Clinical trials: Procedural Pain
Procedural Pain, Cancer
Palm Stimulator Use During Peripheral Venous Catheterization
Purpose: The purpose of this study is to evaluate the effectiveness of a "Palm Stimulator" (a handheld device with blunt protrusions) in reducing pain, fear, and anxiety during peripheral venous catheterization (IV insertion) in…
- Conditions
- Procedural Pain, Cancer, Fear Needles, Anxiety
- Trial name
- NCT07387497
- Testing
- Palm Stimulator Group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Zeliha CENGİZ
Invasive Procedure
HYPIC Hypnosis for Procedural Pain in the Intensive Care Unit
Procedural pain in resuscitation is common in the conscious patient. However, analgesia and sedation may be impossible because of the acute pathology leading to resuscitation, comorbidities or the urgency of the invasive…
- Trial name
- HYPIC (NCT04129333)
- Testing
- Hypnosis, No hypnosis
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- Rennes University Hospital
Procedural Pain, Procedural Anxiety
Effects of Rain Stick and Musical Egg on Pain, Fear and Anxiety
This research will be conducted in a pre-test-post-test parallel group randomized controlled experimental study model to determine the effects of rain stick and musical egg applied during blood collection on pain, fear and…
- Conditions
- Procedural Pain, Procedural Anxiety, Fear Needles
- Trial name
- NCT06983093
- Testing
- Rain Stick, Musical Egg
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hakkari Universitesi
Neonatal Disease, Neonatal Disorder
Reducing Pain and Promoting Neurodevelopment Among Preterm Neonates
To determine the effects of multisensory stimulation and soft tissue therapy on procedural pain and neurodevelopment among neonates admitted to the NICU is the aim of the study.
- Trial name
- NCT04366102
- Testing
- Multisensory stimulation with soft tissue therapy, Routine hospital care
- Where
- India
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Oocyte Retrieval, Adverse Events
The Use of Virtual Reality Technology During Oocyte Retrieval for in Vitro Fertilization
Ultrasound-guided oocyte retrieval (OR) is a short, but oftentimes painful procedure, during which the follicles are punctured trans-vaginally to obtain oocytes for in vitro fertilization (IVF).
- Conditions
- Oocyte Retrieval, Adverse Events, Procedural Anxiety, Pain Intensity
- Trial name
- NCT06733701
- Testing
- VR-based intervention (VRReliever Software V0.3.4 fromXRHealth), VR headset without any scenery
- Volunteers
- 50 people
- Sponsor
- Mount Sinai Hospital, Canada
Pediatric Wounds, Procedural Pain
Virtual Reality Versus Game Card Distraction During Pediatric Wound Care
This completed randomized study compared two distraction approaches with standard care during pediatric open wound care. Ninety children aged 5-10 years were assigned to standard care alone, standard care plus distraction game…
- Conditions
- Pediatric Wounds, Procedural Pain, Procedure-Related Anxiety, Procedural Fear
- Trial name
- VR-WOUND (NCT07335666)
- Testing
- Distraction Game Cards, Virtual Reality Distraction
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Agri Ibrahim Cecen University
Patient Comfort
Evaluation of Pain and Discomfort in the Cardiac Catheterization Lab
The purpose of this study is to explore how the timing of procedural sedation medications influences patient comfort and satisfaction with sedation.
- Trial name
- NCT04490369
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Duke University
Pain, Procedural, Pain Management
The Effect of Two Method to Reducing Pain and Fear During Draw Blood From Children
This study was conducted to evaluate the effects of two different distraction methods on reducing pain and fear during blood collection from children. The study was conducted between January 2020 and May 2021.
- Conditions
- Pain, Procedural, Pain Management, Child, Only
- Trial name
- NCT05064657
- Testing
- Bubble blowing method
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Chronic Pain Post-Procedural
Effect of Intrathecal Morphine on Chronic Pain After Elective Caesarean Section
The incidence of chronic post-surgical pain (CPSP) after caesarean section (CS) is reported to be as high as 18%, reflecting it to be a significant clinical problem.
