Clinical trials: Prilocaine
Anesthetic Effectiveness
Testing the Anesthetic Effectiveness of Three Different Dental Local Anesthetics Injected Next to a Lower First Molar
Infiltration (injecting next to the tooth) injections are common in dentistry and a number of studies have shown that articaine anesthetic, when injected next to the tooth as a supplemental injection, works very well following a…
- Trial name
- NCT01567839
- Testing
- Mandibular buccal Infiltration injection
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Anesthesia, Spinal, Prilocaine
Prilocaine for Spinal Anesthesia in Ambulatory Setting
The purpose of this study is to retrospectively analyze data from more than 3000 procedures, to better define the safety profile of spinal prilocaine and the incidence of complications and side effects.
- Conditions
- Anesthesia, Spinal, Prilocaine, Ambulatory Surgical Procedures
- Trial name
- NCT04161586
- Testing
- Prilocaine Hydrochloride
- Where
- Italy
- Volunteers
- 3,291 people
- Sponsor
- Ospedale di Circolo - Fondazione Macchi
Pain
Lidocaine-Prilocaine (EMLA) Cream as Analgesia in Hysteroscopy Practice
The purpose of this study is to demonstrate that Lidocaine-Prilocaine cream decrease pain during hysteroscopy diagnostic practice.
- Trial name
- HISTEROS-07 (NCT01094015)
- Testing
- lidocaine-prilocaine cream, gel application for the transmission of ultrasound
- Where
- Spain
- Volunteers
- 92 people
- Sponsor
- Consorci Sanitari de Terrassa
Knee Arthroscopy, Spinal Anesthesia
Comparison of Hyperbaric Prilocaine With Chloroprocaine for Intrathecal Anaesthesia in Day Case Knee Arthroscopy
This study compares intrathecal 1% plain chloroprocaine with intrathecal 2% hyperbaric prilocaine for patients undergoing ambulatory knee arthroscopy in terms of efficacy and side effects
- Trial name
- NCT03038958
- Testing
- Isobaric 2-chloroprocaine, Hyperbaric prilocaine
- Where
- 2 sites in Belgium
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Blood Pressure Control
Prilocaine for Sphenopalatine Ganglion Block in Endoscopic Hypophysectomy
Patients undergoing endoscopic surgeries for pituitary adenoma excision suffer from wide swings in blood pressure that might increase bleeding and interfere with the surgical field.
- Trial name
- NCT07188987
- Testing
- Sphenopalatine Ganglion Block using 2% lidocaine, Sphenopalatine Ganglion Block
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Kasr El Aini Hospital
Premature Ejaculation
Silicone Band Versus Prilocaine Spray for Lifelong Premature Ejaculation
This pilot study compared two approaches for men with lifelong premature ejaculation, a condition in which ejaculation occurs sooner than desired from the first sexual experiences and is difficult to delay.
- Trial name
- NCT07820865
- Testing
- Frenular Silicone Band, Prilocaine 10% Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Anesthetics, Local
EMLA Cream in Hysteroscopy Practice
The aim of this study is to investigate the efficacy of 5% lidocaine 25 mg-prilocaine 25 mg/g cream (EMLA®) applied to the uterine cervix for reducing pain during diagnostic hysteroscopy, using a visual analogue scale (VAS) for…
- Trial name
- NCT02640183
- Testing
- EMLA
- Volunteers
- 184 people
- Sponsor
- Ain Shams Maternity Hospital
Healthy
Clinical Characteristics of Prilocaine for Spinal Anesthesia in Ambulatory Surgery: Clinical Profile and Efficacy
Introduction: Hyperbaric prilocaine is widely used internationally for outpatient orthopedic and perineal surgery because of its favorable recovery profile compared with other intermediate-acting local anesthetics, such as…
- Trial name
- Prilocaine (NCT07661628)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Local Anesthesia, Pain, Postoperative
EMLA Topical Anesthetic During Scaling and Root Planing
Injectable anesthesics previous to subgingival scaling and root planing (SRP) presents some disadvantages like fear of the needle insertion, long-lasting effect and prolonged dampening of adjacent tissues.
