Clinical trials: Probiotic Supplement
Diabete Type 1
Effect of a Probiotic Supplement on Gut Microbiota and Glycemic Control in Patients With Type 1 Diabetes (PRODIAB)
This randomized, double-blind clinical trial aims to evaluate the effect of a probiotic supplement on gut microbiota composition and glycemic control in adults with type 1 diabetes mellitus.
- Trial name
- PRODIAB (NCT07062224)
- Testing
- Probiotic/Prebiotic Supplement
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Colic, Healthy Infants
Preventive Effect of a Dietary Supplement With Two Probiotic Limosilactobacillus Reuteri Strains on Excessive Crying and Colic in Healthy Newborns.
This study aims to demonstrate that a dietary supplement, which contains two strains of the probiotic L. reuteri is safe, well tolerated and able to reduce the incidence of colic and excessive crying/fussiness in healthy infants.
- Conditions
- Colic, Healthy Infants, Eczema Atopic Dermatitis
- Trial name
- ProtectPrevent (NCT07347743)
- Testing
- Two probiotic Limosilactobacillus reuteri strains
- Where
- Belgium
- Volunteers
- 768 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Aged, Healthy
New E-Service for a Dietary Approach to the Elderly
Ageing of the population is a major event in the world. Gerontological/geriatric literature unanimously indicate that physical exercise and diet are at present the two available fundamental approaches to contrast/prevent most of…
- Trial name
- RISTOMED (NCT01179789)
- Testing
- Optimal Diet, VSL#3®, AISA-5203-L
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Dietary Supplements, Probiotics
Cognitive and Metabolic Effects of a Probiotic Supplement
To examine the cognitive and metabolic effects of a probiotic supplement that is readily and already available for purchase in public drug stores.
- Conditions
- Dietary Supplements, Probiotics, Metabolism, Food Preferences
- Trial name
- NCT02005003
- Testing
- Inhibitory task, Blood samples, Feces collection
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Irritable Bowel Syndrome
Effect of Probiotic Supplement in Alleviating Functional Gastrointestinal Symptoms
The purpose of this study is to analyse the effect of a probiotic supplement on functional intestinal symptoms among subjects diagnosed with irritable bowel syndrome (IBS).
- Trial name
- NCT01728610
- Testing
- Probiotic (Active high), Probiotic (Active low)
- Where
- 2 sites in Finland
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- Danisco
Fecal Analysis
Fecal Recovery of the Probiotic Bacteria Lactobacillus Rhamnosus GG (LGG) and Bifidobacterium Animalis Subspecies Lactis BB-12 (BB-12) in Healthy Humans Following Daily Consumption of a Probiotic Supplement
The main hypothesis of this study is that there will be a significant increase of Lactobacillus rhamnosus GG (LGG) and Bifidobacterium lactis (BB-12) in the stool of healthy humans following daily consumption of a probiotic…
- Trial name
- LGG BB-12 (NCT01757054)
- Testing
- ProNutrients Probiotic
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Pfizer
Oral Health, Oral Disease
Levilactobacillus Brevis Oral Health
This RCT investigates the impact of an oral supplement containing the probiotic Levilactobacillus brevis CNCM I-5566 on various salivary indicators of oral health.
- Trial name
- LBOH-RCT (NCT06457724)
- Testing
- Levilactobacillus brevis CNCM I-5566
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of L'Aquila
Gastrointestinal, Gut Health
Consumer Health Study Aims to Evaluate the Safety, Tolerability and Impact of ED02 Probiotic Supplement on Gastrointestinal Outcomes
The Study Team identified Bifidobacterium pseudocatenulatum ED02 as a safe and effective probiotic strain isolated from a healthy human donor.
- Trial name
- NCT07423897
- Testing
- Bifidobacterium pseudocatenulatum
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Synbiotic Health
Healthy Adult Subjects
Dietary Supplement With and Without a Probiotic
Complex oligosaccharides can alter the gut microbiome by aiding in the growth of certain organisms, and possibly, inhibiting others. The synergy with a probiotic may enhance gastrointestinal colonization.
