Clinical trials: Probiotic
Lactose Intolerance
Effect of B.Bifidum 900791 Intake in Adult With Hypolactasia and Lactose Intolerance
Lactase is high in the newborn intestine, allowing him to digest the high amounts of lactose present in breastmilk. From weaning, lactase is genetically programmed to decrease, reaching residual levels in the adult.
- Trial name
- NCT03952988
- Testing
- Probiotic ice cream
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chile
Childhood Obesity, Maternal Obesity During Childbirth
Prenatal Probiotic Intervention
This study will assess the feasibility of a randomized control trial in which the effects of probiotic supplementation throughout pregnancy on maternal insulin sensitivity and inflammation, as well offspring gene expression and…
- Conditions
- Childhood Obesity, Maternal Obesity During Childbirth, Insulin Resistance, Inflammation
- Trial name
- NCT03240419
- Testing
- Probiotics
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Stress, Attention Disturbances
Impact of Probiotic Supplementation on Cognition and Related Health Outcomes Among Video Gamers
The primary objective of the current study is to investigate the effect of two probiotic formulations on task-switching following acute stress in healthy, adult action video gamers.
- Trial name
- NCT05545813
- Testing
- Probiotic
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Healthy
Probiotics to Improve Women's Health
The purpose of the study is explore the effect of probiotics on plasma lipopolysaccharides (LPS) concentrations, as well as insulin and glucose levels, in obese women prior to and after dietary challenges (high carbohydrate meal…
- Trial name
- NCT01800760
- Testing
- Probiotics
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Survival of Probiotics During GI Transit, GI Symptoms
Acidophilus Pearls Fecal Recovery Study
Commercial probiotics can be delivered in numerous forms. The two most common delivery forms are similar to the two product formats to be tested.
- Trial name
- NCT02001610
- Testing
- Acidophilus pearls, Hard shell gelatin capsules
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Florida
Infantile Diarrhea
Prophylaxis of Gastrointestinal Infections With EcN
This interventional trial shall investigate the efficacy and tolerance of a suspension with non-pathogenic probiotic E. coli strain Nissle (EcN) on prophylaxis against gastrointestinal infections in newborn and infants.
- Trial name
- PIURA (NCT01469273)
- Testing
- Mutaflor® Suspension
- Where
- 3 sites in Peru
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Hospital San Bartolome
Preeclampsia, Preterm Birth
Pregnancy Complications - A Probiotic Interventional Study
Investigators hypothesize that a) probiotics decrease the overall inflammatory state in the pregnant woman, especially in women with high risk pregnancies.
- Trial name
- NCT02693041
- Testing
- probiotic
- Where
- Sweden
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Infant, Newborn, Immunity
The Bloom Infant Probiotic (BIP) Study
The goal of this clinical trial is to investigate whether administering a probiotic (Infloran®) to infants who received antibiotics in the first 28 days of life can restore or enhance their immune response to routine vaccines.
- Conditions
- Infant, Newborn, Immunity, Immunisation, Antibiotic Treatment
- Trial name
- BIP (NCT07189390)
- Testing
- Probiotic
- Where
- 2 sites in Australia
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- South Australian Health and Medical Research Institute
Heart Failure
Probiotics and Inflammatory Status in Patients With Heart Failure
Cachexia is a very common condition in patients with advanced heart failure (HF) and is considered a predictor of mortality. Studies have been carried out in an attempt to discover the mechanisms that leads to cachexia in order…
- Trial name
- PROBHF (NCT03968549)
- Testing
- Probiotic
- Where
- Brazil
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Healthy
Stress-buffering and Sleep Disturbance-resilient Effects of a Dual Bifidobacterium Longum Combination Under Short-term Travel
This study aims to evaluate the effects of a dual Bifidobacterium longum probiotic formulation (dipro-O and dipro-X) on sleep quality, stress responses, and gut microbiota stability in healthy adults during short-term travel.
- Trial name
- NCT07511855
- Testing
- Probiotic
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Min-Tze LIONG
Low Iron Stores
The Effect of Lactobacillus Cultures on Iron Bioavailability.
The purpose of this study is to determine the effect of a lactic acid fermented oat gruel on iron absorption in the upper and lower part of the intestine, respectively.
