University IRB approved protocol #2004002698).
- Conditions
- Hiv, Minority Stress, Mental Health Wellness 1
- Trial name
- MBQR (NCT05855655)
- Testing
- Mindfulness-Based Queer Resilience (MBQR)
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Brown University
Hepatitis C, HIV Infections
Coaching for HCV and HIV
The objective of this study is to determine the feasibility and acceptability of a peer recovery coach (PRC) intervention to improve linkage to hepatitis C (HCV) and/or human immunodeficiency virus (HIV) care, treatment…
- Conditions
- Hepatitis C, HIV Infections, Opioid-use Disorder
- Trial name
- NCT04314414
- Testing
- PRC brief motivational interview intervention, Phone contact
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Boston Medical Center
HIV Infection
Enhancement of Connect to Protect® (C2P)
The proposed study seeks to continue Connect to Protect® (C2P) community mobilization efforts that have developed coalitions that plan for and bring about structural changes for purposes of reducing HIV incidence and prevalence…
- Trial name
- NCT01492816
- Testing
- Community Mobilization
- Where
- 9 sites in United States
- Volunteers
- 927 people
- Sponsor
- University of North Carolina, Chapel Hill
HIV Infections, Sexually Transmitted Diseases
HORIZONS HIV Intervention
The Horizons Program will test the efficacy of a multi-session HIV prevention program for African American female teens attending reproductive health clinics in Atlanta, GA.
- Trial name
- HORIZONS (NCT00633906)
- Testing
- HORIZONS HIV Intervention, enhanced standard-of-care
- Where
- 3 sites in United States
- Volunteers
- 715 people, healthy volunteers welcome
- Sponsor
- Emory University
Rheumatic Heart Disease
A Non-Inferiority Trial of Stopping Penicillin in Early Rheumatic Heart Disease: GOAL-Stop
GOAL-Stop is a randomized, controlled, non-inferiority trial designed to evaluate whether discontinuing secondary antibiotic prophylaxis (SAP) is non-inferior to continuing SAP in preventing progression of rheumatic heart disease…
- Trial name
- GOAL-Stop (NCT07146048)
- Testing
- Secondary Prophylaxis
- Where
- Uganda
- Volunteers
- 922 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
COPD Exacerbation Acute
Prevalence of Humoral Dysfunction in Pts With Frequent Exacerbations of COPD, and the Effect of SCIgR for Prevention
To examine the prevalence of humoral immunodeficiency in patients with Chronic Obstructive Pulmonary disease (COPD) by evaluating both immunoglobulin levels and vaccine responses.
- Trial name
- NCT05764993
- Testing
- CUVITRU - Ig subcutaneous human 20%, Standard Medical Therapy
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Rochester General Hospital
Acute Myeloid Leukemia, Allogeneic Haematopoietic Progenitor Cell Transplant
Nebulized Liposomal Amphotericin B Ambisome for Prophylaxis of Invasive Pulmonary Aspergillosis
The trial is planned as a multicentric, national, phase II, open-label trial to evaluate safety and tolerance of nebulized Liposomal Amphotericin B (Ambisome) for LMA patients during the induction therapy ,intensification, plus…
- Trial name
- AMBINEB (NCT00391014)
- Testing
- liposomal Amphotericine B
- Where
- 4 sites in Spain
- Volunteers
- 150 people
- Sponsor
- PETHEMA Foundation
Atrial Fibrillation, Cardiac Surgery
Intravenous Metoprolol Versus Intravenous Amiodarone in the Prevention of Atrial Fibrillation After Cardiac Surgery
The aim of the study is to test the efficiency of intravenous administration of metoprolol versus intravenous administration of amiodarone in the prevention of atrial fibrillation after cardiac surgery.
- Trial name
- NCT00784316
- Testing
- metoprolol, amiodarone
- Where
- Finland
- Volunteers
- 316 people
- Sponsor
- Kuopio University Hospital
Haemophilus Influenzae Type b (Hib) Infection
Study in Infants (6-12 Months) Comparing Two Doses of a Monovalent Glycoprotein-Conjugated (Diptheria Toxin -CRM197) Vaccine Versus a Tetanus Toxoid-Conjugated Vaccine Available for the Prevention of Haemophilus Influenzae Type b Infections in China
This study will evaluate the safety and efficacy of two doses of two commercially available vaccines used to prevent Haemophilus influenzae type b infections in children 6-12 months of age.
- Trial name
- NCT01044316
- Testing
- Haemophilus influenzae type b (Hib) vaccine
- Where
- China
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Atelectasis
High Fresh Gas Flow After Intubation
Atelectasis is common during and after general anesthesia. Atelectasis develops early if preoxygenation with 100% oxygen is used and continuously used during induction until endotracheal intubation.
- Trial name
- NCT02216006
- Testing
- Control group, conventional ventilatory settings, High fresh gas flow, high minute ventilation
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Region Västmanland
Postpartum Depression
PREVENTION OF POSTPARTUM DEPRESSION DEVELOPMENT IN WOMEN WITH VERY HIGH RISK
Postpartum depression is a disease with a prevalence of 10% which has not only deleterious consequences for the mother but also for the baby and can delay the physical, social and cognitive development of the baby.
