Clinical trials: Primary Neoplasm
Infections, Streptococcal
Primary and Booster Vaccination Study With Pneumococcal Vaccine GSK1024850A and Prophylactic Antipyretic Treatment
The aim of the current study is to determine whether ibuprofen, given as immediate or delayed prophylactic antipyretic treatment in a standardized manner, significantly impacts the immune response in children receiving primary…
- Trial name
- NCT01235949
- Testing
- GSK1024850A (SynflorixTM), Infanrix hexa, Infanrix-IPV/Hib
- Where
- 23 sites in Romania
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Health Services, Comorbidity
Ambulatory ICU Study for Medically and Socially Complex Patients
This is a prospective randomized wait-list control study to determine whether a stand-alone, co-located team of physician, mental health behaviorist, and care coordinators with decreased panel size (aka "intensive primary care")…
- Conditions
- Health Services, Comorbidity, Primary Health Care
- Trial name
- SUMMIT (NCT03224858)
- Testing
- SUMMIT intervention, Enhanced usual care
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
HIV Infections
Workplace-based HIV Self-testing Among Men in Uganda (WISe-Men)
This study seeks to determine whether workplace delivery of HIV self-testing will lead to an increase in uptake of HIV testing and subsequent linkage to care or prevention services among men in Uganda.
- Trial name
- NCT04164433
- Testing
- Oral HIV Self-Test (OraQuick)
- Where
- 2 sites in Uganda
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- Makerere University
Dental Caries in Children
Impact of Oral Health Program on Al-Lith Children's KAP
Dental caries remains a significant global public health issue, particularly affecting children's health, development, and well-being, with inadequate knowledge, attitudes, and practices around oral health exacerbating these…
- Trial name
- NCT07009015
- Testing
- The oral health education intervention program
- Where
- Malaysia
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Climate Change Awareness
Climate Change Training for Primary Health Care Workers
Improving climate change awareness among primary care nurses is of great importance for the future of the health sector. Increasing this awareness enables primary care workers to combat environmental health problems more…
- Trial name
- NCT07809035
- Testing
- scenario-based climate change awareness training.
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Orthostatic Hypotension
Assessment of Hand-grip in the Prevention of Postural Orthostatic Hypotension
The study is aimed to assess the efficacy of hand-grip in preventing orthostatic hypotension in 20 patients diagnosed with autonomic failure. Five healthy subjects will be studied for comparison.
- Trial name
- NCT01521221
- Testing
- Hand grip maneuver
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Migraine
Longitudinal Changes of Brain Functional Connectivity in Migraine
The purpose of this study is to identify a core fMRI feature that determines migrainous brain and plastic fMRI features that changes with longitudinal courses of migraine.
- Trial name
- NCT03487978
- Testing
- resting-state functional MRI
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
COVID-19, COVID-19 Acute Respiratory Distress Syndrome
The Effect of Listening to Music During CPAP on the Agitation Levels and Compliance.
Aim: This study was conducted to determine the effect of listening to music during CPAP on the agitation levels of intensive care patients who underwent CPAP due to COVID-19 and their compliance with the treatment.
- Trial name
- NCT05102084
- Testing
- Listening to music with a bluetooth headset to patients receiving CPAP support
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- SÜMEYYE BİLGİLİ
Obesity
Weight Loss in Primary Care With Targeted Education and Frequent Follow Ups
The investigators will be recruiting patients in the primary care setting to enroll a weight loss program where they will be seen every 2 weeks for 3 months, and then every month for 3 months, and the investigators will implement…
- Trial name
- NCT05141084
- Testing
- Education, lifestyle
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Alcohol Drinking, Sex Behavior
Alcohol and Implicit Process in Sexual Risk Behavior in MSM
The current study is the first empirical investigation that directly addresses the correspondence between responses regarding indicators of risky sexual behavior while under the influence of alcohol in the laboratory and the…
- Conditions
- Alcohol Drinking, Sex Behavior, Men
- Trial name
- NCT03361384
- Testing
- Alcohol
- Where
- 3 sites in United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Syracuse University
Primary Insomnia
The Effects of Modafinil on Waking Function and on Sleep in Individuals With Primary Insomnia
This study examines how treatment with the drug modafinil, by itself or in combination with cognitive behavioral treatment for insomnia (CBT-I), may improve daytime functioning and/or diminish the severity of insomnia.
