Clinical trials: Primary Headache Disorders
Headache, Analgesia
The Use of Virtual Reality Applications in Tension-Type Headaches
The primary aim of this research is to objectively assess the impact of virtual reality (VR) technology on pain symptoms in tension-type headache patients.
- Conditions
- Headache, Analgesia, Tension-Type Headache
- Trial name
- NCT06155669
- Testing
- Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ankara City Hospital Bilkent
Migraine
The Headache Inducing Effects of Cilostazol on Migraine Patients
We will use Cilostazol as a tool to investigate its headache inducing effects in migraine patients.
- Trial name
- NCT01841827
- Testing
- Cilostazol
- Where
- Denmark
- Volunteers
- 14 people
- Sponsor
- Danish Headache Center
Migraine, Chronic Headache
Does Topiramate Adjust the Excitability of the Brain in Migraine Sufferers?
The purpose of the study is to determine by the use of non-invasive magnetic stimulation if the medication Topiramate adjusts the excitability of the migraine sufferer's brain.
- Trial name
- NCT00286923
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Emerald City Headache Organization
Migraine
Migraine Treatment Satisfaction With Treximet Versus Concomitant 2 Aleve and Imitrex
This is an open label, 6 month cross over study in 50 migraine patients fulfilling International Headache Society Classification criteria for migraine headache with and without aura having 2-6 migraines per month and not over 14…
- Trial name
- NCT01450995
- Testing
- Treximet, Imitrex and two Aleve
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stephen H. Landy, M.D.
Chronic Migraine
Treximet in the Treatment of Chronic Migraine
This study is being conducted to evaluate the hypothesis that use of Treximet in patients with chronic migraine, when used on a short term daily basis and as rescue for break through attacks, will reduce migraine frequency and…
- Trial name
- NCT01090050
- Testing
- Sumatriptan/Naproxen Sodium, Naproxen Sodium
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- Cady, Roger, M.D.
Tension-Type Headache
Evidence-Based Osteopathy for Tension-Type Headache (EBOTTH)
Tension-type headache (TTH) is a very common primary headache disorder, with important costs for both patients and society. Often these patients are not willing to take prophylactic medications and resort to complementary…
- Trial name
- EBOTTH (NCT02592850)
- Testing
- osteopathic manipulative treatment
- Sponsor
- University of Milano Bicocca
Migraine
Study to Evaluate the Efficacy and Safety of Erenumab (AMG 334) in Migraine Prevention
The primary objective of the study was to evaluate the effect of erenumab compared to placebo on the change from baseline in monthly migraine days.
- Trial name
- STRIVE (NCT02456740)
- Testing
- Erenumab
- Where
- 129 sites in United States, Austria and 11 more
- Volunteers
- 955 people
- Sponsor
- Amgen
Migraine Disorders, Headache
The Effect of Intravenous Fluid Therapy in Acute Migraine Attacks
The study is a single-center, double-blind, randomized protocol comparison. The study will be conducted in Marmara University School of Medicine Pendik Training and Research Hospital, Department of Emergency Medicine between…
- Conditions
- Migraine Disorders, Headache, Acute Pain
- Trial name
- NCT04287140
- Testing
- Bolus fluid administration
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Myofascial Pain, Tension-type Headache
Blood Flow Within Active Myofascial Trigger Points Following Massage
The physiological response at the myofascial trigger point (MTrP) to massage is not known, yet would provide important objective evidence for a treatment effect and clarify the resolution process of a MTrP.
- Trial name
- NCT02389140
- Testing
- Trigger point release, Ultrasound
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Colorado, Denver
Migraine Disorders
Valproate Versus Propranolol in Migraine
Investigators aim to compare the effect of valproate versus propranolol in migraine by assessing the absolute reduction in MMD in each group and the percentage of patients who achieved ≥ 50% reduction in the monthly headache days…
- Trial name
- NCT06485726
- Testing
- Valproic Acid 500 MG, Propranolol
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Kafrelsheikh University
Depression, Headaches Chronic
CBT Depression Intervention for Co-Occurring Chronic Headache
Having co-occurring depression and chronic headaches is challenging and can greatly impact one's professional, personal, family, and social life.
