Clinical trials: Procalcitonin
Pneumonia
Procalcitonin at Zero and 24 Hours as a Prognostic Factor in Patients With Pneumonia
Procalcitonin levels checked initially and at 24 hours will correlate with disease severity, morbidity, and mortality. Patients who have a higher procalcitonin level initially and at 24 hours will likely have higher qSOFA scores…
- Trial name
- NCT03711227
- Testing
- Procalcitonin lab test
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- Corewell Health South
Lower Resp Tract Infection
An Algorithm to Decide on Antibiotic Prescription in Lower Respiratory Tract Infection in Primary Care
The study is randomized clustered pragmatic trial whose objective is to decrease unnecessary antibiotic prescription in adult patients with lower respiratory tract infection managed at primary care level in Switzerland, using a…
- Trial name
- UltraPro (NCT03191071)
- Testing
- UltraPro, Procalcitonin, Blood sampling
- Where
- Switzerland
- Volunteers
- 469 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Infection
Biological Markers for the Diagnosis of Central Nervous System Infective Diseases
Bacterial meningitis is a potentially life-threatening disease that is associated with substantial neurological morbidity and mortality. Accurate diagnosis is essential to improve outcome and prevent antibiotic overuse.
- Trial name
- NCT02278016
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Procalcitonin, Infection
Procalcitonin as a Prognostic Predictor in Patients With Acute Infectious Disease Hospitalized in the Internal Medicine Department.
Procalcitonin is a well-known biomarker used to distinguish between bacterial and viral infections, assess a patient's risk category, and serve as a prognostic indicator.
- Conditions
- Procalcitonin, Infection, Internal Medicine Patients
- Trial name
- NCT07770334
- Testing
- No Interventions
- Volunteers
- 1,000 people
- Sponsor
- Barzilai Medical Center
Heart Failure, Infection
Improve Management of Heart Failure With Procalcitonin
Patients presenting to the Emergency Department with shortness of breath and (suspected) heart failure will be screened and randomized to either a standard of care or a procalcitonin-guided arm.
- Trial name
- IMPACT-EU (NCT02392689)
- Testing
- Procalcitonin
- Where
- 15 sites in Denmark, Germany and 2 more
- Volunteers
- 759 people
- Sponsor
- Brahms AG
Community-acquired Pneumonia
Clinical Pathway Based on Procalcitonin Levels for the Management of Community-acquired Pneumonia in Outpatients
A clinical protocol was developed for the management of adult outpatients with community-acquired pneumonia (CAP) and Pneumonia Severity Index risk classes I-II.
- Trial name
- NCT02600806
- Testing
- Azithromycin, Levofloxacin
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Cytoreductive Surgery
Does Serum Procalcitonin Levels Predict Sepsis in Patients Undergoing Cytoreductive Surgery
Serum procalcitonin levels will be considerably higher, for a longer period of time, in patients who develop sepsis compared to patients with SIRS or those who have an uncomplicated post-surgical recovery.
- Trial name
- NCT02189434
- Testing
- Serum procalcitonin lab draws
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Eastern Regional Medical Center
Pulmonary Disease, Chronic Obstructive, Respiratory Tract Infections
Viral Infections in Chronic Obstructive Pulmonary Disease (COPD) Exacerbations
The objectives of the study are to determine the prevalence of respiratory virus infections in COPD patients, during and outside acute exacerbation to explore the impact of these viral infections on the outcome of these patients…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Respiratory Tract Infections, Virus Diseases, Lung Diseases, Obstructive
- Trial name
- VICE (NCT00448604)
- Where
- Switzerland
- Volunteers
- 86 people
- Sponsor
- University Hospital, Geneva
Lung Infection
Reduction the Duration of Antibiotic Therapy in the Elderly (PROPAGE)
The main objective is to evaluate the interest of the repeated measurement of procalcitonin in patients with pulmonary infection to reduce the duration of antibiotic therapy in comparison with a conventional clinical strategy.
- Trial name
- PROPAGE (NCT02173613)
- Testing
- procalcitonine
- Where
- France
- Volunteers
- 117 people
- Sponsor
- University Hospital, Grenoble
Pneumonia Childhood
Severe Pneumonia Diagnostic in Pediatric Population by Lung Ultrasonography and Procalcitonin
Lung ultrasound (LUS) in combination with a biomarker has not yet been studied. The investigators propose a clinical trial where the primary aims are: 1.
