Clinical trials: Probiotic Intervention
Gastroenteritis, Bacterial Infection
The Effect of Probiotics on E. Coli Gastroenteritis
Background: The incidence of gastrointestinal infections is very high. In European countries 10-25% of the population suffers from at least one foodborne infection per year.
- Conditions
- Gastroenteritis, Bacterial Infection, Diarrhea
- Trial name
- PRETEC (NCT01225042)
- Testing
- probiotics
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NIZO Food Research
ADHD, ASD
Nutritional Intervention for Children With ASD and/or ADHD
Based on alterations in the intestinal microbiota in children with ASD and the high comorbidity between ASD and ADHD, the aim of this project was to assess whether the administration of probiotics with strains related to the…
- Conditions
- ADHD, ASD, Probiotics, Microbiota
- Trial name
- PRONED (NCT05167110)
- Testing
- Probiotic
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Atopic Dermatitis
The Effect of a Probiotic Intervention in Healthy Subjects and Patients With Atopic Dermatitis
The study was performed to investigate the effects of a probiotic supplementation containing Lactobacillus paracasei Lpc-37, Lactobacillus acidophilus 74-2 and Bifidobacterium animalis subsp. lactis DGCC 420 (B.
- Trial name
- NCT00550472
- Testing
- probiotics
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Jena
Maternal Exposure, Health Behavior
Brain Probiotic and LC-PUFA Intervention for Optimum Early Life
Probiotics is suggested to play several roles in promoting health, including alleviating disease symptoms, protection against atopic disease, and modulating the immune system by improving the beneficial gut microbiota…
- Conditions
- Maternal Exposure, Health Behavior, Infant Development, Child Development
- Trial name
- BRAVE (NCT03851120)
- Testing
- Probiotics and LC-PUFA (480 mg DHA), Psychosocial stimulation and healthy eating education
- Where
- Indonesia
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Pregnancy, Obesity
Nutrition and Pregnancy Intervention Study
A randomized double-blind placebo controlled intervention study with pregnant obese women (n=440) will be conducted. The intervention will involve consumption of fish oil and/or probiotic capsules from early pregnancy until 6…
- Conditions
- Pregnancy, Obesity, Gestational Diabetes Mellitus, Adiposity
- Trial name
- NCT01922791
- Where
- 2 sites in Finland
- Volunteers
- 439 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Oral Health
The Effects of an Oral Probiotic Intervention With or Without a Novel ADP-1 Toothpaste
Randomized double-blind, placebo-controlled trial on the effects of an oral probiotic intervention with or without a novel ADP-1 toothpaste Objective Determine the safety and effectiveness of oral probiotic intervention with or…
- Trial name
- NCT05330793
- Testing
- Oral probiotic
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- USANA Health Sciences
Stress, Cognition
Probiotic Intervention for Stress and Cognition
The effect of probiotics on stress and cognitive function in healthy adults with moderate stress
- Trial name
- NCT04931082
- Testing
- Probiotics
- Where
- Ireland
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Probi AB
VRE Colonization
Probiotic Efficacy in VRE Eradication
This study will evaluate the efficacy of a probiotic lactobacillus strain in eradicating VRE in non-symptomatic carriers after 4 weeks of treatment. It will also evaluate the long-term efficacy after 8,16 and 24 weeks.
- Trial name
- PROVE (NCT03560700)
- Testing
- lactobacillus probiotic strain
- Where
- Denmark
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Delayed Transit Time, Irregular Bowel Function
Influence of a Delivery System on the Efficacy of a Probiotic Intervention
In the proposed work we will evaluate the efficacy of a probiotic bacterium (Bifidobacterium animalis subsp. lactis BB12) delivered in a yogurt smoothie (organism to be added before or after fermentation) or as a supplement…
- Trial name
- NCT01399996
- Testing
- Yogurt smoothie without probiotic, Yogurt smoothie with probiotic added post fermentation, Yogurt smoothie with probiotic added pre-fermentation
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Penn State University
Obesity, Pregnancy
Gestational Obesity and Interventions With Probiotics or Fish Oil Trial
Obesity is one of the most concerning health issues in the modern world, especially due to its association with greater risk of developing a wide range of chronic diseases.