- Trial name
- NCT00124384
- Testing
- CBT-I, modafinil
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Dysmenorrhea Primary
A Study of Diclofenac Gel in Women With Primary Dysmenorrhea
The goal of this clinical trial is to compare 1% and 3% diclofenac gel (DARE-PDM1) to placebo in women with symptomatic primary dysmenorrhea.
- Trial name
- DARE-PDM1 (NCT05752526)
- Testing
- Diclofenac 1%, Diclofenac 3%
- Where
- Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Daré Bioscience, Inc.
Pulmonary Fibrosis of Any Cause, Primary Supporters/Caretakers of Patients With Pulmonary Fibrosis
Pulmonary Fibrosis Contact Registry
As the name states, contact registries securely store contact information from groups of reasonably well-characterized patients (or primary supporters/caregivers) who are interested in being informed about ongoing or future…
- Trial name
- NCT01935726
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Jewish Health
Poverty, Income
addressInG iNcome securITy in Primary carE
Social processes that impact the health of individuals have been labeled the social determinants of health (SDOH). These are "the conditions in which people are born, grow, live, work and age.
- Conditions
- Poverty, Income, Social Determinants of Health
- Trial name
- IGNITE (NCT02459184)
- Testing
- Income Security Health Promotion
- Where
- Canada
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Parkinson's Disease (PD), Parkinsonism
Identifying Biomarkers of Parkinson's Disease Using Magnetic Resonance Imaging (MRI)
This study is designed to determine if magnetic resonance imaging (MRI) measures can be used to diagnose and monitor the progression of Parkinson's disease (PD) while distinguishing between PD and parkinsonisms [conditions that…
- Conditions
- Parkinson's Disease (PD), Parkinsonism, Progressive Supranuclear Palsy (PSP), Multiple System Atrophy (MSA)
- Trial name
- NCT01888185
- Where
- United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Exfoliation Syndrome
Central Corneal Thickness in Glaucoma
The purpose of this study is to compare the central corneal thickness measurement in patients with exfoliation syndrome, exfoliative glaucoma, primary open-angle glaucoma, ocular hypertension and normal controls and to evaluate…
- Trial name
- NCT01023997
- Where
- Greece
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Fibromyalgia, Primary
An Eight Week, Double-Blind Efficacy Study of Armodafinil Augmentation to Alleviate Fibromyalgia Fatigue
Armodafinil (NuvigilTM) is an isomer of a drug currently approved by the FDA for the treatment of fatigue secondary to narcolepsy, sleep apnea, and shift work sleep disorder called modafinil (ProvigilTM).
- Trial name
- NCT00678691
- Testing
- armodafinil
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Obesity (Disorder)
AI-INFORMED PEER-MENTORING BEHAVIORAL INTERVENTION FOR OBESITY AND CARDIOVASCULAR DISEASE PRIMARY PREVENTION IN YOUTH
The goal of this clinical trial is to learn if an AI-based peer-mentoring works to prevent obesity in adolescents and young adults.
- Trial name
- PeerMentorOBCV (NCT07505459)
- Testing
- AI-informed behavioral intervention, Standard behavioral intervention, Health Education
- Where
- 3 sites in Greece, Italy and 1 more
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Aikaterini Karaivazoglou
B Acute Lymphoblastic Leukemia With t(v;11q23.3); KMT2A Rearranged, Recurrent B Acute Lymphoblastic Leukemia
CD19-Specific T Cells Post AlloSCT
This phase I trial investigates the side effects and best dose of CD19 positive (+) specific CAR-T cells in treating patients with CD19+ lymphoid malignancies, such as acute lymphoblastic leukemia, non-Hodgkin lymphoma, small…
- Conditions
- B Acute Lymphoblastic Leukemia With t(v;11q23.3); KMT2A Rearranged, Recurrent B Acute Lymphoblastic Leukemia, Recurrent Chronic Lymphocytic Leukemia, Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
- Trial name
- NCT03579888
- Testing
- Autologous CD19-CD8-CD28-CD3zeta-CAR-mbIL15-HER1t T Cells, Cyclophosphamide, Fludarabine
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Pediatric Hypertension
Boosting Primary Care Awareness and Treatment of Childhood Hypertension
The proposed research, building on an ongoing AHRQ-funded research project to prevent pediatric diagnostic errors in primary care (R01HS023608) and using a prospective, cluster-randomized, stepped wedge design, will investigate…
- Trial name
- BP-CATCH (NCT03783650)
- Testing
- Control condition, QIC with PCP and without subspecialist, QIC with Subspecialist
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
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