Clinical trials: Primary
Tension-Type Headache, Trigger Points
Trigger Point Dry Needling for Chronic Tension-Type Headache
In this double-blind randomized trial, we aimed to explore the effectiveness of trigger point dry needling in patients with chronic tension type headache (CTTH) in reduction of headache frequency, intensity, duration, and…
- Trial name
- NCT03500861
- Testing
- Dry Needling
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Eastern Mediterranean University
Migraine Headache
Randomized Evaluation of Octreotide Versus Compazine for Emergency Department Treatment of Migraine Headache
: Headaches are a common complaint presenting to the emergency department (ED), accounting for 1-2% of all ED visits, with migraines as the second most common primary headache syndrome.
- Trial name
- NCT00274170
- Testing
- Octreotide
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- C.R.Darnall Army Medical Center
Primary Dysmenorrhea
Effect of Mojzisova Method on Pain, Menstrual Symptom and Insomnia in PD
This project was a Randomized controlled trial conducted to check the effectiveness of mojzisova method in primary dysmenorrhea for pain, menstrual symptoms and insomnia.
- Trial name
- NCT06460870
- Testing
- Mojzisova method, Stretching exercises
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Nasopharyngeal Carcinoma, Intensity-Modulated Radiotherapy
Reducing High Risk Primary Tumor Clinical Target Volumes (CTVp1) in Non-metastatic Nasopharyngeal Carcinoma
To evaluate the long-term local control, survival rate, acute and late radiation related toxicities, quality of life after reducing high risk primary tumor clinical target volumes (CTVp1) in non-metastatic nasopharyngeal…
- Trial name
- CTVp1-NPC (NCT05994170)
- Testing
- Reduction CTVp1, Non-reduction CTVp1
- Where
- China
- Volunteers
- 454 people
- Sponsor
- Zhongshan People's Hospital, Guangdong, China
ST Elevation Myocardial Infarction, Myocardial Infarction
OCT Versus Angiography for Culprit Lesion Revascularization in Acute Myocardial Infarction PatiEnts
The aim of the study is to compare clinical outcomes between optical coherence tomography-guided versus angiography-guided percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI).
- Trial name
- FRAME-AMI3 (NCT06227754)
- Testing
- Angiography-guided PCI group, Optical coherence tomography-guided PCI group
- Where
- 18 sites in South Korea
- Volunteers
- 1,500 people
- Sponsor
- Chonnam National University Hospital
Ovarian Cancer, Fallopian Tube Carcinoma
Neoadjuvant Chemotherapy in Epithelial Ovarian Cancer
The purpose of this study is to define whether 6 courses of neoadjuvant chemotherapy can lead to a higher rate of complete cytoreductive surgery compared with 3 courses of neoadjuvant chemotherapy in patients with epithelial…
- Conditions
- Ovarian Cancer, Fallopian Tube Carcinoma, Peritoneal Carcinoma
- Trial name
- GOGER-01 (NCT02125513)
- Testing
- carboplatin and paclitaxel followed by surgery
- Where
- 5 sites in Italy
- Volunteers
- 129 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Deep Vein Thrombosis
Destiny: D-dimer. Investigating D-dimer Levels Using Point-of-Care (POC) Testing at Primary Care.
DESTINY D-Dimer is an observational feasibility study, and a collaboration between the University of South Wales and Cwm Taf Morgannwg University Health Board (CTMUHB). The study is based at St.
- Trial name
- Destiny (NCT05109260)
- Testing
- Point-of-Care Immunoassay device
- Where
- 2 sites in United Kingdom
- Volunteers
- 244 people
- Sponsor
- University of South Wales
Granulomatous Disease, Chronic, Job's Syndrome
Posaconazole to Treat Invasive Fungal Infections
This study will evaluate the safety and effectiveness of posaconazole for treating invasive fungal infections. New therapies for these infections are needed for patients who do not respond, to or cannot tolerate, standard…
- Conditions
- Granulomatous Disease, Chronic, Job's Syndrome, Infection
- Trial name
- NCT00033982
- Testing
- Posaconazole
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Myelofibrosis
Myelofibrosis Treated With Pacritinib Before aSCT. (HOVON134MF)
The only curative treatment for patients with myelofibrosis (MF) is allogeneic stem cell transplantation (SCT). Treatment with JAK2 inhibitors like pacritinib improves condition of MF patients, decreases spleen size and might…
- Trial name
- HOVON134MF (NCT03645824)
- Testing
- Pacritinib
- Where
- 12 sites in Belgium, Netherlands
- Volunteers
- 61 people
- Sponsor
- Stichting Hemato-Oncologie voor Volwassenen Nederland
Lactation
Recombinant Human Prolactin for Lactation Induction
The purpose of the study is to assess the safety and determine the effects of the hormone prolactin on lactation (breast milk production).
