Clinical trials: Prilocaine
Pain During Intrauterine Device Insertion
The Effectiveness of Topical Prilocaine-Lidocaine Cream Plus Acetaminophen and Naproxen Compared to Lidocaine Injection Plus Acetaminophen and Naproxen to Manage Pain During IntraUterine Device Insertion
The goal of this clinical trial is to learn if two pain medications used to treat pain during intrauterine device insertions work in persons with a uterus. It will also learn about the safety of the two study medications.
- Trial name
- NCT07546370
- Testing
- Prilocaine, Lidocaine, Lidocaine HCl 1%
- Where
- Canada
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Monakshi Sawhney
Contraception, Lidocaine
Pain Relief for Birth Control Implants Insertion
The aim of our study is to compare the analgesic effect of topical application of lidocaine-prilocaine cream and lidocaine infiltration during insertion of birth control implants
- Trial name
- NCT03187392
- Testing
- Lidocaine Injectable Product, Lidocaine Topical Cream [LMX]
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Assiut University
Labor, Induced
Topical Anesthesia During Catheter Insertion for Cervical Ripening (TOLERANCE)
The goal of this RCT is to learn if application of topical anesthetic cream to the perineum and posterior wall of vagina prior to balloon catheter insertion as part of labor induction will reduce pain levels experienced by…
- Trial name
- TOLERANCE (NCT07288021)
- Testing
- Topical Analgesia with Lidocaine-Prilocaine cream
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Bnai Zion Medical Center
Hysterosalpingography
Oral Hyoscine vs Lidocaine-Prilocaine Spray vs Placebo for HSG Pain Relief
This single-centre, three-arm, randomised, double-blind, double-dummy, placebo-controlled trial evaluated the efficacy and safety of oral hyoscine butylbromide, topical lidocaine-prilocaine spray and placebo for reducing pain…
- Trial name
- NCT07383571
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Cairo University
Recruitment
Low Dose Bupivacaine Versus Prilocaine Regarding Hemodynamic Stability and Safety in Geriatrics
Orthopedic interventions under spinal anesthesia is considered a common practice in elderly patients undergo surgery, and may be associated with lower risks of death, delirium,and major medical complications .
- Trial name
- NCT06382220
- Testing
- Bupivacain
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Fayoum University Hospital
Anesthesia, Anesthesia; Reaction
Comparison of Hyperbaric Prilocaine 2% 50 Mg and Hyperbaric Bupivacaine 0.5% 12.5 Mg Against Spinal Anesthesia Recovery Time in Cystoscopy Procedure
Data regarding the comparison of recovery time from spinal anesthesia between prilocaine and bupivacaine are still relatively limited.
- Trial name
- NCT05610007
- Testing
- Prilocaine
- Where
- Indonesia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Knee Replacement, Total, Knee Replacement Surgery
Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine in Spinal Anaesthesia
Prilocaine numbs you for a shorter time, allowing you to regain movement quicker, which helps you recover faster, start rehab sooner, and feel more satisfied with your treatment overall.
- Trial name
- NCT07329582
- Testing
- prilocaine, Bupivacaine
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- National University Hospital, Singapore
Overcoming the Failure of Anaesthesia, Maxillary Teeth
Comparison of Articaine and Prilocaine for Extraction of Maxillary Teeth
Ninety-five patients, aged between 16 and 70 years old, were included in this study. Patients were divided into two groups. Group one received Articaine 4% with 1:00.000 Adrenalines.
- Conditions
- Overcoming the Failure of Anaesthesia, Maxillary Teeth, Dental Extraction
- Trial name
- NCT04236115
- Testing
- Articaine 4%, Prilocain 3%, Adrenalin
- Where
- Saudi Arabia
- Volunteers
- 95 people
- Sponsor
- Taibah University
Postherpetic Neuralgia
Study of NGX-4010 With the Use of Open Label Lidocaine (2.5%)/Prilocaine (2.5%) Cream for the Treatment of Postherpetic Neuralgia (PHN)
This study is an open-label multi-center to evaluate the tolerability of treatment with NGX-4010 use with pre-patch topical application of a topical anesthetic cream. This is an open-label study.
- Trial name
- NCT00916942
- Testing
- capsaicin 8%, Lidocaine (2.5%)/Prilocaine (2.5%) Cream
- Where
- 6 sites in United States
- Volunteers
- 20 people
- Sponsor
- NeurogesX
Post Operative Pain
Lidocaine-Prilocaine Cream (EMLA) Topical Application Versus Wound Infiltration With Lidocaine After Cesarean Section
A Comparison Between Lidocaine-Prilocaine Cream (EMLA) Application And wound Infiltration with Lidocaine For Post Caesarean Section Pain Relief : A Randomized Controlled Trial.
