Clinical trials: Primary Infertility, active
Pain
Effect of Music in Reducing Pain and Anxiety During Hysterosalpingography in Women With Primary Infertility
This study aims to demonstrate the value of music in lowering pain and anxiety during hysterosalpingography in women with primary infertility
- Trial name
- NCT06772636
- Testing
- music group, non music group
- Volunteers
- 110 people
- Sponsor
- Cairo University
Infertility, Female
Lidocaine Prilocaine Spray in Reducing Pain During Hysterosalpingography in Women With Primary Infertility
We aim to assess the Safety and Efficacy of Cervical Lidocaine Prilocaine Spray in Reducing Pain During Hysterosalpingography in women with primary infertility
- Trial name
- NCT06769204
- Testing
- EMLA SPRAY
- Volunteers
- 90 people
- Sponsor
- Cairo University
Infertility, Female, Premature Ovarian Failure
Is There A Role For Mechanical Stimulation In Ovarian Follicular Activation?
Premature ovarian failure (POI) is a loss of normal function before age 40, leading to infertility and hypoestrogenism. About 1% of women younger than 40 years old and 0.1% before 30 are affected.
- Conditions
- Infertility, Female, Premature Ovarian Failure, IVF
- Trial name
- NCT04390308
- Testing
- Ovarian puncture, Hormonal blood Test, Transvaginal ultrasound
- Where
- United Arab Emirates
- Volunteers
- 70 people
- Sponsor
- ART Fertility Clinics LLC
Anti-Müllerian Hormone, Polycystic Ovarian Syndrome
Clinical Application of Serum Anti-Müllerian Hormone (AMH) Measurements
This study aims to assess the association of Anti-Müllerian hormone (AMH) with polycystic ovarian syndrome, premature ovarian insufficiency and fertility. The main objectives include the following: 1.
- Conditions
- Anti-Müllerian Hormone, Polycystic Ovarian Syndrome, Premature Ovarian Insufficiency, Fertility Issues
- Trial name
- NCT05858307
- Where
- Hong Kong
- Volunteers
- 300 people
- Sponsor
- Chinese University of Hong Kong
Being Diagnosed With Primary Infertility, Having Had an Embryo Transfer for the First Time
Effects of Virtual Reality Glasses and Meditation Music on Anxiety, Pain, Vital Signs, Satisfaction and Pregnancy Outcomes in Embryo Transfer Procedure
The aim of this study is to determine the effects of virtual reality glasses (VRG) and meditation music on anxiety, pain, vital signs, satisfaction and pregnancy outcomes during the embryo transfer (ET) procedure.
- Trial name
- NCT06802692
- Testing
- VR glasses and meditation music group, Meditation music group
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Nuh Naci Yazgan University
Infertility, IVF
Will Autologous Platelet Rich Plasma Able To Restore Ovarian Function?
A-PRP (Autologous Platelet Rich Plasma) is becoming widely used in a variety of medical procedures seeking tissue remodeling and/or healing as an intervention.
- Conditions
- Infertility, IVF, Premature Ovarian Failure, Anti-Mullerian Hormone Deficiency
- Trial name
- NCT04381299
- Testing
- autologous platelet rich plasma, saline solution
- Where
- United Arab Emirates
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Gonadal Dysfunction, Gonadal Failure
Fertility Enhancement Through Regenerative Treatment in Ovaries and Testes
This study investigates the safety and efficacy of stem cell or stem cell-derived exosome therapy for gonadal failure, including testicular failure, hypogonadism, ovarian insufficiency, and premature ovarian failure (POF).
- Conditions
- Gonadal Dysfunction, Gonadal Failure, Azoospermia, Testosterone Deficiency
- Trial name
- FERTILE (NCT06841328)
- Testing
- Stem cells
- Where
- United Arab Emirates
- Volunteers
- 60 people
- Sponsor
- Jumeirah American Clinic
Infertility, Health Education
Health Education for Women With Suspeced Infertility Waiting for Specialized Care
Introduction: Infertility is defined as a couple's inability to achieve pregnancy after 12 months or more of regular unprotected intercourse. In Brazil, it affects around eight million people.
- Conditions
- Infertility, Health Education, Telemedicine, Telehealth
- Trial name
- NCT06979063
- Testing
- Remote Infertility Education and Counseling, Standard Care Arm
- Where
- Brazil
- Volunteers
- 206 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Infertility Primary
The Aim of This Study is to Determine if Oocyte Sorting for Group Culture Using an Artificial Intelligence Image Analysis Tool (MagentaTM) Increases the Usable Blastocyst Yield and Subsequent Pregnancy in Patients Undergoing IVF
The aim of this study is to determine if oocyte sorting for group culture using an artificial intelligence image analysis tool (MagentaTM) increases the usable blastocyst yield and subsequent pregnancy in patients undergoing IVF.
- Trial name
- NiOS (NCT06521372)
- Testing
- Magenta AI image analysis tool
- Where
- 3 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Ovation Fertility
Osteoarthritis, Hip, Coxarthrosis; Primary
Osseointegration of THA Grafted by PolyNASS (ACTISURF-CERAFIT® ) Versus Non-grafted THA (CERAFIT®)
The infection rate after Total Hip Arthroplasty (THA) is about 1%. It is a serious condition, with high morbidity, sometimes fatal, requiring costly treatment.
