Clinical trials: Primary
Silver Diamine Fluoride
Long-term Effect of Silver Diamine Fluoride on the Dentin-Pulp Complex in Primary Teeth
Children with primary teeth with dentin carious lesions without pulp involvement, who have previously been treated with either Silver Diamine Fluoride (SDF) followed by Resin Modified Glass Ionomer or with Resin Modified Glass…
- Trial name
- NCT07586631
- Where
- Egypt
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Cairo University
Amyotrophic Lateral Sclerosis, Primary Lateral Sclerosis
Digital Assessment of Speech and Fine Motor Control in ALS
This is a single-session, case-control study that incorporates digital tools for assessing speech and motor function in motor neuron disease.
- Conditions
- Amyotrophic Lateral Sclerosis, Primary Lateral Sclerosis, Progressive Muscular Atrophy
- Trial name
- NCT06315673
- Testing
- Digital Speech and Handwriting Assessment
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Long Covid19, Autonomic Dysfunction
Autonomic Nervous System Affection Due to Post Covid Syndrome
Post-Covid syndrome is defined as symptoms that develop in addition to respiratory symptoms in individuals who have had Covid-19 infection for more than 12 weeks.
- Trial name
- NCT05502094
- Testing
- Heart Rate Variability Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Peripheral Arterial Disease
Education and Management of PAD in Primary Care
Peripheral arterial disease (PAD) occurs when the vessels carrying blood to the legs become narrowed or blocked. It affects 1 in 5 people aged over 60 and are at risk of losing their leg, developing a heart attack or stroke, or…
- Trial name
- NCT04342481
- Testing
- Educational Screening tool
- Where
- United Kingdom
- Volunteers
- 891 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Migraine
Staccato Loxapine in Migraine (in Clinic)
The objective of this trial is to assess the efficacy and safety of Staccato Loxapine in patients with migraine headache with or without aura in a clinical setting.
- Trial name
- NCT00489476
- Testing
- Staccato Loxapine
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Alexza Pharmaceuticals, Inc.
Childhood Obesity, Family
FamCe-HLP- Family-centered Obesity Management Program in Primary Care Settings
This clinical trial aims to compare the adiposity and weight status among mother-child dyads with overweight or obesity who receive the Fam-Ce-HLP intervention with the mother-child dyads with overweight or obesity who did not…
- Conditions
- Childhood Obesity, Family, Behavior, Health, Lifestyle, Healthy
- Trial name
- NCT06394882
- Testing
- Family-Centered Healthy Lifestyle Program (FamCe-HLP)
- Where
- 4 sites in Oman
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oman Ministry of Health
Hyperopia, Long Sight
Zimbabwe Eyecare And Learning(ZEAL):Formative Research on Hyperopia and Educational Outcomes in Primary School Children
The purpose of this study is to determine whether uncorrected or corrected long-sightedness (hyperopia) has an impact on reading skills, in Grade 2 or Grade 4 school-aged children from Mashonaland Central province of Zimbabwe…
- Trial name
- ZEAL (NCT05538182)
- Testing
- Spectacles
- Where
- Zimbabwe
- Volunteers
- 1,883 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Lung Neoplasms
TELESCOPE- TELEhealth Shared Decision-making COaching
Hypothesis 1a: The investigators anticipate that navigator decision coaching, compared to enhanced usual care (EUC) will result in higher quality SDM for lung cancer screening (LCS )(primary outcome), greater knowledge of lung…
- Trial name
- NCT05491213
- Testing
- TELESCOPE, Remote Decision Coaching with Navigation Intervention
- Where
- 2 sites in United States
- Volunteers
- 594 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Sleep Bruxism, Tension Headache
Treatment Sleep Bruxism With the Luco Hybrid OSA Appliance
To determine the effectiveness of the Luco Hybrid OSA Appliance in the treatment of sleep bruxism and to aid in the treatment of associated tension/migraine type headaches in adults.
- Conditions
- Sleep Bruxism, Tension Headache, Migraine Headache
- Trial name
- LucoHybrid (NCT02882880)
- Testing
- The Luco Hybrid OSA Appliance
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Luco Hybrid OSA Appliance Inc.
Opioid Dependence
XRB vs. SLB in Jail and at Re-entry: Pilot, Proof of Concept
This is a pilot proof-of-concept randomized controlled trial, open-label and unblinded, examining the feasibility and acceptability of Buprenorphine extended-release vs.
