Clinical trials: Probiotic
Microbiota, Constipation
A Probiotic Blend Reduces Gastrointestinal Symptoms and Positively Impacts Microbiota Modulation in a Randomized Study
This randomized, placebo-controlled, double-blind study will determine the effect of daily supplementation with a probiotic blend in 60 apparently healthy men and women recruited at a single investigational center in Northeast…
- Conditions
- Microbiota, Constipation, Candida
- Trial name
- NCT05614726
- Testing
- 575mg [30 billion colony forming units] probiotic blend of Bifidobacterium breve, Lactobacillus acidophilus, Lacticaseibacillus rhamnosus, Saccharomyces boulardii, and alpha amylase
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- The Center for Applied Health Sciences, LLC
Adverse Effects, Healthy
Effect of Probiotic Intake in Healthy Population
The main objective of this project is to evaluate the absence of adverse gastrointestinal effects following the consumption of a daily probiotic capsule during 15 days.
- Trial name
- PROBIO (NCT07165457)
- Testing
- Probiotic group
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Healthy
Study of the Effects of a New Infant Formula Supplemented With a Probiotic Over the Corporal Composition of Infants
This is a multicentric, randomized, blinded, controlled trial to study the effects of a new infant formula on the changes in the newborn body composition over time: weight gain, anthropometric data, incidence of infections…
- Trial name
- NCT05303077
- Testing
- Nutribén Innova® 1, Nutribén®, Breastfeed
- Where
- 21 sites in Spain
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Alter Farmacia, S.A.
Intestinal Permeability, Challenge Test
Intestinal Barrier Function and Probiotics.
Rationale: Enterotoxigenic Escherichia coli (ETEC) bacteria adhere to the mucosa of the proximal intestines. There it produces an toxin which presents a local and relevant challenge to the intestines.
- Conditions
- Intestinal Permeability, Challenge Test, Intestinal Health, Inflammation
- Trial name
- NCT01241201
- Testing
- Priobiotic supplement VSL#3
- Where
- Netherlands
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- TNO
Gastrointestinal Disorder, Immunologic Diseases in Children
Whole Grain, Gluten-containing Cereal and PROBIOtics to Evaluate Digestive TOLERAance and Immuno-inflammatory Response
This study will assess the development of gastrointestinal health in terms of digestive tolerability and immune-inflammatory response at the intestinal level comparing a conventional gluten-free cereal with a new cereal with…
- Trial name
- PROBIOTOLERA (NCT04021303)
- Testing
- Experimental cereal, Conventional cereal
- Where
- Spain
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Laboratorios Ordesa
Moderate Hypercholesterolemia
A Trial to Evaluate the Efficacy of AB-Life Probiotic Product on LDL-Cholesterol Reduction in Moderate Hypercholesterolemia
This study aims to demonstrate the effect of the chronic consumption of AB-Life probiotic blend on blood LDL cholesterol level in volunteers with moderate hypercholesterolemia.
- Trial name
- NCT02198703
- Testing
- Probiotics bacterial strains
- Where
- 2 sites in France
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Celiac Disease
Efficacy of Cholesterol-lowering L. Plantarum on Cardiometabolic Health Biomarkers in Coeliac Disease Patients
Recent studies have also shown that 30% of the world's population carries the susceptibility genes for coeliac disease and that only 2-5% of these individuals are really affected, however, studies suggest the existence of other…
- Trial name
- ProCoChoL (NCT06178107)
- Testing
- LP-LDL Probiotic
- Where
- 2 sites in Italy, United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Roehampton
Metabolism
Impact of Probiotics on Drug, Vitamin, and Hormone Metabolism
This is an open-label, fixed sequence study of the effect of probiotics supplementation on drug, vitamin, and hormone metabolism.
- Trial name
- NCT04281407
- Testing
- Visbiome
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Washington
Occasional Constipation
A Study Investigating the Effect of Digesta-Lac in Healthy Adults With Occasional Constipation
This investigation will evaluate the effect of Digesta-Lac in adults with occasional constipation in a single-center, randomized, double-blind, placebo-controlled, parallel group 2-arm study for 3 weeks.
- Trial name
- NCT02423564
- Testing
- Digesta Lac
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- KGK Science Inc.
Acne Vulgaris, Hydration Acne
The Impact of Probiotics on Skin Hydration in Youth with Mild Acne
The goal of this clinical trials is to test the impact of probiotics on skin hydration in adolescents and young adults with mild acne.
