Clinical trials: Primary Insomnia
Insomnia, Major Depression
Cortical GABA Concentrations in Insomnia
Disturbances in the amino acid neurotransmitter (AANt), gamma-amino butyric acid (GABA) function are hypothesized to contribute to the neurobiology of Major Depressive Disorder (MDD) and insomnia.
- Trial name
- NCT00765752
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Yale University
Insomnia
Effects of Insomnia on Simulated Driving (MK-0000-183-00)
This is a double-blind, parallel design study in elderly primary insomnia patients and demographically matched controls. The objectives if this study are primarily: 1.
- Trial name
- NCT01209728
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Insomnia
Intranasal Dexmedetomidine and Zolpidem for Treatment of Primary Insomnia
Insomnia is a significant public health burden, increasing work absenteeism and health care costs in a large proportion of the population. It causes altered cognition, emotional disturbances, and reduced quality of life.
- Trial name
- NCT05615727
- Testing
- Dexmedetomidine, Zolpidem
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Insomnia
A 2-Part Single Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2006
Part A: The purpose of this study is to evaluate the safety and tolerability of single oral doses of E2006 administered in the morning to healthy male and female subjects.
- Trial name
- NCT01463098
- Testing
- E2006 1.0 mg, E2006 2.5 mg, E2006 5.0 mg
- Where
- 2 sites in United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Primary Dysmenorrhea
Functional Exercises With Water Intake in Primary Dysmenorrhea
Dysmenorrhea and its associated symptoms are very common in women. In Pakistan, almost 78% of women report Primary Dysmenorrhea. This will be a randomized controlled trial with two parallel groups.
- Trial name
- NCT05285475
- Testing
- Exercise and Water Intake
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Dysmenorrhea Primary
Binaural Beats Dysmenorrhea And Sleep Quality
The research is a randomized controlled trial. The sample group will consist of 120 people; 60 participants will be included in the experimental group, and 60 will be included in the control group.
- Trial name
- NCT06838936
- Testing
- Binaural Beats
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Inonu University
Insomnia
Cognitive-Behavioural and Hypnotic Treatment of Chronic Primary Insomnia Among the Elderly
The present study examines the short- and long-term clinical efficacy of cognitive-behavior therapy and pharmacological treatment in patients suffering from late-life primary insomnia.
- Trial name
- NCT00295386
- Testing
- Cognitive behavior therapy (CBT), Zopiclone
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Bergen
Obstructive Sleep Apnea (OSA), Insomnia
Validating the Use of a Subjectively Reported Sleep Vital Sign
Sleep disorders are commonly under-recognized in the primary care setting and available screening tools are often are limited. The study inestigators hypothesize that the use of a novel subjective sleep vital sign (VS) will…
- Conditions
- Obstructive Sleep Apnea (OSA), Insomnia, Restless Leg Syndrome (RLS), Hypersomnia Type; Sleep Disorder
- Trial name
- SVS (NCT03018912)
- Testing
- Sleep VS
- Where
- United States
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Insomnia
Do People With Insomnia Sleep Better After Psychological Treatment?
The principal aim of the study is to evaluate if CBT for insomnia is associated with improvement in the PSG sleep of patients treated in primary care.
- Trial name
- NCT00170391
- Testing
- Quarter of an Hour rule
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Primary Insomnia
The Effects of Modafinil on Waking Function and on Sleep in Individuals With Primary Insomnia
This study examines how treatment with the drug modafinil, by itself or in combination with cognitive behavioral treatment for insomnia (CBT-I), may improve daytime functioning and/or diminish the severity of insomnia.
- Trial name
- NCT00124384
- Testing
- CBT-I, modafinil
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Insomnia
Agewise Project 3: Brief Behavioral Treatment of Insomnia in Primary Care
This project will test the efficacy of a brief, 2 session behavioral intervention for insomnia, as compared to an information-only condition.
- Trial name
- AW3 (NCT00177203)
- Testing
- Brief Behavioral Treatment of Insomnia or Information
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Primary Insomnia
A High Density EEG Comparison of Sleep Patterns in Insomnia
Insomnia, defined as a subjective report of difficulty initiating sleep, maintaining sleep, and/or non-restorative sleep, leads to significant daytime dysfunction and increased health risks.
- Trial name
- NCT01960452
- Testing
- Serial awakenings
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Sleep Disorders
Characteristics of Sleep Patterns in Young Adults With and Without Insomnia
This study will compare the symptoms, experiences, and laboratory sleep characteristics of young adults with and without insomnia.
- Trial name
- NCT00177216
- Testing
- Zolpidem, Escitalopram
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Insomnia
Evaluation of a Food Supplement on Sleep Quality
The purpose of this study is to evaluate the efficacy on sleep quality of a food supplement.
- Trial name
- Cyclamax (NCT00484497)
- Testing
- cyclamax
- Where
- France
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Persee Medica
Stress, Anxiety
Cereset Research Long-Term Healthcare Worker Study
Randomized, controlled study of long-term maintenance Cereset Research after an initial 4-session intervention bolus versus usual care control following an initial 4-session intervention bolus.
- Conditions
- Stress, Anxiety, Autonomic Dysregulation, Acoustic Stimulation
- Trial name
- LT-HW (NCT05994261)
- Testing
- Cereset Research
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Multiple Sclerosis, Quality of Life
Impact of Exercise on "Invisible" Symptoms and Quality of Life in Multiple Sclerosis Individuals
Patients with multiple sclerosis (MS) struggle on a daily basis with accompanying, "Invisible" symptoms like primary fatigue, pain and emotional-cognitive disorders.
- Conditions
- Multiple Sclerosis, Quality of Life, Motivation, Pain
- Trial name
- NCT03768830
- Testing
- Exercise training
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rijeka
Bladder Function
Pilot Trial in Sleep Laboratory Setting to Compare the Physiology of Night Time Bladder Function in Subjects With Overactive Bladder (OAB) Versus Subjects That Have Insomnia and Healthy Normal Subjects
This is an observational, physiology pilot study of subjects with overactive bladder, insomnia and normal subjects. No study drug will be given. All subjects will complete a one week sleep diary and a 3-day bladder diary.
- Trial name
- Nocturia Plt 1 (NCT01029015)
- Testing
- cystometry, polysomnography
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Health Personnel, Stress
Cereset Research In Healthcare Workers During COVID-19
The purpose of this study is to evaluate the use of Cereset Research to improve the symptoms of stress in healthcare workers in an open label, waitlist controlled pilot clinical trial, during the period of COVID-19.
- Conditions
- Health Personnel, Stress, Anxiety, Insomnia
- Trial name
- NCT04682197
- Testing
- Cereset Research
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Nausea, Gastroparesis
Cereset Research For Chronic Nausea
This study will explore the use of Cereset Research for symptoms associated with refractory chronic nausea in patients with gastroparesis (GP) in a randomized, clinical trial.
- Conditions
- Nausea, Gastroparesis, Stress, Anxiety
- Trial name
- NCT05229107
- Testing
- Cereset Research
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Tension Headaches, Stress
Temple Massager System Study in Women Ages 35-65
The goal of this observational study is to learn how the Temple Massager System affects stress, emotional wellbeing, sleep, and quality of life in women aged 35 to 65.
- Conditions
- Tension Headaches, Stress, Sleep Quality, Quality of Life
- Trial name
- NCT07639658
- Testing
- Temple Massager System
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Meisch Temple Massager, Inc.