- Conditions
- Osteoarthritis, Hip, Coxarthrosis; Primary, Coxarthrosis; Secondary, Osteonecrosis; Aseptic, Idiopathic
- Trial name
- NCT03113981
- Testing
- Total Hip Arthroplasty
- Where
- 7 sites in France
- Volunteers
- 340 people
- Sponsor
- Societe ACTIVBIOMAT
Premature Ovarian Insufficiency, Infertility, Female
Ovarian PRP (Platelet Rich Plasma) Injection for Follicular Activation
The primary objective is to investigate the efficacy, defined as an increase in oocyte numbers upon ovarian stimulation, and safety of a single intra-ovarian PRP injection vs.
- Conditions
- Premature Ovarian Insufficiency, Infertility, Female, Sterility, Female, PRP
- Trial name
- OPIF (NCT05279560)
- Testing
- autologous PRP (platelet rich plasma), Saline solution (NaCL) Injection
- Where
- Germany
- Volunteers
- 114 people
- Sponsor
- University of Luebeck
Primary Uterine Infertility
Uterine Transplantation for the Treatment of Uterine Factor Infertility
This feasibility study aims to enroll ten subjects who will undergo deceased donor uterine transplantation at Cleveland Clinic. We estimate that fifty to one hundred patients with uterine factor infertility will need to be…
- Trial name
- NCT02573415
- Testing
- Uterus Transplant
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The Cleveland Clinic
Infertility, Female Infertility
Progesterone Luteal Support in Unexplained Infertility Management
The purpose of this study is to evaluate whether progesterone in women with unexplained infertility can increases live birth rate.
- Conditions
- Infertility, Female Infertility, Subfertility, Infertility Primary
- Trial name
- PLUIM (NCT07738068)
- Testing
- Utrogestan® 200 mg Soft Capsule
- Volunteers
- 640 people
- Sponsor
- Simone Broer
Infertility, Female, Polycystic Ovary Syndrome
Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort
Enrolling of 150 female patients of fertile age diagnosed with PCOS, insulin resistance, infertility, or mitochondrial disease, and the same number of age- and sex-matched controls are planned.
- Conditions
- Infertility, Female, Polycystic Ovary Syndrome, Insulin Resistance, Primary Ovarian Insufficiency
- Trial name
- POMODORI (NCT06167135)
- Where
- Hungary
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Recurrent Implantation Failure
ERA in Young Primary Infertile RIF Patients
This study aims to evaluate the clinical efficacy of transcriptome-based endometrial receptivity analysis (tb-ERA) and investigate the molecular mechanisms of abnormal receptivity in young women with unexplained recurrent…
- Trial name
- ERA (NCT07767240)
- Testing
- tb-ERA and personalized embryo transfer
- Where
- China
- Volunteers
- 400 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Ovarian Failure, Ovarian Insufficiency
Ovarian Tissue Allo-transplantation
Premature ovarian failure, also known as primary ovarian insufficiency (POI), or premature menopause, affects 1-2% of women under 40.
- Conditions
- Ovarian Failure, Ovarian Insufficiency, Menopause Ovarian Failure, Menopause, Premature
- Trial name
- NCT06673004
- Testing
- Ovarian tissue allo-transplantation
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Primary Ovarian Insufficiency, Azoospermia
Identifying Genome Variants in Non-Obstructive Azoospermia (NOA) or Primary Ovarian Insufficiency (POI)
Background: Infertility affects 1 in 6 people. Often, the causes of infertility are unknown. Treatments are successful in only about 50% of cases.
- Conditions
- Primary Ovarian Insufficiency, Azoospermia, Oligospermia
- Trial name
- NCT07357701
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hysteroscopy
Verbal Analgesia Versus Standard Care for Pain Control in Women With Primary Infertility Undergoing Office Hysteroscopy
Office hysteroscopy is a cornerstone in the diagnostic evaluation of infertile women, enabling direct visualization of the uterine cavity for identifying intrauterine pathology.
- Trial name
- NCT07325994
- Testing
- verbal analgesia, standard care
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Cairo University
Uterine Abnormality
Comparison of Ultrasound and Hysterosalpingography in Evaluation of Uterine Abnormality in Patients With Infertility
The leading issue that every couple is experiencing in present era is infertility and it has become the major problem worldwide. Many hormonal disorders, weight, diet, and uterine abnormalities contributes in infertility.
- Trial name
- NCT06763380
- Testing
- Ultrasound, ultrasound then hysterosalpingography
- Where
- Pakistan
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Superior University
Metabolic Diseases, Infertility
Study to Create Potential Cell-Based Therapies to Treat Human Disease and Disability
This is a research study in which your cells will be used for somatic cell nuclear transfer (SCNT), and/or genetic reprogramming research which may result in the production of stem cell lines.
- Trial name
- NCT00628199
- Testing
- Improving the scientific process of human cell reprogramming
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stanford University