- Conditions
- Depression, Headaches Chronic, Migraine Disorders
- Trial name
- NCT02870725
- Testing
- CBT Individual Psychotherapy
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- University of Georgia
Migraine Disease, Patent Foramen Ovale
Migraine Headaches Elimination With Patent Foramen Ovale-Directed Therapy
Migraine is a common and often disabling condition, but its exact causes are not fully understood. Some people with migraines have a small opening in the heart wall called a patent foramen ovale (PFO).
- Trial name
- COMFORT-PFO (NCT07629635)
- Testing
- Prasugrel 5mg, Transcatheter Closure of Patent Foramen Ovale
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Columbia University
Migraine Disorders
American Migraine Prevention Study
The purpose of this study is to evaluate the use of nutritional supplementation and dietary management for the reduction in frequency, duration, and intensity of migraine headache pain.
- Trial name
- NCT00363506
- Testing
- Serotona Plus and dietary behavior management
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Dynamic Health Resources
Tension-Type Headache
Muscle Strength in Shoulder and Neck Muscles in Tension Type Headache Patients. Effect of Specific Strength Training
Background: Tension Type Headache (TTH) is highly frequent and is of great socio-economic importance. Andersen et al. 2008 has shown that maximal muscle strength is reduced in women with trapezius myalgia.
- Trial name
- NCT02984826
- Testing
- Strength training, Ergonomic and posture
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Migraine
Effect of Osteopathic Intervention on Migraine
Migraine is a common, disabling neurological condition characterized by severe, often unilateral pain accompanied by sensory symptoms like nausea and photophobia.
- Trial name
- NCT07542340
- Testing
- Osteopathic Intervention Protocol
- Volunteers
- 45 people
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Migraine
Efficacy & Safety Of Zomig Nasal Spray For Acute Migraine Treatment In Subjects 6 To 11 Years, With OLE
To evaluate the efficacy and safety of zolmitriptan nasal spray (ZNS) in the acute treatment of migraine headache in subjects ages 6 to 11 years. Part 1: Approximately 20 weeks (includes screening and double-blind treatment).
- Trial name
- NCT03275922
- Testing
- ZNS
- Where
- 47 sites in United States
- Volunteers
- 374 people
- Sponsor
- Impax Laboratories, LLC
Chronic Migraine, Cluster Headache
Intra-arterial Sphenopalatine Ganglion Block for Patients With Refractory Headache
The purpose of this study is to evaluate the safety and efficacy of intra-arterial (IA) delivery of Dexamethasone and Ketorolac into the arteries supplying the sphenopalatine ganglion (SPG) - a collection of neurons that plays an…
- Conditions
- Chronic Migraine, Cluster Headache, Trigeminal Neuralgia
- Trial name
- NCT04353505
- Testing
- Ketorolac, Dexamethasone
- Where
- United States
- Sponsor
- Weill Medical College of Cornell University
Migraine in Children, Migraine
A Study in Children and Young People With Migraine to Learn What the Body Does to Eptinezumab
The purpose of the study is to investigate how the body absorbs, distributes, and get rid of eptinezumab when given directly into a vein.
- Trial name
- NCT04537429
- Testing
- Eptinezumab
- Where
- 9 sites in United States
- Volunteers
- 28 people
- Sponsor
- H. Lundbeck A/S
Migraine
An Observational Study to Assess Change in Disease Activity When Ubrogepant Tablets Are Combined With Atogepant Tablets to Treat Migraine in Adult Participants
Migraine is a neurological disease characterized by moderate or severe headache, associated with nausea, vomiting, and/or sensitivity to light and sound.
- Trial name
- COURAGE II (NCT05653986)
- Where
- United States
- Volunteers
- 391 people
- Sponsor
- AbbVie
Migraine
ADX10059 Migraine Prevention Study
Evaluation of ADX10059 to prevent migraine attacks
- Trial name
- NCT00820105
- Testing
- ADX10059
- Where
- 31 sites in Austria, Belgium and 3 more
- Volunteers
- 350 people
- Sponsor
- Addex Pharma S.A.
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