- Trial name
- NCT03451695
- Testing
- Morphine
- Where
- Nepal
- Volunteers
- 290 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Procedural Pain
Analgesic Effect of Breastmilk for Procedural Pain in Preterm Infants
Hypothesis: Breastmilk has a more powerful analgesic effect than oral sucrose to avoid procedural pain in preterm neonates. The objective is to test this hypothesis in a randomized, controlled study using a standardized and…
- Trial name
- BMoS (NCT00908401)
- Testing
- Breastmilk, Oral Sucrose
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Facial Wrinkles
A Study to Compare Subject Comfort During and After Injections With the Study Products and the Safety of the Non-FDA Approved Product for the Correction of Nasolabial Folds (NLFs)
The purpose of this research study is to compare subject comfort during and after injection with NADGL and Captique® Injectable Gel, in the nasolabial folds.
- Trial name
- NCT00417469
- Testing
- NADGL
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Genzyme, a Sanofi Company
Pain, Procedural, Distress, Procedural
Distraction for Reduction of Pain Associated With Venipuncture in the Pediatric Post-Transplant Population
Children with chronic diseases, particularly those who have received transplantation (e.g. cardiac, renal, or liver) are a population who undergo frequent painful procedures, such as venipuncture multiple times per week.
- Conditions
- Pain, Procedural, Distress, Procedural, Venipuncture
- Trial name
- NCT03004456
- Testing
- Distraction
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Columbia University
Analgesia Assessment
Bupivacaine Liposome Suspension Administration to Decreasre Peri-procedural Pain in Interventional Radiology (IR) Procedures
This study evaluates the use of liposomal bupivacaine (Exparel), a long-acting local anesthetic, for peri-procedural pain control in patients undergoing interventional radiology (IR) procedures.
- Trial name
- NCT07535411
- Testing
- Liposomal Bupivacaine (EXPAREL®)/Bupivacaine
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Anxiety, Pain, Procedural
Lavender Aromatherapy to Decrease Anxiety/Pain Perception During Office Hysteroscopy
Office hysteroscopy is an invaluable practice to treat a myriad of gynecological processes. However, a limiting factor is the perceived pain and anxiety.
- Trial name
- NCT06316934
- Testing
- Lavandula angustifolia, Aura Cacia
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Florida
Knee Prosthesis, Pain, Procedural
Comparison of Different Analgesic Nerve Blocks in Total Knee Replacement Surgery
The goal of this observational study is to compare the equivalent analgesic efficacy of three regional anesthesia techniques in total knee replacement surgery.
- Trial name
- NCT06422585
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Pain, Anxiety
Decreasing REcurrent Pain and Anxiety in Medical Procedures With a Pediatric Population: a Pilot Study
Children with injuries, including burns, experience severe pain intensity during medical procedures despite the increasing doses of analgesics.
- Conditions
- Pain, Anxiety, Burns, Child
- Trial name
- DREAM-P (NCT02977923)
- Testing
- VR distraction via Oculus Rift, Standard pharmacological treatment
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- St. Justine's Hospital
Procedural Pain, Pre-Term
Multimodal Approach to the Ontogenesis of Nociception in Very Preterm and Term Infants
The management of pain related to venipuncture remains insufficient in very preterm infants (VPI. The separation between the mother (father) and her(his) child can aggravate the short-term painful experience of the newborn.
- Conditions
- Procedural Pain, Pre-Term, Venipuncture
- Trial name
- NOCI-Prem (NCT05404594)
- Testing
- Maternal vocal contact
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Colonoscopy, Pain
Procedural Pain Treatment With Transmucosal Sublingual Fentanyl Tablet in Colonoscopy Patients
Colonoscopy is generally considered an invasive procedure that causes remarkable pain to the patient. The pain associated with the procedure is not caused by the insertion of the scope but from inflating of the colon in order to…
- Trial name
- Abstral (NCT01604187)
- Testing
- Fentanyl
- Where
- Finland
- Volunteers
- 158 people
- Sponsor
- Turku University Hospital
Procedural Pain Relief, Fear Pain
Pharmacological and Nonpharmacological Methods for Children in Venipuncture Pain
This study aimed to examine the effect of EMLA cream, cold spray, and Buzzy applied during venipuncture on the pain and fear levels of children aged 7-12 years.
- Trial name
- NCT06901271
- Testing
- EMLA Cream, Buzzy, Cold spray
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Aynur Aytekin Ozdemir
Procedural Pain, Acute Pain
Do Vacutainers With Animal Characters Reduce Fear and Anxiety?
The study was designed as a randomized controlled experimental research with the purpose of determining the effect of distraction by using vacutainers of three different animal characters.
- Conditions
- Procedural Pain, Acute Pain, Fear, Anxiety
- Trial name
- NCT06345911
- Testing
- Experimental group
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Burdur Mehmet Akif Ersoy University