- Trial name
- NCT00181623
- Testing
- Recombinant Human Prolactin
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital
Chronic Optic Neuropathy in Multiple Sclerosis
CHRONIC OPTIC NEUROPATHY IN MULTIPLE SCLEROSIS
Patients with multiple sclerosis (MS) may show chronic signs of optic neuropathy (CON) that may follow acute optic neuritis (secondary form of CON, S-CON) or occur independently of any acute demyelinating lesion of the optic…
- Trial name
- NCT02543788
- Testing
- • Neuro-Ophthalmological examination, Visual Acuity, Fundus, Visual Field, Color Vision, OCT, EDSS • NEI-VFQ 25 and the 10-item • VEPs, p-ERG and mf-ERG
- Where
- France
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Health Services for the Aged, Medication Therapy Management
A New Interdisciplinary Collaboration Structure to Improve Medication Safety in the Elderly
Suboptimal use of medications among geriatric patients is well-known problem and leads to medication errors, re-hospitalizations and death.
- Trial name
- IMMENSE (NCT02816086)
- Testing
- Interdisciplinary collaboration structure
- Where
- Norway
- Volunteers
- 516 people
- Sponsor
- University of Tromso
Sarcopenia, Sjogren's Syndrome
Prevalence and Factors of Sarcopenia and in Patients With Primary Sjogren's Syndrome
Sarcopenia is a progressive condition characterized by decline in muscle strength and muscle mass. Although the mechanism of sarcopenia has not been fully elucidated, it may be caused by protein-poor diet, vitamin D deficiency…
- Conditions
- Sarcopenia, Sjogren's Syndrome, Rheumatologic Disease
- Trial name
- NCT05015114
- Testing
- Sarcopenia Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Acibadem University
Liver Cancer
Sunitinib and Chemoembolization in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery
RATIONALE: Sunitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
- Trial name
- NCT00524316
- Testing
- doxorubicin hydrochloride, sunitinib malate, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Roswell Park Cancer Institute
Tonsillitis, Streptococcus Pharyngitis
Antimicrobial Stewardship Program (ASP) in Patients With a Sore Throat
The investigators have developed an antibiotic stewardship program (ASP) to increase adherence to the Swedish guidelines for managing patients with a sore throat.
- Conditions
- Tonsillitis, Streptococcus Pharyngitis, Sore Throat, Pharyngitis
- Trial name
- ASP-Throat (NCT03408704)
- Testing
- ASP
- Where
- Sweden
- Volunteers
- 49 people
- Sponsor
- Vastra Gotaland Region
Membranoproliferative Glomerulonephritis
Eculizumab in Primary MPGN
Membranoproliferative glomerulonephritis (MPGN) is the third or fourth leading cause of end stage renal disease among the primary glomerulonephritis.
- Trial name
- EAGLE (NCT02093533)
- Testing
- Eculizumab
- Where
- 13 sites in Italy
- Volunteers
- 10 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Anxiety
Moving on! A Tailored Treatment in a Primary Care Setting for Individuals With Anxiety Disorders?
The goal of this clinical study is to investigate the effects of two different interventions in patients with anxiety disorder and who seeks help at primary care centers. The participants will choose between two interventions: 1.
- Trial name
- NCT06715852
- Testing
- PHYSBI: a 12-week physical exercise program, Modified eHealth Lift: a digital, evidence based lifestyle-intervention for health promotion.
- Where
- Sweden
- Volunteers
- 450 people
- Sponsor
- Vastra Gotaland Region
Treatment Related Cancer
Pancreatic Cyst Ablation With a Monopolar Radiofrequency Ablation Probe
Pancreatic cysts (A cyst is a thin walled cavity containing fluid) were rarely reported previously, but have been on a rise due to advanced imaging for evaluating pancreatic lesions or other medical reasons has increased…
- Trial name
- NCT04253249
- Where
- United States
- Sponsor
- Baylor College of Medicine
Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11
Lenalidomide After Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancers
This phase I clinical trial is studying the side effects and the best dose of lenalidomide after donor bone marrow transplant in treating patients with high-risk hematologic cancer.
- Conditions
- Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11, Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11, Adult Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1
- Trial name
- NCT01254578
- Testing
- Laboratory Biomarker Analysis, Lenalidomide, Pharmacological Study
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Cancer Institute (NCI)
Bladder Function
Pilot Trial in Sleep Laboratory Setting to Compare the Physiology of Night Time Bladder Function in Subjects With Overactive Bladder (OAB) Versus Subjects That Have Insomnia and Healthy Normal Subjects
This is an observational, physiology pilot study of subjects with overactive bladder, insomnia and normal subjects. No study drug will be given. All subjects will complete a one week sleep diary and a 3-day bladder diary.
- Trial name
- Nocturia Plt 1 (NCT01029015)
- Testing
- cystometry, polysomnography
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
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