Clinical trials: Procedural Pain, open to volunteers
Infertility
Virtual Reality for Pain and Anxiety During HyFoSy
This randomized controlled study will evaluate whether virtual reality (VR) reduces procedural pain and anxiety in women undergoing hysterosalpingo-foam sonography (HyFoSy), a minimally invasive ultrasound-based procedure used to…
- Trial name
- NCT07816393
- Testing
- virtual reality, rest
- Where
- Israel
- Volunteers
- 68 people
- Sponsor
- HaEmek Medical Center, Israel
Procedural Pain
To Explore the Optimal Dose of Dexmedetomidine for Skull Pin Fixation in Intracranial Surgery
Skull pin fixation is commonly used in intracranial surgery, which can increase the surgical field of view. Because skull pin fixation is a very irritating and painful medical treatment, it often results in tachycardia (>150-160…
- Trial name
- NCT06837818
- Testing
- Dexmedetomidine
- Volunteers
- 40 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Monitoring Noxious Events Using EEG-Derived Pain Indices, Procedural Sedation and Analgesia
qNOX Response to Nociceptive Motor Events During Procedural Sedation
The goal of this observational study is to evaluate whether the CONOX monitor can detect pain during sedation in patients undergoing urological procedures.
- Conditions
- Monitoring Noxious Events Using EEG-Derived Pain Indices, Procedural Sedation and Analgesia, Monitored Anesthesia Care
- Trial name
- MO-NOX (NCT07413848)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara University
Procedural Pain
Stress-Ball Distraction for Pain and Anxiety During Painful Procedures in Critically Ill Patients
This study will examine whether using a small hand-held stress ball during painful procedures can help critically ill adult patients feel less pain and anxiety.
- Trial name
- NCT07836842
- Testing
- Stress-Ball Distraction, Standard care
- Volunteers
- 104 people
- Sponsor
- Alexandria University
Epidural Anesthesia, Catheterisation
Epidural Catheter Placement Techniques by Anesthesia Residents: Success and Complications
This prospective observational study aims to evaluate the impact of epidural catheter placement techniques - loss of resistance (LOR) and hanging drop (HD) - on first-attempt success rates and procedural complications among…
- Conditions
- Epidural Anesthesia, Catheterisation, Education, Postoperative Pain
- Trial name
- EPİ-TECH (NCT07573007)
- Testing
- epidural catheter placement
- Where
- Turkey (Türkiye)
- Volunteers
- 440 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Pediatric Procedural Sedation
Intranasal Dexmedetomidine vs. Oral Chloral Hydrate for Pediatric Orthopedic Procedural Sedation
This prospective randomized controlled study will compare the effectiveness and safety of intranasal dexmedetomidine with oral chloral hydrate for procedural sedation in children undergoing painful orthopedic manipulation.
- Trial name
- NCT07768566
- Testing
- Dexmedetomidine, Chloral Hydrate
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Childrens Hospital
Procedural Pain
Comparison of Virtual Reality, EMLA Cream, and Standard Care for Pain During Blood Draws in Children
This randomized controlled trial evaluates methods to reduce pain during venipuncture in children aged 3 to 15 years. The study compares three approaches: virtual reality distraction using a VR headset, topical anesthesia with…
- Trial name
- NCT07763132
- Testing
- Virtual Reality Distraction, Lidocaine-Prilocaine Cream
- Where
- Czechia
- Volunteers
- 450 people
- Sponsor
- Marie Lulková
Procedural Anxiety, Procedural Pain
Oral Surgery Virtual Reality Glasses Study
The goal of this randomized trial is to investigate if using virtual reality (VR) glasses for patients who require non-emergent oral surgery procedures under intravenous (IV) sedation improves their overall experience compared to…
- Trial name
- NCT06723158
- Testing
- Virtual reality (VR) glasses with relaxation module
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Boston University
Peri-procedural Myocardial Infarction, Heart Failure Hospitalization
Clinical Evidence With Biomarker Confirmation for PPMI in PCI Clinical Trials Study
The goal of this prospective, multicenter, non-randomized observational study is to better identify and understand periprocedural myocardial injury among adults undergoing percutaneous coronary intervention (PCI) for stable…
- Conditions
- Peri-procedural Myocardial Infarction, Heart Failure Hospitalization, Mortality, Stable Angina Pectoris
- Trial name
- CEC-PPMI (NCT07848529)
- Testing
- Biomarker testing
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Baim Institute for Clinical Research
Breast Biopsy, Procedural Pain
The Effect of Using a Stress Ball on Pain, Anxiety, and Vital Signs During Breast Biopsy
Breast biopsy is an invasive diagnostic procedure commonly performed for the histopathological diagnosis of breast lesions and can be associated with anxiety and pain.
