Clinical trials: Problem Drinking
Nonsuicidal Self Injury, Alcohol Abuse
Technology Enhanced Adolescent Mental Health (TEAM)
Adolescent nonsuicidal self-injury (NSSI) and alcohol misuse, alone and especially in combination, portend significant functional impairment in adulthood (e.g., relationship dysfunction, depression, suicidality).
- Conditions
- Nonsuicidal Self Injury, Alcohol Abuse, Vagus Nerve Stimulation
- Trial name
- TEAM (NCT05343039)
- Testing
- Non-invasive Transcutaneous Nerve Stimulation (tVNS), No Intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
Adolescent Drinking, Adolescent Problem Behavior
Mindfulness Mobile App to Reduce Adolescent Substance Use
Substance-abusing youth - especially those who are involved in the juvenile justice system - are at higher risk than nonusers for mental health problems, including depression, conduct problems, personality disorders, suicidal…
- Trial name
- Qlarity (NCT04027075)
- Testing
- Qlarity app users
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Social Skills, Self-Criticism
Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking
The purpose of this randomized controlled trial is to evaluate an intervention, Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS).
- Conditions
- Social Skills, Self-Criticism, Post-traumatic Stress Disorder, Depression
- Trial name
- NCT03488927
- Testing
- Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS)
- Where
- United States
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- University of New Hampshire
Alcohol Abuse or Dependence
Guided Self-Change Prevention Program for Alcohol Abuse in Adolescents in Educational Settings
This study corresponds to a pretest-posttest randomized experimental design with two arms. Arm 1 includes Guided Self-Change program, and Arm 2 a psychoeducational program to promote healthy habits.
- Trial name
- PREVENALC (NCT05281172)
- Testing
- Guided Self-Change therapy (GSC), Psychoeducation program about healthy habits
- Where
- Spain
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Alcohol Abuse
Web Intervention for Concerned Partners to Prevent Service Member Alcohol Abuse Abuse
The purpose of this study is to adapt and pilot-test a web-based intervention intended to help concerned partners provide support to service members with alcohol misuse and to begin development of a service member module based on…
- Trial name
- PC (NCT02073825)
- Testing
- Web Brief Intervention (WBI)
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- RAND
Risk Drinking,Diabetes, Hypertension, Osteoporosis, Infertility
Women's Health Habits Study
The purpose of this randomized trial is to test the effectiveness of screening and brief intervention for risk drinking by nonpregnant women with specific medical problems exacerbated by excessive alcohol consumption.
- Trial name
- WHHS (NCT00846638)
- Testing
- Brief Intervention, Diagnostic assessment
- Where
- United States
- Volunteers
- 611 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Alcohol Abuse, Drug Abuse
Effects of Levetiracetam (Keppra) on Alcohol Consumption
The overall goals of this study are to (1) expand knowledge about interactions of levetiracetam with alcohol by assessing the effects of levetiracetam compared to placebo in moderate and heavy social alcohol users and (2) to test…
- Trial name
- NCT01168687
- Testing
- Levetiracetam (Keppra)
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Alcohol Consumption, Alcohol Abuse/Dependence
Social Facilitation of Alcohol Effects and Alcohol Misuse in Young Adults
The purpose of this study is to understand social contexts and alcohol use. We hope to learn how being around peers affects alcohol consumption in young adults.
- Trial name
- PALS (NCT06627803)
- Testing
- Alcohol (Oral)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Alcohol Consumption, Alcohol Abuse
Web-Based Training for EAP Alcohol Screening, Brief Intervention, and Refer
The goal of the proposed research is to complete the development of a web-based program to train Employee Assistance Program (EAP) and EAP-affiliated managed behavioral health organization (MBHO) practitioners to conduct…
- Trial name
- BigAl2 (NCT02489032)
- Testing
- SBIRT Training & Support Tool, Waitlist Control
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Oregon Center for Applied Science, Inc.
Heavy Drinking, Mental Health Issue
Affirmative Psychotherapy for Sexual Minority Women's Mental and Behavioral Health
The purpose of this 2-arm randomized controlled trial is to assess the efficacy of a 10-session lesbian, gay, bisexual, transgender, and queer (LGBTQ)-affirmative cognitive-behavioral psychotherapy (CBT) delivered via telehealth…
- Trial name
- EQuIP (NCT05509166)
- Testing
- LGBTQ-affirmative Cognitive Behavioral Therapy, LGBTQ-affirmative Treatment-As-Usual
- Where
- United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Abuse, Alcohol Drinking
TREAT Child Alcohol Use Disorder (C-AUD) in Eastern Uganda
The investigators will investigate the existence of alcohol drinking among children living under adult supervision and care, living within the communities.
