Clinical trials: Primary Closure
Primary Open-angle Glaucoma, Primary Angle-Closure Glaucoma
Prevalence of Ocular Surface Disease in Malaysian Glaucoma Patients
This is a prospective, multi-centre, cross sectional observational study to determine the prevalence of ocular surface disease (OSD) in glaucoma patients, nationwide.
- Conditions
- Primary Open-angle Glaucoma, Primary Angle-Closure Glaucoma, Pseudoexfoliation Glaucoma, Pigment Dispersion Glaucoma
- Trial name
- NCT04609345
- Volunteers
- 400 people
- Sponsor
- Santen Pharma Malaysia Sdn Bhd
Obstructive Sleep Apnea
REV 002 Observational Study of the ReVENT Sleep Apnea System: Minimally Invasive Treatment for Obstructive Sleep Apnea
The purpose of this post-market observational study is to assess the effectiveness and patient perception of benefit of the ReVENT Sleep Apnea System in patients diagnosed with Obstructive Sleep Apnea due to primary tongue base…
- Trial name
- NCT02180815
- Testing
- ReVENT Sleep Apnea System
- Where
- 14 sites in Belgium, Czechia and 3 more
- Volunteers
- 50 people
- Sponsor
- Revent Medical International B.V.
Migraine Disorders, Heart Septal Defects, Atrial
ESCAPE Migraine Trial
The purpose of this two arm controlled double-blind study is to determine the safety and effectiveness of PFO closure (closing a hole in the wall of the heart) in reducing the frequency of migraine headaches, in patients who…
- Trial name
- NCT00267371
- Testing
- PFO Closure with Premere investigational device., Medical management/current medications per standard of care by personal physician.
- Where
- 37 sites in United States
- Volunteers
- 168 people
- Sponsor
- Abbott Medical Devices
Dehiscence of Laparotomy Wound, Surgical Wound Infection
Short Stitch Monomax®
A number of studies identifies abdominal hernia as the most frequent postoperative complication following laparotomy with percentages of 9-20% - depending on duration of follow-up.
- Trial name
- Short-Stitch (NCT01938222)
- Testing
- Short Stitch
- Where
- Germany
- Volunteers
- 351 people
- Sponsor
- Diakonie-Klinikum Schwäbisch Hall gGmbH
Glaucoma Eye, Angle Closure Glaucoma
Testing YAG Laser Iridotomy for Primary Angle-Closure Glaucoma
This study evaluates the effectiveness and safety of YAG laser peripheral iridotomy performed at two different locations (temporal and inferior) in patients with primary angle-closure glaucoma, a leading cause of blindness…
- Trial name
- yag laser PI (NCT07195370)
- Testing
- peripheral iridotomy
- Where
- Iran
- Volunteers
- 150 people
- Sponsor
- Isfahan University of Medical Sciences
Diverticular Disease of Colon, Colostomy Complication
Comparing Hartmann's Procedure and Primary Resection With Anastomosis in Hinchey III-IV Diverticulitis: Focus on Ostomy Closure and Long-Term Outcomes
Brief Summary This multicenter study compares the effectiveness of primary anastomosis with diverting loop ileostomy to Hartmann's procedure for managing perforated sigmoid diverticulitis in stable patients.
- Conditions
- Diverticular Disease of Colon, Colostomy Complication, Colostomy - Stoma
- Trial name
- ARES (NCT06794905)
- Volunteers
- 578 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Primary Angle Closure Glaucoma
The Effect of Phacoemulsification on Intraocular Pressure in Primary Angle Closure Glaucoma (PACG) Patients At Phanat Nikhom Hospital, Chonburi Province
BACKGROUND: Primary angle closure glaucoma (PACG) is one of a leading cause of blindness worldwide including Thailand. This problem impact to the overall health of people and health care system.
- Trial name
- NCT06252246
- Testing
- Phacoemulsification machine
- Where
- Thailand
- Volunteers
- 121 people
- Sponsor
- Phanatnikhom Hospital
Breast Neoplasms
New Formula to Predict the Need for Reconstructive Coverage Following Mastectomy
Mastectomy is a cornerstone operative procedure in breast cancer treatment leaving a raw area behind with possibility of failure of primary closure sometimes with unavailability of facilities of reconstruction.
- Trial name
- NCT04677075
- Testing
- mastectomy
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Zagazig University
Pneumonia, Pneumococcal, Diabetes Mellitus
Text Message-Based Nudges Prior to Primary Care Visits to Increase Care Gap Closure
Primary care visits are a key aspect of clinical care focused on helping patients to close care gaps related to preventive care such as vaccination, diabetes testing, statin therapy and cancer screening.
- Conditions
- Pneumonia, Pneumococcal, Diabetes Mellitus, Breast Cancer, Colorectal Cancer
- Trial name
- NCT05799976
- Testing
- Text message nudge
- Where
- United States
- Volunteers
- 29,334 people, healthy volunteers welcome
- Sponsor
- Mitesh Patel
Pain
Pain Study of Rectus Muscle Closure at Cesarean Delivery
Suture reapproximation of the rectus muscles at primary cesarean delivery is a common practice about which there are no data. Some Obstetricians believe that suture reapproximation of the rectus muscles increases post-operative…
- Trial name
- NCT00505362
- Testing
- Rectus closure
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Stanford University
Primary Angle-Closure Glaucoma
Liwan Eye Study: the Fourth Follow-up
Primary angle-closure glaucoma (PACG) is one of the major causes of blindness affecting more than 20 million patients worldwide.