- Trial name
- PROGEA (NCT02323152)
- Testing
- psychoeducation, Standard care
- Volunteers
- 135 people
- Sponsor
- Basque Health Service
Delirium in Old Age, Delirium in the Intensive Care Unit
Multi-Component Delirium Prevention Bundle in Older Cardiac Intensive Care Unit Patients
The goal of this randomized controlled clinical trial is to learn whether a structured delirium prevention protocol can reduce the occurrence of delirium in older adults admitted to the cardiac intensive care unit (CICU).
- Conditions
- Delirium in Old Age, Delirium in the Intensive Care Unit, Delirium Confusional State, Delirium
- Trial name
- CICUDEL (NCT07776184)
- Testing
- Multicomponent Delirium Prevention Bundle, Control Group
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Tel Aviv Medical Center
Impaired Glucose Tolerance, Prediabetic State
Cardiovascular Disease (CVD) Risk and Prevention in Early Glucose Intolerance
The purpose of this study is to determine whether cardiovascular disease (CVD) risk markers, β-cell function, and insulin sensitivity can be improved by targeting mechanisms of both diabetes and CVD - using an antioxidant, an…
- Trial name
- NCT00122447
- Testing
- Aspirin, Alpha lipoic acid, Olmesartan
- Where
- 2 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Emory University
Postoperative Nausea and Vomiting
Combination Antiemetic Regimen for Prevention of PONV in Breast Surgery Patients
The purpose of this study is to compare the efficacy of the use of oral aprepitant in combination with intravenous ondansetron and dexamethasone with the efficacy provided by the use of oral aprepitant and dexamethasone for…
- Trial name
- NCT00738621
- Testing
- Aprepitant, Dexamethasone, Ondansetron
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Scott and White Hospital & Clinic
Obesity
Motivating Increases in Physical Activity for Prevention of Weight Regain After Metabolic Bariatric Surgery
The goal of this clinical trial is to learn if a psychological intervention can increase regular physical activity to help prevent weight regain after metabolic bariatric surgery in adults.
- Trial name
- NCT06484621
- Testing
- Acceptance and Commitment Therapy-Based Physical Activity Intervention, Physical Activity Education Control
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Hartford Hospital
Healthy, Healthy Adult Male
AI-Based Hamstring Injury Risk Analysis and Effects of the FUNBALL Program
This study investigates hamstring injury risk in football players using artificial intelligence-based motion analysis (OpenPose) and evaluates the effects of a targeted exercise intervention (FUNBALL).
- Trial name
- NCT07650006
- Testing
- FUNBALL Prevention Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Alcohol Prevention, Mental Health
Feasibility and Effectiveness of Gamified Digital Intervention to Prevent Alcohol and Mental Health Risks
This study evaluates the impact of a novel smartphone application on alcohol consumption, alcohol-related problems, and psychological well-being.
- Trial name
- NCT07546604
- Testing
- Gamified Social App Supporting Womens' Health & Well-being, Psychoeducational Resource Library Access Only
- Where
- United States
- Volunteers
- 1,752 people, healthy volunteers welcome
- Sponsor
- Loyola Marymount University
Violence, Non-accidental
Violence Prevention Study for Youth Age 10-15
This study will evaluate the effectiveness of a hospital-community based violence prevention pilot study designed to increase protective factors and reduce negative risk factors associated with violence of children aged 10-15.
- Trial name
- NCT02393092
- Testing
- Brief Violence Awareness, Brief Violence Prevention, Emerging Leaders: East End curriculum
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Virginia Commonwealth University
Accidental Fall
Evaluating the Cost Effectiveness of STEADI
Stopping Elderly Accidents, Deaths, and Injuries (STEADI) is an intervention to prevent falls among older adults developed by the Centers for Disease Control \& Prevention (CDC).
- Trial name
- STEADI (NCT05390736)
- Testing
- Gait and balance assessment, Medication review, Comorbidity review
- Where
- United States
- Volunteers
- 780 people
- Sponsor
- National Opinion Research Center
Colorectal Cancer Metastatic, Peritoneal (Metastatic) Cancer
Lubiprostone Combined With Maintenance Therapy for Prevention of Postoperative Recurrence in Peritoneal Metastatic Colorectal Cancer
The goal of this phase II randomized controlled clinical trial is to evaluate whether adding lubiprostone to standard postoperative maintenance therapy can delay disease progression and recurrence in adult patients with…
- Conditions
- Colorectal Cancer Metastatic, Peritoneal (Metastatic) Cancer, Peritoneal Metastasis, Colorectal Cancer (CRC)
- Trial name
- NCT07405736
- Testing
- maintenance therapy plus lubiprostone, maintenance therapy
- Volunteers
- 124 people
- Sponsor
- Sun Yat-sen University
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