Clinical trials: Primary Neoplasm
Obesity
Effectiveness of an Eight Week Online Mediterranean Based Diet
This research is examining whether an 8-week online nutritional programming based on a Mediterranean diet can achieve meaningful increase intake of a Mediterranean based diet and improvements in measures of body weight and…
- Trial name
- NCT01532258
- Testing
- Go! Foods for You without Weekly MA Support., Go! Foods for You with Weekly MA Support.
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Insomnia
A 2-Part Single Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2006
Part A: The purpose of this study is to evaluate the safety and tolerability of single oral doses of E2006 administered in the morning to healthy male and female subjects.
- Trial name
- NCT01463098
- Testing
- E2006 1.0 mg, E2006 2.5 mg, E2006 5.0 mg
- Where
- 2 sites in United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Hereditary Angioedema (HAE)
Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetics of Recombinant Human C1 Esterase Inhibitor in Healthy Adult Subjects
This trial is looking to gain information about the safety and tolerability of an investigational treatment (SHP623) in healthy adult volunteers.
- Trial name
- NCT02663687
- Testing
- Recombinant human C1 esterase inhibitor, SHP623
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Shire
Healthy
Dermatological Evaluation of Topic Compatibility-Dermacyd Tina Gel Tangerina Mix
The purpose of this study is to demonstrate the absence of irritation potential (primary dermic irritability and cumulated dermic irritability) and allergy (sensibilization) of the product Dermacyd Tina Gel Tangerina Mix
- Trial name
- NCT00669058
- Testing
- Lactic acid (Dermacid)
- Where
- Brazil
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Sanofi
Cervical Cancer
Dissemination of Cervical Cancer Screening to Primary Care Physicians in Underserved Communities
Primary care physicians have an important role to play in the delivery of cancer prevention and detection services to patients. Face-to-face counseling of physicians, called academic detailing, involves a brief and focused…
- Trial name
- NCT00629993
- Testing
- Academic Detailing
- Where
- United States
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Columbia University
ALL, Adult
Optimising Pharmacist-led Medication Reviews in Primary Care
An increasing number of people are diagnosed with long-term conditions and are prescribed medicines to manage these conditions. Medication reviews (MRs) are used to optimise medicines, improve health outcomes, and decrease…
- Trial name
- OPen (NCT05928104)
- Testing
- Medication review
- Where
- 3 sites in United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Crestal Bone Resorption, Implant Primary Stability
Clinical Evaluation Of Dental Implants Stability Placed In Healed Bony Sites Following Over-drilling Compared To Conventional-Drilling Protocol
Clinical Evaluation Of Dental Implants Stability Placed In Healed Bony Sites Following Over-drilling Compared To Conventional-Drilling Protocol
- Conditions
- Crestal Bone Resorption, Implant Primary Stability, Implant Osseointegration
- Trial name
- RCT (NCT03250949)
- Testing
- implant site over drilling protocol
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Azhar ALI ELSAYED SELEEM
Colorectal Neoplasms, Colonic Polyps
Study of Flat Polyp Detection Using New Narrow Band Imaging (NBI) Compared to White Light Colonoscopy - The FIND FLAT Colonoscopy Study
We hypothesize that high definition narrow band imaging (NBI) colonoscopy compared to high definition white light colonoscopy will detect an increased number of nonpolypoid (flat and depressed) colorectal neoplasm.
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Colorectal Cancer
- Trial name
- NBI (NCT01310699)
- Testing
- Olympus Colonoscope CFHQ190AL
- Where
- 3 sites in United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Cancer
Cancer Prevention and Early Detection Among the Homeless Population: The Health Navigator Model
Prevention and early detection are key for the decrease of cancer-related mortality. However, socially deprived population groups don't have the privilege of unburdened access to the healthcare system.
