Clinical trials: Probiotic
Colonization, Asymptomatic, Colonisation
Encapsulated Probiotics & Gut Microbiota
The aim of this study is to determine whether encapsulation of probiotic bacteria using natural plant protein can enhance bacterial colonisation.
- Trial name
- Probiotics (NCT07439978)
- Testing
- probiotic containing L.rhamnosus R0011 strain, 200 ml yogurt drink
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Healthy, Hyperuricemia, Gout
Acute Effects of a Urate-lowering Bacterial Therapeutic on Small Intestinal Transcriptomics and Glycomics in Healthy Subjects
This is a pilot study investigating how a novel probiotic supplement (BEO001), with and without a dietary fiber (beta-glucan), affects the lining of the small intestine in healthy people.
- Trial name
- Bugs4U-MoA (NCT07366749)
- Testing
- BEO001 Probiotic, BEO001 Probiotic + Beta-Glucan
- Where
- Sweden
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Acne Vulgaris
Studying the Skin Microbiome and the Potential of a Topical Probiotic Cream for Patients With Acne
In this study the topical use of cream with live probiotic bacteria was evaluated for its efficacy in reducing acne symptoms and its effect on the skin microbiota on patients with acne.
- Trial name
- NCT03469076
- Testing
- YUN ACN Cream
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Con, Cons ti
Probiotic for Alleviating Functional Constipation in Adults
To investigate the clinical effects of probiotics in relieving chronic constipation in adults, and evaluate the improvement of symptoms in patients with constipation as well as their impacts on gastrointestinal function and gut…
- Conditions
- Con, Cons ti, Con s ti
- Trial name
- NCT07649564
- Testing
- Probiotic
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Healthy
A Study Investigating the Effect of Floradapt Mature Immune Defense on Nutrient Uptake and Digestive Health in a Healthy Elderly Population
This trial will be investigating the effect for Floradapt Mature Immune Defense on nutrient uptake and digestive health in a healthy elderly population.
- Trial name
- NCT04147923
- Testing
- Floradapt Mature Immune Defense + Multivitamin
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kaneka Americas Holding Inc.
Functional Gastrointestinal Disorders, Infant Conditions
Prevalence of FGIDs and Probiotics Study
This is a study to evaluate the prevalence of FGIDs in infants using the Thai version of Rome IV diagnostic questionnaire for functional gastrointestinal disorders in infants and evaluate the efficacy of Limosilactobacillus…
- Trial name
- PROOF (NCT06309199)
- Testing
- Biogaia
- Where
- Thailand
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Sarcopenia, Elderly
Omega 3, Leucine, Probiotic Lactobacillus Paracasei PS23 on Muscle Mass in Sarcopenic Subjects
The purpose of the study is to evaluate the effect of supplementation with a nutritional blend based on Omega 3 fatty acids, the probiotic leucine Lactobacillus paracasei PS23 (OLEP), on muscle mass recovery in sarcopenic…
- Conditions
- Sarcopenia, Elderly, Omega 3
- Trial name
- NCT04702087
- Testing
- OLEP
- Where
- Italy
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Periodontal Diseases
The Role of Probiotics in Periodontal Disease
In this randomized controlled trial, it was aimed to evaluate the effect of probiotics (chewable tablets) and kefir consumption in the initial periodontal treatment of periodontitis patients on the change of oral microbiota and…
- Trial name
- tropipd (NCT05211219)
- Testing
- Probiotics, AOÇ Kefir, Food without additional food supplements
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Gazi University
Dental Caries
Probiotics That Moderate pH and Antagonize Pathogens to Promote Oral Health
This study will examine the mechanisms of action of probiotics and synbiotics for control of oral diseases, with a particular focus on exploring new strategies for caries prevention and treatment.
- Trial name
- NCT02999230
- Testing
- Caries Free 1.5% Arginine, Caries Active 1.5% Arginine
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Florida
Healthy Adults
Prospective Tolerability Assessment of a Probiotic Dietary Supplement
The dietary supplement being investigated is a formula containing a combination of eight probiotic strains. The combination formula was developed to support general gastrointestinal and immune health.
- Trial name
- NCT04044144
- Testing
- Probiotic Dietary Supplement
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Metagenics, Inc.
