Clinical trials: Probiotic
Adults Aged 18-45 Years
The Safety and Efficacy of Probiotic for Improving Intestinal and Immune Function
To evaluate the safety and efficacy of Streptococcus salivarius subsp. thermophilus ST36 in healthy adults on immune function and intestinal health.
- Trial name
- NCT06779994
- Testing
- Probiotic
- Where
- China
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Rheumatoid Arthritis
Effects of Probiotics on Rheumatoid Arthritis Patients
The purpose of the present study is to examine the utility of probiotics as an adjunctive therapy (in addition to patients' pharmacotherapy) for the treatment of Rheumatoid Arthritis.
- Trial name
- NCT00664820
- Testing
- Probiotic capsules containing Lactobacillus rhamnosus GR-1 and L. reuteri RC-14
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
C-Section
Influence of Probiotics on Early Gut Microbial Colonization
The goal of this clinical trial is to learn whether daily probiotic drops plus vitamin D3 can improve early gut microbiome colonization in healthy infants born by C-section. It will also assess safety and tolerability.
- Trial name
- STORKIE (NCT07608341)
- Testing
- Probiotic drops
- Where
- 2 sites in Finland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- BioGaia AB
Influenza-like Illness
Probiotic and Influenza Vaccination to Reducing Influenza-like Illness Incident in Elderly
To asses the effect of the probiotic and influenza vaccination alone and combination on enhancing immune response to influenza-like illness (ILI) and reducing ILI incidence in the elderly
- Trial name
- NCT03695432
- Testing
- Flubio, Lacidofil
- Where
- Indonesia
- Volunteers
- 910 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Gingival Inflammation
Evaluation of The Effect of Live Probiotic Cultures Present in Fermented Dairy Product (Yogurt) Versus The Effect of Freeze-Dried Probiotic Sachets on Gingival Bleeding of Adolescents
To evaluate the effect of probiotics supplied in two different forms (dairy products containing probiotics as yogurt and freeze-dried synthetic probiotics sachets) on improving gingival condition and caries potentiality of dental…
- Trial name
- NCT03640065
- Testing
- freeze-dried probiotic sachets, fermented dairy product ( yogurt)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy
Probiotics on Stress-associated Gastrointestinal Function in University Students
The purpose of this research study is to evaluate the effect of a daily supplement of probiotics (Lactobacillus gasseri KS-13, Bifidobacterium bifidum G9-1, Bifidobacterium longum MM-2) on stress-associated gastrointestinal…
- Trial name
- SAS (NCT03056846)
- Testing
- Probiotic Combination, Bifidobacterium bifidum, Bifidobacterium longum
- Where
- United States
- Volunteers
- 634 people, healthy volunteers welcome
- Sponsor
- University of Florida
Blood Pressure
Effect of a Probiotic-based Product on Blood Pressure
The aim of the present study was to examine the efficacy of a probiotic-based product on either reducing hypertension or preventing a high normal blood pressure from reaching hypertensive levels.
- Trial name
- NCT01989702
- Testing
- Fermented blueberry drink, Sachets with probiotic bacterial powder
- Where
- Sweden
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Probi AB
Mild Gastrointestinal Symptoms in Healthy Adults
BacterioPHAGE for Gastrointestinal Health 2 Study
The BacterioPHAGE for Gastrointestinal Health-2 study is designed to determine if a commercial bacteriophage product can increase the survival and efficacy of probiotic bacteria that will be concurrently administered.
- Trial name
- PHAGE2 (NCT04511221)
- Testing
- Bifidobacterium animals subsp. lactis BL04+PreforPro, Bifidobacterium animals subsp. lactis BL04
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Periodontal Disease
Study of Colonization of Strains L.Plantarum and L.Brevis in the Product AB-DENTALAC Chewing Gum
Study will follow a randomized, double-blind, placebo-controlled design with two groups in parallel,N of 40 patients in 6 weeks of follow up for the evaluation of two different posology models (daily consumption of probiotic gum…
- Trial name
- AB-GUM-2016 (NCT03540498)
- Testing
- AB-DENTALAC [Probiotics (study)]
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Helicobacter Pylori Infection
The Role of Probiotics in the Eradication of Helicobacter Pylori
All patients will receive quadruple eradication therapy for 10 days with Omerazole 20mg x2, Amoxicilin 1g x2, Clarithromycin 500mg x2 and Metronidazole 500mg x2. The patients will be randomised into two groups.