- Conditions
- Local Anesthesia, Pain, Postoperative, Self-Perception
- Trial name
- NCT01860235
- Testing
- EMLA, Injectable anesthesia, 2% Benzocaine
- Volunteers
- 32 people
- Sponsor
- Franciscan University Center
Hernia, Inguinal
Spinal Versus Local Anesthesia for Hernia Repair
patients underwent inguinal hernia repair; Group A patients received Subarachnoid anesthesia; Group B Patients underwent surgery with local anesthesia (Mepivacaine 2%) performed by the surgeon; Pain assessment was performed using…
- Trial name
- SPINOFAST (NCT05136534)
- Testing
- spinal anesthesia, local anesthesia
- Where
- Italy
- Volunteers
- 132 people
- Sponsor
- Campus Bio-Medico University
Methemoglobinemia
Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Local Anesthetics
To establish and compare maximum methemoglobin blood levels and times to maximum methemoglobin blood levels following the administration of the injectable local anesthetics prilocaine and lidocaine when used for dental treatment…
- Trial name
- NCT01402869
- Testing
- 4% prilocaine plain, 2% Lidocaine with 1:100,000 epinephrine
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Knee Arthroscopy (for Diagnostic or Therapy), Inguinal Hernia Repair (Not Urgent)
Selective Subarachnoid Anesthesia. Comparison of Hyperbaric Bupivacaine and Hyperbaric Prilocaine
Selective spinal anesthesia is widely used for ambulatory surgery. Unilateral spinal anesthesia is a suitable option for ambulatory anesthesia as it is efficient and effective.
- Trial name
- BUPIPRILO-07 (NCT01921231)
- Testing
- Hyperbaric Prilocaine 1%, Hyperbaric bupivacaine 0.5%
- Where
- Spain
- Volunteers
- 119 people
- Sponsor
- Dr. Pere Roura-Poch
Pain
Comparison of Lidocaine-Prilocaine Combination and Vapocoolant for IV Cannulation Pain in the ED
Hypothesis: Lidocaine-Prilocaine Combination is as effective as Vapocoolant in treating IV cannulation pain in the emergency department.
- Trial name
- NCT04473820
- Testing
- Vapocoolant spray, Lidocaine-Prilocaine cream
- Where
- Iran
- Volunteers
- 77 people
- Sponsor
- Tehran University of Medical Sciences
IUD Pain
Lidocaine-prilocaine Cream on IUD Insertion Pain
The purpose of the investigators' study was to evaluate whether cervical lidocaine-Prilocaine cream will improve pain scores compared to placebo.
- Trial name
- NCT02658773
- Testing
- lidocaine-Prilocaine cream
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Improving Quality of Life
Pain Relief During Repair of Postpartum Perineal Tears
The aim of our study is to compare the analgesic effect of topical application of lidocaine-prilocaine cream and lidocaine infiltration during repair of postpartum perineal tears.
- Trial name
- LPPT (NCT02883179)
- Testing
- lidocaine injection, lidocaine-prilocaine cream
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Assiut University
Hemorrhoid, Peri Anal Fistula
Discharge Conditions of Spinal Anesthesia With Heavy Prilocaine-Fentanyl and Heavy Bupivacaine-Fentanyl
In this prospective randomized study the investigators aimed to investigate difference of the duration of spinal anesthesia, discharge times and efficacy between low dose heavy Prilocaine-Fentanyl and heavy Bupivacaine-Fentanyl…
- Trial name
- NCT01880775
- Testing
- Prilocaine, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Diskapi Teaching and Research Hospital
Spinal Anesthesia
Hyperbaric Prilocaine 2% vs Hyperbaric Bupivacaine 0.5% in Caesarean Section
Comparison between effects of hyperbaric bupivacaine 0.5% vs Hyperbaric prilocaine 2% in spinal anesthesia of women undergoing elective caesarean section such as onset time of sensory and motor block, duration of sensory and…
- Trial name
- NCT06680167
- Testing
- Spinal anesthesia (heavy bupivacaine 0.5%), spinal anesthesia (hyperbaric Prilocaine 2%)
- Where
- Egypt
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Sohag University
Other Surgical Procedures
Ultrasound-guided Axillary Plexus Block - Dose Reduction of Prilocaine
Clinical aim: Does reducing the dose of local anesthetic in ultrasound-guided axillary plexus anesthesia have any effect on the success rate and additional parameters of block quality? Methodology: In this prospective cohort…
- Trial name
- NCT01309360
- Testing
- midazolam, prilocaine 1%
- Volunteers
- 120 people
- Sponsor
- Helios Research Center
Myofacial Pain Syndromes
Does Botulinum Toxin Type-A Injection an Effective Way of Relieving Pain in Myofascial Pain Syndrome Patients or Not
In this research prilocaine and botulinum toxin (BoNT-A) interventions prospectively compared to find out the effect of BoNT-A injection on myofascial pain syndrome (MPS).
- Trial name
- NCT06899438
- Testing
- Botulinum Toxin A Injection, Prilocaine HCl % 2 injectable solution
- Volunteers
- 38 people
- Sponsor
- Bursa City Hospital
Pregnant Women
Estimation of the Effective Dose (ED) 95 of Intrathecal Hyperbaric Prilocaine 2% for Scheduled Cesarean Delivery.
Prilocaine is a local anesthetic drug which as an intermediate duration of action shorter than bupivacaine 0,5% that is usually used for spinal anesthesia in scheduled cesarean section.
- Trial name
- NCT03607916
- Testing
- Hyperbaric prilocaine 2%, Morphine
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre