Clinical trials: Primary Headache Disorders
Migraine
Comparing Efficacy and Safety of 2 Dose Regimens of Subcutaneous Administration of TEV-48125 Versus Placebo for the Preventive Treatment of Chronic Migraine
The study is being conducted to evaluate two doses of TEV-48125 in adult patients with chronic migraine
- Trial name
- NCT02621931
- Testing
- Fremanezumab
- Where
- 273 sites in United States, Canada and 7 more
- Volunteers
- 1,130 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Migraine Headaches
Acute Migraine Treatment in the ED With Gepants
This study evaluates the effectiveness of rimegepant 75 mg orally disintegrating tablet (ODT) single-dose or zavegepant 10 mg nasal spray single-dose as acute migraine treatments during Emergency Department (ED) encounters.
- Trial name
- NCT06985342
- Testing
- Rimegepant, Zavegepant
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Headache
Management of Headache Disorders: A Clinical Trial Screening for Prognostic Patient Characteristics
The management of headache disorders is too often based upon trial and error or on personal beliefs and opinions. Seldom it is based on scientific arguments.
- Trial name
- NCT00298142
- Testing
- Usual Care provided by a medical doctor (GP or Neurologist), Usual care plus Physio-/ Manual Therapy
- Where
- 14 sites in Belgium
- Volunteers
- 120 people
- Sponsor
- Vrije Universiteit Brussel
Migraine in Children
A Survey Study to Assess the Accessibility of the Nerivio Device At School
This is a retrospective survey-study to assess the accessibility, preference, and frequency of adolescents using Nerivio by itself, in combination with pharmacological medications, or not at all, in the school setting.
- Trial name
- NCT06180577
- Testing
- Nerivio
- Where
- United States
- Volunteers
- 332 people
- Sponsor
- Theranica
Migraine
Transcriptomic and Biochemical Changes During a Migraine Attack
Despite the fact that migraine is a common disorder, the pathogenesis is still not fully elucidated. Studying transcriptomic and biochemical changes during induced and spontaneous migraine-attacks will enhance our understanding…
- Trial name
- NCT02468622
- Testing
- Blood samples
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Danish Headache Center
Chronic Cluster Headache
Prevention and Acute Treatment of Chronic Cluster Headache Compared to Standard of Care
Subjects enrolled into this 10 week study will for the first two weeks document the number of cluster headaches and the means of treating (medication) of these attacks. Subjects will then be randomized to into either two groups.
- Trial name
- NCT01701245
- Testing
- GammaCore
- Where
- 10 sites in Belgium, Germany and 2 more
- Volunteers
- 97 people
- Sponsor
- ElectroCore INC
Migraine
Educational Intervention in Patients With Migraine
Introduction: Despite the numerous pharmacological treatment options available for migraine attacks and for the prevention of thereof, less than 30% of patients with migraine are highly satisfied with their current treatment.
- Trial name
- M01 (NCT03381924)
- Testing
- Educational programme, Routine clinical practice
- Where
- Spain
- Volunteers
- 116 people
- Sponsor
- Basque Health Service
Episodic Migraine
12-Week Placebo-controlled Study of Atogepant for the Preventive Treatment of Migraine in Participants With Episodic Migraine
To evaluate the safety and tolerability of atogepant 30 mg and 60 mg once a day for the prevention of migraine in participants with episodic migraine.
- Trial name
- NCT03777059
- Testing
- Atogepant
- Where
- 138 sites in United States
- Volunteers
- 910 people
- Sponsor
- Allergan
Acute Migraine Headache
Oral Medications for the Management of Acute Migraine Headache in the Emergency Department
The goal of this pilot randomized control trial is to assess the feasibility of our patient recruitment and data collection strategy ahead of a full scale RCT investigating the efficacy of oral v.
- Trial name
- NCT05983354
- Testing
- Oral metoclopramide and ibuprofen, Intravenous metoclopramide and ketorolac
- Sponsor
- Health Sciences North Research Institute
Migraine
A Study to Test the Safety and Effectiveness of MK-0974 (Telcagepant) Co-administered With Ibuprofen or Acetaminophen in Patients With Migraines With or Without Aura (MK-0974-046)
This study will test the safety and how effective telcagepant is when taken with ibuprofen or acetaminophen in participants with migraine with or without aura.
