Clinical trials: Processes, Metabolic
Hypertension, Diabetes
Development and Testing of a Sub-district Specific Model of 'Whole-of-government', and 'Whole-of-society' Approaches for the Prevention and Control of Non-communicable Diseases in a Sub-district of Bangladesh
Globally, non-communicable diseases (NCDs) are the leading cause of both mortality and morbidity. This intervention study aims to prevent and manage NCDs by adopting the World Health Organization's (WHO) comprehensive…
- Conditions
- Hypertension, Diabetes, Asthma, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT06453382
- Testing
- Behavioural change modification, Screening, NCD related knowledge practice and attitude
- Where
- Bangladesh
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- BRAC University
Obesity, Atherosclerosis
Observational Study of Early Metabolic and Vascular Changes in Obesity
To work against the increasing burden of obesity, the STYJOBS / EDECTA (STYrian Juvenile OBesity Study / Early DetECtion of Atherosclerosis) project was started at the Medical University of Graz in 2003.
- Conditions
- Obesity, Atherosclerosis, Inflammation, Adiponectin Deficiency
- Trial name
- STYJOBS (NCT00482924)
- Testing
- Lifestyle intervention
- Where
- Austria
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Healthy
"Beverage Hydration Index" of Commercial Therapeutic Beverages
The "beverage hydration index" (BHI) assesses the hydration potential of any consumable fluid relative to water. The BHI is a relatively new metric.
- Trial name
- NCT03262597
- Testing
- enterade, Pedialyte, Gatorade
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Sonoma State University
Exclusive Breastfeeding, Feeding Patterns
SPOON: Sustained Program for Improving Nutrition - Mexico
The primary goal of this study is to assess the impact of an innovative strategy to prevent undernutrition and obesity in early childhood in children 0-24 months in Mexico.
- Conditions
- Exclusive Breastfeeding, Feeding Patterns, Stunting, Obesity, Childhood
- Trial name
- NCT03752762
- Testing
- SQ-LNS, SPOON behavioral change strategy
- Where
- Mexico
- Volunteers
- healthy volunteers welcome
- Sponsor
- Inter-American Development Bank
Emergencies, Diabetes Mellitus
Geography of ED Use and Population Health
The goal of this study is to create predictive models of emergency care and metrics for population health that can be used to analyze how events like hospital closures or disasters like Hurricane Sandy affect health care…
- Trial name
- NCT03254524
- Testing
- Statewide Planning and Research Cooperative System Database
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Zinc Deficiency, Inflammation
Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc
The objective of the current study is to test the overarching hypothesis that the beef nutritive matrix is uniquely suited to direct dietary zinc to cellular compartments for improved metabolic function, leading to a greater…
- Conditions
- Zinc Deficiency, Inflammation, Metabolic Diseases, Vascular Diseases
- Trial name
- NCT05236374
- Testing
- Beef protein
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Atrial Fibrillation, Obesity and Obesity-related Medical Conditions
Metabolic Surgery for Atrial Fibrillation Elimination
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. It is estimated that between 3 and 6 million Americans are currently living with AF, while 12 million people in the United States will have AF in 2030.
- Trial name
- METSAFE (NCT07027969)
- Testing
- Roux-en-Y Gastric Bypass or Sleeve Gastrectomy, Anti-Obesity Medication (AOM) treatment
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ali Aminian
Chronic Obstructive Pulmonary Disease (COPD, Arterial Hypertension
Intervention to Improve the Adherence in Community Pharmacies
The ANM is the first initiative that puts advanced pharmaceutical care into practice in Andalusia (Spain). The aim of this is study is to evaluate the effectiveness of the intervention Assistance to New Medicines (ANM) in the…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD, Arterial Hypertension, Diabetes Mellitus
- Trial name
- NCT04195191
- Testing
- ANM
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Andalusian School of Public Health
Dehydration, Glaucoma
Drinking Habits of Glaucoma Patients and Age Matched Controls
The purpose of this study is to examine if a chronic dehydration is a risk factor for the developement or progression of some forms of glaucoma.
