Clinical trials: Primary Angioplasty
Acute Myocardial Infarction
Primary Angioplasty for Acute Myocardial Infarction in Patients With Symptom Duration Above 12 Hours
Background: Acute balloon angioplasty is beneficial in patients with acute myocardial infarction. However, presently this treatment is not offered to patients with symptom duration above 12 hours.
- Trial name
- NCT00260416
- Testing
- Primary angioplasty with stent and abciximab
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Aarhus University Hospital Skejby
Myocardial Infarction
Optimizing Infarct Size by Transforming Emergent Stenting Into an Elective Procedure Study
The goal of primary PCI is to restore anterograde myocardial flow. Stenting a largely thrombotic lesion may determine distal embolisation of thrombotic material therefore deteriorating myocardial perfusion.
- Trial name
- OPTIMASTRATEGY (NCT01462188)
- Testing
- Immediate stenting, Delayed stenting
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Marco Valgimigli
Acute Myocardial Infarction
FATA: Randomized Study on Facilitated Angioplasty With Tirofiban or Abciximab
The elective("standard of care") treatment of ST - elevation acute myocardial infarction (STEMI) currently consists of primary angioplasty with stent implantation during administration of Abciximab, a inhibitor of GP IIb/IIIa…
- Trial name
- FATA (NCT00383136)
- Testing
- tirofiban high-bolus dose regimen, Abciximab
- Where
- 6 sites in Italy
- Volunteers
- 692 people
- Sponsor
- University of Bologna
Coronary Artery Disease
STRATEGY for Left Main Coronary Bifurcation Lesion II
In patients with unprotected left main (LM) true bifurcation lesion (cohort A), elective 2-stent strategy is superior to provisional strategy at preventing the occurrence of 12-month target lesion failure after percutaneous…
- Trial name
- STRATEGY-II (NCT01798433)
- Testing
- One stent technique alone, One stent technique + Elective FKB, Provisional approach
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Coronary Disease, Hypercholesterolemia
Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome (JAPAN-ACS)
The purpose of this study is to compare the effects of pitavastatin and atorvastatin on coronary plaque volume in patients with acute coronary syndrome and to clarify the relationship between coronary plaque volume, serum lipids…
- Trial name
- NCT00242944
- Testing
- Pitavastatin, Atorvastatin
- Where
- 3 sites in Japan
- Volunteers
- 307 people
- Sponsor
- Kyoto University
Primary Angioplasty
Evaluation of Feasibility of Radial Access for Primary Angioplasty and to Assess it in High Risk Subgroups
Primary percutaneous coronary intervention is the preferred treatment for patients with ST-segment acute coronary syndrome. The radial access is an established approach, associated with a reduction in vascular access related…
- Trial name
- NCT03488407
- Volunteers
- 315 people
- Sponsor
- Jubilee Mission Medical College and Research Institute
ST-elevation Myocardial Infarction
Primary Reperfusion Secondary Stenting Trial
The purpose of this research project is to improve how we treat heart attacks. The study will assess whether it might not be better to wait a few hours before implanting the coronary stent into the coronary artery rather than…
- Trial name
- PRIMACY (NCT01542385)
- Testing
- Stent
- Where
- 16 sites in Canada, France
- Volunteers
- 307 people
- Sponsor
- Montreal Heart Institute
Myocardial Infarction
Nitroprusside for Prevention of no-Reflow in Primary Angioplasty
In patients admitted with acute myocardial infarction, there is a total occlusion of a coronary artery. Even after emergency catheterization and angioplasty, in some patients, the resumed blood flow is suboptimal and impacts on…
- Trial name
- NCT00128791
- Testing
- Nitroprusside
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Soroka University Medical Center
Coronary Artery Disease
Stenting With or Without Coating Compared With Angioplasty in Non-benestent Disease
The purpose of this study is to evaluate the clinical and angiographic outcome of implantation of stents eluting or not eluting Sirolimus in patients with complex coronary artery lesions suitable for percutaneous coronary…
- Trial name
- NCT00192881
- Testing
- Bx Sonic & Cypher stent from Cordis
- Where
- Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cardiovascular Disease, Myocardial Infarction
A Prospective, Randomized Trial of BVS Veruss EES in Patients Undergoing Coronary Stenting for Myocardial Infarction
The aim of the current study is to test the clinical performance of the everolimus-eluting BVS compared with that of the durable polymer everolimus-eluting stent (EES) in patients undergoing PCI in the setting of acute MI.