- Trial name
- YSH (NCT05755256)
- Testing
- Probiotic
- Where
- France
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Denture Stomatitis, Dentures
Oral Probiotics and Denture Care in Saudi Arabia: Evaluating Knowledge, Practices, and the Future of Innovative Hygiene Solutions
The goal of this observational study is to learn about denture wearers' knowledge, awareness, and self-reported practices regarding denture hygiene and oral probiotics, and to assess whether these are associated with clinical…
- Conditions
- Denture Stomatitis, Dentures, Halitosis, Biofilms
- Trial name
- NCT07475195
- Testing
- This is a cross-sectional observational study. Participants are not assigned to any treatment or preventive intervention.
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Saud University
Diarrhoea, Respiratory Diseases
The Effect of Probiotics on Infections in Toddlers
Probiotics has been known as a dietary supplement for a long period. Recent clinical trials indicate that probiotics might have an effect in preventing common infection diseases in children.
- Trial name
- NCT00823056
- Testing
- probiotics
- Where
- Denmark
- Volunteers
- 454 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Aging
Probiotic on Psychological and Cognitive Effects
This study will determine whether supplementation of probiotic Lactobacillus Rhamnosus GG improves psychological status in middle age and older adults through a 12-week, randomized, double-blind, placebo-controlled clinical…
- Trial name
- NCT03080818
- Testing
- Probiotic - Lactobacillus Rhamnosus GG
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kent State University
Microbial Colonization
Effect of a Multi Strain Probiotic on the Gut Microbiota
Over recent years there has been a lot of research looking at how the bacteria in our gut affect our health. Changes to gut bacteria has been linked to several diseases.
- Trial name
- NCT04554641
- Testing
- Fasted breath samples, Daily Diary, Stool sample
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- The Functional Gut Clinic
Clostridium Difficile Infection Recurrence
Bacillus Velezensis DSM 33864 for Reduction of the Risk of Recurrent Clostridioides Difficile Infections
The purpose of this study is to determine whether a single strain capsulated probiotic, when used after standard C. difficile antibiotic therapy, is effective in reducing the risk of infection recurrence mediated by a decrease in…
- Trial name
- NCT05606159
- Testing
- Bacillus velezensis DSM 33864
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Novozymes A/S
Pregnancy
Lactobacillus Reuteri Feasibility Study on Probiotic Treatment and Perinatal Microbiome
Investigators want to investigate if the Lactobacillus Reuteri (probiotic bacteria) given to pregnant women can be found in different maternal compartments and in the first stool and oral swab collected immediately after birth of…
- Trial name
- NCT02693028
- Testing
- Probiotic lozenges, Probiotic capsules, Probiotic chewing gum
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Vaginal Infection, ASC-US
Probiotic Implementation as Help in Solving Vaginal Infections
Over recent years, a growing interest has developed in microbiota and in the concept of maintaining a special balance between Lactobacillus and other bacteria species in order to promote women's well-being.
- Trial name
- NCT03372395
- Testing
- Lactobacillus rhamnosus BMX 54
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Caries
Acid Production in Dental Plaque After Exposure to Probiotic Bacteria
The increasing interest in probiotic lactobacilli in health maintenance has raised the question of potential risks. One possible side effect could be an increased acidogenicity in dental plaque.
- Trial name
- NCT01700712
- Testing
- Probiotic Lactobacilli reuteri
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Fatigue, Stress, Job
Effects of Probiotics on Gut Microbiota, Endocannabinoid and Immune Activation and Symptoms of Fatigue in Dancers
The aim of the planned research is to assess the dynamics of changes in the elements of the gut-brain axis (GBA), the cytokine profile and the endocannabinoid system markers, after dietary supplementation with probiotics…
- Trial name
- NCT05567653
- Testing
- Lactobacillus helveticus Rosell-52 and Bifidobacterium longum Rosell-175 (Sanprobi Stress)
- Where
- Poland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
VOLUNTEERS
Lactobacillus Plantarum 3547 Effects Over Inflammatory and Immunologic Markers
The purpose of this study is to evaluate the effects of the probiotic Lactobacillus plantarum 3547 over different inflammation and immune system markers on a healthy middle-aged group.
- Trial name
- NCT02622867
- Testing
- Lactobacillus plantarum 3547, Maltodextrin
- Where
- Spain
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
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