- Trial name
- CANCERLESS (NCT05406687)
- Testing
- Health Navigator Model
- Where
- 18 sites in Austria, Greece and 2 more
- Volunteers
- 654 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Bone; Disorder, Development and Growth
Effects of Oral vs. Non-oral Contraceptives on the GH/IGF-1 Axis
This study will determine whether the negative effects of combined oral contraceptive (COC) therapy on the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and bone turnover are dependent on the route of administration…
- Trial name
- NCT02367833
- Testing
- Combined Oral Contraceptive, Transdermal Contraceptive, Contraceptive Vaginal Ring
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Penn State University
Myocardial Infarction, Percutaneous Coronary Intervention
Circulating PRCP in STEMI Patients Undergoing Primary PCI
Purpose: The purpose of this study is to evaluate the impact of acute ST-segment elevation myocardial infarction (STEMI) and primary percutaneous coronary intervention (PCI) on circulating prolylcarboxypeptidase (PRCP) level and…
- Conditions
- Myocardial Infarction, Percutaneous Coronary Intervention, PRCP
- Trial name
- NCT02772133
- Testing
- Primary PCI
- Where
- 4 sites in China
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Depression, Mental Disorder
Digital Training for Non-Specialist Health Workers to Deliver a Brief Psychological Treatment for Depression
The purpose of this 3-arm randomized controlled trial is to compare two forms of digital training (i.e., low-intensity and high-intensity) with traditional face-to-face training of non-specialist health workers to deliver an…
- Conditions
- Depression, Mental Disorder, Psychological
- Trial name
- ESSENCE (NCT04157816)
- Testing
- Face-to-Face Training, Digital Training, Coaching Support
- Where
- India
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Fissure Sealant
The Effect of Different Deproteinizing Agents on the Clinical Success of Fissure Sealants in Primary Teeth
Investigation of the effect of deproteinization agents on the clinical success of non-invasive fissure sealant application, which is a non-invasive method used to prevent caries formation or to stop the progression of initial…
- Trial name
- NCT07003958
- Testing
- application of deproteinization agents
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Lyme Disease, Tick-Borne Diseases
Lyme Disease Prevention Program
This is a large study of an educational program on Lyme disease prevention for passengers on ferry boats going to Nantucket Island during the period from Memorial Day until Labor Day.
- Trial name
- NCT00000432
- Testing
- Education about disease prevention
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Fibrinogen Abnormality, Telomere Length, Mean Leukocyte
Pediatric ACEs Screening and Resiliency Study
Stressful and traumatic experiences in childhood (Adverse Childhood Events, or ACEs) have been associated with poor health outcomes that extend into adulthood.
- Conditions
- Fibrinogen Abnormality, Telomere Length, Mean Leukocyte, Atopic, Acute Infection
- Trial name
- PEARLS (NCT04182906)
- Testing
- Care Coordination, Resiliency Clinic, Usual Care
- Where
- United States
- Volunteers
- 555 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Healthy Volunteers, Tension-type Headache
A Study to Describe Pain Intensity, Pain Relief and Safety of Neosaldina in the Treatment of Tension-type Headaches (TTH) in Healthy Participants
The purpose of this study is to describe pain relief in TTH with Neosaldina treatment.
- Trial name
- NCT03666858
- Where
- 5 sites in Brazil
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Takeda
Varicella
An Open-labelled Clinical Trial of Live Attenuated Varicella Vaccines to Evaluate the Immunity Persistence After Primary Immunization and Safety and Immunogenicity After the Booster Immunization
This is an open-labelled clinical trial of live attenuated varicella vaccines manufactured by Sinovac (Dalian) Vaccine Technology Co., Ltd .The purpose of this study is to evaluate the immunity persistence of the single-dose…
- Trial name
- NCT05150392
- Testing
- Investigational live attenuated varicella vaccine
- Where
- China
- Volunteers
- 1,193 people, healthy volunteers welcome
- Sponsor
- Sinovac (Dalian) Vaccine Technology Co., Ltd.
Vital Pulp Therapies, Indirect Pulp Cap
Vital Pulp Treatment in Primary Teeth
In primary teeth, decay that is near the pulp (tooth nerve)is treated with either a pulpotomy or indirect pulp treatment if the tooth is not going to be extracted A pulpotomy involves removing the top 1/2 of the pulp, placing a…
- Conditions
- Vital Pulp Therapies, Indirect Pulp Cap, Pulpotomy
- Trial name
- NCT02298504
- Testing
- Mineral Trioxide Aggregate, Biodentin, Vitrebond
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Migraine, Magnesium, Pediatric
Serum Magnesium Level and Pediatric Migraine
Aim: The purpose of this study is to compare serum magnesium levels between patients with migraine and a control group and to examine the relationship between the frequency and duration of attacks in patients with migraine and…
- Trial name
- Migraine (NCT06274255)
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mersin University
Mental Illness Persistent, Cardiovascular Prevention
Cardiac Rehabilitation for Cardiovascular Risk Reduction in People With Severe and Persistent Mental Illness
The goal of this prospective, randomized trial is to explore the link between cardiovascular disease and mortality in individuals with severe and persistent mental illness (SPMI).
- Trial name
- NCT05659498
- Testing
- Cardiac Rehabilitation Program
- Where
- Canada
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Lady Davis Institute
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