- Trial name
- NCT04178187
- Testing
- Caps Lactolevure
- Where
- 5 sites in Greece
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Evangelismos Hospital
Generally Healthy
Modulation of Gut Microbiota by Probiotic in Children
This project aims to study the benefits of probiotics namely Bifidobacterium infantis YLGB-1496 in modulating gut microbiota of healthy children, among pre-school children in Malaysia <7 years old.
- Trial name
- NCT06474234
- Testing
- Probiotic
- Where
- Malaysia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Min-Tze LIONG
Colic, Infantile
PRobiotics for EVEry Newborn Trial
The aim of the study is to compare prevention (oral supplementation with the probiotic L. reuteri administered to every newborn within the first week of life for 12 weeks) with treatment-as-needed (supplementation with the…
- Trial name
- PREVENT (NCT04537494)
- Testing
- L. reuteri
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Less Than 3 Months Old, Healthy Infants
An Intervention Study in Healthy Infants Aged 0-6 Months With Probiotics Lacticaseibacillus Rhamnosus LRa05 (LRa05) and Bifidobacterium Animalis Subsp. Lactis BLa80 (BLa80) vs. Placebo, for Promoting Gut Microbiome Development.
The probiotics Bifidobacterium animalis subsp. lactis BLa80 and Lacticaseibacillus rhamnosus LRa05 have potential to enhance infant health and development based on previous research conducted on human infants.
- Trial name
- SMILE (NCT07505329)
- Testing
- Probiotic
- Where
- Ireland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University College Cork
Healthy Elderly People
Potential Benefits of Dietary Advices Alone or Associated to Nutraceutical Food Supplements Argan Oil, VSL#3 Probiotic Blend, 5203-L Fruit Extract Terpene
Ageing of the population is a major event in the world. Gerontological/geriatric literature unanimously indicate that physical exercise and diet are at present the two available fundamental approaches to contrast/prevent most of…
- Trial name
- RISTOMED (NCT01069445)
- Testing
- VSL#3® probiotic blend, AISA-5203-L fruit extracted terpene, Argan oil
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Fatigue, Stress, Job
Effects of Probiotics on Gut Microbiota, Endocannabinoid and Immune Activation and Symptoms of Fatigue in Dancers
The aim of the planned research is to assess the dynamics of changes in the elements of the gut-brain axis (GBA), the cytokine profile and the endocannabinoid system markers, after dietary supplementation with probiotics…
- Trial name
- NCT05567653
- Testing
- Lactobacillus helveticus Rosell-52 and Bifidobacterium longum Rosell-175 (Sanprobi Stress)
- Where
- Poland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Healthy
Clinical Study to Assess the Effects of Prebiotic and Probiotic Supplement
Randomized, Crossover, Double-Blind, Placebo-Controlled, Single-Center Clinical Study with Daily Food Log, Stool Samples, Blood Draws, and Validated Questionnaires (GSRS, Bristol stool chart, and DQLQ) with Oral Dietary Supplement
- Trial name
- NCT06794619
- Testing
- Dietary Supplement with actives
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Olly, PBC
Anxiety, Stress
Evaluation of a Probiotic On Anxiety and Stress in Healthy Adults Sensible to Daily Stress
The purpose of the the study is to determine if PROBIOSTICK® decrease stress and anxiety of people sensible to daily stress.
- Trial name
- BIOSTRESS (NCT00807157)
- Testing
- PROBIOSTICK® during 30 days
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Institut Rosell Lallemand
Constipation
Probiotics for Alleviating Chronic Constipation in Adults
To investigate the clinical effects of probiotics in relieving intestinal motility and chronic constipation through regulating gut microbiota.
- Trial name
- NCT07152795
- Testing
- Probiotic
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Obesity
Research on Probiotics in Improving Obesity
Assess the effects of Akkermansia muciniphila Akk11 heat - killed bacteria capsules compared to a placebo on body composition indicators (weight, BMI, body fat rate, waist - hip ratio (WC), wrist circumference, visceral fat area…
- Trial name
- NCT06964919
- Testing
- Probiotic
- Where
- China
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Health of the Human Microbiome
Dogs as Probiotics
Studies show that family members share as much or more of the composition of their microbiota (the trillions of micro-organisms in our guts) with their dogs as they do with each other (Song et. al. 2013).
- Trial name
- NCT02343731
- Testing
- Introduction of a dog into the home
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Arizona
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