- Trial name
- PROLUSP (NCT04217980)
- Testing
- Lung ultrasonography (LUS) or Chest X ray (CXR)
- Where
- 2 sites in Spain
- Volunteers
- 202 people
- Sponsor
- Fundació Sant Joan de Déu
Liver Transplant Infection
Evaluation of Procalcitonin (PCT) as a Marker of Infection Post Living Donated Liver Transplant
, the study aimed at assessing the frequency of rising procalcitonin associated with infectious complications in immunosuppressed LDLTRx.
- Trial name
- NCT03389360
- Testing
- procalcitonin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Hepatology & Tropical Medicine Research Institute
Sepsis, Severe
Procalcitonin in Diagnosis of Sepsis in Critically Ill Patient
correlation between procalcitonin levels and the severity of sepsis and it's possibility to be used as a prognostic marker in patients with sepsis and severe sepsis
- Trial name
- NCT04105400
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Sepsis
Procalcitonin as a Tool to Shorten Antibiotic Therapy in the ICU
Recently, biomarkers like procalcitonin have been studied in order to help physicians to decrease the duration of the antibiotic therapy.
- Trial name
- NCT01494675
- Testing
- procalcitonin measurement
- Where
- Brazil
- Volunteers
- 81 people
- Sponsor
- Hospital Israelita Albert Einstein
Respiratory Tract Infections, Urinary Tract Infections
TriVerity in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections and Suspected Sepsis
This study will analyze gene expression and other laboratory data from biological samples collected from participants with suspected respiratory, urinary, intra-abdominal, and/or skin \& soft tissue infections; or suspected…
- Conditions
- Respiratory Tract Infections, Urinary Tract Infections, Intra-Abdominal Infections, Skin and Soft Tissue Infection
- Trial name
- SEPSIS-SHIELD (NCT04094818)
- Testing
- TriVerity
- Where
- 26 sites in United States, Greece
- Volunteers
- 1,441 people
- Sponsor
- Inflammatix
Infection
NEWS2+Procalcitonin Association in Patients With Infection and Its Significance in Oncological Patients
This observational study aims to evaluate the prognostic significance of the combination of a clinical score (specifically, a score obtained through the measurement of multiple parameters such as blood pressure, body temperature…
- Trial name
- NCT06761118
- Where
- Italy
- Volunteers
- 1,041 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Osteomyelitis
Osteomyelitis: Procalcitonin to Diagnose and Monitor Osteomyelitis (PCT)
We plan a cohort study of 40 diabetic patients admitted to Parkland hospital with a foot infection. We will enroll a representative cross section of subjects with diabetic foot infection.
- Trial name
- PCT (NCT02308774)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Texas Southwestern Medical Center
Procalcitonin, Chronic Obstructive Pulmonary Disease
A Trial of Procalcitonin in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Current antibiotic prescription for patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is generally based on the Anthonisen criteria in The Global Initiative for Chronic Obstructive Pulmonary…
- Trial name
- NCT04682899
- Testing
- procalcitonin-guided antibiotic therapy, guideline-guided antibiotic therapy
- Volunteers
- 500 people
- Sponsor
- Capital Medical University
Sepsis, Diagnoses Disease
Sepsis Prediction by Monocyte Distribution Width and Procalcitonin
The mortality rate of sepsis remains as high as 30 to 40%. Early diagnosis and treatment of patients with sepsis reduce mortality significantly.
- Trial name
- NCT04322942
- Testing
- Monocyte Distribution Width
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- Chang Gung Memorial Hospital
Procalcitonin, Coronary Artery Bypass Grafting
Prospective Review of Procalcitonin After Cardiac Surgery
This study is designed to demonstrate the value of Procalcitonin (PCT) in assisting the rapid diagnosis of post- operative infection that includes elevation of Procalcitonin above and beyond the changes seen with the acute and…
- Trial name
- NCT01182688
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Tampa Bay Heart Foundation
Respiratory Tract Infections
Impact on PCT+ FilmArray RP2 Plus Use in LRTI Suspicion in Emergency Department
The real-time reporting of PCT results along with viral PCR data from the FilmArray® Respiratory Panel 2 plus in conjunction with an antimicrobial stewardship plan will aid in the proper withholding or withdrawing of antibiotics…
- Trial name
- PROARRAY (NCT03840603)
- Testing
- Film Array RP2 Assay guided
- Where
- France
- Volunteers
- 444 people
- Sponsor
- BioMérieux