Clinical trials: Procedure Time, open to volunteers
Spasticity, Stroke
Early Botulinum Toxin for Muscle Stiffness Reduction in First-Time Stroke Patients: Improving Recovery and Independence
This study examines the early use of botulinum toxin in patients recovering from their first stroke to help reduce muscle stiffness and improve mobility.
- Conditions
- Spasticity, Stroke, Neurological Rehabilitation
- Trial name
- EARLY BOT-SPAS (NCT06811142)
- Testing
- Botulinum Toxin Type A (BoNT-A)
- Where
- Mexico
- Volunteers
- 200 people
- Sponsor
- Instituto Mexicano del Seguro Social
Chronic Insomnia, Overweight/Obesity
Cognitive Behavioral Therapy for Insomnia as an Adjunct to Time-restricted Eating on Weight Loss in Adults With Overweight or Obesity and Chronic Insomnia
Obesity (being overweight due to excess body fat) is a common health condition that increases the risk of developing problems such as diabetes, high blood pressure, and heart disease.
- Trial name
- NCT07770516
- Testing
- Flexible Time-restricted eating group (FTRE), Flexible Time-restricted eating plus cognitive behavioural therapy for insomnia group (CBTI+FTRE)
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
This Study Will Focus on In-office Dermatological Procedures
Split Face Study of the Duration of Local Anesthetics - Fifth Arm
This study will compare how long local anesthesia lasts when it is injected into different layers of the skin on the forearm. The investigators hypothesize that the numbing effect will last for different amounts of time depending…
- Trial name
- NCT07724418
- Testing
- Lidocaine HCl/Epinephrine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Removal of Femoral Arterial Sheath in ICU Patients, Complete Hemostasis
Preliminary Exploration of Factors Affecting Complete Hemostasis and Supine Time After Removal of Femoral Arterial Sheath in ICU Patients
Background:Following cardiac catheterization and arterial sheath removal, manual compression is applied until bleeding stops, after which a compression belt is used.
- Conditions
- Removal of Femoral Arterial Sheath in ICU Patients, Complete Hemostasis, Coronary Artery Disease, Percutaneous Coronary Intervention
- Trial name
- NCT07469397
- Testing
- Direct Inspection, medical records browsing
- Where
- Taiwan
- Volunteers
- 157 people
- Sponsor
- National Taiwan University Hospital
Obesity (Disorder), Morbid Obesity
Chrono-ALIGN: A Chronotype-Based Chrono-Nutrition Intervention in Post-Bariatric Patients
This randomized controlled trial will evaluate the impact of chrono-nutrition, a dietary approach that aligns meal timing with the body's circadian rhythms, on weight change, metabolic outcomes, appetite, and gut microbiota in…
- Conditions
- Obesity (Disorder), Morbid Obesity, Bariatric Sleeve Gastrectomy, Meal Time
- Trial name
- Chrono-ALIGN (NCT07324044)
- Testing
- Standard Post-Bariatric Care (Control), Early Time-Restricted Eating (eTRE), Chronotype-Based Chrono-Nutrition (CB-CN)
- Where
- Saudi Arabia
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- King Saud University
Acute Coronary Syndrome
OPT-CAD Score GUIded Dual ANtiplatelet De-esCalation Time
Monotherapy with a P2Y12 inhibitor after a minimum period of DAPT following percutaneous coronary intervention (PCI) is an emerging de-escalation antiplatelet strategy in recent years.
- Trial name
- OPT-GUIDNACE (NCT06216821)
- Testing
- standard DAPT, OPT-CAD score guided DAPT de-escalation
- Where
- China
- Volunteers
- 3,490 people
- Sponsor
- Shenyang Northern Hospital
Smoking ( Cigarette)
Ecological Momentary Assessment of Smoking Triggers, Needs, and Cigarette Forgoing
This study will evaluate a smartphone-based program designed to support adults who smoke cigarettes. Participants will use the spark app to complete brief surveys during the day and a daily evening survey about their smoking…
- Trial name
- spark Forgo (NCT07852845)
- Testing
- Non-Adaptive Motivational EMI, Adaptive Motivational EMI
- Volunteers
- 45 people
- Sponsor
- University of South Carolina
Colonoscopy Procedures, Sedation
Effects of Low-Dose Ketamine Added to Propofol Sedation During Colonoscopy
"This prospective observational study aims to evaluate the effects of adding low-dose ketamine (0.25 mg/kg) to standard propofol sedation on hemodynamic stability, sedation depth, and recovery times in adult patients undergoing…
- Trial name
- NCT07809230
- Testing
- Propofol group, Propofol + Ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ankara Etlik City Hospital
Cholecystectomy, Laparoscopic, Gynecologic Surgical Procedures
Synergistic Effect of Intravenous Lidocaine on Anesthetic Induction and Emergence in Patients Undergoing Laparoscopic Cholecystectomy or Gynecological Surgery
This study aims to evaluate the effect of intravenous lidocaine on consciousness changes during anesthesia in patients undergoing laparoscopic cholecystectomy or gynecologic surgery.
- Conditions
- Cholecystectomy, Laparoscopic, Gynecologic Surgical Procedures, Anesthesia and Procedure Related Time Intervals
- Trial name
- Li (NCT07193836)
- Testing
- Normal Saline (0.9% NaCl), Lidocaine, Lidocaine Bolus + Infusion
- Where
- China
- Volunteers
- 195 people
- Sponsor
- General Hospital of Ningxia Medical University
Anxiety, Anxiety Disorders
Implementation of a Just-In-Time Adaptive Intervention for Adolescent Anxiety
The goal of this clinical trial is to evaluate a smartphone based just-in-time adaptive intervention (JITAI) tool to deliver somatic behavioral recommendations for anxiety management among youth.
