Clinical trials: Primary Spontaneous Pneumothorax
Pneumothorax
Effect of Dissecting of The Inferior Pulmonary Ligament on Postoperative Pulmonary Reexpansion and Recurrence
This subject analysis of the influence of the dissociating inferior pulmonary ligament on pulmonary reexpansion and recurrence in the treatment of primary spontaneous pneumothorax by video assisted thoracic surgery.
- Trial name
- NCT02558608
- Testing
- DIPL, WR, thoracoscopic surgery
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Chinese Medical Association
Pneumothorax
Intrapleural Minocycline After Simple Aspiration for the Prevention of Primary Spontaneous Pneumothorax
The estimated recurrence rate of primary spontaneous pneumothorax is 23-50% after the first episode, and the optimal treatment remains unknown.
- Trial name
- NCT00418392
- Testing
- Simple aspiration with minocycline pleurodesis, simple aspiration
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Primary Spontaneous Pneumothorax
Effect of Tetracycline Pleurodesis on Prevention of Primary Spontaneous Pneumothorax Recurrence
Primary spontaneous pneumothorax (PSP) defines as presence of air in chest cavity occurs most commonly in young, tall, and smoker men without underlying lung disease. Trends for PSP treatment tend toward more invasive procedures.
- Trial name
- NCT03634605
- Testing
- Chemical pleurodesis, Tetracycline Topical Ointment, Normal saline
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Isfahan University of Medical Sciences
Pneumothorax
Pathogenesis of Primary Spontaneous Pneumothorax
Primary spontaneous pneumothorax most commonly occurs in young, tall, lean males. The estimated recurrence rate is 23-50% after the first episode and increases to 60% after the second pneumothorax.
- Trial name
- NCT01135004
- Testing
- Thoracoscopic bullectomy
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Pneumothorax
Chest Tube Drainage or Thoracoscopic Surgery for Failed Aspiration of Spontaneous Pneumothorax
We hypothesize that VATS is more effective than CTD for management of primary spontaneous pneumothorax with aspiration failure. To this end, we will compare two groups of patients who had experienced unsuccessful aspiration of…
- Trial name
- NCT00713362
- Testing
- Video-assisted thoracoscopic surgery, chest tube drainage
- Where
- 2 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Pneumothorax, Spontaneous
Prospective Study on Clinical Outcomes of Spontaneous Pneumothorax
Pneumothorax can be fatal if treatment is delayed or the pneumothorax is refractory. However, the mortality rates and their risk factors were mainly reported from retrospective studies, and local data regarding the mortality of…
- Trial name
- NCT05397717
- Testing
- observational
- Where
- Hong Kong
- Volunteers
- 349 people
- Sponsor
- Chinese University of Hong Kong
Pneumothorax Spontaneous Primary
Outpatient Management of Primary Spontaneous Pneumothorax: Pigtail Catheter With Unidirectional Valve vs. Exsufflation, Randomized Prospective Study
The management of large spontaneous pneumothorax is not consensual. Current practice involves placement of a Fuhrman catheter connected to a one-way valve, with outpatient monitoring in pneumology consultation.
- Trial name
- PNEUM-AMBU (NCT03691480)
- Testing
- Fuhrman catheter insertion, Three-way stopcock open, Manual aspiration
- Where
- 5 sites in France
- Volunteers
- 148 people
- Sponsor
- Rennes University Hospital
Pneumothorax
Intrapleural Minocycline After Aspiration of Spontaneous Pneumothorax
The estimated recurrence rate of primary spontaneous pneumothorax is 23-50% after the first episode, and the optimal treatment remains unknown.
- Trial name
- NCT00839553
- Testing
- Intrapleural Minocycline application
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Far Eastern Memorial Hospital
Malignant Pleural Effusions, Recurrent Pleural Effusions
A Comparative Study of the Safety and Efficacy of Face Talc Slurry and Iodopovidone for Pleurodesis
Pleurodesis is a technique used to fuse the two layers of the lining over the lung. This is done to get rid of collections of fluid or air in this space.
- Conditions
- Malignant Pleural Effusions, Recurrent Pleural Effusions, Primary Spontaneous Pneumothorax, Secondary Spontaneous Pneumothorax
- Trial name
- NCT00430664
- Testing
- Pleurodesis with either talc or iodopovidone
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pneumothorax Spontaneous Secondary
PRP in 2ry Spontaneous Pneumothorax
secondary spontaneous pneumothorax patients will be enrolled ,all of them will receive PRP with different doses and schedules
- Trial name
- NCT03830645
- Testing
- Platelet Rich Plasma
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Zagazig University
Pneumothorax
Additional Minocycline Pleurodesis After Thoracoscopic Procedures for Primary Spontaneous Pneumothorax
To test if additional minocycline pleurodesis after thoracoscopic procedures can reduce the rates of ipsilateral recurrence for patients with primary spontaneous pneumothorax.