- Conditions
- Obesity, Pregnancy, Inflammation
- Trial name
- GOPROFIT (NCT03215784)
- Testing
- Fish Oil, Probiotic
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Probiotic Intervention
Probiotic Intervention, Bile Acids and Lipid Metabolism Metabolic Profile in Healthy Overweight Subjects.
Moderate hypercholesterolemia, metabolic alterations derived from overweight or obesity, and consequently and their related cardiovascular risks can be reduced through changes in lifestyle.
- Trial name
- PROBILIP (NCT05378230)
- Testing
- Probiotic preparation of three Lactobacillus plantarum strains (CECT 7527, CECT 7528, CECT 7529)
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Healthy 70 Street Market Vendors Working in Highly-polluted Areas of Turin
Biotics Intervention Oriented to Rescue From Environmental Pollution Inflammatory Responses
Improving air quality in urban areas represents a major public health challenge. In regions such as the Po Valley, airborne particulate matter (PM₁₀ and PM₂.₅) concentrations frequently exceed World Health Organization limits…
- Trial name
- BIOREPAIR (NCT07418489)
- Testing
- pro-postbiotic
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Osteopenia
Efficacy of a Probiotic Product on Bone Mineral Density (BMD) in Healthy Women in Early Post-menopausal Phase
The aim of the current study is to evaluate the efficacy of a probiotic product on bone mineral density (BMD) in healthy early post-menopausal women, compared to placebo.
- Trial name
- ProBone16 (NCT02722980)
- Testing
- : Probiotic capsules
- Where
- 2 sites in Sweden
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Probi AB
Dietary Intervention
Probiotic, Prebiotic and Synbiotic Effect on Immunity
The aim of the study is to investigate the effect of dietary supplements such as probiotic, prebiotic and synbiotic on the immune response to influenza vaccination and faecal microbiota in adult healthy volunteers.
- Trial name
- NCT01084434
- Testing
- probiotic, prebiotic, Synbiotic
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Reading
Obesity
Effect of a Synbiotic Supplement on a High-protein Diet
The objective of the trial is to study how a synbiotic treatment will affect weight loss and management in individuals enrolled in weight loss diet Profile®.
- Trial name
- NCT03123510
- Testing
- Bifidobacterium spp plus bimuno- galacto-oligosaccharides
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- South Dakota State University
Muscle Weakness
The Effect of GI Biome #7 on Gut Microbiome and Health of the Elderly
This study aims to investigate the effects of probiotics named GI Biome #7 on the gut microbiome and muscle strength in older adults aged 60 years or older.
- Trial name
- NCT05735418
- Testing
- GI Biome #7
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Childhood Obesity, Maternal Obesity During Childbirth
Prenatal Probiotic Intervention
This study will assess the feasibility of a randomized control trial in which the effects of probiotic supplementation throughout pregnancy on maternal insulin sensitivity and inflammation, as well offspring gene expression and…
- Conditions
- Childhood Obesity, Maternal Obesity During Childbirth, Insulin Resistance, Inflammation
- Trial name
- NCT03240419
- Testing
- Probiotics
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
VOLUNTEERS
Lactobacillus Plantarum 3547 Effects Over Inflammatory and Immunologic Markers
The purpose of this study is to evaluate the effects of the probiotic Lactobacillus plantarum 3547 over different inflammation and immune system markers on a healthy middle-aged group.
- Trial name
- NCT02622867
- Testing
- Lactobacillus plantarum 3547, Maltodextrin
- Where
- Spain
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Body Weight, Body Height
Safety and Tolerance Study of Three Probiotic Strains in Infants
Study to evaluate the safety and tolerance of three probiotic bacteria intake by healthy infants. Participants are divided at random and unknown to the researchers, in four groups, three of which receive one of three probiotic…
- Conditions
- Body Weight, Body Height, Head Circumference
- Trial name
- PROBINFANT (NCT02215304)
- Testing
- Bifidobacterium longum ssp infantis R0033, Lactobacillus helveticus R0052, Bifidobacterium bifidum R0071
- Where
- Spain
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- ProbiSearch SL
Obesity
The Effect of Intervention With Probiotic K56 on Body Fat Reduction in Obese Subjects
The aim of the present study was to investigate the effect of intervention with Lactobacillus paracasei K56 on body fat, metabolic risk markers,inflammatory markers and gut microbiota composition in obesity.
- Trial name
- NCT05192811
- Testing
- Lactobacillus paracasei K56
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fudan University