Clinical trials: Primary Inguinal Hernia
Inguinal Hernia
Mesh Fixation With a Synthetic Glue in Primary Inguinal Hernia Repair
Prospective observational study with mesh fixation using FDA approved synthetic glue,glubran 2 and standard mesh fixation with stiches in primary inguinal hernia repair surgery.
- Trial name
- NCT02507830
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Rambam Health Care Campus
Hernia, Inguinal
Parietex Progrip Study
The objective of the study is to evaluate pain and disabling complications inducing social consequences in primary inguinal hernia ProGrip mesh repair compared to Lichtenstein repair with lightweight polypropylene mesh.
- Trial name
- NCT00827944
- Testing
- Parietex Progrip, Low weight polypropylene mesh
- Where
- 9 sites in Belgium, Germany and 3 more
- Volunteers
- 603 people
- Sponsor
- Medtronic - MITG
Inguinal Hernia
Antibiotic Prophylaxis in Mesh Repair of Inguinal Hernias
Inguinal hernia repairs is clean surgical procedures. However infection may be a concern when prosthetic materials are used. This prospective randomized study has been set to observe if antibiotic prohylaxis is of benefit in mesh…
- Trial name
- NCT01264003
- Testing
- sefazolin
- Volunteers
- 200 people
- Sponsor
- Diskapi Teaching and Research Hospital
Antibiotic Prophylaxis, Wound Infection
The Role of Antibiotic Prophylaxis in Lowering Wound Infection Rates Post-Open Repair of Primary Elective Groin Hernias in High-Risk Patients
This study aims to investigate the impact of antibiotic prophylaxis on reducing wound infection rates following open repair of primary elective groin hernias in high-risk patients.
- Conditions
- Antibiotic Prophylaxis, Wound Infection, Groin Hernia
- Trial name
- NCT06576154
- Testing
- Cefazolin 1000 MG
- Where
- Syria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aleppo
Primary Inguinal Hernia
Freedom Inguinal Hernia Repair System Study
The primary objective of this study is to evaluate patient quality-of-life (QOL) after inguinal hernia repair. "Carolinas Comfort Scale" (CCS) assessments will be held at regular intervals.
- Trial name
- NCT01984996
- Testing
- Freedom ProFlor Inguinal Hernia Implant
- Where
- 8 sites in United States, Austria and 1 more
- Volunteers
- 100 people
- Sponsor
- Insightra Medical, Inc.
Hernia, Inguinal, Men
Effects of Hernia Repair on Men's Sexual Functions
In the literature, there are several studies that compare Laparoscopic totally extraperitoneal hernia repair (TEP) with Lichtenstein hernia (LH) repair.
- Conditions
- Hernia, Inguinal, Men, Sexual Dysfunction
- Trial name
- NCT03326700
- Testing
- Inguinal Hernia Repair
- Volunteers
- 176 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Ventral Hernia Midline, Hernia Lumbar
Prospective Study of Minimally Invasive (Laparoscopic and Robotic) Hernia Repair (Incisional and Primary, Midline and Lateral, Not Inguinal)
The participating researchers register all adult patients (who have given informed written consent) scheduled for elective repair of an abdominal wall hernia (NOT inguinal hernias) via minimally invasive operation technique…
- Conditions
- Ventral Hernia Midline, Hernia Lumbar, Incisional Hernia Repair
- Trial name
- PROMISER (NCT07544238)
- Testing
- Minimally invasive hernioplastia
- Where
- Spain
- Volunteers
- 400 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Inguinal Hernia Unilateral, Complications of Surgical Procedures or Medical Care
Desarda Tissue Technique vs Lichtenstein Technique for Primary Inguinal Hernia Repair
This study aims to evaluate whether a surgical technique (Desarda) is superior to the commonly used surgical technique (Lichtenstein) in inguinal hernia repair concerning the occurrence of postoperative complications.
- Trial name
- HP-tis (NCT06650878)
- Testing
- Desarda, Lichtenstein
- Where
- Spain
- Volunteers
- 478 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
Hernia, Inguinal
PHS, Lichtenstein Mesh, and PerFixPlug for Primary Inguinal Hernia Repair - 3 Years Results
Three different techniques for the surgical repair of groin hernias are compared. Focus has been set on operation times, time to full return of functional abilities like walking in stairs etc, and if any technique has more…
- Trial name
- BOOP (NCT00580177)
- Testing
- Lichtenstein mesh, PerFix Plug®, Prolene® Hernia System
- Where
- Sweden
- Volunteers
- 472 people
- Sponsor
- Göteborg University
Primary Inguinal Hernia
Rives Technique Versus Lichtenstein Repair for Primary Inguinal Hernia
Lichtenstein technique, inserting a mesh over the inguinal cord in the neurological plane, is considered the standard of inguinal hernia repair, but it has 4% recurrence and 12% chronic postoperative pain.
- Trial name
- NCT03488342
- Testing
- Repair for primary inguinal hernia
- Where
- Spain
- Volunteers
- 600 people
- Sponsor
- Hospital Siberia-Serena
Indirect Inguinal Hernia
Comparison of Two Surgical Techniques for Indirect Inguinal Hernia Repair
This study will compare two ways of managing the hernia sac during laparoscopic surgery for an indirect inguinal hernia, a type of groin hernia. A hernia sac is a pouch of tissue that extends through the hernia opening.
