Clinical trials: Priming
Expectations, Motor Learning
Priming Expectations and Motor Learning With tDCS
The purpose of this study is to test if priming expectations of transcranial Direct Current Stimulation (tDCS) can improve the efficacy of tDCS in enhancing motor learning.
- Trial name
- NCT06039605
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Cardiovascular Diseases (CVD), Cerebro Vascular Disease
Identifying Risk Factors and Predicting Future Health Outcomes for Korean Patients With Heart and Blood Vessel Diseases: A Long-term Follow-up Study
This study aims to establish a comprehensive, long-term clinical registry infrastructure for heart and brain vascular diseases (cardiovascular diseases and stroke) at Samsung Medical Center.
- Trial name
- NCT07393412
- Testing
- Standard Medical Therapy, Revascularization Procedures, Lifestyle Modification
- Where
- South Korea
- Volunteers
- 800,000 people
- Sponsor
- Samsung Medical Center
Coronary Heart Disease
ORSIRO Stents Versus Xience PRIME Stents Assessed by Optical Coherence Tomography
This prospective, randomized trial will compare the extent of covered stent strut segments by assessed by Optical Coherence Tomography (OCT) of the ORSIRO DES with that of the XIENCE PRIME DES, which is the standard of choice of…
- Trial name
- ORSIRO_OCT (NCT01594736)
- Testing
- ORSIRO, XIENCE PRIME DES
- Where
- 2 sites in Germany
- Volunteers
- 30 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Colorectal Neoplasms, Microsatellite Instability
Pembrolizumab in MMR-Proficient Metastatic Colorectal Cancer Pharmacologically Primed to Trigger Hypermutation Status
In this study, MMRd metastatic colorectal cancer (mCRC) patients who failed standard therapies will undergo treatment with pembrolizumab, while RAS-extended mutated MMR-proficient mCRC patients will be tested for…
- Trial name
- ARETHUSA (NCT03519412)
- Testing
- temozolomide (induction),, pembrolizumab (treatment)
- Where
- 4 sites in Italy
- Volunteers
- 107 people
- Sponsor
- IFOM ETS - The AIRC Institute of Molecular Oncology
Depression
Priming Attachment Security Within an IAPT Setting
There is growing evidence that priming attachment security is associated with improved attitudes towards therapy, increased engagement and decreased levels of depression and anxiety.
- Trial name
- NCT04022759
- Testing
- Treatment as Usual with Security Prime, Treatment as Usual (Behavioural Activation)
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Long COVID, Pain
Pain Relief With Integrative Medicine (PRIMe)?: Feasibility of Acupuncture for Long COVID
The goal of this preliminary study is to test methods and procedures to be used in a fully-powered trial to evaluate acupuncture treatment effectiveness.
- Trial name
- NCT06476496
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pain, Disability
Additional Effects of Pain Neuroscience Education With Standard Pre-operative Physiotherapy on Post-laminectomy Pain and Disability.
This randomized controlled trial investigates whether adding Pain Neuroscience Education (PNE) to standard pre-operative physiotherapy improves outcomes after lumbar laminectomy.
- Conditions
- Pain, Disability, Laminectomy, Physical Therapy
- Trial name
- NCT07801586
- Testing
- Experimental Group - Pain Neuroscience Education + Standard Pre-operative Protocol, Control Group - Standard Pre-Operative Care
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Foundation University Islamabad
Atopic Asthma
Kinetics of IgE Memory B Cells, Plasmablasts and Plasma Cells After Whole Lung Allergen Challenge in Mild Asthmatics
The purpose of this study is to characterize the time course of B cell activation after allergen challenge, and more specifically measure the M1 prime related biomarkers.
- Trial name
- NCT01420003
- Testing
- Bone Marrow Aspiration, Tonsil Biopsy
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Hamilton Health Sciences Corporation
Haemophilus Influenzae Type b, Neisseria Meningitidis
Safety, Reactogenicity & Immunogenicity Study to Evaluate a Booster Dose of GSK Biologicals' Hib-MenC Given With Priorix™ in Toddlers (13-14 m) Primed With 3 Doses of Hib and MenC-CRM197
The purpose of this study is to evaluate the safety, reactogenicity and immunogenicity of a booster dose of the candidate Hib-MenC conjugate vaccine given concomitantly with measles, mumps and rubella (MMR) vaccine, versus…
- Trial name
- NCT00263653
- Testing
- Haemophilus influenzae type b- and meningococcal (vaccine)
- Where
- 16 sites in Spain
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Avian Influenza
Evaluation of Priming Effects by PLAI Vaccine on the Subsequent Response to Inactivated H5N1 Vaccine
This study aim to compare immunogenicity of the inactivated H5 influenza vaccine single dose between subjects previously vaccinated with LAIV H5N2 and naïve subjects
- Trial name
- NCT02229357
- Testing
- OrniFlu® inactivated vaccine
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Malaria, Falciparum, Malaria
Safety and Immunogenicity Study of the Malaria Vaccines FP9 PP and MVA PP
This study examines two new malaria vaccines (FP9-PP and MVA-PP) in healthy human volunteers to determine their safety and ability to induce a measurable immune response against malaria.
