Clinical trials: Primary Neoplasm
Heart Failure
Point of Care Artificial Intelligence Tool for Heart Failure Diagnosis
Abbreviations/acronyms: DUO-EF = prediction of ejection fraction (EF) using the Eko-DUO digital stethoscope algorithm HF = heart failure HFrEF = heart failure with reduced ejection fraction COVID-19 = coronavirus disease 2019 Eko…
- Trial name
- DUO-EF-19 (NCT04601415)
- Testing
- ECG from handheld device
- Where
- United Kingdom
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Cervical Cancer, Cervical Dysplasia
Acceptability and Efficacy of Self-sampling for Cervical Cancer Screening: A Pilot Study
In Singapore, the current cervical cancer screening uptake among women in Singapore has remained at low 50% since its introduction in 2004.
- Conditions
- Cervical Cancer, Cervical Dysplasia, Human Papillomavirus Infection
- Trial name
- NCT03813576
- Testing
- Self-collected HPV vaginal swab
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Oral Cancer
Web-based Education on Oral Cancer for Primary Care Physicians in Ohio
Objective: The experimental design is a one-site, randomized experimental web-based educational feasibility intervention trial, with approximately 50% primary care physicians (PCPs) in the intervention group and approximately 50%…
- Trial name
- NCT01424358
- Testing
- Web-based Educational Intervention
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Creighton University
Depression, Incontinence
A Casefinding and Referral System for Older Veterans Within Primary Care
Underdiagnosis and undertreatment of elderly persons remains a widespread problem. While many innovative geriatric care programs exist within VHA, we still lack a systematic process for identifying at-risk elders from the larger…
- Conditions
- Depression, Incontinence, Cognitive Impairment
- Trial name
- NCT00012740
- Testing
- Casefinding and Referral System
- Where
- United States
- Volunteers
- 792 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Prostate Cancer
PSA TOOL for Prostate Cancer Screening Discussions
The study team created a tool to help identify patients who may benefit from shared decision making in the primary care setting. This tool is a guide to aid in decision making for prostate cancer screening.
- Trial name
- NCT03135444
- Testing
- PSA TOOL, Revised PSA TOOL, Informal Interview
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Dental Restoration
Comparative Clinical Evaluation of BioFlx, Zirconia, and Stainless-Steel Crowns in Primary Molars
This study will be conducted to: Evaluate and compare the clinical success, periodontal changes, and wear of antagonist teeth for three types of prefabricated crowns in primary molars: BioFlx crowns, Zirconia crowns, and…
- Trial name
- NCT06450093
- Testing
- Preformed stainless steel crown., Preformed zirconia crown, Preformed BioFlx crown
- Where
- Egypt
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Physical Activity, Life Style
Cardiovascular Disease Prevention Strategies for High-risk Urban Sedentary Employees in Karachi, Pakistan
Heart diseases and other non-communicable diseases are serious health issues in countries like Pakistan. Many people who work in offices, like bank employees, sit for more than 8 hours a day.
- Conditions
- Physical Activity, Life Style, Dietary Habits, Cardiovascular Diseases
- Trial name
- m-LIfE (NCT06981247)
- Testing
- m-LIfE: mobile based lifestyle intervention for employees to increase their physical activity and promote healthy diet., Routine care arm
- Where
- Pakistan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Primary Hyperoxaluria
Primary Hyperoxaluria Mutation Genotyping
This study will help us determine whether certain genetic mutations, more than others, are a cause of more severe disease in Primary Hyperoxaluria.
- Trial name
- NCT00589225
- Testing
- Genetic Analysis
- Where
- United States
- Volunteers
- 902 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Endodontically Treated Teeth
Endodontic Management of Primary Molars
The purpose of this study was to describe the clinical and radiological outcome of root canal treatment with OrthoMTA in primary second molars without successors in which traditional root canal treatment with gutta-percha could…
- Trial name
- NCT04691050
- Testing
- OrthoMTA (BioMTA)
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Dental Caries, Dental Occlusion
Occlusal Impact of Hall Crowns in Primary Molars
Hall Technique is a non-invasive restorative approach for managing carious primary molars, increasingly used in pediatric dentistry due to its simplicity and patient tolerance.
- Conditions
- Dental Caries, Dental Occlusion, Pediatric Dentistry
- Trial name
- NCT07134114
- Testing
- Hall Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
GLAUCOMA 1, OPEN ANGLE, D (Disorder)
Spectral Domain Optical Coherence Tomography Analysis for Glaucoma
The aim of this study is to examine whether there is a difference in macular ganglion cell complex thickness and retinal nerve fiber layer thickness in early-stage Primary open angle glaucoma and normal tension glaucoma with…
- Trial name
- NCT01612416
- Testing
- RS-3000 OCT measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Inonu University
Healthy, Focal Dystonias
Role of Dopamine Receptors in Primary Focal Dystonias
Dystonia is a disabling movement disorder characterized by repetitive patterned or sustained muscle contractions causing twisting or abnormal postures that may afflict 250,000 people in the U.S.