- Trial name
- NCT00283491
- Testing
- Active Lactobacillus plantarum 299v, Inactive Lactobacillus plantarum 299v
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Rectal Cancer, Gut Microbiomes
Autologous Probiotics in Patients With Defunctioning Ileostomy Following LAR for Rectal Cancer
Rectal cancer patients who received low anterior resection combined with ileostomy may effectively reduce the probability of anastomotic leakage after surgery.
- Conditions
- Rectal Cancer, Gut Microbiomes, Autologous Probiotic Transplantation, Defunctioning Ileostomy
- Trial name
- NCT07366047
- Testing
- Autologous Probiotics
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Peking University Cancer Hospital & Institute
Healthy, Stress-related Problem
The Effect of Probiotic Supplementation on Mental Health in Healthy Volunteers
Probiotics are "live microorganisms which when administered in adequate amounts confer a health benefit on the host". Accumulating evidence indicates their effect in mental health restoration.
- Conditions
- Healthy, Stress-related Problem, Depression, Anxiety
- Trial name
- ProBeMent (NCT06391216)
- Testing
- Lactobacillus helveticus R0052 and Bifidobacterium longum R0175
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Obesity, Homeostasis
Probiotic Intervention on Body Weight
This study is a randomized controlled trial with 120 overweight or obese (body-mass index, BMI, ≥ 24 kg/m²) participants and 20 normal-weight participants.
- Conditions
- Obesity, Homeostasis, Weight Loss, Probiotic Intervention
- Trial name
- NCT06989177
- Testing
- General lifestyle and nutritional education, Energy-restricted nutritional and lifestyle intervention, Probiotic
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Sciences
Upper Respiratory Tract Infection, Prevention
Clinical Trial to Evaluate the Efficacy of Lacticaseibacillus Rhamnosus CRL1505 in the Prevention of Upper Respiratory Tract Infections in Children
Randomized, double-blind, placebo-controlled, parallel-group, clinical trial to assess the efficacy of the intake of a probiotic product composed of Lacticaseibacillus rhamnosus CRL1505 strain in reducing or preventing upper…
- Trial name
- NCT07154992
- Testing
- Probiotic - Lacticaseibacillus rhamnosus CRL1505
- Where
- Spain
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Bioithas SL
Healthy, Constipation
Effect of a Fermented Milk Product With Probiotics Alone or in Combination With Fibers on Constipation Symptoms
First experimental study (Proof Of Concept) to investigate bowel function parameters on which a fermented milk product with probiotics alone or in association with fibers has a potential effect.
- Trial name
- NCT02461485
- Testing
- Fermented milk product containing Probiotics, Fermented Milk Product containing Probiotics + Fibers C, Fermented Milk Product containing Probiotics + Fibers W
- Where
- Ireland
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Pain
Efficacy of Yogurt Containing BB12 in Subjects With GI Symptoms
The purpose of this study is to determine if probiotics bacteria, specifically bifidobacterium lactis (BB12) improve gastrointestinal symptoms in subjects with functional gastrointestinal symptoms (i.e., non-patients…
- Trial name
- NCT00618488
- Testing
- Probiotic BB12 - Bifidobacterium lactis
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of North Carolina
Gingivitis
The Effect of Probiotics on Gums Health and Bad Breath
the study is about using healthy bacteria to improve the overall gingival and overall health and prevent or decrease the bad odor of the mouth caused by bad bacteria
- Trial name
- NCT06910397
- Testing
- Probiotic Arm
- Where
- Iraq
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Pregnancy, Obesity
Nutrition and Pregnancy Intervention Study
A randomized double-blind placebo controlled intervention study with pregnant obese women (n=440) will be conducted. The intervention will involve consumption of fish oil and/or probiotic capsules from early pregnancy until 6…
- Conditions
- Pregnancy, Obesity, Gestational Diabetes Mellitus, Adiposity
- Trial name
- NCT01922791
- Where
- 2 sites in Finland
- Volunteers
- 439 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Potential Abnormality of Glucose Tolerance, Appetite Disorders
Acute Effects of Juice Consumption With Biofunctional Compounds and Probiotics on Glucose Metabolism
This study investigated the short-term effects of fruit juice enriched with Vitamin D3 or n-3 PUFA or probiotics and the combination of the three ingredients on glucose metabolism.
- Trial name
- NCT05702359
- Testing
- Glucose as reference food, Control juice, Juice with vitamin D3
- Where
- Greece
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Agricultural University of Athens
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