- Trial name
- NCT02549105
- Testing
- EMLA CREAM 5 mg, LIDOCAINE 1 %
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Dental Trauma, Local Anesthesia
Clinical Efficiency of Xanthan Hydrogels Containing Local Anesthetics Encapsulated in Nanostructured Lipid Carries
In a crossover, randomized, placebo-controlled, double-blind study, 40 volunteers will receive the following formulations: hydrogels containing LAs (local anesthetic) - lidocaine and prilocaine (both at 2.5%) encapsulated in CLN…
- Conditions
- Dental Trauma, Local Anesthesia, Oral Cavity Disease
- Trial name
- NCT05912335
- Testing
- Topical anesthetic
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Postoperative Shivering
Spinal Anesthesia With Bupivacaine Versus Prilocaine on Postoperative Shivering After Inguinal Hernia Repair
Effect of spinal anesthesia with bupivacaine versus prilocaine on postoperative shivering after inguinal hernia repair : a prospective randomized double blind study
- Trial name
- NCT07564180
- Testing
- Bupivacaine Spinal Anesthesia, Prilocaine spinal anesthesia, Spinal Anesthesia (bupivacaine) spinal anesthsia (prilocaine)
- Volunteers
- 80 people
- Sponsor
- Amr mohamed
Post Operative Pain
Intrathecal Prilocaine and Adductor Canal Block vs Intrathecal Bupivacaine Alone for Ambulatory Knee Arthroscopy
Although bupivacaine is safe and has a low rate of transient neurologic symptoms, the prolonged sensory and motor block is a drawback for day-case spinal anesthesia.Intrathecal hyperbaric prilocaine causes a much shorter motor…
- Trial name
- NCT05609565
- Testing
- spinal anesthesia with hyperbaric prilocaine+adductor canal block (ACB) with bupivacaine, spinal anesthesia with bupivacaine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Topical Anesthesia
Pharmacokinetic Study of Nanoencapsulated Gel of Lidocaine, Prilocaine and Combination of Lidocaine and Prilocaine
This trial evaluated the pharmacokinetic interaction between fixed doses of lidocaine (2.5%), prilocaine (2.5%) or the association of both (Nanorap®) in healthy volunteers. The drug safety and tolerability was also evaluated.
- Trial name
- NCT03441841
- Testing
- Lidocaine + Prilocaine, Lidocaine, Prilocaine
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Galeno Desenvolvimento de Pesquisas Clínicas
Pain
Lidocaine-Prilocaine Cream in Conjunction With Paracervical Block for Pain With Abortion
The investigators theorize that the application of a lidocaine-prilocaine cream 5-10 minutes prior to the administration of a paracervical block could decrease pain associated with its administration and pain with abortion…
- Trial name
- NCT03508804
- Testing
- Lidocaine-Prilocaine Cream, 1% Lidocaine Paracervical Block
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Plantar Warts
Efficacy Trial of Eutectic Lidocaine/Prilocaine Cream 5% (EMLA) for Analgesia Prior to Cryotherapy of Verrucae Plantaris
Aims: The investigators main purpose is to assess the efficacy of analgesia provide by topical lidocaine/prilocaine cream 5% (EMLA)® to pared plantar warts prior to application of liquid nitrogen cryotherapy in adults.
- Trial name
- NCT01330615
- Testing
- EMLA
- Where
- Singapore
- Volunteers
- 64 people
- Sponsor
- National University Hospital, Singapore
Gynecological Pathology
Lidocaine-Prilocaine (EMLA) Cream as Analgesia in Hysterosalpingography Practice
The purpose of this study is to demonstrate that Lidocaine-Prilocaine cream decrease pain during hysterosalpingography diagnostic practice.
- Trial name
- HSG-2010 (NCT01303614)
- Testing
- Lidocaine-Prilocaine cream
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Consorci Sanitari de Terrassa
Myofacial Pain, Pelvic Pain
Lidocaine-prilocaine Cream as Analgesia for In-office Levator Muscle Trigger Point Injections
Levator muscle trigger point injections (TPI) are a commonly performed procedure in the office for treatment of pelvic pain related to pelvic floor muscles. The most common concern related to in-office TPI is pain.
- Trial name
- NCT07778043
- Testing
- Lidocaine-Prilocaine Cream 2.5-2.5%, Permeation-enhancing vanishing cream
- Volunteers
- 36 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Chronic Leg Ulcer
Efficacy of 50% Nitrous Oxide/50% Oxygen Gas Premix in Chronic Leg Ulcer Debridement
Adequate analgesia in serial chronic leg ulcer debridement can be difficult to achieve. A common analgesia method is the topical administration of local anesthetics directly onto the wound.
- Trial name
- NCT02696460
- Testing
- N2O/O2 analgesia, Lidocaine/Prilocaine analgesia
- Volunteers
- 21 people
- Sponsor
- Venenklinik Bellevue
Pain, Needle Phobia
The Efficacy of EMLA Cream vs. Synera Patch for Pain Reduction During Venipuncture in Children
This study compares the efficacy of the Synera patch with Eutectic Mixture of Local Anesthetics (EMLA) as a topical anesthetic for venipuncture in pediatric patients.
- Trial name
- NCT00530803
- Testing
- EMLA Cream, Synera Patch
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Montefiore Medical Center