- Trial name
- NCT00374998
- Testing
- FP9-PP (FP9 polyprotein), MVA-PP (Modified Virus Ankara polyprotein)
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- European Vaccine Initiative
Stroke
Primed vs. Unprimed rTMS in Chronic Stroke
The goal of stroke rehabilitation is to restore function to the weak side of the body. However, this is often a difficult task to accomplish due to not only to damage from the stroke, but from increased excitability in the…
- Trial name
- NCT01757821
- Testing
- real 6-Hz primed low-frequency rTMS, real 1-Hz rTMS only
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Minnesota
AIDS Vaccines, HIV Infections
Phase 1 Safety Study of Two Experimental HIV Vaccines
This study will test whether two experimental HIV vaccines are safe and whether they cause any side effects in healthy adults. It will examine the body s immune response to the vaccines and monitor the social impact, if any, of…
- Conditions
- AIDS Vaccines, HIV Infections, HIV-1
- Trial name
- NCT00479999
- Testing
- VRC-HIVADV027-00-VP, VRC-HIVADV038-00-VP
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Labor Onset and Length Abnormalities
Effect of Tafoxiparin on Cervical Ripening and Induction of Labor in Term Pregnant Women With an Unripe Cervix
The study is designed as a randomized, Double-Blind, Placebo-Controlled, Parallel-Group Proof of Concept Study (section A) with a conditional dose finding follow up (Section B) to Evaluate the Efficacy on Cervical ripening…
- Trial name
- NCT04000438
- Testing
- DF01, PL1
- Where
- 7 sites in Finland, Sweden
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- Dilafor AB
Fluid Overload and Hypertension in Hemodialysis Patients
Effect of Sodium Concentration of Priming and Rinsing Fluids on Weight Gain
Sodium loading during hemodialysis treatment is common and may contribute to increased interdialytic weight gain and hypertension.
- Trial name
- NCT01168947
- Testing
- 5% dextrose solution
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Renal Research Institute
Recurrent Non-Small Cell Lung Carcinoma, Stage IIIA Non-Small Cell Lung Cancer
Azacitidine and Entinostat Before Chemotherapy in Treating Patients With Advanced Non-small Cell Lung Cancer
This randomized phase II trial studies how well azacitidine and entinostat before chemotherapy works in treating patients with non-small cell lung cancer that has spread to other places in the body.
- Conditions
- Recurrent Non-Small Cell Lung Carcinoma, Stage IIIA Non-Small Cell Lung Cancer, Stage IIIB Non-Small Cell Lung Cancer, Stage IV Non-Small Cell Lung Cancer
- Trial name
- NCT01935947
- Testing
- Azacitidine, Docetaxel, Entinostat
- Where
- 5 sites in United States
- Volunteers
- 17 people
- Sponsor
- National Cancer Institute (NCI)
Healthy
A Safety and Immunogenicity Study of Heterologous Prime-Boost Ebola Vaccine Regimens in Healthy Participants
The purpose of this study is to test the safety and immunogenicity of MVA-BN-Filo and Ad26.ZEBOV as heterologous prime-boost vaccine regimens in healthy adult participants.
- Trial name
- NCT02313077
- Testing
- MVA-BN-filo, Ad26. ZEBOV
- Where
- United Kingdom
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Crucell Holland BV
Aphasia
Sentence Production Training in Aphasia
This project focuses on developing a novel treatment for sentence production and comprehension in aphasia, using implicit priming.
- Trial name
- NCT05415501
- Testing
- Sentence training
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Purdue University
Influenza, Human
Vaccine for Prevention of Bird Flu
Study Design: This is a Phase I, randomized, open-label study to evaluate the safety, tolerability, and immunogenicity of four vaccination regimens against the influenza virus hemagglutinin H5.
- Trial name
- NCT00776711
- Testing
- Monovalent Influenza Subunit Virion (H5N1) Vaccine, A/Indonesia/05/2005, VRC-AViDNA036-00-VP
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy
Primed vs Unprimed Facilitatory and Depressive Paired Associative Stimulation
Following brain injury (e.g. stroke), application of non-invasive brain stimulation may improve rehabilitative efforts. However, the most effective method of non-invasive brain stimulation is unknown.
- Trial name
- NCT02619643
- Testing
- Transcranial Magnetic Stimulation (Magstim)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Minnesota