Clinical trials: Probiotic
Environmental Exposure, PFAS Exposure
Effect of a Dietary Supplement Versus Placebo on Serum PFAS Levels in Male Firefighters
This study is designed to evaluate the effect of a probiotic dietary supplement containing Streptococcus salivarius on serum PFAS levels in male firefighters with documented occupational PFAS exposure, following twice-daily use…
- Trial name
- AFCRO202 (NCT07846371)
- Testing
- Streptococcus salivarius 46-SL1
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cambiotics ApS
Intestinal Flora
A Probiotic That Improve Intestinal Flora
Purpose: to verify the physiological properties of Lactobacillus rhamnosus LRa05. Bacterial count:100 billion Test Objective: to test and collect the changes of intestinal flora before and after the daily use of LRa05 product.
- Trial name
- NCT06103240
- Testing
- Lacticaseibacillus rhamnosus LRa05
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Acne Vulgaris
Oral Probiotics on the Microbiome and Lipidome in Acne Vulgaris
The purpose of this study is to determine how probiotics affect sebum production and gut health in those with acne vulgaris.
- Trial name
- NCT04596748
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Healthy
Safety and Efficacy of Probiotics in Bangladeshi Infants
Here the investigators propose to preliminarily investigate the safety and effects of probiotics in infants in Bangladesh through a pilot randomized clinical trial.
- Trial name
- NCT01899378
- Testing
- Lactobacillus reuteri DSM 17938, Bifidobacterium longum infantis
- Where
- Bangladesh
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Stanford University
Endometriosis, Bacterial Vaginosis
Effects of a Multi-strain Oral Probiotic on the Vaginal Microbiota Composition in Healthy Women and Women with Endometriosis
Endometriosis is a chronic inflammatory disease affecting approximately 10-15% of reproductive age women, and, in recent years, an association between this pathology and dysbiosis, either involving the gut or the genital…
- Conditions
- Endometriosis, Bacterial Vaginosis, Healthy Volunteer
- Trial name
- NCT06592976
- Testing
- Multi-strain Oral Probiotic (CDS22-formula)
- Where
- Italy
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Obesity, Intra-Abdominal Fat
Effect of a Probiotic on Visceral Fat Accumulation
The study's main objective is to investigate if an extract containing the probiotic Bifidobacterium animalis subsp. lactis BPL1 (CECT 8145) has a positive effect on the accumulation of abdominal visceral fat in people with…
- Conditions
- Obesity, Intra-Abdominal Fat, Subcutaneous Fat, Abdominal
- Trial name
- BIFFAT (NCT02921217)
- Testing
- Active Probiotic, Inactivated probiotic, Control
- Where
- Spain
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Biopolis S.L.
Gut Microbiota, Adiposity
Effect of a Synbiotic on the Gut Microbiota and Adiposity-related Markers in Healthy Overweight Subjects
The purpose of this study is to investigate the effects of a synbiotic (ProSynbiotic) on the gut microbiota composition, body composition and adiposity-related genes and metabolic markers in healthy overweight adult subjects.
- Trial name
- NCT02151825
- Testing
- Synbiotic
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Texas State University, San Marcos
Healthy 70 Street Market Vendors Working in Highly-polluted Areas of Turin
Biotics Intervention Oriented to Rescue From Environmental Pollution Inflammatory Responses
Improving air quality in urban areas represents a major public health challenge. In regions such as the Po Valley, airborne particulate matter (PM₁₀ and PM₂.₅) concentrations frequently exceed World Health Organization limits…
- Trial name
- BIOREPAIR (NCT07418489)
- Testing
- pro-postbiotic
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Overweight (BMI > 25), Obese, Otherwise Healthy Volunteers
L. Acidophilus (Strain TW01) on Gut Health, Body Composition, and Inflammation
This is a pilot research study to investigate the effects of a probiotic supplement (L. acidophilus, strain TW01) on substances found in the stool and bloodstream, gut bacteria composition, body composition, as well as any…
- Trial name
- NCT06912100
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Gastrointestinal Discomfort
Safety and Efficacy of a Probiotic Supplement
Exercise-induced gastrointestinal dysfunction is common amongst endurance athletes and is characterized by gastrointestinal permeability, also known as "leaky gut." Probiotics have been shown to improve gut permeability through…
- Trial name
- NCT05425329
- Testing
- I3.1
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Children, Only
Ingestion Effect of Formula Milk With Triple Bifidobacteria Strains on Fecal Quality and Metabolites in Healthy Children
The goal of this clinical trial is to compare healthy children between 1 to 3 years old. The main question it aims to answer is 1.