- Conditions
- Cardiovascular Disease, Myocardial Infarction, Thrombus, Primary Angioplasty
- Trial name
- ISAR-Absorb MI (NCT01942070)
- Testing
- Bioresorbable vascular scaffold, Durable polymer everolimus-eluting metallic stent
- Where
- 2 sites in Germany
- Volunteers
- 262 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Myocardial Infarction
Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction
The primary objectives of the trial are: 1. To establish the safety and efficacy of the use of bivalirudin (+ bail-out GP IIb/IIIa inhibitors) compared to the use of unfractionated heparin + GP IIb/IIIa inhibitors in patients…
- Trial name
- NCT00433966
- Testing
- Bivalirudin, Unfractionated heparin, Bare metal stent
- Where
- United States
- Volunteers
- 3,602 people
- Sponsor
- Cardiovascular Research Foundation, New York
ST Elevated Myocardial Infarction Undergoing Mechanical Reperfusion
Primary Angioplasty for STEMI During COVID-19 Pandemic (ISACS-STEMI COVID-19) Registry
The ISACS STEMI COVID-19 has been established in response to the emerging outbreak of COVID-19 to provide a European overview to estimate the real impact of COVID-19 pandemic on treatment and outcome of STEMI by primary…
- Trial name
- ISACS-STEMI (NCT04412655)
- Testing
- Percutaneous Coronary Revascularization for STEMI
- Where
- Italy
- Volunteers
- 6,609 people
- Sponsor
- Università degli Studi del Piemonte Orientale Amedeo Avogadro
Coronary Artery Disease, Heart Attack
Registry of Non-primary Angioplasty at Hospitals Without Surgery On-site
This is a simple registry of patients undergoing PCI at hospitals without surgery on-site who were participants in the CPORT-E project.
- Conditions
- Coronary Artery Disease, Heart Attack, Angina
- Trial name
- CPORT (NCT02137980)
- Where
- 37 sites in United States
- Volunteers
- 31,390 people
- Sponsor
- Johns Hopkins University
Acute Myocardial Infarction
REgister of Myocardial Infarction Patients Treated by the NOVAra STE-MI Network
Myocardial infarction (MI) outcomes strictly depend on the time to reponed the infarct-related coronary artery. Networks have been activated in the last years in many countries to achieve fast track access of patients with…
- Trial name
- RENOVAMI (NCT01760382)
- Testing
- Primary PCI
- Where
- Italy
- Volunteers
- 700 people
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Acute Myocardial Infarction
Tirofiban Intracoronary Bolus-only Versus Intravenous Bolus Plus Infusion in STEMI Patients
The aim of this randomized trial is to compare the efficacy of high dose tirofiban administered as either an intracoronary bolus alone or as an intravenous bolus followed by a maintenance infusion with respect to microvascular…
- Trial name
- NCT01109134
- Testing
- tirofiban intracoronary bolus-only, tirofiban intravenous bolus plus infusion
- Volunteers
- 49 people
- Sponsor
- Kosuyolu Heart Hospital
Contrast Induced Nephropathy
Hydration and Contrast-Induced Nephropathy in Primary Angioplasty
The purpose of this study is to determine whether hydration with sodium bicarbonate is more effective than hydration with sodium chloride to prevent contrast induced nephropathy in patients undergoing Primary Coronary…
- Trial name
- NCT00770614
- Testing
- sodium bicarbonate solution, Isotonic saline
- Where
- Italy
- Volunteers
- 450 people
- Sponsor
- Ospedale Misericordia e Dolce
Acute Myocardial Infarction
A Study of INO-1001, an Intravenous PARP (Poly [ADP Ribose] Polymerase) Inhibitor in Acute Heart Attack Patients Undergoing Primary Percutaneous Coronary Intervention
The primary purpose of this study is to assess the safety of INO-1001 in subjects who have experienced a heart attack and are to be treated with coronary angioplasty.
- Trial name
- NCT00271765
- Testing
- INO-1001
- Where
- 16 sites in United States, Israel
- Volunteers
- 40 people
- Sponsor
- Inotek Pharmaceuticals Corporation
Ischemic Heart Disease, ST-segment Elevation Myocardial Infarction
Late Reperfusion With Percutaneous Coronary Intervention in Patients With ST-segment Elevation Myocardial Infarction
Although recommended therapy for patients with ST-segment elevation myocardial infarction is primary PCI, it remains unestablished whether patients with a symptom duration of more 12 hours benefit from acute revascularisation.
- Trial name
- LATE-MI (NCT02445885)
- Testing
- PCI
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Thomas Engstrom
Percutaneous Transluminal Coronary Angioplasty, Coronary Artery Disease
The European Bifurcation Club Left Main Study
The objective of the study is to investigate clinical outcomes following single versus dual stenting strategies for the treatment of true bifurcation distal left main coronary artery lesions.
- Trial name
- EBC MAIN (NCT02497014)
- Testing
- 1 Stent, 2 Stents
- Where
- 24 sites in Denmark, France and 6 more
- Volunteers
- 450 people
- Sponsor
- European Cardiovascular Research Center
Arteriovenous Fistula Renal Dialysis Devices Obstruction
Primary Patency in Post-angioplasty Dysfunctional Arteriovenous Fistula in Renal Dialysis: Paclitaxel-releasing PTA Balloon Catheter vs PTA Balloon
In recent years the use of paclitaxel releasing percutaneous transluminal angioplastic (PTA) balloon catheter is spreading in vascular pathology, mainly in stenosis infrainguinal arteries.
- Trial name
- FISBAL (NCT02565953)
- Testing
- Paclitaxel-releasing PTA balloon catheter, PTA balloon catheter
- Where
- 4 sites in Spain
- Volunteers
- 134 people
- Sponsor
- Fundación Pública Andaluza Progreso y Salud