- Trial name
- NCT00154895
- Testing
- intrapleural minocycline instillation
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Pneumothorax
Pleurectomy Versus Pleural Abrasion in Patients With Spontaneous Pneumothorax
Pneumothorax refers to air in the pleural cavity (i.e. interspersed between the lung and the chest wall).1 Primary spontaneous pneumothorax (PSP) mostly occurs in healthy individuals without an apparent cause, probably due to the…
- Trial name
- NCT05407974
- Testing
- pleurectomy
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pneumothorax
Chronic Pain After Video-assisted Thoracoscopic Surgery (VATS) Surgery for Pneumothorax
The study will investigate characteristics of chronic pain after VATS surgery with two different sizes of videoscopic equipment.
- Trial name
- NCT00969423
- Testing
- 5mm videoscope, 10mm videoscope
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Primary Spontaneous Pneumothorax
Autologous Blood Patch for Primary Spontaneous Pneumothorax
The purpose of this study is to show that treatment with prophylactic autologous blood patch (ABP) after management of primary spontaneous pneumothorax (PSP) is feasible, reduces the incidence of prolonged air leaks, and reduces…
- Trial name
- NCT06088901
- Testing
- Autologous Blood Patch
- Where
- United States
- Sponsor
- Rush University Medical Center
Primary and Secondary Spontaneous Pneumothorax
Does Non-Steroidal Anti-inflammatory Drugs Decrease the Quality of Pleurodesis After Mechanical Pleural Abrasion/Pleurectomy for Treatment of Pneumothorax?
Investigators aim to assess if NSAIDs affect the quality of pleurodesis resulting from mechanical pleurodesis (open surgery or VATS) regarding : Primary outcome: Recurrence of pneumothorax in 6 monthes.
- Trial name
- NCT06467318
- Testing
- Paracetamol, NSAID, Paracetamol
- Where
- Egypt
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Primary Spontaneous Pneumothorax
Study Compares Pneumothorax Recurrence: Absorbable Mesh vs. Pleurectomy in Primary Spontaneous Pneumothorax.
This is a prospective, randomized controlled trial (pilot study) that aims to determine the incidence of post-operative recurrent pneumothorax within one-year timeframe after video-assisted thoracoscopic blebectomy/bullectomy…
- Trial name
- NCT06413966
- Testing
- Partially absorbable mesh, Apical pleurectomy
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Chiang Mai University
Pneumothorax
Pleural Abrasion Plus Minocycline Versus Apical Pleurectomy for Primary Spontaneous Pneumothorax
Optimal surgical management of primary spontaneous pneumothorax has been a matter of devate, especially regarding the method of pleurodesis.
- Trial name
- NCT00270751
- Testing
- 1 apical pleurectomy, 2 pleural abrasion + minocycline pleurodesis
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Analgesia, Postoperative Pain
Ultrasound-Guided Serratus Anterior Plane Block in Pneumothorax Surgery
A prospective randomized controlled study was undertaken to compare the postoperative analgesic effect between ultrasound-guided serratus anterior plane block and intercostal nerve block after single port video-assisted…
- Conditions
- Analgesia, Postoperative Pain, Pneumothorax
- Trial name
- NCT04191850
- Testing
- Single Port Video-Assisted Thoracoscopic Surgery
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Kyungpook National University Hospital
Primary Spontaneous Pneumothorax, Quality of Life
Impact of Ambulatory Management for Primary Spontaneous Pneumothorax in the Emergency Department on Quality of Life
Outpatient treatment of Primary Spontaneous Pneumothorax (PSP) compared to usual inpatient management could improve quality of care and represent a more efficient, generalizable and sustainable strategy.
- Conditions
- Primary Spontaneous Pneumothorax, Quality of Life, Ambulatory Care, Chest Tube
- Trial name
- EFFI-PNO (NCT06471608)
- Testing
- Ambulatory management, Standard Care
- Where
- 7 sites in France
- Volunteers
- 386 people
- Sponsor
- University Hospital, Strasbourg, France
Primary Spontaneous Pneumothorax
Early Chest Tube Removal After Surgery for Primary Spontaneous Pneumothorax: A Randomized Controlled Trial
Video-assisted thoracoscopic surgery (VATS) with blebectomy/wedge resection plus pleurodesis is the standard of care for recurrent primary spontaneous pneumothorax (PSP) or, in certain instances, after the first episode.
- Trial name
- NCT06411431
- Testing
- Early Chest Tube Removal, Standard Chest Tube Removal, Apical Chest Tube
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Swedish Medical Center