Immunity
Investigation of A Children's Beverage Containing Different Probiotics
Investigating different bioactive ingredients in children's beverages and the effect on blood serum markers.
- Trial name
- NCT00990002
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Metabolic Syndrome
Obesity - Inflammation - Metabolic Disease: Effect of Lactobacillus Casei Shirota
Obesity and metabolic syndrome are linked by inflammation. Gut flora seems to play an important role in the development of inflammation and metabolic syndrome in obesity.
- Trial name
- NCT01182844
- Testing
- Lactobacillus casei Shirota
- Where
- Austria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vanessa Stadlbauer-Koellner, MD
Days Absent From Daycare, Respiratory Tract Infections
Effect of Probiotics in Reducing Infections and Allergies in Young Children Starting Daycare
The aim of the intervention is to examine the effect of a combination of the two bacterial strains BB-12 and LGG, provided for 6 month, on the prevalence of infections and allergic manifestations in small children, and how a…
- Conditions
- Days Absent From Daycare, Respiratory Tract Infections, Gastrointestinal Infections, Allergy
- Trial name
- ProbiComp (NCT02180581)
- Testing
- Probiotic (2 * 10^9 cfu/day)
- Where
- Denmark
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Focus on Healthy Infant Growth.
Infant Formula Supplemented With Probiotic Microorganisms and/or Prebiotic.
Evaluation the nutritional suitability of a based milk infant formula supplemented with friendly bacteria (probiotic microorganisms) and or nutritional fibers (prebiotic) to healthy, full term infants compare with an otherwise…
- Trial name
- NCT00836771
- Testing
- Infant Formula
- Where
- Israel
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Materna Laboratories
Gastro-intestinal Symptoms in Healthy Subjects
Effect of B.Lactis Consumption on Gastro-Intestinal (GI) Symptoms in Healthy Women Reporting Minor GI Symptoms
The purpose of this study is to assess the effect of a 28-day B.lactis consumption twice daily on Gastro-Intestinal (GI) symptoms in healthy women reporting minor GI symptoms.
- Trial name
- NCT05416151
- Testing
- Freeze-dried biotic, Maltodextrin
- Where
- France
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Group B Streptococcus Carrier in Childbirth, Gastrointestinal Symptoms
The Efficacy of Probiotics to Reduce Antepartum Group B Streptococcus Colonization.
This study is a randomized double blind, placebo controlled trial to determine the efficacy of an oral probiotic in reducing antenatal Group B Streptococcus colonization.
- Trial name
- NCT03696953
- Testing
- Florajen3
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Marquette University
Physiological Stress, Cognition - Other
Effects of Probiotics on Cognition and Health
This research intervention aims to examine the effects of a fermented dairy beverage on changes in behavioral and biological measures of cognition and stress among adults.
- Trial name
- EPOCH (NCT02849275)
- Testing
- Lactose Free 1% Milk, Probiotic Treatment
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Healthy
A Study of a Probiotic Food Supplement Containing B. Infantis (EVC001) in Healthy Breastfed Infants at Risk of Developing Atopic Dermatitis
The purpose of this study is to assess the effect of B. infantis (EVC001) versus placebo supplementation, in healthy breastfed infants at risk of developing atopic dermatitis (AD), on cumulative incidence of physician-diagnosed…
- Trial name
- NCT04662619
- Testing
- B. infantis
- Where
- Finland
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Dental Caries
Preventive Effect of a Probiotic Tablet on Oral Health in Preschool Children
The aim of the prospective project is to investigate effect of daily probiotic supplements on dental caries development in preschool children living in a low socioeconomic immigrant area in souithern Sweden.
- Trial name
- NCT01720771
- Testing
- probiotic tablet, sugar pill
- Where
- Sweden
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Gastrointestinal Health, Respiratory Health
Clinical Study to Evaluate the Safety and Efficacy of New Probiotic Strains in Health Adults
This trial is to determine the safety of 4 new probiotic strains and to assess their efficacy in reducing the incidence and/or duration of gastrointestinal problems and infections as well as respiratory infections in healthy…
- Conditions
- Gastrointestinal Health, Respiratory Health, Safety
- Trial name
- NCT04758845
- Testing
- Cocktail, CGI314, CSI08
- Where
- Slovenia
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Deerland Enzymes