- Trial name
- NCT04433208
- Testing
- Complex oligosaccharide, Probiotic, PPI
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Prolacta Bioscience
Microbiota, Constipation
A Probiotic Blend Reduces Gastrointestinal Symptoms and Positively Impacts Microbiota Modulation in a Randomized Study
This randomized, placebo-controlled, double-blind study will determine the effect of daily supplementation with a probiotic blend in 60 apparently healthy men and women recruited at a single investigational center in Northeast…
- Conditions
- Microbiota, Constipation, Candida
- Trial name
- NCT05614726
- Testing
- 575mg [30 billion colony forming units] probiotic blend of Bifidobacterium breve, Lactobacillus acidophilus, Lacticaseibacillus rhamnosus, Saccharomyces boulardii, and alpha amylase
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- The Center for Applied Health Sciences, LLC
Premature Ovarian Failure (POF)
The Influence of Gut Microbiota on Ovarian Function: A Single-center, Randomized,Double Blind, Parallel-controlled, Exploratory Clinical Trial
In order to study the community profile of the intestinal microbiome in women with ovarian dysfunction, as well as the relationship between the changes in the intestinal microbiota and sex hormones, this study recruited 30 women…
- Trial name
- NCT07308327
- Testing
- Akk Gut Bacteria Supplement
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Songling Zhang
Healthy, Hyperuricemia, Gout
Acute Effects of a Urate-lowering Bacterial Therapeutic on Small Intestinal Transcriptomics and Glycomics in Healthy Subjects
This is a pilot study investigating how a novel probiotic supplement (BEO001), with and without a dietary fiber (beta-glucan), affects the lining of the small intestine in healthy people.
- Trial name
- Bugs4U-MoA (NCT07366749)
- Testing
- BEO001 Probiotic, BEO001 Probiotic + Beta-Glucan
- Where
- Sweden
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Cognitive Functions Perceptual Disturbances, Cognitive Function Abnormal
Effect of ExoBDNF Lactic Acid Bacteria Supplement on Cognitive Functions, Sleep and Psychological
This open-label, single-group, pre/post-test clinical study was conducted to investigate whether ExoBDNF probiotic supplementation could improve cognitive ability.
- Conditions
- Cognitive Functions Perceptual Disturbances, Cognitive Function Abnormal, Sleep, Psychological
- Trial name
- NCT06968299
- Testing
- ExoBDNF SWP-CGPA01 (Pediococcus acidilactici)Capsules
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- SunWay Biotech Co., LTD.
Intestinal Growth of Young Children
A Study on Efficacy of Feeding N1115 Probiotic Supplement to Young Children
The aim of the study is to examine the intervening effects of N1115 Probiotic Supplement (containing Junlebao Lp. N1115) on gut development in young children at the age of 6 month to 3 years by the way of a randomised…
- Trial name
- N1115Baby (NCT03416595)
- Testing
- N1115 Probiotic Supplement
- Where
- Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Junlebao Dairy Group Co., Ltd.
Constipation, Gastrointestinal Disorder
Effects of Probiotic Supplementation on Colonic Transit Time and Gastrointestinal Symptoms in Adults With Constipation.
To determine if Bifidobacterium lactis HN109 improves transit time and gastrointestinal symptoms in adults with constipation.
- Trial name
- NCT02189707
- Testing
- Probiotic Bifidobacterium 1x1010 cfu, Probiotic Bifidobacterium 1x109 cfu
- Where
- France
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Danisco Sweeteners Oy
Vaginal Microbiota, Microbiota
Effect of Hifas Intima Oral on Vaginal Microbiota in Healthy Women
The goal of this clinical trial was to learn whether the vaginal microbiota changed after healthy women aged 18 to 45 years took Hifas Intima, an oral food supplement, for 3 months.
- Conditions
- Vaginal Microbiota, Microbiota, Vaginal Microbiome
- Trial name
- NCT07715058
- Testing
- Hifas INTIMA Oral
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hifas da Terra S.L.
Healthy Adults
Prospective Tolerability Assessment of a Probiotic Dietary Supplement
The dietary supplement being investigated is a formula containing a combination of eight probiotic strains. The combination formula was developed to support general gastrointestinal and immune health.
- Trial name
- NCT04044144
- Testing
- Probiotic Dietary Supplement
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Metagenics, Inc.
Attention Deficit Hyperactivity Disorder
Effectiveness of Probiotic Supplement In Improving Attention Deficit Hyperactivity Disorder Symptoms
To study the effects of probiotic supplement in children with Attention-deficit hyperactivity disorder (ADHD),40 patients will be randomly allocated to two groups of intervention and placebo.
- Trial name
- NCT04333394
- Testing
- Probiotic
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Nutrition and Food Technology Institute
Gastrointestinal Symptoms, Bloating
Probiotic Supplementation Among Adults With Recurrent Gastrointestinal Symptoms
Participants experiencing recurrent gastrointestinal symptoms in this double-blind, randomized, controlled trial will receive either a commercially-available probiotic dietary supplement or placebo.
- Conditions
- Gastrointestinal Symptoms, Bloating, Gas, Indigestion
- Trial name
- NCT02277431
- Testing
- Probiotic dietary supplement (Trenev Trio®)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Pregnancy Related
Correlating Probiotic Dietary Supplements During Pregnancy With Maternal Microbiome Profiles
The overarching goal of this project is to compare the microbiome profiles of healthy pregnant women, both before and after the introduction of a probiotic supplement into the maternal diet.
- Trial name
- NCT03611647
- Testing
- Probiotic
- Where
- 3 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego