Clinical trials: Primary Care
Feasibility Randomized Control Trial
Mindfulness-Based Stress Reduction With Older Adults Living With Cognitive Impairment in Primary Care.
People living with subjective cognitive decline (SCD) or mild cognitive impairment (MCI) experience less efficiency in performing complex everyday tasks, which may result in a general sense of discontentment and decreased…
- Trial name
- NCT03867474
- Testing
- Mindfulness-Based Stress Reduction (MBSR)
- Where
- 2 sites in Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Women's College Hospital
Colorectal Cancer (CRC) Screening, CRC Screening
Improving Colorectal Cancer Screening Uptake Through Education and Stool-Based Testing Outreach
This is a mixed-methods implementation pilot combining an educational intervention with a mailed stool-based testing outreach feasibility study within a resident primary care clinic.
- Conditions
- Colorectal Cancer (CRC) Screening, CRC Screening, Rectal Cancer, Colon Cancer
- Trial name
- NCT07781774
- Testing
- Colorectal Cancer Education Materials, Cologuard test kit, Fecal immunochemical test kit
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Non-communicable Diseases (NCD)
Enabling Environments for Non-communicable Disease Risk Reduction in Ethiopia
The ENABLE study focuses on pregnant women attending routine antenatal care (ANC) in urban primary health care facilities in four Ethiopian cities.
- Trial name
- ENABLE (NCT07442318)
- Testing
- Structured lifestyle counseling integrated into ANC, Standard routine ANC
- Where
- 4 sites in Ethiopia
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Cardiovascular Disease, Hypertension
Phase II Study of Heart Polypill Safety and Efficacy in Primary Prevention of Cardiovascular Disease
Cardiovascular is a major cause of mortality in Iran, accounting for 45.7% of deaths. In Golestan (North Eastern Iran) preliminary findings from follow-up of the Golestan Cohort are consistent with national figures: with 45% (at…
- Conditions
- Cardiovascular Disease, Hypertension, Hyperlipidemia, Heart Disease
- Trial name
- Polypill (NCT00603590)
- Testing
- Polypill
- Where
- Iran
- Volunteers
- 475 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Decision Making, Shared
DECIdE, Shared DECIsion in hEalth : the Real-life Impact Study
The aim of the DECIdE study is to evaluate the effect of a decision aid (the DECIdE tool) for shared decision making concerning optional prescription drugs on the level of uncertainty-certainty or comfort-inconfort (= decisional…
- Trial name
- DECIdE (NCT06052917)
- Testing
- DECIdE
- Where
- 4 sites in France
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Evaluation of the Impact of the MSProgress Quality Approach Support Tool on the Evolution of the Indicators Chosen by the MSPs in Comparison With Standard Care
Impact Study of the MSProgress Quality Approach Support Tool for Healthcare Centers Multiprofessionals (MSP) of the AUvergne-Rhône-Alpes Region Using a Mixed Method Evaluating the Evolution of Indicators Chosen by MSPs and Their Use in Multi-professional Teams
Since 2008, the Federation of Health Centers and Coordinated Practice in Auvergne Rhône-Alpes (FemasAURA\&Co) has been supporting healthcare centers Multiprofessionals (MSPs) in their development in the Auvergne-Rhône-Alpes…
- Trial name
- QualiMSP'AURA (NCT07179289)
- Testing
- Provision of the MSProgress quality approach support tool
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Smoking Cessation
Combining Default Choices and a Decision Aid to Improve Tobacco Cessation
The FIRST cluster randomized trial will evaluate the effect of 1) a training program encouraging general practitioners to offer smoking cessation treatment as a default choice to all current smokers consulting a general…
- Trial name
- FIRST (NCT04868474)
- Testing
- Training program and decision aid, Refresher course
- Where
- 2 sites in France, Switzerland
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
White Coat Hypertension
Short Term Reproducibility of Office White-coat Effect
While a theoretical increase in systolic blood pressure (BP) of 10 mmHg can triple the relative risk of cardiovascular disease (CVD), the potential presence of a white coat effect (WCE) can interfere with the assessment of blood…
- Trial name
- REBBRE (NCT06523062)
- Testing
- blood pressure measurement
- Volunteers
- 922 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
High Blood Pressure, Hypercholesterolemia
Cardiovascular Risk Factors And Intensive Dietary Counselling
The Intensive Dietary Counselling (IDC) intervention is a prevention and health promotion activity. It is being implemented by the Andalusian Health Service to reinforce basic intervention advice on healthy diet and exercise.
- Conditions
- High Blood Pressure, Hypercholesterolemia, Tobacco Smoking
- Trial name
- NCT02173600
- Testing
- Group-level Intensive dietary Counselling, Individual-level Intensive Dietary Counselling
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Andalusian Regional Ministry of Health
Physical Activity, Diet
Evaluation of the "Americans in Motion - Healthy Interventions" Project
This research project brings together the American Academy of Family Physicians (AAFP) National Research Network (AAFP-NRN) and the AAFP's public health initiative, Americans In Motion (AIM).