- Trial name
- NCT06044376
- Testing
- Formula milk with triple Bifidobacterium probiotic strain, Formula milk
- Where
- 10 sites in Indonesia
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Healthy, Diarrhea
Calcium, Probiotics and Acute Diarrheal Disease Among Indonesian Children
This is a long term study on the efficacy of dietary calcium with or without probiotic strains in reducing the mean number of episodes and duration of diarrheal disease.
- Trial name
- NCT00512824
- Testing
- low calcium milk of 180 ml, regular milk of 180 ml, regular milk of 180 ml + probiotics
- Where
- Indonesia
- Volunteers
- 494 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Obesity, Hyperglycemia
The Effect of a Bifidobacterium and Polydextrose on Body Fat Mass
Obesity is a major problem worldwide, and it is related to abnormalities in glucose and lipid metabolism. The purpose of this study is to investigate the effect of a dietary supplement containing probiotic (Bifidobacterium…
- Conditions
- Obesity, Hyperglycemia, Insulin Resistance
- Trial name
- MetSProb (NCT01978691)
- Testing
- Bifidobacterium animalis ssp. lactis 420, Polydextrose
- Where
- 4 sites in Finland
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Danisco
Vaginal Health
Effects of Oral Probiotic Product on Vaginal Microbial Community and Parameters of Vaginal Health
The purpose of the study is to assess the efficacy and safety of an oral probiotic product on the vaginal microbiome and on parameters of vaginal health.
- Trial name
- NCT03543982
- Testing
- Oral probiotic product
- Where
- Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- UAS Labs LLC
Healthy
Infant Microbiota and Probiotic Intake Study
The purpose of this study is to determine if supplementing healthy term infants delivered by C-section or vaginal delivery who only consume breastmilk with a probiotic for 21 consecutive days increases levels of bacteria in…
- Trial name
- IMPRINT (NCT02457338)
- Testing
- Bifidobacterium
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Intestinal Health
Research on the Improvement of Intestinal and Immune Functions by Probiotics
Evaluate the effectiveness and safety of Limosilactobacillus fermentum LF61 as a food supplement compared to a placebo in improving intestinal and immune functions in healthy adults.
- Trial name
- NCT06873425
- Testing
- Probiotic
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Pregnancy, Lactation
The Role of Human Milk in Development of Breast Fed Child's Intestinal Microbiota
The ideal food for normal infants is human milk. In addition, breast milk has been shown to be a continuous source of commensal, and⁄or probiotic bacteria to the infant gut where they play a key role in the initiation and…
- Trial name
- MYMILK (NCT01548313)
- Where
- Slovenia
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Safety, Tolerability
Evaluation of Safety and Human Tolerance of Oral Probiotic Streptococcus Salivarius eK12
The human oral cavity contains a diverse community of microorganisms essential for oral and overall health. Streptococcus salivarius K12 (eK12) has emerged as a promising oral probiotic due to its natural colonization of the…
- Trial name
- NCT06380270
- Testing
- Oral probiotic Streptococcus salivarius eK12
- Where
- Pakistan
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
Gut Microbiota Modulation
The Role of Probiotic LH76 in Human Gut Health
This study aims to evaluate the safety and efficacy of the probiotic LH76 as a dietary supplement in healthy adults. The research will assess its effects on gut microbiota composition, intestinal health, and immune function…
- Trial name
- NCT06875375
- Testing
- probiotic LH76
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Influenza
PRIMAGE (Probiotics, Immunity and Ageing)
Ageing dramatically affects immune function; this phenomenon is known as immunosenescence and partly explains the increased susceptibility for infection in older individuals.
- Trial name
- PRIMAGE (NCT01066377)
- Testing
- Prebiotic and probiotic mix
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Reading
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