Clinical trials: Primary Care Genetics
Cardiovascular Diseases (CVD)
Healthy Living With Online suPport & Education for Cardiovascular Disease in the Primary Care Setting
This pragmatic four-arm (1:1:1:1) parallel cluster randomised controlled trial (cRCT) aims to evaluate the effectiveness of reducing the risk of cardiovascular disease (CVD) through three combinations of interventions for…
- Trial name
- HOPE-CVD-GP (NCT06099353)
- Testing
- Heart Age, Heart Age-HOPE-CVD App, Communication of Genetic Risk Score
- Where
- Singapore
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Primary Ciliary Dyskinesia
Utility of PCD Diagnostics to Improve Clinical Care
This cross-sectional and longitudinal observational study is to gather data on the utility of tests that are used to make a diagnosis of primary ciliary dyskinesia (PCD).
- Trial name
- PCD (NCT05889013)
- Testing
- Nasal Nitric Oxide testing
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Connecticut Children's Medical Center
Asthma, Allergic Rhinitis
Evaluation of an Integrated Care Project
The purpose of the study is to investigate the effectiveness and cost-effectiveness of the integrated care program of a statutory health insurance offering additional homeopathic treatment to their members
- Conditions
- Asthma, Allergic Rhinitis, Atopic Eczema, Migraine
- Trial name
- ediva (NCT01854580)
- Where
- Germany
- Volunteers
- 3,960 people
- Sponsor
- Charite University, Berlin, Germany
Physician's Role, Smoking Cessation
Personalized Tobacco Treatment in Primary Care (MOTIVATE)
This study examines the application of precision treatment intervention for smoking cessation from both the clinician perspective and patient perspective, and compares it to usual care on tobacco treatment in the primary care…
- Conditions
- Physician's Role, Smoking Cessation, Smoking
- Trial name
- NCT05846841
- Testing
- Precision Treatment, Usual Care
- Where
- United States
- Volunteers
- 850 people
- Sponsor
- Washington University School of Medicine
Neurofibromatosis 1
Tailoring an Online Platform to Promote Evidence-Based Care for Adults With Neurofibromatosis 1 and Low Health Literacy
This decentralized, randomized study seeks to assess the feasibility, acceptability, and preliminary effectiveness of two approaches to assisting Neurofibromatosis 1 (NF1) patients with low health literacy improve their…
- Trial name
- NCT07233408
- Testing
- NF1 Educational Videos, Peer Navigator, Letters about NF1 Care
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Primary Ciliary Dyskinesia
Use of Nasal Nitric Oxide Testing in Improving Primary Ciliary Dyskinesia Clinical Care
this study is aiming at learning more about primary ciliary dyskinesia (PCD) and tests that are used to diagnose this condition.
- Trial name
- NCT05287022
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Arkansas Children's Hospital Research Institute
HIV Infections, Men
Improving HIV Testing, Linkage, and Retention in Care for Men Through U=U Messaging
This study will evaluate the impact of U=U messaging and counseling on gaps in the HIV care cascade for men, including testing uptake and ART initiation (Aim 1), achieving viral suppression and retention in care (Aim 2) in two…
- Conditions
- HIV Infections, Men, Treatment Adherence
- Trial name
- NCT05602376
- Testing
- U=U testing messaging scripts, U=U adherence messaging scripts
- Where
- 2 sites in South Africa
- Volunteers
- 3,642 people, healthy volunteers welcome
- Sponsor
- Desmond Tutu HIV Foundation
Familial Hypercholesterolemia
Improving Identification of Familial Hypercholesterolaemia in Primary Care (FAMCAT)
Multi-centre, non-randomised, non-controlled quasi-experimental study with nested qualitative study and economic appraisal. Improving the identification of patients at high risk of cardiovascular disease in primary care, caused…
- Trial name
- FAMCAT (NCT03934320)
- Testing
- FAMCAT
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Pharmacogenetic Testing
Pharmacogenetic Testing in Primary Care
The purpose of this study is to further integrate pharmacogenetic (PGx) testing into clinical practice by educating physicians about pharmacogenetics and offering testing to their patients.
- Trial name
- NCT01600846
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Duke University
Alzheimer Disease, Cognitive Dysfunction, Cognitive Disorder
DIV-AD BARCELONA: Alzheimer's Blood-Based Biomakers for a Diverse Community
The DIV-AD study aims to find out whether levels of Alzheimer's disease markers in blood differ among the main ethnical groups living in central Barcelona.
- Conditions
- Alzheimer Disease, Cognitive Dysfunction, Cognitive Disorder, Dementia, Neurodegenerative Disease
- Trial name
- DIV-AD (NCT07521722)
- Where
- Spain
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Primary Antibody Deficiencies
Early Detection of Primary Antibody Deficiencies in Primary Care Facilities by an Algorithm Driven Selection of Serologic Testing in Individuals at Risk.
Rationale: Primary antibody deficiencies (PAD) encompass a group of rare heterogeneous diseases. The clinical presentation may vary widely, including infectious and autoimmune symptoms and increased risk of malignancy.
- Trial name
- GP-PAD II (NCT05310604)
- Testing
- Blood withdrawal
- Where
- Netherlands
- Volunteers
- 104 people
- Sponsor
- UMC Utrecht
Sickle Cell Disease
Disseminating NIH Evidence Based Sickle Cell Recommendations in North Carolina
This project will improve the efficiency and quality of healthcare for persons with sickle cell disease, an under-served and at risk population by implementing a co-management model of care.
- Trial name
- NCT03253211
- Where
- United States
- Volunteers
- 4,392 people
- Sponsor
- Duke University