- Trial name
- NCT01503996
- Testing
- alter drinking habits
- Where
- Germany
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Diet, Healthy
Red Palm Olein on Inflammation and Gut Health
A parallel intervention was conducted to test the effect of consuming diets enriched with red palm olein (RPOO), extra virgin coconut oil (EVCO) and extra virgin olive oil (EVOO; positive control) in centrally obese individuals…
- Trial name
- RPO (NCT05791370)
- Testing
- A 12-week parallel dietary intervention
- Where
- Malaysia
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Postpartum Hemorrhage, Pregnancy Related
Pharmacokinetic Equivalence of Calcium Gluconate and Calcium Chloride in Parturients
Calcium is a life saving medicine in the care of parturients. It has many important uses including treatment of hypocalcemia, treatment of magnesium toxicity, prevention of hypocalcemia during blood transfusion (of citrate…
- Conditions
- Postpartum Hemorrhage, Pregnancy Related, Hypocalcemia, Parturition Complication
- Trial name
- NCT05973747
- Testing
- Calcium Gluconate, Calcium chloride
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obesity, Body Fat
Effects of Lipoic Acid and Eicosapentaenoic Acid (EPA) in Human Obesity
The aim of the study is to analyze the effects of Lipoic acid and/or EPA supplementation on weight loss, lipid profile, insulin resistance, oxidative and inflammation parameters, metabolomic profile as well as on adipose tissue…
- Conditions
- Obesity, Body Fat, Insulin Resistance
- Trial name
- OBEPALIP (NCT01138774)
- Testing
- Double blind dietary intervention with EPA and lipoic acid
- Where
- Spain
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Healthy Volunteers, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
This study is researching an experimental drug called ALN-PNP (called "study drug"). This is a first in human study. The study drug is not approved by any public health agency such as the United States Food and Drug…
- Trial name
- NCT05648214
- Testing
- ALN-PNP
- Where
- 6 sites in United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
Metabolic Syndrome, Vascular Injury
Therapeutic Strategies to Reduce Endothelial Ischemia-reperfusion Injury
The objective of this clinical trial is to better understand how lactate, a naturally occurring energy substance, can be used to lessen damage to the vascular system in adults with a high cardiovascular disease risk.
- Conditions
- Metabolic Syndrome, Vascular Injury, Ischemic Preconditioning, Endothelial Function (reactive Hyperemia)
- Trial name
- NCT06825143
- Testing
- Ischemic preconditioning, Intravenous lactate infusion, No ischemic preconditioning (control)
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Gary Van Guilder
Sexual Dysfunction, Endothelial Dysfunction
Comparing Effects of Diet, With or Without Exercise, on Sexual, Urinary and Endothelial Function, Inflammatory Profile and Quality of Life in Obese Men
This study aims to compare the effects of 8 months of diet modification, with or without exercise, on weight loss, sexual, urinary and endothelial function, systemic inflammation and quality of life in obese men.
- Conditions
- Sexual Dysfunction, Endothelial Dysfunction, Quality of Life, Inflammation
- Trial name
- NCT01642576
- Testing
- weight loss counselling
- Where
- Singapore
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Changi General Hospital
Diabetic Foot Ulcers
A Pilot Study of the Provant Therapy System in Subjects With Diabetic Foot Ulcers
The objective of this study is to compare the reduction in wound surface areas between patients with diabetic ulcers utilizing Provant's pulsed radio frequency energy therapy (PRFE) as an adjunct to standardized basic wound care…
- Trial name
- NCT00761176
- Testing
- The Provant Therapy System
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Regenesis Biomedical, Inc.
Urinary Tract Infections, Proteinuria
Scanadu Urine Device Validation Study Protocol
This study will test Scanadu Urine Device for clinical performance and usability.
- Conditions
- Urinary Tract Infections, Proteinuria, Ketone Urine, Hematuria
- Trial name
- NCT02973178
- Testing
- Scanadu Urine Device
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Scanadu, Inc.
Hepatic Encephalopathy, Liver Cirrhosis
Diagnosing Minimal Hepatic Encephalopathy
Our purpose is to 1. Examine the correlation between MDF in a resting EEG, recorded just before the CRT test, and the variance in reaction times indicated by the CRT index 2.
- Trial name
- MindTheLiver (NCT05433948)
- Testing
- Simultaneous EEG and CRT
- Where
- Denmark
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Chronic Kidney Disease
Diurnal Variation of Uremic Solutes in Peritoneal Dialysis
Study on the daytime variation of uremic retention solutes and markers of bone-mineral metabolism in patients with end-stage kidney disease treated with peritoneal dialysis
- Trial name
- NCT01093456
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Psoriasis
Efficacy of Two Algae Formulations on Lipid Metabolism, Inflammation and Oxidative Stress Status in Individuals With Psoriasis
Our overall goal is to evaluate the safety and efficacy of consumption of two algae formulations compared to a placebo on: degree of severity of skin lesions, plasma lipid levels, as well as other health-related markers, in…
- Trial name
- PCA (NCT01045395)
- Testing
- Corn starch, Unique Marine Algae Concentrate (UMAC), Golden brown algae
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
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