- Trial name
- NCT03604159
- Testing
- Buprenorphine Extended Release, Sublingual Buprenorphine (SUBOXONE, Zubsolv, or generic tablets)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Cesarean Section
Risk Factors for Primary Cesarean Section in Egypt
women in their first pregnancy evaluated till delivery for associated risk factors for cesarean delivery
- Trial name
- NCT03905980
- Testing
- vaginal delivery, Cesarean section
- Where
- Egypt
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acupressure
The Effect of Acupressure and Massage on Pain in Primary Dysmenorrhea
Painful menstrual bleeding, also known as dysmenorrhea, is one of the common gynecological ailments that have health, social, and economic implications.
- Trial name
- NCT04942288
- Testing
- The first group is acupressure and massage, the second group is massage
- Where
- Turkey (Türkiye)
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Inonu University
Tobacco Use Cessation
Comparative Effectiveness of Mobile Health Smoking Cessation Approaches Among Underserved Patients in Primary Care
This study will evaluate the comparative effectiveness of three smoking cessation therapies: mobile health (mHealth) application iCanQuit, mHealth application iCanQuit + Motiv8, and the Florida quit line.
- Trial name
- PROMOTE-UP (NCT05415761)
- Testing
- iCanQuit, iCanQuit+Motiv8, Florida quit line
- Where
- United States
- Volunteers
- 1,332 people, healthy volunteers welcome
- Sponsor
- University of Florida
Primary Sclerosing Cholangitis
A Study of HTD1801 in Healthy Subjects
This is a randomized, double blind, single center, ascending single dose study to evaluate the safety, tolerability, and PK of HTD1801.
- Trial name
- NCT03099603
- Testing
- HTD1801
- Where
- Australia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- HighTide Therapeutics (Hong Kong) Limited
Healthy Lifestyle
Promotion of Healthy Lifestyle Habits in Primary Care Settings
Intervention aiming to promote healthy dietary and physical activity behaviors in adults with different socioeconomic status primary care settings
- Trial name
- PCrorelse (NCT05689762)
- Testing
- Healthy lifestyle counseling and E-health support
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Insomnia
Agewise Project 3: Brief Behavioral Treatment of Insomnia in Primary Care
This project will test the efficacy of a brief, 2 session behavioral intervention for insomnia, as compared to an information-only condition.
- Trial name
- AW3 (NCT00177203)
- Testing
- Brief Behavioral Treatment of Insomnia or Information
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pain Assessment
Effect of Starpen CCLAD in Injection and Extraction
The present study aims to evaluate the effect of computer-controlled Starpen automatic injection device versus the traditional syringe on pain perception during Injection of nerve block anesthesia and extraction of mandibular…
- Trial name
- Starpen CCLAD (NCT06827223)
- Testing
- computer-controlled Starpen Automatic Injection Device, Traditional Syringe
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
COVID-19
Study of Recombinant Protein Vaccines With Adjuvant as a Primary Series and as a Booster Dose Against COVID-19 in Adults 18 Years of Age and Older
The primary objectives of the study are: To assess the safety profile of the study vaccines in each study intervention group. To assess the neutralizing antibody profile after primary series vaccination in SARS-CoV-2-naïve…
- Trial name
- NCT04762680
- Testing
- SARS-CoV-2 recombinant protein vaccine Phase 2 Formulation 1, SARS-CoV-2 recombinant protein vaccine Phase 2 Formulation 2, SARS-CoV-2 recombinant protein vaccine Phase 2 Formulation 3
- Where
- 66 sites in United States, Australia and 5 more
- Volunteers
- 3,159 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Primary Ovarian Insufficiency, Vaginitis
A Study To Compare The Amount Of Premarin Components That Is Absorbed Into The Blood Of Japanese Healthy Postmenopausal Women Following Oral Administration Of Two Different Tablets Of Premarin Under Fast and Fed Conditions.
The purpose of this study is to assess the bioequivalence and food effect for a new Premarin formulation compared with a Premarin reference tablet in Japanese healthy postmenopausal women.
- Conditions
- Primary Ovarian Insufficiency, Vaginitis, Metrorrhagia, Menopause
- Trial name
- NCT01436513
- Testing
- Premarin reference tablet (fasted), Premarin new tablet (fasted), Premarin reference tablet (fed)
- Where
- Japan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Pfizer
Orthostatic Hypotension, Syncope
The Effect of Water Carbonation on Orthostatic Tolerance
The primary purpose of this investigation is to determine whether water carbonation can improve orthostatic tolerance in healthy control volunteers.
- Conditions
- Orthostatic Hypotension, Syncope, Vasovagal Syncope
- Trial name
- NCT05621460
- Testing
- 500mL carbonated water, 500mL still water, 50mL still water
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
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