- Conditions
- Physical Activity, Diet, Mental Health
- Trial name
- AIM-HI (NCT00534482)
- Testing
- Enhanced Office, Conventional Office, AIM-HI program with enhanced feedback
- Where
- United States
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- American Academy of Family Physicians
Breast Carcinoma
Mobile Health Patient Navigation for the Improvement of Screening and the Early Detection of Breast Cancer in Women Accessing Primary Care Clinics in Kenya
This clinical trial develops and studies how well mobile health (m-Health) patient navigation (PN) strategies work to improve screening and the early detection of breast cancer in women accessing primary care clinics in Kenya.
- Trial name
- NCT07764796
- Testing
- Best Practice, Discussion, Interview - Stakeholder
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Emory University
HPV-Related Cervical Carcinoma, Physician-Patient Relations
An Observational Study of GP Verbal Reminders Upon Cervical Screening
Cervical cancer screening is offered to all women in the United Kingdom (UK) between the ages of 24.5 and 64 years of age. The majority of screening is performed in primary care and the rate remains stubbornly below 80%, despite…
- Trial name
- VRCS (NCT04970394)
- Testing
- Cervical Screening Reminder
- Where
- United Kingdom
- Volunteers
- 724 people, healthy volunteers welcome
- Sponsor
- Dr. Faizan Awan
Contraception, Contraception Behavior
Patient-Centered Reproductive Decision Support Tool for Women Veterans
The investigators have developed a web-based decision support tool to help women Veterans get the information and care they need to achieve their reproductive goals, whether that includes optimizing their health before desired…
- Conditions
- Contraception, Contraception Behavior, Prepregnancy Health, Reproductive Health
- Trial name
- MyPath (NCT04584294)
- Testing
- MyPath Web-Based Informational and Decision Support Tool
- Where
- 12 sites in United States
- Volunteers
- 465 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Chronic Disease
Outreach Visits to Optimize Chronic Care Management in General Practice: A Cluster Randomized Trial
The aim of this project is to motivate and support general practice clinics in implementing the visions and recommendations presented in two of the disease specific programmes for chronic care management (for chronic obstructive…
- Trial name
- Output (NCT01297075)
- Testing
- Outreach visits
- Where
- 2 sites in Denmark
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Research Unit Of General Practice, Copenhagen
ATC/DDD, Antibiotic Utilization
Using the ATC/DDD to Monitor Antibiotic Use at Lower Primary Care Facilities in Southwestern Uganda
This is a non blinded two arm cluster randomized control trial, aimed at assessing the feasibility of using the Anatomical Therapeutic Chemical Classification/define Daily Doses system tool to monitor antibiotic use at lower…
- Trial name
- NCT04782011
- Testing
- ATC/DDD
- Where
- Uganda
- Volunteers
- 1,406 people, healthy volunteers welcome
- Sponsor
- Makerere University
Health Knowledge, Attitudes, Practices
The Science Tooth Fairy: A Randomized Trial of a Storytelling-Based Educational Intervention to Promote Primary Tooth Donation in a Pediatric Setting
Study Overview Primary ("baby") teeth are unique biological samples because they can permanently store information about a child's early life health and development.
- Trial name
- STF RCT (NCT07711301)
- Testing
- Science Tooth Fairy Narrative, Cavities vs. Toothpaste, book by Didi Dragon
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Pulmonary Function
Diet Intervention Spirometry and Tobacco
Epidemiologic studies suggest that some nutrients can be affected lung function. Moreover, no previous studies have prospectively evaluated the effect of the Mediterranean dietary pattern in lung function in smokers.
- Trial name
- DIET (NCT02151669)
- Testing
- Mediterranean Diet
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Chronic Obstructive Pulmonary Disease (COPD)
Translating The GOLD COPD Guidelines Into Primary Care Practice
This project will evaluate the translation of the Gold (the Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease) COPD guidelines into primary care practice.
- Trial name
- LungAge (NCT01237561)
- Testing
- provider support tools plus spirometer
- Where
- United States
- Volunteers
- 3,593 people, healthy volunteers welcome
- Sponsor
- Memorial Hospital of Rhode Island
Frailty, Sarcopenia
A Randomized Control Trial of an Intervention to Reverse Frailty and Enhance Resilience Through Exercise and Education
Resistance training done at home and protein supplementation may be the most effective and easiest to implement interventions to reverse frailty and build resilience.
- Trial name
- REFEREE (NCT04628754)
- Testing
- Exercise and protein
- Where
- Ireland
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University College Dublin
PTSD
Primary Care-Based Mindfulness Intervention for Veterans With PTSD
Primary care patients typically do not receive adequate PTSD treatment because of their reluctance to engage in empirically-supported treatments offered in specialty care settings.
- Trial name
- NCT02399696
- Testing
- Primary Care-Brief Mindfulness Program, Primary Care-Treatment as Usual
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Syracuse VA Medical Center
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