- Conditions
- Breast Biopsy, Procedural Pain, Anxiety, Vital Signs
- Trial name
- NCT07844395
- Testing
- Using a Stress Ball
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- TC Erciyes University
Colonoscopy Pain
Pre-procedural Risk Score-Based Endoscopist Assignment for Pain Reduction in Unsedated Colonoscopy
This multicenter randomized controlled trial evaluates whether a pre-procedural risk score-based endoscopist assignment strategy reduces intraprocedural pain in high-risk patients undergoing unsedated colonoscopy.
- Trial name
- NCT07713953
- Testing
- Risk Score-Based Endoscopist Assignment
- Where
- China
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Ningbo No. 1 Hospital
Procedural Sedation and Analgesia
PRedictors Of Maladaptive Behaviors in Children Undergoing Procedural SEDation
Procedural sedation for children outside of the operating room is a common practice in emergency departments, outpatient clinics, radiology suites, and dental offices for painful and anxiety-provoking procedures.
- Trial name
- PRoSEED (NCT07495826)
- Where
- 2 sites in Canada
- Volunteers
- 2,145 people
- Sponsor
- London Health Sciences Centre Research Institute
Elbow Pain, Chronic Pain
NonNarcotic Pain Control in Percutaneous Needle Tenotomy of Elbow
This study is a double-blind, randomized controlled trial comparing the effectiveness of oral acetaminophen, diclofenac, and tramadol in reducing the consumption of narcotic doses (primary outcome) and minimizing patients'…
- Trial name
- NCT06373978
- Testing
- Diclofenac, Tramadol, Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 92 people
- Sponsor
- The Cleveland Clinic
Pain Associated With Intrauterine Device Insertion
LI4 Acupuncture for Pain During Intrauterine Device Insertion
This study will evaluate whether acupuncture can reduce pain during intrauterine device (IUD) insertion. Women undergoing IUD insertion will be randomly assigned to receive either real acupuncture at the LI4 point on both hands…
- Trial name
- NCT07854015
- Testing
- LI4 Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Procedural Anxiety, Procedural Pain
VR-PAT for Pain and Anxiety Management During Pediatric Dermatologic Laser Procedures
This study will assess the feasibility and efficacy of our Virtual Reality Pain Alleviation Therapy (VR-PAT) for pain management during pediatric and young adult outpatient laser procedures and evaluate the impact of VR use on…
- Trial name
- NCT05645224
- Testing
- VR-PAT
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Nationwide Children's Hospital
Pediatric Anxiety
Non-Wearable Audiovisual Distraction for Children's Medical Anxiety in the ED
Pediatric emergency department (ED) visits often cause significant anxiety and stress for young patients due to unfamiliar environments and invasive medical procedures.
- Trial name
- NCT07761637
- Testing
- Non-Wearable Audiovisual Distraction, Routine ED Care
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
Abortion, First Trimester, Pain Management
Virtual Reality as a Method for Pain and Anxiety Control During First Trimester Procedural Abortion
The goal of this clinical trial is to learn whether use of a virtual reality (VR) headset showing a meditative nature video will help reduce pain and anxiety during a first trimester procedural abortion.
- Conditions
- Abortion, First Trimester, Pain Management, Pain After Surgery, Satisfaction
- Trial name
- CALM-VR (NCT07288047)
- Testing
- VR headset, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- Study Investigator
Procedural Sedation, Gastrointestinal Endoscopy
Therapeutic Effects of Music on Procedural Outcomes
This study will evaluate whether listening to low-tempo instrumental music during gastroscopy and/or colonoscopy can reduce the amount of sedative medication needed during the procedure.
- Conditions
- Procedural Sedation, Gastrointestinal Endoscopy, Music Intervention
- Trial name
- TEMPO (NCT07763860)
- Testing
- Low-Tempo Instrumental Music, Silent Audio Control
- Where
- Lebanon
- Volunteers
- 180 people
- Sponsor
- Bahaa Bou Dargham
Pain, Procedural Anxiety
Virtual Reality (VR) for Interventional Radiology (IR) Procedures
The goal of this clinical trial is to to utilize Virtual Reality during their interventional radiology procedure to help reduce any pain and anxiety experienced during the procedure in patients above the age of 8 undergoing…
- Trial name
- NCT07427862
- Testing
- Meta Oculus Quest Pro, Pico 4, Pico G3
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Children's Hospital Los Angeles
Pain During Outpatient Hysteroscopy
Environmental Visual Distraction With Nitrous Oxide During Outpatient Hysteroscopy: A Randomized Pilot Study
This document describes the protocol of a pilot randomized clinical study evaluating the effect of environmental visual distraction combined with nitrous oxide (N₂O) analgesia on the procedural experience of patients undergoing…
- Trial name
- VISION-HYST (NCT07473206)
- Testing
- Environmental Visual Distraction (Virtual Window), The control group receives nitrous oxide (N₂O) analgesia, which is a drug intervention, even though it is part of routine clinical practice.
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Ospedale degli Infermi di Biella