- Conditions
- Anxiety, Anxiety Disorders, Anxiety Disorder of Childhood
- Trial name
- NCT06946823
- Testing
- Just-In-Time Adaptive Intervention for Adolescent Anxiety
- Volunteers
- 50 people
- Sponsor
- Trustees of Dartmouth College
Mantle Cell Lymphoma
Zanubrutinib Plus Rituximab for Patients With Indolent Mantle Cell Lymphoma
Phase II, multicentre, randomised, open-label study to assess the benefit of early intervention with fixed duration, time-limited zanubrutinib-rituximab in indolent mantle cell lymphoma (MCL)
- Trial name
- ZEBRA (NCT05635162)
- Testing
- Zanubrutinib, Rituximab
- Where
- 13 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- University College, London
Opioid Use Disorder, mHealth
Personalized Addiction Treatment enHancement
Many patients stop medication-based treatments for Opioid Use Disorder (OUD) prematurely, placing them at increased risk for overdose and death.
- Conditions
- Opioid Use Disorder, mHealth, Peer Support
- Trial name
- Project Path (NCT07778394)
- Testing
- Vira Platform, Treatment-As-Usual
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rhode Island Hospital
Dental Caries, Periodontitis
Breaking the Cycle: Real-Time Family Oral Microbial Transmission Patterns as Intervention Targets
This study aims to understand how oral bacteria that cause tooth decay and gum disease spread among family members and whether treating multiple family members can reduce the return of these bacteria after dental treatment.
- Conditions
- Dental Caries, Periodontitis, Oral Microbiome, Bacterial Transmission
- Trial name
- NCT07674888
- Testing
- Professional Dental Plaque Disruption
- Where
- Canada
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Persistent Atrial Fibrillation
FIH Study of PFLotus in Persistent Atrial Fibrillation
Single-shot pulsed-field ablation (PFA) catheters maximize pulmonary vein isolation (PVI) efficiency but are limited for focal or linear ablation.
- Trial name
- PFLotus- FIH (NCT07301190)
- Testing
- Pulse field ablation with the PFLotus catheter
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The Third People's Hospital of Chengdu
Metabolic Syndrome
Effects of Restricted-time and Psychochrononutritional Feeding in People With Metabolic Syndrome
Metabolic syndrome is a cluster of risk factors, including abdominal obesity, high blood pressure, high triglycerides, and insulin resistance, that increase the risk of developing type 2 diabetes and cardiovascular disease.
- Trial name
- PSICRONUT (NCT07389603)
- Testing
- Time restricted eating, Psychochrononutritional intervention
- Where
- Mexico
- Volunteers
- 64 people
- Sponsor
- University of Guadalajara
Infertility, Poor Ovarian Reserve
Ovarian PRP Injections for Improved Embryo Quality Using Embryo Quality Score
Patients will have ovarian PRP treatments and embryo development will be observed using time-lapse imaging and AI software.
- Conditions
- Infertility, Poor Ovarian Reserve, Embryo Growth Disorder, in Vitro Fertilization
- Trial name
- NCT07020546
- Testing
- Ovarian Platelet-rich plasma (PRP) injections
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Generation Next Fertility
PTSD - Post Traumatic Stress Disorder
First-Line Intervention for PTSD - Intensive Treatment
The goal of this clinical trial is to learn if an intensive program can treat post-traumatic stress disorder (PTSD) in adults getting treatment for the first time, and whether it has lower societal costs.
- Trial name
- FLIP-IT (NCT06700590)
- Testing
- Intensive Treatment, Treatment as usual
- Where
- 4 sites in Netherlands
- Volunteers
- 186 people
- Sponsor
- ARQ National Psychotrauma Centre
Lyme Borreliosis, Physical Activity
Effectiveness of an Intervention Combining Adapted Physical Activity and Therapeutic Education in Patients With Chronic Symptoms Attributed to Lyme Borreliosis.
Lyme borreliosis, commonly known as Lyme disease, has been clinically described for more than a century, but has been officially recognized for 40 years, with the detection of the Borrelia bacterium by W.
- Conditions
- Lyme Borreliosis, Physical Activity, Lyme Borreliosis, Nervous System
- Trial name
- LyMouv' (NCT05641116)
- Testing
- physical activity program, Advice and recommendations of physical activity at home
- Where
- 2 sites in France
- Volunteers
- 62 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Bronchitis, Acute, Community-acquired Pneumonia
Multimodal Stewardship Programme to Improve Antibiotic Prescribing for Children With Lower Respiratory Tract Infections
Children with lower respiratory tract infection (LRTI) are still often prescribed antibiotics in ways that depart from national guidelines.
- Conditions
- Bronchitis, Acute, Community-acquired Pneumonia, Respiratory Tract Infections
- Trial name
- PRACTICE-LRTI (NCT07893834)
- Testing
- PRACTICE-LRTI multimodal antimicrobial stewardship programme
- Where
- Finland
- Volunteers
- 50,000 people
- Sponsor
- Tampere University
University Students
The Effects of Qigong Exercises on Acute Anxiety, Mood, and Reaction Time Among Occupational Therapy Students
The goal of this study is to examine the short-term effects of a single session of Baduanjin Qigong, a traditional mind-body exercise, on anxiety, mood, and reaction time in young adults studying occupational therapy.
- Trial name
- NCT07178275
- Testing
- Baduanjin Qigong, Passive Rest
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medipol University