- Trial name
- NCT01373840
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Respiratory Syncytial Virus
A Study of mRNA-1345 Following a Primary Dose of a Licensed Protein Subunit Respiratory Syncytial Virus (RSV) Vaccine in Adult Participants ≥60 Years of Age
The purpose of this study is to evaluate safety, tolerability and immunogenicity of mRNA-1345 in participants who have been previously vaccinated with either Arexvy or Abrysvo at least 12 months prior to enrollment, are medically…
- Trial name
- NCT07117487
- Testing
- mRNA-1345
- Where
- 11 sites in United States
- Volunteers
- 507 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
HIV Infections, Sexually Transmitted Diseases
Parents Matter!: Interventions to Promote Effective Parent-Child Communication
Parents Matter is a community-based project whose goal it is to develop and test an intervention designed to promote effective parent-child communication about sexuality in order to promote sexual health among adolescents.
- Conditions
- HIV Infections, Sexually Transmitted Diseases, Pregnancy
- Trial name
- NCT00137943
- Testing
- Full Parent communication intervention, Brief Parent Communication Intervention, Control Parent Intervention
- Where
- 3 sites in United States
- Volunteers
- 2,210 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Dental Caries, Tooth Decay
Zirconia-based Primary Anterior Crowns With Retention Grooves Versus Without Retention Grooves
The purpose of this research study is to test the effectiveness of two different crowns/caps on teeth for restoration of primary anterior teeth.
- Trial name
- NCT06354647
- Testing
- Zirconia-based primary anterior crowns with retention grooves, Zirconia-based primary anterior crowns without retention grooves
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Haemophilus Influenzae Type b, Neisseria Meningitidis
3 Formulations of Hib-MenCY-TT Vaccine & 1 Formulation of Hib-MenC-TT Vaccine Compared to Licensed Meningococcal Serogroup C Conjugate Vaccine, Each Administered at 2,3,4 Mths of Age
This study evaluated the safety and immunogenicity of 3 formulations of Hib-MenCY-TT vaccine and 1 formulation of Hib-MenC-TT vaccine compared to a control group receiving licensed meningococcal serogroup C conjugate vaccine…
- Trial name
- NCT00129116
- Testing
- Hib-MenCY-TT vaccine, Hib-MenC-TT vaccine, Menjugate ®
- Where
- 26 sites in Belgium, Germany
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Primary Hypercholesterolemia
Evaluate the Pharmacokinetics and Safety of HCP1306 and Co-administration of HGP0816, HGP1404 in Healthy Male Volunteers
The purpose of this study is to evaluate Pharmacokinetic Properties and Safety after administration of HCP1306 tablet and Co-administration of HGP0816 tablet, HGP1404 tablet in the healthy adults.
- Trial name
- NCT02941848
- Testing
- HGP0816, HGP1404, HCP1306
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Accidental Falls, Osteoporosis
Prevention of Falls and Its Consequences in Elderly People
Falls are an important risk factor for fragility fractures. Both are associated with the ageing process and as they rise also increase the risk of mortality, disability and dependency.
- Trial name
- PRECIOSA (NCT02617303)
- Testing
- OTAGO's exercises, COMMON PRACTICE
- Where
- 11 sites in Spain
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Carious Anterior Teeth
Zinc Oxide-Ozonated Olive Oil vs Metapex in Primary Anterior Teeth
This randomized clinical trial compares zinc oxide-ozonated olive oil and Metapex as root canal filling materials in primary anterior teeth of children aged 3-5 years.
- Trial name
- ZO-OOO (NCT07265089)
- Testing
- Zinc Oxide-Ozonated Olive Oil, Metapex
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Barrett Esophagus, Barrett's Esophagus Without Dysplasia
Evaluation of Tethered Capsule Endomicroscopy as a Screening Tool for Barrett's Esophagus in the Primary Care Setting
The investigators will conduct a large study in the primary care clinic to determine the feasibility of using tethered capsule endomicroscopy as a screening method for Barrett's esophagus (BE) in the primary care practice…
- Conditions
- Barrett Esophagus, Barrett's Esophagus Without Dysplasia, Barretts Esophagus With Dysplasia
- Trial name
- NCT04561791
- Testing
- Tethered Capsule Endomicroscopy
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
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