- Conditions
- Alcohol Abuse, Alcohol Drinking, Alcoholism, Alcohol Use Disorder
- Trial name
- TREAT C-AUD (NCT04743024)
- Where
- Uganda
- Volunteers
- 7,188 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Cardiovascular Diseases, Obesity Prevention
Team-based Learning Intervention to Prevent Risk Factors for Chronic Diseases - a Cluster Randomized Trial
Background: Chronic diseases, such as cardiovascular diseases, diabetes, and cancer, are a major global health issue. Their modifiable risk factors, including poor diet, physical inactivity, irregular sleep, tobacco use, and…
- Conditions
- Cardiovascular Diseases, Obesity Prevention, Sedentary Behaviors, Sleep Perception
- Trial name
- NCT06894134
- Testing
- Team-based learning
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Alcohol Abuse, Arteriosclerosis
Clinical Study of Ligustrazine in Treating Alcohol Addiction
Alcohol consumption is one of the most important risk factors for chronic non-communicable diseases in the population, and it is also the main cause of death from cancer, cardiovascular disease and lung disease, causing serious…
- Trial name
- NCT05942352
- Testing
- Ligustrazine by intravenously administration, Ligustrazine by mouth
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shenzhen Kangning Hospital
Alcohol Abuse
A Community-Based Strategy for Preventing Underage Drinking
This project evaluates a combination of policy and social influence interventions to reduce adolescent alcohol use and its sequelae.
- Trial name
- NCT02448134
- Testing
- Youth Access
- Where
- United States
- Volunteers
- 7,379 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Alcohol-Related Disorders, Alcohol Use Disorders
Tailored Mobile Text Messaging to Reduce Problem Drinking
This study is designed to develop and test a tailored adaptive text messaging/short message service (SMS) intervention for individuals interested in stopping or reducing their alcohol consumption; and test and compare it to…
- Conditions
- Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism
- Trial name
- NCT01885312
- Testing
- Adaptive Tailored Intervention, Consequence-based Intervention, Tailored, not adaptive, based Intervention
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Alcohol Abuse, Drug Abuse
A Web App for Patients With Alcohol and Drug Use Problems in Primary Care
The objective of this pilot study is to evaluate the feasibility and technical merit of a web application for patients in primary care called Check-up and Choices (CC).
- Trial name
- NCT01830114
- Testing
- Web app
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Behavior Therapy Associates, LLP
Substance Abuse
Integrated Care (iCare) at Mount Sinai to Improve Substance Use Diagnosis and Treatment Practices in HIV Clinic Settings
Substance abuse and dependence is highly prevalent among people living with HIV and significantly exacerbates morbidity and mortality and accelerates HIV disease progression.
- Trial name
- NCT03092596
- Testing
- Patient-administered screening tool, Patient health navigator-administered screening tool, Patient health navigator-assisted linkage to treatment
- Where
- United States
- Volunteers
- 3,358 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Alcoholism
Levetiracetam XR in Very Heavy Drinkers
The primary objectives of this study are to assess the efficacy of levetiracetam XR in increasing the percentage of subjects with no heavy drinking days and in reducing the weekly percentage of heavy drinking days in subjects…
- Trial name
- NCIG 002 (NCT00970814)
- Testing
- BBCET, Levetiracetam XR, Sugar Pill
- Where
- 5 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Depression, Anxiety, Alcohol Abuse
Cognitive-Behavioral Therapy for Young Adult Lesbian, Gay and Bisexual: Transdiagnostic Minority Stress Approach
Background: LGB people experience a large number of anxiety and mood disorders, and risk behaviors than heterosexual (Marshall et al., 2011).
- Conditions
- Depression, Anxiety, Alcohol Abuse, Sexual Compulsivity, Unsafe Sex
- Trial name
- NCT03980873
- Testing
- ESTEEM (Effective Sikills to Empower Effective Men)
- Where
- Spain
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Alcohol Abuse, Impulsive Behavior
Effects of Tolcapone on Decision Making and Alcohol Intake in Alcohol Users
The purpose of this study is to determine the effects of tolcapone on decision making and alcohol intake using a laboratory bar (on-site alcohol self-administration) in alcohol drinkers.
- Trial name
- NCT02740582
- Testing
- Tolcapone
- Where
- 2 sites in United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Jennifer Mitchell