- Trial name
- NCT00758836
- Testing
- ibuprofen, acetominophen, telcagepant
- Volunteers
- 683 people
- Sponsor
- Merck Sharp & Dohme LLC
Migraine
Influence of a Dietary Supplement as Treatment of Migraine in Children and Adolescents
Migraine in children and adolescents can be associated with low serum levels of coenzyme q10, the key-enzyme of mitochondrial energy production.During migraine attacks inflammation is an important issue.
- Trial name
- NCT01010711
- Testing
- Migra 3
- Where
- 2 sites in Germany
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Complen Health GmbH
Migraine
Migraine Among Sohag University Students
Diagnosis of migraine among students and detect frequency among them and detect how far migraine affect their life
- Trial name
- NCT06536920
- Testing
- Migraine screening questionnaire
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sohag University
Migraine
Metformin for the Prevention of Episodic Migraine (MPEM)
The investigators will evaluate the safety and efficacy of metformin for preventive treatment of migraine in a randomized, double-blind, placebo-controlled, crossover trial.
- Trial name
- MPEM (NCT02593097)
- Testing
- Metformin
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Mayo Clinic
Headache, Headache Disorders
Responding With Evidence and Access for Childhood Headaches
This comparative effectiveness study will clarify current first-line preventive treatment approaches for use by neurologists, psychologists, and primary care providers in the context of real world care, and will demonstrate the…
- Conditions
- Headache, Headache Disorders, Headache, Migraine, Migraine
- Trial name
- NCT05889624
- Testing
- CBT, Amitriptyline
- Where
- 15 sites in United States
- Volunteers
- 400 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Migraine Without Aura, Headache
Effect of Sumatriptan on Levcromakalim-Induced Symptoms in Individuals With Migraine
The study aims to explore the effects of Sumatriptan on Levcromakalim-induced migraine in individuals with migraine without aura.
- Trial name
- SLIM (NCT05211050)
- Testing
- Levcromakalim, Sumatriptan, Saline
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Danish Headache Center
Migraine
Safety, Efficacy and Pharmacokinetics of ALD403
The purpose of this study is to assess the safety, pharmacokinetics and efficacy of a single dose of ALD403 in the prevention of migraine headache in frequent episodic migraineurs for 24 weeks.
- Trial name
- NCT01772524
- Testing
- ALD403
- Where
- 26 sites in United States
- Volunteers
- 163 people
- Sponsor
- Alder Biopharmaceuticals, Inc.
Migraine Without Aura
Study the Effect of Acupuncture on Migraine Patient Without Aura Via Functional Magnetic Resonance Imaging.
This study recruits 30 subjects into three groups, including two experimental groups and one control group. The two experimental groups receive acupuncture treatment for 4 weeks and two times functional magnetic resonance imaging…
- Trial name
- NCT04636359
- Testing
- Acupuncture stimulation
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beijing University of Chinese Medicine
Migraine
PSG and Neuroendocrine Hormones in Subjective Cognitive Impaired Patients With Transformed Migraine
Transformed migraine is the most common and challenging subtype of chronic daily headache disorders35. Patients with transformed migraine often report an evolutionary process that occurs over months or years in which headaches…
- Trial name
- NCT04413110
- Testing
- Polysomnography
- Where
- Egypt
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Mansoura University Hospital
Migraine
Migraine Survey in Gulf Region
The objective of this study was to evaluate the effect of erenumab on medication-specific treatment satisfaction in patients who newly started on erenumab over 12 weeks
- Trial name
- NCT06237062
- Testing
- erenumab
- Volunteers
- 37 people
- Sponsor
- Novartis Pharmaceuticals
Migraine Headache
Drug and Non-Drug Treatment Of Severe Migraine
The purpose of this study is to determine if the addition of preventive medication, behavior migraine management or the combination of preventive medication and behavior migraine management improves the outcome of optimal acute…
- Trial name
- TSM (NCT00910689)
- Testing
- Propranolol or nadolol, Behavioral Migraine Management (BMM), Optimal Acute Therapy
- Where
- 2 sites in United States
- Volunteers
- 232 people
- Sponsor
- Ohio University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.