- Trial name
- NCT07891845
- Testing
- Standard TAPP Repair With Complete Hernia Sac Dissection, TAPP Repair With Primary Abandon of the Sac
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Hitit University
Pain, Postoperative, Hernia, Inguinal
Surgical Pain After Inguinal Hernia Repair (SPAIHR)
The purpose of this study is to test whether pregabalin added to the standard of care with dosing starting preoperatively and continuing for 1 week post surgery will decrease the intensity of acute post-operative pain following…
- Trial name
- NCT00551135
- Testing
- Pregabalin
- Where
- 42 sites in United States, Australia and 4 more
- Volunteers
- 425 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Chronic Pain
Comparison of Mesh Fixation Wit Cyanoacrylate vs Suture in Inguinal Hernia Surgery
To compare fixation with glubran2 with suture during surgery por primary inguinal hernia. Hypothesis: Glue may induce less complications and chronic pain than suture
- Trial name
- UHU (NCT02197585)
- Testing
- Inguinal mesh hernioplasty
- Volunteers
- 150 people
- Sponsor
- Hospital del Mar
Hernia, Inguinal
Randomized Study of Open Mesh Repair in Local Anesthesia Versus Cost-optimized Laparoscopic Repair for Inguinal Hernia
The purpose of this study is to compare the frequency of long-term post operative pain after an open mesh repair ad modum Lichtenstein performed in local anaesthesia to that after an totally extraperitoneal laparoscopic repair…
- Trial name
- NCT01020058
- Testing
- Mesh repair for primary inguinal hernia
- Where
- 2 sites in Sweden
- Volunteers
- 384 people
- Sponsor
- Uppsala University Hospital
Primary Inguinal Hernia
The Effect of Preemptive Regional Anesthesia (TAP-block) on Acute and Chronic Pain After Transabdominal Preperitoneal Inguinal Hernia Repair (TAPP)
The study is devoted to the impact of preemptive regional Transversus abdominal plane block on the postoperative acute and chronic pain after elective Transabdominal preperitoneal (TAPP) inguinal hernia repair.
- Trial name
- ERA-TAPP (NCT06406959)
- Testing
- Transversus abdominal plane block (TAP block)
- Where
- Russia
- Volunteers
- 78 people
- Sponsor
- Pirogov Russian National Research Medical University
Primary Unilateral Inguinal Hernia
SIngle Port vs Standard TEP for Primary Inguinal Hernia Repair
This study is carried out to determine if laparoscopic inguinal TEP repair of the hernia using a mesh carried out with only 1 port (hole) results in the reduction of post- operative pain and use of painkillers, shorter hospital…
- Trial name
- LESSTEP (NCT02302937)
- Testing
- Group A will undergo laparoscopic TEP inguinal hernia repair with 3 ports (10 mm , and 2 ports of 5 mm ), Group B will undergo laparoscopic TEP inguinal hernia repair with a single port
- Where
- Singapore
- Volunteers
- 100 people
- Sponsor
- National University Hospital, Singapore
Inguinal Hernia
Efficacy Study of Tissucol/Tisseel Fibrin Sealant to Treat Inguinal Hernia
The purpose of the study is to evaluate mid and long term postoperative pain and further disabling complications in open inguinal hernia repair by Lichtenstein technique after mesh fixation with fibrin sealant (FS), compared to…
- Trial name
- NCT00306839
- Testing
- standardized Lichtenstein technique
- Where
- 6 sites in Belgium, Denmark and 4 more
- Volunteers
- 325 people
- Sponsor
- University of Milan
Primary Inguinal Hernia, Unilateral Hernia
The Efficacy of a Self-fixating Mesh in Unilateral Open Inguinal Hernia Repair
This study's objective is to assess the efficacy of a Self-fixating mesh in the surgical repair of unilateral inguinal hernia, which is becoming the new standard of care in open surgical repair of inguinal hernia.
- Conditions
- Primary Inguinal Hernia, Unilateral Hernia, Open Surgery
- Trial name
- NCT01596049
- Testing
- Self-fixating Mesh
- Where
- Israel
- Volunteers
- 7 people
- Sponsor
- Rambam Health Care Campus
Inguinal Hernia Unilateral, Pain Management
Comparing Opioids Vs NSAIDs for Postoperative Pain Management in Unilateral Primary Open Inguinal Hernia Repair
To control post-operative pain, multiple drugs are available, and in the western countries opioids are preferred. However, they have their own side effects, and so to reduce their dependence, multiple adjuncts are used.
- Trial name
- NCT06608056
- Testing
- Pain management after surgery
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Pakistan Air Force (PAF) Hospital Islamabad
Inguinal Hernia
LESS TEP vs. Three Port TEP for Inguinal Hernia Repair
This study aim to compare efficacy and safety of Laparoendoscopic single site total extraperitoneal inguinal hernia repair /LESS TEP/ and traditional total extraperitoneal hernia repair with 3 ports /TEP/.
- Trial name
- NCT04303182
- Testing
- Standard 3 port TEP, LESS TEP
- Where
- Bulgaria
- Volunteers
- 200 people
- Sponsor
- Sofia Med Hospital