- Trial name
- NCT06333470
- Testing
- Primary angle closure diseases
- Volunteers
- 600 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Surgical Site Infection
Efficacy Study of Delayed Primary Closure to Reduce Rate of Wound Infection in Complicated Appendicitis
Research hypothesis: Does delayed primary wound closure after appendectomy in adults with complicated appendicitis reduce postoperative superficial surgical site infection compare to primary wound closure.
- Trial name
- NCT01659983
- Testing
- Primary wound closure
- Where
- 7 sites in Thailand
- Volunteers
- 600 people
- Sponsor
- Ramathibodi Hospital
Glaucoma, Angle-Closure
Implantation of Capsular Tension Ring in Primary Angle Closure Patients With Zonular Laxity or Dialysis
Primary angle closure glaucoma (PACG) is the main type of glaucoma in China, which includes acute and chronic PACG. According to the International Society of Geographical and Epidemiological Ophthalmology (ISGEO), this spectrum…
- Trial name
- NCT05542290
- Testing
- Capsular tension ring implantation, No capsular tension ring implantation
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Beijing Tongren Hospital
Glaucoma, Angle-Closure, Cataract
Comparison of Phacotrabeculectomy and Trabeculectomy in the Treatment of Primary Angle-closure Glaucoma (PACG)
Primary angle closure glaucoma (PACG) is caused by contact between the iris and trabecular meshwork, which in turn obstructs outflow of the aqueous humor from the eye.
- Trial name
- NCT01298635
- Testing
- combined phacotrabeculectomy, trabeculectomy
- Volunteers
- 31 people
- Sponsor
- Sun Yat-sen University
Flap Advancement, Primary Wound Closure
Flap Advancement Techniques in Ridge Augmentation
Different augmentation techniques has been proposed to resolve problem of hard and/or soft tissue ridge defects to enable dental implant placement.
- Trial name
- NCT03071523
- Testing
- coronally advanced lingual flap, periosteal releasing incision
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Cairo University
Injury Caused by Animal Bites, Wound Infection
Incisional Negative Pressure Therapy to Prevent Animal Induced Wound Infection
Animal injuries are a significant public health issue, with the most common being bites or scratches from cats and dogs. Every year, over 40 million people in China are bitten or scratched by cats and dogs, which can lead to…
- Trial name
- NCT06558942
- Testing
- incisional negative pressure wound technology
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University First Hospital
Hernia Abdominal Wall, Botox Injection
Preoperative BOTOX® Injection for Large Ventral Hernia Repair
This study is for adults who need open surgery to repair a very large abdominal (ventral) hernia. This study tests whether a one-time, image-guided injection of a medicine commonly known as "BOTOX®" (onabotulinumtoxinA) into the…
- Conditions
- Hernia Abdominal Wall, Botox Injection, Hernia Incisional Ventral, Hernia Repair With Compartment Syndrome
- Trial name
- PRETOX (NCT07220382)
- Testing
- OnabotulinumtoxinA Injection, OnabotulinumtoxinA, 0.9 % Normal Saline
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- The Cleveland Clinic
Glaucoma
Intraocular Pressure (IOP) Lowering Effect of Selective Laser Trabeculoplasty Versus Prostaglandin Analogues in Angle Closure Glaucoma
Glaucoma affects 66 million people worldwide and is the leading cause of irreversible blindness, and Primary angle-closure glaucoma (PACG) is a major form of glaucoma in Asia.
- Trial name
- NCT01004900
- Testing
- Selective Laser Trabeculoplasty, Travoprost/ Timolol/ Azopt/ Brimonidine
- Where
- Singapore
- Volunteers
- 90 people
- Sponsor
- Singapore Eye Research Institute
Patent Foramen Ovale
PFx Closure System in Subjects With Cryptogenic Stroke,Transient Ischemic Attack,Migraine or Decompression Illness(PFO)
The primary objective of this study is to demonstrate the safety and performance of the PFx Closure System when utilized for patients with PFOs suffering from cryptogenic stroke, transient ischemic attack, migraine or…
- Trial name
- NCT00335296
- Testing
- PFx catheter
- Where
- 4 sites in Belgium, France and 1 more
- Volunteers
- 100 people
- Sponsor
- Cierra
Internal Hernias
Internal Hernias After Gastric Bypass Can be Prevented Safely With Primary Closure of All Mesenteric Defects With Clips
The purpose of this study is to determine whether closure of all mesenteric defects with clips at the time of Gastric bypass, can avoid the complication of late bowel obstruction- internal hernias
- Trial name
- NCT01595230
- Testing
- Closing the mesenteric defects with clips during opration
- Where
- 2 sites in Denmark
- Volunteers
- 405 people
- Sponsor
- Region Zealand